Age-period-cohort analysis: an illustration of the problems in assessing interaction in one observation per cell data

This paper discusses the specific problems of age-period-cohort (A-P-C) analysis within the general framework of interaction assessment for two-way cross-classified data with one observation per cell. The A-P-C multiple classification model containing the effects of age groups (rows), periods of observation (columns), and birth cohorts (diagonals of the two-way table) is characterized as one of a special class of models involving interaction terms assumed to have very specific forms. The so-called A-P-C identification problem, which results from the use of a particular interaction structure for detecting cohort effects, is shown to manifest itself in the form of an exact linear dependency among the columns of the design matrix. The precise relationship holding among these columns is derived, as is an explicit formula for the bias in the parameter estimates resulting from an incorrect specification of an assumed restriction on the parameters required to solve the normal equations. Current methods for modeling A-P-C data are critically reviewed, an illustrative numerical example is presented, and one potentially promising analysis strategy is discussed. However, gien the large number of possible sources for error in A-P-C analyses, it is strongly recommended that the results of such analyses be interpreted with a great deal of caution.