A cell means analysis of mixed linear models

The purpose of this paper is to describe a simple procedure for the estima-tion of parameters in the unbalanced mixed linear model. There are implications for hypothesis testing and interval estimation, A feature of these estimators is that they are expressed in terms of simple formulas. This has obvious advantages for computations and small sample analysis. In addition, the formulas suggest useful diagnostic procedures for assessing the quality of the data as well as possible defects in the model assumptions. The concepts are illustrated with several examples. Evidence is presented to indicate that, in cases of modest imbalance, these estimators are highly efficient and dominate AOV estimates over most of the parameter space. In cases of more extreme imbalance, the results are qualitatively the same but the estimators are less efficient than the AOV estimators for small values of the parameters. The extension of this method to factorial models with missing cells is not complete.