Estimation of odds ratios under order restrictions

A new method for estimating a set of odds ratios under an order restriction based on estimating equations is proposed. The method is applied to those of the conditional maximum likelihood estimators and the Mantel-Haenszel estimators. The estimators derived from the conditional likelihood estimating equations are shown to maximize the conditional likelihoods. It is also seen that the restricted estimators converge almost surely to the respective odds ratios when the respective sample sizes become large regularly. The restricted estimators are compared with the unrestricted maximum likelihood estimators by a Monte Carlo simulation. The simulation studies show that the restricted estimates improve the mean squared errors remarkably, while the Mantel-Haenszel type estimates are competitive with the conditional maximum likelihood estimates, being slightly worse.