| Abstract: | ABSTRACT Existing approaches for the statistical evaluation of the agreement of two quantitative assays in terms of individual means are either based on a linear model and some stringent assumptions or comparisons of averages of individual means. Furthermore, the related statistical tests for some of these approaches are not valid in the sense that the sizes of these tests are not exactly the same as the nominal size even asymptotically. In this paper we propose a new method, which produces exact statistical tests that are easy to compute. When independent replicates are available, the proposed method requires very little or no assumption on the individual error variances. Simulation results show that the proposed tests perform better than some existing tests. Some examples are presented for illustration. |
