Benchmark Analysis: Shopping with Proper Confidence |
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| Authors: | Walter W. Piegorsch R. Webster West |
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| Affiliation: | Department of Statistics, University of South Carolina, Columbia, SC 29208, USA. piegorsc@stat.sc.edu |
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| Abstract: | We discuss the issue of using benchmark doses for quantifying (excess) risk associated with exposure to environmental hazards. The paradigm of low-dose risk estimation in dose-response modeling is used as the primary application scenario. Emphasis is placed on making simultaneous inferences on benchmark doses when data are in the form of proportions, although the concepts translate easily to other forms of outcome data. |
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| Keywords: | Benchmark dose BMD BMDL low-dose extrapolation post hoc comparisons quantitative risk assessment simultaneous inferences |
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