血压与胰岛素水平关系的相关性研究

目的评价高血压及正常血压人群胰岛素水平的变化及血压各参数与胰岛素水平的相关性。方法入选原发性高血压患者156例,正常血压者138 例,收集如下资料:血压(收缩压、舒张压、脉压)、腹围、体重指数、空腹血糖、空腹胰岛素、餐后两小时胰岛素,血脂(甘油三脂、总胆固醇、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇),观察两组胰岛素水平及其相关危险因素的变化,并进行血压各参数与胰岛素水平相关性分析。结果高血压组较正常血压组胰岛素水平显著增高(P<0．05),收缩压和脉压与胰岛素水平显著正相关(r分别为0．365, 0．204,P分别<0．01、0．05)。结论高血压患者胰岛素水平升高,提示胰岛素抵抗在高血压的发病、进展中可能发挥重要作用。

The research of the Relationship of blood pressure and Insulin Resistance

Objiective We Investigated the level of Insulin in hypertension patients and normal blood pressure individuals, and evaluated the relationship of blood pressure and insulin resistance. Methods 156 hypertension patients and 138 normal blood pressure people Individuals were enrolled. Questionnaire, blood pressure(SBP,DBP,PP), waist circumference (WC) ,body mass index(BMI) , fasting glucose, insulin,blood lipid were carried out in all patients. Results The level of insulin increase significantly in hypertension patients compared to normal blood pressure people( P<0.05), SBP and PP was associated with insulin level (r =0.365, 0.204, P< 0.01,0.05), DBP was not correlated with insulin level . Conclusion The level of insulin was significantly higher in hypertension patients than normal blood pressure people, and IR may be a important role in developing of hypertension.