| 基于路径依赖视角的我国MAH制度实施演化博弈分析 |
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| 引用本文： | 戚湧,周星. 基于路径依赖视角的我国MAH制度实施演化博弈分析[J]. 中国管理科学, 2018, 26(10): 187-196. DOI: 10.16381/j.cnki.issn1003-207x.2018.10.018 |
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| 作者姓名： | 戚湧 周星 |
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| 作者单位： | 南京理工大学经济管理学院, 江苏 南京 210094 |
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| 基金项目： | 国家自然科学基金资助项目（71673135），江苏省社科基金重大项目（16ZD006） |
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| 摘 要： | MAH制度是国际公认通行的药品上市审批制度，具有生产形式多样化、技术转让自由、节约市场资源以及提升政府行政监管质量等优点。2016年，我国在北京、上海等10个省（市）开展药品上市许可持有人制度（MAH）试点工作。本文根据我国药品上市制度变迁的路径依赖问题，构建演化博弈模型，分别对由药品研发机构、药品生产企业构成的内部制度变迁和由政府、消费者构成的外部制度变迁进行分析，深入研究博弈主体行为的演化路径。研究表明：内部制度和外部制度路径依赖是制约我国医药产业发展和新药研发动力不足的主要原因，药品上市内部制度变迁主要通过规模效应和适应性预期影响药品研发机构和药品生产企业，从而产生药品上市内部制度路径依赖；药品上市外部制度变迁主要通过学习效应和协调效应影响政府和消费者，从而产生药品上市外部制度路径依赖。在此基础上，运用Matlab数值分析对药品制度变迁过程中的最优稳定策略进行探讨，解释了我国MAH制度变迁过程中存在的路径依赖问题，为完善我国MAH制度、破除路径依赖提供了一定参考。
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| 关 键 词： | 路径依赖 MAH制度 制度变迁 演化博弈 |
| 收稿时间： | 2017-06-30 |
| 修稿时间： | 2018-01-03 |
Game Analysis on the Implementation of China's Drug Listing System Based on Path Dependence |
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| QI Yong,ZHOU Xing. Game Analysis on the Implementation of China's Drug Listing System Based on Path Dependence[J]. Chinese Journal of Management Science, 2018, 26(10): 187-196. DOI: 10.16381/j.cnki.issn1003-207x.2018.10.018 |
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| Authors: | QI Yong ZHOU Xing |
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| Affiliation: | School of Economic & Management, Nanjing University of Science & Technology, Nanjing 210094, China |
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| Abstract: | MAH system is a drug listing system, which is internationally recognized, features the diversification of production form, freedom of technology transfer, saving market resources, improving the quality of government administrative supervision and so on. In 2016, China carries out the drug marketing authorization holder system (MAH) in 10 provinces (cities), such as Beijing and Shanghai. Based on the path-dependence problem of China's drug listing system, an evolutionary game model is constructed, analyzing the internal institutional changes made up by drug research and development agencies, and pharmaceutical production enterprises, and external institutional changes made by governments and consumers, and the evolution path of game subject behavior is deeply studied. Research has shown that the internal system and the external system path dependence are the main reasons that restrict the development of China's pharmaceutical industry and the insufficient power of the new drug research and development. The internal institutional changes of drug listed companies mainly affect drug research and development institutions and drug production enterprises through scale effect and adaptability expectation, thus leading to the path dependence of the internal system of drug listing; The external institutional change of drug market is mainly influenced by the learning effect and the coordination effect of the government and consumers, thus generating the path dependence of the external system of drug listing. Based on this, Matlab is used to carry out numerical analysis to discuss the optimal stability strategy in the process of drug system change. And it has explained the path dependence of the village during the transformation of MAH system in China, which provides some reference for perfecting the path dependence of MAH system in our country. |
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| Keywords: | path dependence MAH system institutional changes evolutionary game |
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