CBPS-based estimation for linear models with responses missing at random

In this article, based on the covariate balancing propensity score (CBPS), estimators for the regression coefficients and the population mean are obtained, when the responses of linear models are missing at random. It is proved that the proposed estimators are asymptotically normal. In simulation studies and real example, the proposed estimators show improved performance relative to usual augmented inverse probability weighted estimators.     

Inverse probability weighted estimators for single-index models with missing covariates

Abstract

In this article, we consider the inverse probability weighted estimators for a single-index model with missing covariates when the selection probabilities are known or unknown. It is shown that the estimator for the index parameter by using estimated selection probabilities has a smaller asymptotic variance than that with true selection probabilities, thus is more efficient. Therefore, the important Horvitz-Thompson property is verified for the index parameter in single index model. However, this difference disappears for the estimators of the link function. Some numerical examples and a real data application are also conducted to illustrate the performances of the estimators.     

A nonparametric inverse probability weighted estimation for functional data with missing response data at random

This paper considers the nonparametric inverse probability weighted estimation for functional data with missing response data at random. Under mild conditions, the asymptotic properties of the proposed estimation method are established. Based on the resampling method, the estimation of the asymptotic variance of the proposed estimator is obtained. Finally, the finite sample properties of the proposed estimation method are investigated via Monte Carlo simulation studies. A real data analysis is given to illustrate the use of the proposed method.     

Empirical likelihood for single index model with missing covariates at random

In this paper, we investigate the empirical-likelihood-based inference for the construction of confidence intervals and regions of the parameters of interest in single index models with missing covariates at random. An augmented inverse probability weighted-type empirical likelihood ratio for the parameters of interest is defined such that this ratio is asymptotically standard chi-squared. Our approach is to directly calibrate the empirical log-likelihood ratio, and does not need multiplication by an adjustment factor for the original ratio. Our bias-corrected empirical likelihood is self-scale invariant and no plug-in estimator for the limiting variance is needed. Some simulation studies are carried out to assess the performance of our proposed method.     

The weighted least square based estimators with censoring indicators missing at random

In this paper, we study linear regression analysis when some of the censoring indicators are missing at random. We define regression calibration estimate, imputation estimate and inverse probability weighted estimate for the regression coefficient vector based on the weighted least squared approach due to Stute (1993), and prove all the estimators are asymptotically normal. A simulation study was conducted to evaluate the finite properties of the proposed estimators, and a real data example is provided to illustrate our methods.     

Empirical likelihood for nonlinear models with missing responses

In this paper, a nonlinear model with response variables missing at random is studied. In order to improve the coverage accuracy for model parameters, the empirical likelihood (EL) ratio method is considered. On the complete data, the EL statistic for the parameters and its approximation have a χ² asymptotic distribution. When the responses are reconstituted using a semi-parametric method, the empirical log-likelihood on the response variables associated with the imputed data is also asymptotically χ². The Wilks theorem for EL on the parameters, based on reconstituted data, is also satisfied. These results can be used to construct the confidence region for the model parameters and the response variables. It is shown via Monte Carlo simulations that the EL methods outperform the normal approximation-based method in terms of coverage probability for the unknown parameter, including on the reconstituted data. The advantages of the proposed method are exemplified on real data.     

Nonparametric estimation for survival data with censoring indicators missing at random

In this paper, we consider the problem of hazard rate estimation in the presence of covariates, for survival data with censoring indicators missing at random. We propose in the context usually denoted by MAR (missing at random, in opposition to MCAR, missing completely at random, which requires an additional independence assumption), nonparametric adaptive strategies based on model selection methods for estimators admitting finite dimensional developments in functional orthonormal bases. Theoretical risk bounds are provided, they prove that the estimators behave well in term of mean square integrated error (MISE). Simulation experiments illustrate the statistical procedure.     

Semiparametric jump-preserving estimation for single-index models

Estimation of the single-index model with a discontinuous unknown link function is considered in this paper. Existed refined minimum average variance estimation (rMAVE) method can estimate the single-index parameter and unknown link function simultaneously by minimising the average pointwise conditional variance, where the conditional variance can be estimated using the local linear fit method with centred kernel function. When there are jumps in the link function, big biases around jumps can appear. For this reason, we embed the jump-preserving technique in the rMAVE method, then propose an adaptive jump-preserving estimation procedure for the single-index model. Concretely speaking, the conditional variance is obtained by the one among local linear fits with centred, left-sided and right-sided kernel functions who has minimum weighted residual mean squares. The resulting estimators can preserve the jumps well and also give smooth estimates of the continuity parts. Asymptotic properties are established under some mild conditions. Simulations and real data analysis show the proposed method works well.     

Conditional mode estimation for functional stationary ergodic data with responses missing at random

In this paper, we investigate the asymptotic properties of a non-parametric conditional mode estimation given a functional explanatory variable, when functional stationary ergodic data and missing at random responses are observed. First of all, we establish asymptotic properties for a conditional density estimator from which we derive almost sure convergence (with rate) and asymptotic normality of a conditional mode estimator. This new estimate take into account missing data, and a simulation study is performed to illustrate how this fact allows to get higher predictive performances than those obtained with standard estimates.     

Efficient estimation in a regression model with missing responses

This article examines methods to efficiently estimate the mean response in a linear model with an unknown error distribution under the assumption that the responses are missing at random. We show how the asymptotic variance is affected by the estimator of the regression parameter, and by the imputation method. To estimate the regression parameter, the ordinary least squares is efficient only if the error distribution happens to be normal. If the errors are not normal, then we propose a one step improvement estimator or a maximum empirical likelihood estimator to efficiently estimate the parameter.To investigate the imputation’s impact on the estimation of the mean response, we compare the listwise deletion method and the propensity score method (which do not use imputation at all), and two imputation methods. We demonstrate that listwise deletion and the propensity score method are inefficient. Partial imputation, where only the missing responses are imputed, is compared to full imputation, where both missing and non-missing responses are imputed. Our results reveal that, in general, full imputation is better than partial imputation. However, when the regression parameter is estimated very poorly, the partial imputation will outperform full imputation. The efficient estimator for the mean response is the full imputation estimator that utilizes an efficient estimator of the parameter.     

Mean estimation with data missing at random for functional covariables

In a missing-data setting, we want to estimate the mean of a scalar outcome, based on a sample in which an explanatory variable is observed for every subject while responses are missing by happenstance for some of them. We consider two kinds of estimates of the mean response when the explanatory variable is functional. One is based on the average of the predicted values and the second one is a functional adaptation of the Horvitz–Thompson estimator. We show that the infinite dimensionality of the problem does not affect the rates of convergence by stating that the estimates are root-n consistent, under missing at random (MAR) assumption. These asymptotic features are completed by simulated experiments illustrating the easiness of implementation and the good behaviour on finite sample sizes of the method. This is the first paper emphasizing that the insensitiveness of averaged estimates, well known in multivariate non-parametric statistics, remains true for an infinite-dimensional covariable. In this sense, this work opens the way for various other results of this kind in functional data analysis.     

Robust confidence regions for the semi-parametric regression model with responses missing at random

In this paper, a regression semi-parametric model is considered where responses are assumed to be missing at random. From the empirical likelihood function defined based on the rank-based estimating equation, robust confidence intervals/regions of the true regression coefficient are derived. Monte Carlo simulation experiments show that the proposed approach provides more accurate confidence intervals/regions compared to its normal approximation counterpart under different model error structure. The approach is also compared with the least squares approach, and its superiority is shown whenever the error distribution in the simulation study is heavy tailed or contaminated. Finally, a real data example is given to illustrate our proposed method.     

Empirical likelihood for the response mean of generalized linear models with missing at random responses

In this article, we present a new empirical likelihood ratio for constructing the confidence interval of the response mean of generalized linear models with missing at random responses. Compared with the existing methods, the proposal can avoid the so-called “curse of dimensionality” problem when the dimension of covariates is high, and is still chi-squared distributed asymptotically, nevertheless. Simulation studies are also provided to illustrate the performance of the developed method.     

Dimension reduction in estimating equations with covariates missing at random

To estimate parameters defined by estimating equations with covariates missing at random, we consider three bias-corrected nonparametric approaches based on inverse probability weighting, regression and augmented inverse probability weighting. However, when the dimension of covariates is not low, the estimation efficiency will be affected due to the curse of dimensionality. To address this issue, we propose a two-stage estimation procedure by using the dimension-reduced kernel estimation in conjunction with bias-corrected estimating equations. We show that the resulting three estimators are asymptotically equivalent and achieve the desirable properties. The impact of dimension reduction in nonparametric estimation of parameters is also investigated. The finite-sample performance of the proposed estimators is studied through simulation, and an application to an automobile data set is also presented.     

Statistical inference under imputation for proportional hazard model with missing covariates

Missing covariate data are common in biomedical studies. In this article, by using the non parametric kernel regression technique, a new imputation approach is developed for the Cox-proportional hazard regression model with missing covariates. This method achieves the same efficiency as the fully augmented weighted estimators (Qi et al. 2005. Journal of the American Statistical Association, 100:1250) and has a simpler form. The asymptotic properties of the proposed estimator are derived and analyzed. The comparisons between the proposed imputation method and several other existing methods are conducted via a number of simulation studies and a mouse leukemia data.     

Wavelet estimation of density for censored data with censoring indicator missing at random

In this paper, we define the nonlinear wavelet estimator of density for the right censoring model with the censoring indicator missing at random (MAR), and develop its asymptotic expression for mean integrated squared error (MISE). Unlike for kernel estimator, the MISE expression of the estimator is not affected by the presence of discontinuities in the curve. Meanwhile, asymptotic normality of the estimator is established. The proposed estimator can reduce to the estimator defined by Li [Non-linear wavelet-based density estimators under random censorship. J Statist Plann Inference. 2003;117(1):35–58] when the censoring indicator MAR does not occur and a bandwidth in non-parametric estimation is close to zero. Also, we define another two nonlinear wavelet estimators of the density. A simulation is done to show the performance of the three proposed estimators.     

Robust quasi-randomization-based estimation with ensemble learning for missing data

Missing data analysis requires assumptions about an outcome model or a response probability model to adjust for potential bias due to nonresponse. Doubly robust (DR) estimators are consistent if at least one of the models is correctly specified. Multiply robust (MR) estimators extend DR estimators by allowing for multiple models for both the outcome and/or response probability models and are consistent if at least one of the multiple models is correctly specified. We propose a robust quasi-randomization-based model approach to bring more protection against model misspecification than the existing DR and MR estimators, where any multiple semiparametric, nonparametric or machine learning models can be used for the outcome variable. The proposed estimator achieves unbiasedness by using a subsampling Rao–Blackwell method, given cell-homogenous response, regardless of any working models for the outcome. An unbiased variance estimation formula is proposed, which does not use any replicate jackknife or bootstrap methods. A simulation study shows that our proposed method outperforms the existing multiply robust estimators.