The monamine hypothesis,placebos, and problems of theory construction in psychology and psychiatry

Can there be scientific theories in psychology, medicine or psychiatry? I approach this question through an in-depth analysis of a typical experiment for clinical depression involving the monoamine hypothesis, drug action, and placebos. I begin my discussion with a reconstruction of Adolf Grünbaum’s conceptual analysis of what a placebo is. I then use his notion of “intentional placebo” to discuss a typical experiment using the monoamine hypothesis, two drugs, and a placebo. I focus on the theoretical aspects of the experiment, especially on the notion of causal explanation. I then raise five conceptual and methodological problems for theory construction. These problems focus on questions of the causal efficacy of placebos and drugs; ad hoc versus ceteris paribus explanations in biomedicine and psychology; and the falsifiability of the monoamine hypothesis. I conclude by pointing out the need for further, rigorous philosophical analysis concerning the possibility of theory construction in psychology, medicine or psychiatry.     

Culture‐Inclusive Theories of Self and Social Interaction: The Approach of Multiple Philosophical Paradigms

In view of the fact that culture‐inclusive psychology has been eluded or relatively ignored by mainstream psychology, the movement of indigenous psychology is destined to develop a new model of man that incorporates both causal psychology and intentional psychology as suggested by Vygotsky (1927). Following the principle of cultural psychology: “one mind, many mentalities” (Shweder et al., 1998), the Mandala Model of Self (Hwang, 2011a,b) and Face and Favor Model (Hwang, 1987, 2012) were constructed to represent the universal mechanisms of self and social interaction that can be applied to any culture; both models can be used as conceptual frameworks for analyzing mentalities of people in any given culture. Taking research works from Foundations of Chinese Psychology: Confucian Social Relation as exemplars (Hwang, 2012), this article illustrates how to construct culture‐inclusive theories of Confucianism by multiple philosophical paradigms. The mechanism of culture‐inclusive theory can be applied to explain qualitative research findings on lifeworld events of people in a particular society. It can also be utilized to predict results of quantitative research conducted to verify theoretical propositions in the scientific microworld by empirical methods.     

Conceptual Problems in the Development of a Psychological Notion of "Intuition"

Despite increased interest in "intuition" within cognitive psychology, the conceptual framework of this notion remains problematic. This paper argues that conceptual shortcomings stem from a tendency to ignore the philosophical heritage of intuition or to dismiss the relevance of this heritage to contemporary theory. The paper outlines major understandings of intuition within psychology and prominent philosophical traditions, highlighting important points of inconsistency in these and examining consequences of the inconsistency. It also considers psychological conceptions of intuition that more readily overlap with philosophical accounts and offers some suggestions toward a more philosophically informed notion of intuition relevant to contemporary psychological theory.     

Absent, Full and Partial Responsibility of the Psychopaths

The research into the typical behavioral pattern, motivational structure, and the value system of psychopaths can shed light on at least three aspects related to the analysis of the moral agency. First, it can help elucidating the emotive and cognitive conditions necessary for moral performance. Secondly, it can provide empirical evidence supporting the externalist theories of moral motivation. Finally, it can bring into greater focus our intuitive notion of the limits of moral responsibility. In this paper I shall concentrate on the last one—the question of responsibility of the amoralists, but the discussion will have an indirect bearing on the other two themes as well. My main reason for holding psychopaths morally responsible breaks down into two claims: the assumption that most ordinary people are morally responsible for their intentional actions (i.e., the rejection of hard determinism) and the denial that the psychopaths are qualitatively different from the non‐psychopaths. This thesis is further defended against two objections. First, I am arguing that the genetically based emotive deficiency of the psychopaths cannot be seen the factor condemning them to amoral existence, and thus cannot be cited as an exempting condition. Secondly, my position is defended against the claim that psychopaths are partly responsible for their actions. It is argued that the notion of partial responsibility is either incoherent or else rests on a false empirical premise. My conclusion is in agreement with, and provides a theoretical justification for, the position of most classifications of the persons with antisocial personality disorder in the DSM IV.     

Applying a Community Violence Framework to Understand the Impact of Immigration Enforcement Threat on Latino Children

Heeding the call put out by the New England Journal of Medicine (2017), we utilize an ecological–transactional model as a conceptual framework for understanding existing literature and for guiding future research on immigration enforcement threat and Latino child development. Using the World Health Organization's definition of violence, we draw on literature from psychology, medicine, social work, and developmental psychology to outline how the anti-immigrant climate in the United States and the threat of immigration enforcement practices in everyday spaces are experienced by some Latino children as psychological violence. Researchers, teachers, and practitioners are encouraged to be aware of how uncertainty and threat regarding familial safety adversely impacts the lives of Latino children in immigrant households, especially in charged, anti-immigrant climates.     

Szasz and His Interlocutors: Reconsidering Thomas Szasz's "Myth of Mental Illness" Thesis

It is a matter of some irony that psychiatry's most trenchant critic for over four decades is himself a psychiatrist. I refer to Thomas S. Szasz. Szasz's core thesis may be succinctly rendered: mental illness is a “myth”, a “metaphor” which serves only to obscure the social and ethical “problems in living” we face as human beings. This paper reconsiders the conceptual bases of Szasz's assault on psychiatry and assesses recent counter‐arguments of his critical interlocutors. It presents a defence of the Szaszian conception and emphasises the continuing relevance of his earliest work. Additionally, the paper discusses Szasz's thesis in light of the work of the influential French philosopher of medicine, Georges Canguilhem.     

The problems of Indian history

Most historians write Indian history from a Euro-American perspective. Two great historians illustrate the problem. Francis Parkman wrote the story of the Euro-Americans' victory over the Indians. Bernard Bailyn describes the social process of settlement neutrally, but ignores the Indians. So long as scholars define the American past in this way, Indian history has no significance on its own terms. If they focus only on “intersections” of Europeans and native “obstacles,” Indians are merely symbols. The many problems fall into three categories: structural, methodological, and conceptual.     

Social Psychology from Flat to Round: Intersubjectivity and Space in Peter Sloterdijk's Bubbles

In this paper I describe the relevance of philosopher Peter Sloterdijk's (1998/2011) book Bubbles for social psychology. Bubbles offers the opportunity for the development of what I call a round social psychology. This is in contrast to the flatness characteristic of some of the more influential contemporary varieties of social psychology. Flat social psychology stays close to the ground, and is focused on the coordination of action. Round social psychology describes the atmosphere that surrounds and makes interaction possible in the first place. It requires a theory that links intersubjectivity with spatiality. To describe flat social psychology I analyze the assumptions of three contemporary versions of social psychology: social cognition theory, Goffman's dramaturgy, and Gergen's relational psychology. I then describe in greater detail Sloterdijk's bubble philosophy and the characteristics of round social psychology.     

Social cognition,social neuroscience,and evolutionary social psychology: What's missing?

In this paper I argue that something important, and something social, is missing from contemporary accounts of social cognition, social neuroscience and evolutionary social psychology. Contemporary accounts of social cognition focus on cognition directed towards social objects, that is, towards persons and social groups. In contrast, early twentieth century accounts of socially engaged cognition focused upon beliefs and attitudes oriented to the represented beliefs and attitudes of members of social ‘reference groups’ and directed towards both social and non‐social objects. I argue that this earlier conception of socially engaged cognition should be integrated with contemporary research on social cognition, social neuroscience and evolutionary social psychology, since it poses a challenge but also an opportunity for these disciplines.     

Causal Mechanisms and the Philosophy of Causation

Lack of clarity about underlying philosophical commitments leads to lack of clarity at other levels of analysis. Here I show that the literature on so‐called “causal mechanisms” is rife with conceptual problems, stemming from insufficient rigor with respect to the metaphysics of causation.     

Nondestructive creation: Entrepreneurship and management research in the study of growth

Economists’ focus on institutions in explaining economic growth, while important, can obscure the significant role played by individual entrepreneurs and the process of entrepreneurship. The prevailing view of entrepreneurship in economics (which continues to shape prevailing public policies) centers on Schumpeter's famous concept of “creative destruction.” In the context of sustained high levels of economic growth, as in the recent American experience, I focus on a different feature of entrepreneurship—“nondestructive creation,” in which the uncoordinated contest of ideas and search for new applications of existing ideas generate growth. And this nondestructive creation should be analyzed and can be fostered.     

Pesticides,Neurodevelopmental Disagreement,and Bradford Hill’s Guidelines

Neurodevelopmental disorders such as autism affect one-eighth of all U.S. newborns. Yet scientists, accessing the same data and using Bradford-Hill guidelines, draw different conclusions about the causes of these disorders. They disagree about the pesticide-harm hypothesis, that typical United States prenatal pesticide exposure can cause neurodevelopmental damage. This article aims to discover whether apparent scientific disagreement about this hypothesis might be partly attributable to questionable interpretations of the Bradford-Hill causal guidelines. Key scientists, who claim to employ Bradford-Hill causal guidelines, yet fail to accept the pesticide-harm hypothesis, fall into errors of trimming the guidelines, requiring statistically-significant data, and ignoring semi-experimental evidence. However, the main scientists who accept the hypothesis appear to commit none of these errors. Although settling disagreement over the pesticide-harm hypothesis requires extensive analysis, this article suggests that at least some conflicts may arise because of questionable interpretations of the guidelines.     

Medicine and the paradigm of Neo-pragmatism a contribution to medical decision theory

Summary The epistemological paradigm of Systematic Neo-Pragmatism, supported by the author, is closely connected with the (semiotic-) pragmatical notion of model. The latter is expounded, and the models in medicine are characterised on the basis of flow charts and correlation-diagrams of the process of diagnosis. Furthermore, the neo-pragmatic concept of medicine is developed and it is shown how medicine is to be defined as a science of action. Finally, a holistic notion of reality in medicine is presented for which the interaction of subject and object as well as the unity of knowledge and action is important.This article is the revised version of a lecture delivered by the author at a symposium held at the Medizinische Universitätsklinik (university hospital), Cologne, 1 October 1982. The lecture has been published in German in Modelle und Realitäten in der Medizin, ed. R. Gross (Stuttgart-New York: Schattauer, 1983, pp. 7–22). For the present publication, the material has been brought up to date. I wish to thank Professor Gross, the editor of Modelle und Realitäten and the publishing house of Schattauer for their kind permission to reprint translated passages from this volume.     

Social Objects, Causality and Contingent Realism

This paper is a realist argument for the existence of "social objects". Social objects, I argue, are the outcome states of a contingent causal process and in turn posses causal properties. This argument has consequences for what we can mean by realism and consequences for the development of a realist methodology. Realism should abandon the notion of natural necessity in favour of a view that the "real" nature of the social world is contingent and necessity is only revealed in outcome states. This, I argue, has both theoretical and methodological implications and I develop my argument through two case studies, of homelessness and ethnicity.     

The Psychology of Environmentally Sustainable Behavior: Fitting Together Pieces of the Puzzle

This paper considers the main features of four general psychological approaches to the analysis of environmentally sustainable behavior (rational–economic, social dilemmas, attitude–behavior models, and applied behavioral analysis), and focuses on the problems inherent in applying each approach to this issue. It also details the utility of a holistic Social–Ecological Framework that I believe is useful for analyzing environmentally sustainable behavior. This approach draws on concepts from ecological psychology such as Gibson's (1979) notion of "affordances," and shows how such a method can account for and help us understand the limitations of traditional psychological approaches to environmentally sustainable behavior, and provides a general guiding framework for the formulation of environmental policy decisions and intervention programs.     

Delineating state groups through cluster analysis

This discussion is extracted from a larger research project in which an attempt is made to remedy the conceptual difficulties surrounding the “middle state” in international relations by defining the middle state vis-à-vis other types of states and without reference to any single dominant ontological framework. In this section of that project, the statistical technique of cluster analysis is used to demonstrate that the international state system contains three delineable state groups (labeled great, middle and small states). This article also demonstrates the use and usefulness of the cluster technique in international relations research.