Gene - Environment Interplay, Family Relationships, and Child Adjustment

This paper reviews behavioral genetic research from the past decade that has moved beyond simply studying the independent influences of genes and environments. The studies considered in this review have instead focused on understanding gene - environment interplay, including genotype - environment correlation ( rGE) and genotype × environment interaction (G × E). Studies have suggested that rGE is an important pathway through which family relationships are associated with child adjustment. Also important are direct causal influences of family relationships on child adjustment, independent of genetic confounds. Other studies have indicated that genetic and environmental influences on child adjustment are moderated by different levels of family relationships in G × E interactions. Genetically informed studies that have examined family relations have been critical to advancing our understanding of gene - environment interplay.     

Genetics and Peer Relations: A Review

Researchers have become increasingly interested in uncovering how genetic factors work together with the peer environment in influencing development. This article offers an overview of the state of knowledge. It first describes the different types of gene‐environment correlations (rGE) and gene‐environment interactions (GxE) that are of relevance for understanding the role of peer relations as well as the two main methodologies of genetically informed research, that is, the quantitative genetic approach and molecular genetics. This is followed by an overview of recent studies that examined different mechanisms of gene‐environment interplay involving peer relations in childhood and adolescence. The article concludes with an outline of future directions in genetically informed peer relations research as well as the implications for theory and practice.     

Combining the Social Relations Model and Behavioral Genetics to Explore the Etiology of Familial Interactions

SUMMARY

This review focuses on the Social Relations Model (SRM) and a genetic extension of this model as one approach for identifying the processes by which genetic factors influence familial exchanges (Kenny & La Voie, 1984). The basic SRM and its ability to decompose dyadic measures of family interaction into actor, partner and dyadic relationship effects is described followed by findings from 3 recent studies. Results indicate that much of familial interaction is in fact relationship specific, and not due to individual-level effects. We also discuss why and how the basic SRM is enriched through the incorporation of genetically sensitive designs and present results that suggest the importance of nonshared environmental contributions for both individual and dyadic level effects. Finally, directions for future family research are proposed including the use of genetically informative designs, the collection of round-robin robin data, and the incorporation of more diverse samples.     

我国生育政策城乡一体化方案与配套支持

我国生育政策城乡一体化是人口转变与社会发展之必然。一方面,城乡二元的生育政策很难体现城乡公平,用生育政策的优惠来弥补社会保障功能的匮乏这一做法已越来越不符合社会发展趋势;另一方面,二元生育政策本身的复杂性增加了政策执行过程中的成本与困难。生育政策城乡一体化应以城市与农村均实行一孩半政策作为既简化又稳妥的改革方案。生育政策城乡一体化还应配备配套措施,完善生育政策的评估指标,将少生与不生纳入评估范畴,促进城乡医疗、养老、教育等公共服务机会均等化、户籍管理动态化,还要正确理解人口老龄化,为生育政策城乡一体化提供良好的执行环境。     

Predicting Short- and Long-Term Mating Orientations: The Role of Sex and the Dark Tetrad

Previous literature has extensively considered factors that influence short- and long-term mating orientations, with specific attention given to individual differences (e.g., sex and personality). Although research has established the role “darker” personality traits (i.e., the dark triad) play in mating orientation, this triad has recently been reconceptualized as a tetrad. Due to this reconceptualization, the current study sought to establish the utility of sex and the dark tetrad in predicting individual short- and long-term mating orientations. In addition, as an alternative to previous methodology, the orientations were assessed using a continuous measure. A total of 464 participants, ages 18 to 69, completed an online questionnaire assessing dark tetrad traits and mating orientations. Results showed that sex, trait psychopathy, and trait sadism were significant predictors of a short-term mating orientation. For long-term mating orientations, there was no predictive utility of sex, but there were positive associations for narcissism and negative associations for psychopathy and sadism. These findings add further understanding of the predictors of mating orientation and the utility of the tetrad in predicting mating orientations. In addition, the findings offer future mating orientation studies an alternative measure to the traditional dichotomous format.     

A behavior genetic analysis of the tendency for youth to associate according to GPA

Behavior genetic research has revealed that many “environmental” variables are partially influenced by genetic factors. Known as gene–environment correlation (rGE), this line of scholarship provides insight on how and why individuals select into certain environments. Juxtaposing this body of evidence with research on peer group homophily—the tendency for peers to resemble one another on certain traits such as academic ability—raised two research hypotheses: (1) youth will associate with peers who receive grades similar to themselves (i.e., homophily for GPA); and (2) a portion of the variance in peer group GPA (i.e., the peer network average GPA) will be explained by individuals’ genetic self-selection into the peer group (rGE). The results supported both hypotheses by showing a strong predictive relationship between the target individual's GPA and that of his/her peers and by revealing that 72% of the variance in peer group GPA was explained by genetic influences.     

Genetic Studies of Pathological Gambling: A Review of Methodology and Analyses of Data from the Vietnam Era Twin Registry

Twin studies represent an important and powerful approach to estimating the relative contributions of environmental and genetic factors to the expression of psychiatric illnesses. In this article, we first explain the rationale for using large populations of monozygotic and dizygotic twin pairs to estimate genetic and environmental contributions to a disorder and the statistical modeling associated with this approach. We then review results from studies of the Vietnam Era Twin Registry that use this methodology to examine the etiology of pathological gambling (PG) behaviors. The results provide strong evidence for genetic contributions to the development of PG in men and set the foundation for future studies aimed at identifying the manner in which specific genes and environmental factors individually and in conjunction contribute to PG.     

Physical activity, genes, and lifetime predisposition to chronic disease

This mini-review summarizes the main associations between physical activity and chronic diseases and discusses the basic concepts related to the role of genetic factors in studies evaluating the effects of physical activity/exercise therapy on chronic disease prevention/treatment during the life course. Many observational cohort studies have shown that high physical activity during young adulthood or middle age is associated with reduced later life morbidity, mobility limitations and mortality. Physical activity or exercise therapy has a positive effect on health via many disease-specific mechanisms. The most consistent finding of the various randomized controlled studies conducted to date is that aerobic/functional capacity and/or muscle strength can be improved by exercise training among patients with different chronic diseases. Genes are known to play a role in chronic disease predisposition and to contribute to physical fitness levels, physical activity participation and ageing. Physical fitness, physical activity and health outcomes may be partly due to underlying genetic factors that have a favourable effect on all these traits (genetic pleiotropy). This means that in observational studies, the relationship between baseline activity and the later occurrence of diseases may not be interpreted entirely as causal. Increased knowledge on the role of nuclear genome, mitochondrial genome, epigenetics, telomeres and regulation of gene expression will increase our understanding of their relationships with physical activity and morbidity.     

Is Who Delivers the Treatment More Important than the Treatment Itself? The Role of The Therapist in Common Factors

In this article, we discuss the role of the therapist in change in couple and family therapy. We argue that the therapist is a key change ingredient in most successful therapy. We situate our discussion in the common factors debate and show how both broad and narrow common factor views involve the therapist as a central force. We review the research findings on the role of the therapist, highlight the strengths and weaknesses of this literature, and provide directions for future research. We then use this review as a foundation for our recommendations for theory integration, training, and practice.     

When Do People Deploy Genetic Determinism? A Review Pointing to the Need for Multi‐factorial Theories of Public Utilization of Scientific Discourses

For over two decades, scholars in the humanities and social sciences have attended warily and thoughtfully to the growing influence of biological and especially genetics‐based explanations of human behavior. Concern about genetic determinism has formed a focal point of this attention, because it was presumed to provide a lynchpin for discriminatory effects arising from genetics technologies. Substantial empirical research has now demonstrated that genetic determinism is in fact linked to discriminatory attitudes including prejudice, Social Dominance Orientation, sexism, and racism. Fortunately, however, the research has also indicated that most lay people’s deployment of genetic determinism is both limited and strategic, primarily serving self‐interests such as protecting valued behaviors (which are not health conducive) or avoiding blame. The disjunction between predictions based on existing social theories of discourse and empirical research on individual‐level practices highlights the need for a theoretical integration of biological biases, individual actions, and social structures in future social theories, especially theories about health behaviors, science studies, and public understanding of science.     

Psychosocial Factors of Migration: Adaptation and Application of the Health Belief Model

Psychosocial factors influencing behaviour play a central role in health research but seem under‐explored in migration research. This is unfortunate because these factors, which include knowledge, attitudes, beliefs, intentions and personality traits, provide essential and potentially effective handles for linking migration and migrant‐integration policies. We demonstrate that the health belief model (HBM) conceptualization of behavioural intentions contributes constructs that can further our understanding of migration intentions, thereby broadening the foundations for migration policies. We adapt the HBM to migration behaviour and then test it empirically by using survey data on international migration from West Africa and the Mediterranean region to the European Union. The results confirm that indicators of “perceived threat to living conditions”, “perceived benefits” and “perceived barriers to migration”, “cues to action” and “self‐efficacy” contribute considerably to the explanation of migration intentions. We conclude that psychosocial factors deserve greater prominence in migration theories and empirical research, and we recommend that migration surveys consider this framework to identify relevant indicators of psychosocial factors of international migration and develop appropriate survey questions to measure them.     

Genetics of pathological gambling

Pathological gambling (PG) is an impulse control disorder and a model behavioral addiction. Familial factors have been observed in clinical studies of pathological gamblers, and twin studies have demonstrated a genetic influence contributing to the development of PG. Serotonergic, noradrenergic, and dopaminergic dysfunction have been reported as biological factors contributing to the pathophysiology of PG. Molecular genetic techniques have been used to investigate the role of genetic factors in PG. Molecular genetic research has identified specific allele variants of candidate genes corresponding to these neurotransmitter systems to be associated with PG. Associations have been reported between pathological gamblers and allele variants of polymorphisms at dopamine receptor genes, the serotonin transporter gene, and the monoamine-oxidase A gene. Although preliminary data suggest that some of these differences are gender-specific, more research needs to be performed to substantiate gender-specific genetic contributions to the development of pathological gambling. The review of the current findings on genetics of PG suggests that liability to PG is in part mediated by genetic factors. Additional studies are needed to replicate and extend these findings, as well as to better understand the influence of specific allelic variants to differences in biological and behavioral functioning.     

Individual differences in infancy research: Letting the baby stand out from the crowd

Within the developmental literature, there is an often unspoken tension between studies that aim to capture broad scale, fairly universal nomothetic traits, and studies that focus on mechanisms and trajectories that are idiographic and bounded to some extent by systematic individual differences. The suitability of these approaches varies as a function of the specific research interests at hand. Although the approaches are interdependent, they have often proceeded as parallel research traditions. The current review notes some of the historical and empirical bases for this divide and suggests that each tradition would benefit from incorporating both methodological approaches to iteratively examine universal (nomothetic) phenomena and the individual differences (idiographic) factors that lead to variation in development. This work may help isolate underlying causal mechanisms, better understand current functioning, and predict long‐term developmental consequences. In doing so, we also highlight empirical and structural issues that need to be addressed to support this integration.     

The concept of the gene in psychiatric genetics and its consequences for the concept of mental illness

At this point in time, it is hard to say which consequences for the concept of mental illness result from modern genetics. Current research projects are trying to find significant statistical correlations between the diagnosis of a disease and a gene locus or an endophenotype. Up until now, there has not been any identification of alleles or mutations causing mental illness. In the meantime, the relations between the genetic basis and the disease are given the term “genetic vulnerability” as a placeholder; this concept simplifies the complex relations between the DNA and even the simplest cell functions observed in modern genetics. According to complex gene models like the systemic theory of DNA, it will not be possible to identify the genetic factors without a precise knowledge of the factors which modulate the gene expression. The significance of genetics as part of the concept of mental illness will not be able to be defined without further progress in developmental biology and psychology. Currently, psychological theory fails to acknowledge the complexity of the relationship between the DNA and the environment. Some starting points from which to develop such an understanding can be received from “developmental studies” and studies of the “psychophylogenesis”. An interdisciplinary concept of the biological basis of the psyche is needed.     

Personality and the enactment of emotion

The meaning of personality traits for social interaction was investigated by exploring the personality correlates of abilities to pose emotions. This framework focuses on individual differences in socio-emotional skills. Thirty one males and 37 females were videotaped while attempting to communicate seven basic emotions nonverbally (i.e., using standard content communications), and sending success was measured by showing edited videotapes to judges. Hypothesized relationships between acting ability and scores on the Jackson Personality Research Form and the Eysenck Personality Inventory were then examined. The findings were seen to have implications for predicting individual strengths and weaknesses in social interaction as a function of certain personality traits and for understanding person perception.This research was supported in part by NIMH Grant #RO3MH31453 and Intramural Research Grants from UC Riverside to Howard Friedman, and indirectly by the Biomedical Research Support Program of NIH (#RR077010-11). We would like to thank Louise M. Prince for her assistance.     

Nonverbal exchange: Past,present, and future

This paper provides a broad review and evaluation of the research on nonverbal exchange. The development of theoretical approaches to this research is traced over time and discussed. Relative strengths and weaknesses of past and present models are analyzed. Finally, specific recommendations are made for future research that will, we hope, extend our understanding of nonverbal exchange and its basic role in social interaction.     

Child safety at reunification: A case-control study of maltreatment recurrence following return home from substitute care

When considering reunification, child welfare caseworkers are faced with the difficult challenge of predicting which caretakers will be able to provide a safe environment for their children once they return home. Unfortunately, although an increasing number of studies have examined maltreatment recurrence during investigation and following case opening, little is known about the factors that predict maltreatment recurrence following reunification. Using a case-control design and information gathered from a child welfare administrative database and client case records, the current study examined the factors that predict short-term (i.e., within 60 days) maltreatment recurrence among 174 families with children returning home from their first stay in substitute care. From a variety of child, caretaker, placement, family environment, and service provision characteristics, seven variables uniquely added to the prediction of maltreatment recurrence: 1) child age, 2) caretaker mental illness, 3) number of placements, 4) type of placement, 5) length of time in placement, 6) number of children in the home at reunification, and 7) the interaction between household structure at reunification and the presence of siblings returned home with the index child. The implications of these findings for child welfare practice and future research are discussed in detail.     

HIV in young men who have sex with men: a review of epidemiology, risk and protective factors, and interventions

Epidemiological studies have found that young men who have sex with men (YMSM) represent the majority of young people infected with HIV annually in the United States. Further, they are one of the few risk groups to show an increase in the rate of infections in recent years. In addition to these disparities in prevalence and infection rates, there is an inequity in prevention and intervention research on this population. The purpose of this article is to review the existing YMSM literature on HIV epidemiology, correlates of risk, and intervention research. The article concludes that promising future directions for basic research include a focus on multiple clustering health issues, processes that promote resiliency, the role of family influences, and the development of parsimonious models of risk. In terms of intervention research, the article suggests that promising future directions include Internet-based intervention delivery, integration of biomedical and behavioral approaches, and interventions that go beyond the individual level to address partnership, structural, community, and network factors.     

Determinants of individual fertility and contraceptive use: a review and synthesis of the literature

This discussion, which reviews the fertility determinants literature from a sociopsychological or individual perspective, summarizes literature addressing the determinants of individual fertility, i.e., an individual's decision to use or not use an effective contraceptive method. Complete or definite answers about fertility determinants do not exist, but enough is known to provide an overview. From the 259 articles, monographs, and books examined and classified, 6 main classes of determinants were formed and analyzed: demographic; sociopsychological; experiential or behavioral; informational, including knowledge about reproduction and birth control; husband and wife interaction; and environmental. Gaps in the existing literature about these determinants are identified and a sociopsychological model integrating existing knowledge is proposed. In general, the following groups of individuals have relatively high fertility and/or relatively low or ineffective contraceptive use: low socioeconomic status, adolescents and people aged 40 and older, Catholics and highly religious, rural, many siblings, unemployed women or working women who do not attach great importance to their careers; and ethnic minorities. Sociopsychological determinants of fertility and contraceptive use have been classified into 2 groups: personality traits and values and attitudes. In general, the evidence linking values and attitudes to fertility-related behavior is stronger than personality traits, but some promising work in the personality area is being conducted. In general an early age at 1st marriage related to higher fertility, and duration of marriage positively associated with fertility as is a younger age at 1st birth. In general, there is a positive correlation between contraceptive knowledge and contraceptive behavior. Certain aspects of the husband/wife relationship, including the allocation of roles and responsibilities between husband and wife and the scope and frequency of their communication--are related to their fertility and contraceptive use. The extent to which family planning programs contribute to fertility decline, over and above the effects due to modernization and development, remains unanswered empirically. The following gaps in the literature were observed: the need for more research on the role of the male partner in determining fertility and contraceptive use, the experiential or behavioral determinants of fertility and contraceptive use, employment history, environmental aspects, and integration of the area into theoretical framework(s) capable of empirical verification.