Two step estimation for Neyman-Scott point process with inhomogeneous cluster centers

This paper is concerned with parameter estimation for the Neyman-Scott point process with inhomogeneous cluster centers. Inhomogeneity depends on spatial covariates. The regression parameters are estimated at the first step using a Poisson likelihood score function. Three estimation procedures (minimum contrast method based on a modified K function, composite likelihood and Bayesian methods) are introduced for estimation of clustering parameters at the second step. The performance of the estimation methods are studied and compared via a simulation study. This work has been motivated and illustrated by ecological studies of fish spatial distribution in an inland reservoir.     

Estimation using penalized quasilikelihood and quasi-pseudo-likelihood in Poisson mixed models

We consider two estimation schemes based on penalized quasilikelihood and quasi-pseudo-likelihood in Poisson mixed models. The asymptotic bias in regression coefficients and variance components estimated by penalized quasilikelihood (PQL) is studied for small values of the variance components. We show the PQL estimators of both regression coefficients and variance components in Poisson mixed models have a smaller order of bias compared to those for binomial data. Unbiased estimating equations based on quasi-pseudo-likelihood are proposed and are shown to yield consistent estimators under some regularity conditions. The finite sample performance of these two methods is compared through a simulation study.     

Bayesian mixture modeling for spatial Poisson process intensities,with applications to extreme value analysis

We propose a method for the analysis of a spatial point pattern, which is assumed to arise as a set of observations from a spatial nonhomogeneous Poisson process. The spatial point pattern is observed in a bounded region, which, for most applications, is taken to be a rectangle in the space where the process is defined. The method is based on modeling a density function, defined on this bounded region, that is directly related with the intensity function of the Poisson process. We develop a flexible nonparametric mixture model for this density using a bivariate Beta distribution for the mixture kernel and a Dirichlet process prior for the mixing distribution. Using posterior simulation methods, we obtain full inference for the intensity function and any other functional of the process that might be of interest. We discuss applications to problems where inference for clustering in the spatial point pattern is of interest. Moreover, we consider applications of the methodology to extreme value analysis problems. We illustrate the modeling approach with three previously published data sets. Two of the data sets are from forestry and consist of locations of trees. The third data set consists of extremes from the Dow Jones index over a period of 1303 days.     

Consistent parametric estimation of the intensity of a spatial–temporal point process

We consider conditions under which parametric estimates of the intensity of a spatial–temporal point process are consistent. Although the actual point process being estimated may not be Poisson, an estimate involving maximizing a function that corresponds exactly to the log-likelihood if the process is Poisson is consistent under certain simple conditions. A second estimate based on weighted least squares is also shown to be consistent under quite similar assumptions. The conditions for consistency are simple and easily verified, and examples are provided to illustrate the extent to which consistent estimation may be achieved. An important special case is when the point processes being estimated are in fact Poisson, though other important examples are explored as well.     

Empirical Uncertain Bayes Methods in Area‐level Models

Random effects model can account for the lack of fitting a regression model and increase precision of estimating area‐level means. However, in case that the synthetic mean provides accurate estimates, the prior distribution may inflate an estimation error. Thus, it is desirable to consider the uncertain prior distribution, which is expressed as the mixture of a one‐point distribution and a proper prior distribution. In this paper, we develop an empirical Bayes approach for estimating area‐level means, using the uncertain prior distribution in the context of a natural exponential family, which we call the empirical uncertain Bayes (EUB) method. The regression model considered in this paper includes the Poisson‐gamma and the binomial‐beta, and the normal‐normal (Fay–Herriot) model, which are typically used in small area estimation. We obtain the estimators of hyperparameters based on the marginal likelihood by using a well‐known expectation‐maximization algorithm and propose the EUB estimators of area means. For risk evaluation of the EUB estimator, we derive a second‐order unbiased estimator of a conditional mean squared error by using some techniques of numerical calculation. Through simulation studies and real data applications, we evaluate a performance of the EUB estimator and compare it with the usual empirical Bayes estimator.     

Local likelihood tracking of fault lines and boundaries

We suggest locally parametric methods for estimating curves, such as boundaries of density supports or fault lines in response surfaces, in a variety of spatial problems. The methods are based on spatial approximations to the local likelihood that the curve passes through a given point in the plane, as a function of that point. The local likelihood might be a regular likelihood computed locally, with kernel weights (e.g. in the case of support boundary estimation) or a local version of a likelihood ratio statistic (e.g. in fault line estimation). In either case, the local likelihood surface represents a function which is relatively large near the target curve, and relatively small elsewhere. Therefore, the curve may be estimated as a ridge line of the surface; we require only a numerical algorithm for tracking the projection of a ridge into the plane. This approach offers several potential advantages over alternative methods. First, the local (log-)likelihood surface can be graphed, and the degree of 'ridginess' assessed visually, to determine how the level of local smoothing should be varied in different spatial locations in order to emphasize the ridge and hence the curve adequately. Secondly, the local likelihood surface does not need to be computed in anything like its entirety; once we have a reasonable approximation to a point on the curve we may track it by numerically 'walking along' the ridge line. Thirdly, the method is appropriate without change for many different types of spatial explanatory variables—gridded, stochastic or otherwise. Three examples are explored in detail; fault lines in response surfaces and in intensity or density surfaces, and boundaries of supports of probability densities.     

Vector-borne infectious disease mapping with stochastic difference equations: an analysis of dengue disease in Malaysia

Few publications consider the estimation of relative risk for vector-borne infectious diseases. Most of these articles involve exploratory analysis that includes the study of covariates and their effects on disease distribution and the study of geographic information systems to integrate patient-related information. The aim of this paper is to introduce an alternative method of relative risk estimation based on discrete time–space stochastic SIR-SI models (susceptible–infective–recovered for human populations; susceptible–infective for vector populations) for the transmission of vector-borne infectious diseases, particularly dengue disease. First, we describe deterministic compartmental SIR-SI models that are suitable for dengue disease transmission. We then adapt these to develop corresponding discrete time–space stochastic SIR-SI models. Finally, we develop an alternative method of estimating the relative risk for dengue disease mapping based on these models and apply them to analyse dengue data from Malaysia. This new approach offers a better model for estimating the relative risk for dengue disease mapping compared with the other common approaches, because it takes into account the transmission process of the disease while allowing for covariates and spatial correlation between risks in adjacent regions.     

Bayesian computation for Log-Gaussian Cox processes: a comparative analysis of methods

The Log-Gaussian Cox process is a commonly used model for the analysis of spatial point pattern data. Fitting this model is difficult because of its doubly stochastic property, that is, it is a hierarchical combination of a Poisson process at the first level and a Gaussian process at the second level. Various methods have been proposed to estimate such a process, including traditional likelihood-based approaches as well as Bayesian methods. We focus here on Bayesian methods and several approaches that have been considered for model fitting within this framework, including Hamiltonian Monte Carlo, the Integrated nested Laplace approximation, and Variational Bayes. We consider these approaches and make comparisons with respect to statistical and computational efficiency. These comparisons are made through several simulation studies as well as through two applications, the first examining ecological data and the second involving neuroimaging data.     

Non nested model selection for spatial count regression models with application to health insurance

In this paper we consider spatial regression models for count data. We examine not only the Poisson distribution but also the generalized Poisson capable of modeling over-dispersion, the negative Binomial as well as the zero-inflated Poisson distribution which allows for excess zeros as possible response distribution. We add random spatial effects for modeling spatial dependency and develop and implement MCMC algorithms in $R$ for Bayesian estimation. The corresponding R library ‘spatcounts’ is available on CRAN. In an application the presented models are used to analyze the number of benefits received per patient in a German private health insurance company. Since the deviance information criterion is only appropriate for exponential family models, we use in addition the Vuong and Clarke test with a Schwarz correction to compare possibly non nested models. We illustrate how they can be used in a Bayesian context.     

Two-step estimation for inhomogeneous spatial point processes

Summary.  The paper is concerned with parameter estimation for inhomogeneous spatial point processes with a regression model for the intensity function and tractable second-order properties ( K -function). Regression parameters are estimated by using a Poisson likelihood score estimating function and in the second step minimum contrast estimation is applied for the residual clustering parameters. Asymptotic normality of parameter estimates is established under certain mixing conditions and we exemplify how the results may be applied in ecological studies of rainforests.     

Variance estimation of the risk difference when using propensity-score matching and weighting with time-to-event outcomes

Observational studies are increasingly being used in medicine to estimate the effects of treatments or exposures on outcomes. To minimize the potential for confounding when estimating treatment effects, propensity score methods are frequently implemented. Often outcomes are the time to event. While it is common to report the treatment effect as a relative effect, such as the hazard ratio, reporting the effect using an absolute measure of effect is also important. One commonly used absolute measure of effect is the risk difference or difference in probability of the occurrence of an event within a specified duration of follow-up between a treatment and comparison group. We first describe methods for point and variance estimation of the risk difference when using weighting or matching based on the propensity score when outcomes are time-to-event. Next, we conducted Monte Carlo simulations to compare the relative performance of these methods with respect to bias of the point estimate, accuracy of variance estimates, and coverage of estimated confidence intervals. The results of the simulation generally support the use of weighting methods (untrimmed ATT weights and IPTW) or caliper matching when the prevalence of treatment is low for point estimation. For standard error estimation the simulation results support the use of weighted robust standard errors, bootstrap methods, or matching with a naïve standard error (i.e., Greenwood method). The methods considered in the article are illustrated using a real-world example in which we estimate the effect of discharge prescribing of statins on patients hospitalized for acute myocardial infarction.     

Weighted empirical adaptive variance estimators for correlated data regression

Estimating equations based on marginal generalized linear models are useful for regression modelling of correlated data, but inference and testing require reliable estimates of standard errors. We introduce a class of variance estimators based on the weighted empirical variance of the estimating functions and show that an adaptive choice of weights allows reliable estimation both asymptotically and by simulation in finite samples. Connections with previous bootstrap and jackknife methods are explored. The effect of reliable variance estimation is illustrated in data on health effects of air pollution in King County, Washington.     

A regression approach for estimating the parameters of the covariance function of a stationary spatial random process

We consider the problem of estimating the parameters of the covariance function of a stationary spatial random process. In spatial statistics, there are widely used parametric forms for the covariance functions, and various methods for estimating the parameters have been proposed in the literature. We develop a method for estimating the parameters of the covariance function that is based on a regression approach. Our method utilizes pairs of observations whose distances are closest to a value h>0$h>0$ which is chosen in a way that the estimated correlation at distance h is a predetermined value. We demonstrate the effectiveness of our procedure by simulation studies and an application to a water pH data set. Simulation studies show that our method outperforms all well-known least squares-based approaches to the variogram estimation and is comparable to the maximum likelihood estimation of the parameters of the covariance function. We also show that under a mixing condition on the random field, the proposed estimator is consistent for standard one parameter models for stationary correlation functions.     

Extended Poisson INAR(1) processes with equidispersion,underdispersion and overdispersion

Real count data time series often show the phenomenon of the underdispersion and overdispersion. In this paper, we develop two extensions of the first-order integer-valued autoregressive process with Poisson innovations, based on binomial thinning, for modeling integer-valued time series with equidispersion, underdispersion, and overdispersion. The main properties of the models are derived. The methods of conditional maximum likelihood, Yule–Walker, and conditional least squares are used for estimating the parameters, and their asymptotic properties are established. We also use a test based on our processes for checking if the count time series considered is overdispersed or underdispersed. The proposed models are fitted to time series of the weekly number of syphilis cases and monthly counts of family violence illustrating its capabilities in challenging the overdispersed and underdispersed count data.     

Application of Stein Rules to Combination Forecasting

We propose some Stein-rule combination forecasting methods that are designed to ameliorate the estimation risk inherent in making operational the variance–covariance method for constructing combination weights. By Monte Carlo simulation, it is shown that this amelioration can be substantial in many cases. Moreover, generalized Stein-rule combinations are proposed that offer the user the opportunity to enhance combination forecasting performance when shrinking the feasible variance–covariance weights toward a fortuitous shrinkage point. In an empirical exercise, the proposed Stein-rule combinations performed well relative to competing combination methods.     

A Class of Weighted Estimating Equations for Semiparametric Transformation Models with Missing Covariates

In survival analysis, covariate measurements often contain missing observations; ignoring this feature can lead to invalid inference. We propose a class of weighted estimating equations for right‐censored data with missing covariates under semiparametric transformation models. Time‐specific and subject‐specific weights are accommodated in the formulation of the weighted estimating equations. We establish unified results for estimating missingness probabilities that cover both parametric and non‐parametric modelling schemes. To improve estimation efficiency, the weighted estimating equations are augmented by a new set of unbiased estimating equations. The resultant estimator has the so‐called ‘double robustness’ property and is optimal within a class of consistent estimators.     

Bayesian Single Changepoint Estimation in a Parameter‐driven Model

In this paper, we consider the problem of estimating a single changepoint in a parameter‐driven model. The model – an extension of the Poisson regression model – accounts for serial correlation through a latent process incorporated in its mean function. Emphasis is placed on the changepoint characterization with changes in the parameters of the model. The model is fully implemented within the Bayesian framework. We develop a RJMCMC algorithm for parameter estimation and model determination. The algorithm embeds well‐devised Metropolis–Hastings procedures for estimating the missing values of the latent process through data augmentation and the changepoint. The methodology is illustrated using data on monthly counts of claimants collecting wage loss benefit for injuries in the workplace and an analysis of presidential uses of force in the USA.     

Estimation of the intensity function of an inhomogeneous Poisson process with a change‐point

Recent work on point processes includes studying posterior convergence rates of estimating a continuous intensity function. In this article, convergence rates for estimating the intensity function and change‐point are derived for the more general case of a piecewise continuous intensity function. We study the problem of estimating the intensity function of an inhomogeneous Poisson process with a change‐point using non‐parametric Bayesian methods. An Markov Chain Monte Carlo (MCMC) algorithm is proposed to obtain estimates of the intensity function and the change‐point which is illustrated using simulation studies and applications. The Canadian Journal of Statistics 47: 604–618; 2019 © 2019 Statistical Society of Canada     

What is the effective sample size of a spatial point process?

Point process models are a natural approach for modelling data that arise as point events. In the case of Poisson counts, these may be fitted easily as a weighted Poisson regression. Point processes lack the notion of sample size. This is problematic for model selection, because various classical criteria such as the Bayesian information criterion (BIC) are a function of the sample size, n, and are derived in an asymptotic framework where n tends to infinity. In this paper, we develop an asymptotic result for Poisson point process models in which the observed number of point events, m, plays the role that sample size does in the classical regression context. Following from this result, we derive a version of BIC for point process models, and when fitted via penalised likelihood, conditions for the LASSO penalty that ensure consistency in estimation and the oracle property. We discuss challenges extending these results to the wider class of Gibbs models, of which the Poisson point process model is a special case.     

Expected estimating equations to accommodate covariate measurement error

Estimating equations which are not necessarily likelihood-based score equations are becoming increasingly popular for estimating regression model parameters. This paper is concerned with estimation based on general estimating equations when true covariate data are missing for all the study subjects, but surrogate or mismeasured covariates are available instead. The method is motivated by the covariate measurement error problem in marginal or partly conditional regression of longitudinal data. We propose to base estimation on the expectation of the complete data estimating equation conditioned on available data. The regression parameters and other nuisance parameters are estimated simultaneously by solving the resulting estimating equations. The expected estimating equation (EEE) estimator is equal to the maximum likelihood estimator if the complete data scores are likelihood scores and conditioning is with respect to all the available data. A pseudo-EEE estimator, which requires less computation, is also investigated. Asymptotic distribution theory is derived. Small sample simulations are conducted when the error process is an order 1 autoregressive model. Regression calibration is extended to this setting and compared with the EEE approach. We demonstrate the methods on data from a longitudinal study of the relationship between childhood growth and adult obesity.