Simultaneous estimation for non-crossing multiple quantile regression with right censored data

In this paper, we consider the estimation problem of multiple conditional quantile functions with right censored survival data. To account for censoring in estimating a quantile function, weighted quantile regression (WQR) has been developed by using inverse-censoring-probability weights. However, the estimated quantile functions from the WQR often cross each other and consequently violate the basic properties of quantiles. To avoid quantile crossing, we propose non-crossing weighted multiple quantile regression (NWQR), which estimates multiple conditional quantile functions simultaneously. We further propose the adaptive sup-norm regularized NWQR (ANWQR) to perform simultaneous estimation and variable selection. The large sample properties of the NWQR and ANWQR estimators are established under certain regularity conditions. The proposed methods are evaluated through simulation studies and analysis of a real data set.     

Buckley–James-type estimation of quantile regression with recurrent gap time data

In longitudinal studies, an individual may potentially undergo a series of repeated recurrence events. The gap times, which are referred to as the times between successive recurrent events, are typically the outcome variables of interest. Various regression models have been developed in order to evaluate covariate effects on gap times based on recurrence event data. The proportional hazards model, additive hazards model, and the accelerated failure time model are all notable examples. Quantile regression is a useful alternative to the aforementioned models for survival analysis since it can provide great flexibility to assess covariate effects on the entire distribution of the gap time. In order to analyze recurrence gap time data, we must overcome the problem of the last gap time subjected to induced dependent censoring, when numbers of recurrent events exceed one time. In this paper, we adopt the Buckley–James-type estimation method in order to construct a weighted estimation equation for regression coefficients under the quantile model, and develop an iterative procedure to obtain the estimates. We use extensive simulation studies to evaluate the finite-sample performance of the proposed estimator. Finally, analysis of bladder cancer data is presented as an illustration of our proposed methodology.     

Estimation and variable selection for partially functional linear models

In this paper, a new estimation procedure based on composite quantile regression and functional principal component analysis (PCA) method is proposed for the partially functional linear regression models (PFLRMs). The proposed estimation method can simultaneously estimate both the parametric regression coefficients and functional coefficient components without specification of the error distributions. The proposed estimation method is shown to be more efficient empirically for non-normal random error, especially for Cauchy error, and almost as efficient for normal random errors. Furthermore, based on the proposed estimation procedure, we use the penalized composite quantile regression method to study variable selection for parametric part in the PFLRMs. Under certain regularity conditions, consistency, asymptotic normality, and Oracle property of the resulting estimators are derived. Simulation studies and a real data analysis are conducted to assess the finite sample performance of the proposed methods.     

A Quantile Survival Model for Censored Data

In this paper we propose a quantile survival model to analyze censored data. This approach provides a very effective way to construct a proper model for the survival time conditional on some covariates. Once a quantile survival model for the censored data is established, the survival density, survival or hazard functions of the survival time can be obtained easily. For illustration purposes, we focus on a model that is based on the generalized lambda distribution (GLD). The GLD and many other quantile function models are defined only through their quantile functions, no closed‐form expressions are available for other equivalent functions. We also develop a Bayesian Markov Chain Monte Carlo (MCMC) method for parameter estimation. Extensive simulation studies have been conducted. Both simulation study and application results show that the proposed quantile survival models can be very useful in practice.     

Bayesian spectral analysis models for quantile regression with Dirichlet process mixtures

This paper presents a Bayesian analysis of partially linear additive models for quantile regression. We develop a semiparametric Bayesian approach to quantile regression models using a spectral representation of the nonparametric regression functions and the Dirichlet process (DP) mixture for error distribution. We also consider Bayesian variable selection procedures for both parametric and nonparametric components in a partially linear additive model structure based on the Bayesian shrinkage priors via a stochastic search algorithm. Based on the proposed Bayesian semiparametric additive quantile regression model referred to as BSAQ, the Bayesian inference is considered for estimation and model selection. For the posterior computation, we design a simple and efficient Gibbs sampler based on a location-scale mixture of exponential and normal distributions for an asymmetric Laplace distribution, which facilitates the commonly used collapsed Gibbs sampling algorithms for the DP mixture models. Additionally, we discuss the asymptotic property of the sempiparametric quantile regression model in terms of consistency of posterior distribution. Simulation studies and real data application examples illustrate the proposed method and compare it with Bayesian quantile regression methods in the literature.     

Bayesian Tobit quantile regression using g-prior distribution with ridge parameter

A Bayesian approach is proposed for coefficient estimation in the Tobit quantile regression model. The proposed approach is based on placing a g-prior distribution depends on the quantile level on the regression coefficients. The prior is generalized by introducing a ridge parameter to address important challenges that may arise with censored data, such as multicollinearity and overfitting problems. Then, a stochastic search variable selection approach is proposed for Tobit quantile regression model based on g-prior. An expression for the hyperparameter g is proposed to calibrate the modified g-prior with a ridge parameter to the corresponding g-prior. Some possible extensions of the proposed approach are discussed, including the continuous and binary responses in quantile regression. The methods are illustrated using several simulation studies and a microarray study. The simulation studies and the microarray study indicate that the proposed approach performs well.     

Estimation of Non‐Crossing Quantile Regression Curves

Quantile regression methods have been widely used in many research areas in recent years. However conventional estimation methods for quantile regression models do not guarantee that the estimated quantile curves will be non‐crossing. While there are various methods in the literature to deal with this problem, many of these methods force the model parameters to lie within a subset of the parameter space in order for the required monotonicity to be satisfied. Note that different methods may use different subspaces of the space of model parameters. This paper establishes a relationship between the monotonicity of the estimated conditional quantiles and the comonotonicity of the model parameters. We develope a novel quasi‐Bayesian method for parameter estimation which can be used to deal with both time series and independent statistical data. Simulation studies and an application to real financial returns show that the proposed method has the potential to be very useful in practice.     

Semiparametric Quantile Regression Analysis of Right‐censored and Length‐biased Failure Time Data with Partially Linear Varying Effects

Right‐censored and length‐biased failure time data arise in many fields including cross‐sectional prevalent cohort studies, and their analysis has recently attracted a great deal of attention. It is well‐known that for regression analysis of failure time data, two commonly used approaches are hazard‐based and quantile‐based procedures, and most of the existing methods are the hazard‐based ones. In this paper, we consider quantile regression analysis of right‐censored and length‐biased data and present a semiparametric varying‐coefficient partially linear model. For estimation of regression parameters, a three‐stage procedure that makes use of the inverse probability weighted technique is developed, and the asymptotic properties of the resulting estimators are established. In addition, the approach allows the dependence of the censoring variable on covariates, while most of the existing methods assume the independence between censoring variables and covariates. A simulation study is conducted and suggests that the proposed approach works well in practical situations. Also, an illustrative example is provided.     

An efficient model-free estimation of multiclass conditional probability

Conventional multiclass conditional probability estimation methods, such as Fisher's discriminate analysis and logistic regression, often require restrictive distributional model assumption. In this paper, a model-free estimation method is proposed to estimate multiclass conditional probability through a series of conditional quantile regression functions. Specifically, the conditional class probability is formulated as a difference of corresponding cumulative distribution functions, where the cumulative distribution functions can be converted from the estimated conditional quantile regression functions. The proposed estimation method is also efficient as its computation cost does not increase exponentially with the number of classes. The theoretical and numerical studies demonstrate that the proposed estimation method is highly competitive against the existing competitors, especially when the number of classes is relatively large.     

Quantile regression estimation for distortion measurement error data

We study the quantile estimation methods for the distortion measurement error data when variables are unobserved and distorted with additive errors by some unknown functions of an observable confounding variable. After calibrating the error-prone variables, we propose the quantile regression estimation procedure and composite quantile estimation procedure. Asymptotic properties of the proposed estimators are established, and we also investigate the asymptotic relative efficiency compared with the least-squares estimator. Simulation studies are conducted to evaluate the performance of the proposed methods, and a real dataset is analyzed as an illustration.     

Estimation and variable selection in single-index composite quantile regression

In this article, a new composite quantile regression estimation approach is proposed for estimating the parametric part of single-index model. We use local linear composite quantile regression (CQR) for estimating the nonparametric part of single-index model (SIM) when the error distribution is symmetrical. The weighted local linear CQR is proposed for estimating the nonparametric part of SIM when the error distribution is asymmetrical. Moreover, a new variable selection procedure is proposed for SIM. Under some regularity conditions, we establish the large sample properties of the proposed estimators. Simulation studies and a real data analysis are presented to illustrate the behavior of the proposed estimators.     

Variable screening for ultrahigh dimensional censored quantile regression

Quantile regression is a flexible approach to assessing covariate effects on failure time, which has attracted considerable interest in survival analysis. When the dimension of covariates is much larger than the sample size, feature screening and variable selection become extremely important and indispensable. In this article, we introduce a new feature screening method for ultrahigh dimensional censored quantile regression. The proposed method can work for a general class of survival models, allow for heterogeneity of data and enjoy desirable properties including the sure screening property and the ranking consistency property. Moreover, an iterative version of screening algorithm has also been proposed to accommodate more complex situations. Monte Carlo simulation studies are designed to evaluate the finite sample performance under different model settings. We also illustrate the proposed methods through an empirical analysis.     

Bayesian elastic net single index quantile regression

Single index model conditional quantile regression is proposed in order to overcome the dimensionality problem in nonparametric quantile regression. In the proposed method, the Bayesian elastic net is suggested for single index quantile regression for estimation and variables selection. The Gaussian process prior is considered for unknown link function and a Gibbs sampler algorithm is adopted for posterior inference. The results of the simulation studies and numerical example indicate that our propose method, BENSIQReg, offers substantial improvements over two existing methods, SIQReg and BSIQReg. The BENSIQReg has consistently show a good convergent property, has the least value of median of mean absolute deviations and smallest standard deviations, compared to the other two methods.     

Smoothed empirical likelihood for quantile regression models with response data missing at random

This paper studies smoothed quantile linear regression models with response data missing at random. Three smoothed quantile empirical likelihood ratios are proposed first and shown to be asymptotically Chi-squared. Then, the confidence intervals for the regression coefficients are constructed without the estimation of the asymptotic covariance. Furthermore, a class of estimators for the regression parameter is presented to derive its asymptotic distribution. Simulation studies are conducted to assess the finite sample performance. Finally, a real-world data set is analyzed to illustrated the effectiveness of the proposed methods.     

Quantile regression based on a weighted approach under semi-competing risks data

In this article, we investigate the quantile regression analysis for semi-competing risks data in which a non-terminal event may be dependently censored by a terminal event. Due to the dependent censoring, the estimation of quantile regression coefficients on the non-terminal event becomes difficult. In order to handle this problem, we assume Archimedean Copula to specify the dependence of the non-terminal event and the terminal event. Portnoy [Censored regression quantiles. J Amer Statist Assoc. 2003;98:1001–1012] considered the quantile regression model under right-censoring data. We extend his approach to construct a weight function, and then impose the weight function to estimate the quantile regression parameter for the non-terminal event under semi-competing risks data. We also prove the consistency and asymptotic properties for the proposed estimator. According to the simulation studies, the performance of our proposed method is good. We also apply our suggested approach to analyse a real data.     

Power-transformed linear regression on quantile residual life for censored competing risks data

ABSTRACT

This paper proposes a power-transformed linear quantile regression model for the residual lifetime of competing risks data. The proposed model can describe the association between any quantile of a time-to-event distribution among survivors beyond a specific time point and the covariates. Under covariate-dependent censoring, we develop an estimation procedure with two steps, including an unbiased monotone estimating equation for regression parameters and cumulative sum processes for the Box–Cox transformation parameter. The asymptotic properties of the estimators are also derived. We employ an efficient bootstrap method for the estimation of the variance–covariance matrix. The finite-sample performance of the proposed approaches are evaluated through simulation studies and a real example.     

Bayesian composite quantile regression

One advantage of quantile regression, relative to the ordinary least-square (OLS) regression, is that the quantile regression estimates are more robust against outliers and non-normal errors in the response measurements. However, the relative efficiency of the quantile regression estimator with respect to the OLS estimator can be arbitrarily small. To overcome this problem, composite quantile regression methods have been proposed in the literature which are resistant to heavy-tailed errors or outliers in the response and at the same time are more efficient than the traditional single quantile-based quantile regression method. This paper studies the composite quantile regression from a Bayesian perspective. The advantage of the Bayesian hierarchical framework is that the weight of each component in the composite model can be treated as open parameter and automatically estimated through Markov chain Monte Carlo sampling procedure. Moreover, the lasso regularization can be naturally incorporated into the model to perform variable selection. The performance of the proposed method over the single quantile-based method was demonstrated via extensive simulations and real data analysis.     

Bayesian Elastic Net Tobit Quantile Regression

In this article, the problem of parameter estimation and variable selection in the Tobit quantile regression model is considered. A Tobit quantile regression with the elastic net penalty from a Bayesian perspective is proposed. Independent gamma priors are put on the l₁ norm penalty parameters. A novel aspect of the Bayesian elastic net Tobit quantile regression is to treat the hyperparameters of the gamma priors as unknowns and let the data estimate them along with other parameters. A Bayesian Tobit quantile regression with the adaptive elastic net penalty is also proposed. The Gibbs sampling computational technique is adapted to simulate the parameters from the posterior distributions. The proposed methods are demonstrated by both simulated and real data examples.     

Bayesian bridge quantile regression

Regularization methods for simultaneous variable selection and coefficient estimation have been shown to be effective in quantile regression in improving the prediction accuracy. In this article, we propose the Bayesian bridge for variable selection and coefficient estimation in quantile regression. A simple and efficient Gibbs sampling algorithm was developed for posterior inference using a scale mixture of uniform representation of the Bayesian bridge prior. This is the first work to discuss regularized quantile regression with the bridge penalty. Both simulated and real data examples show that the proposed method often outperforms quantile regression without regularization, lasso quantile regression, and Bayesian lasso quantile regression.     

Single-index composite quantile regression

In this paper, we extend the composite quantile regression (CQR) method to a single-index model. The unknown link function is estimated by local composite quantile regression and the parametric index is estimated through the linear composite quantile. It is shown that the proposed estimators are consistent and asymptotically normal. The simulation studies and real data applications are conducted to illustrate the finite sample performance of the proposed methods.