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1.
A Bayesian discovery procedure   总被引:1,自引:0,他引:1  
Summary.  We discuss a Bayesian discovery procedure for multiple-comparison problems. We show that, under a coherent decision theoretic framework, a loss function combining true positive and false positive counts leads to a decision rule that is based on a threshold of the posterior probability of the alternative. Under a semiparametric model for the data, we show that the Bayes rule can be approximated by the optimal discovery procedure, which was recently introduced by Storey. Improving the approximation leads us to a Bayesian discovery procedure, which exploits the multiple shrinkage in clusters that are implied by the assumed non-parametric model. We compare the Bayesian discovery procedure and the optimal discovery procedure estimates in a simple simulation study and in an assessment of differential gene expression based on microarray data from tumour samples. We extend the setting of the optimal discovery procedure by discussing modifications of the loss function that lead to different single-thresholding statistics. Finally, we provide an application of the previous arguments to dependent (spatial) data.  相似文献   

2.
The Kolassa method implemented in the nQuery Advisor software has been widely used for approximating the power of the Wilcoxon–Mann–Whitney (WMW) test for ordered categorical data, in which Edgeworth approximation is used to estimate the power of an unconditional test based on the WMW U statistic. When the sample size is small or when the sizes in the two groups are unequal, Kolassa’s method may yield quite poor approximation to the power of the conditional WMW test that is commonly implemented in statistical packages. Two modifications of Kolassa’s formula are proposed and assessed by simulation studies.  相似文献   

3.
The Kim filter (KF) approximation is widely used for the likelihood calculation of dynamic linear models with Markov regime-switching parameters. However, despite its popularity, its approximation error has not yet been examined rigorously. Therefore, this study investigates the reliability of the KF approximation for maximum likelihood (ML) and Bayesian estimations. To measure the approximation error, we compare the outcomes of the KF method with those of the auxiliary particle filter (APF). The APF is a numerical method that requires a longer computing time, but its numerical error can be sufficiently minimized by increasing simulation size. According to our extensive simulation and empirical studies, the likelihood values obtained from the KF approximation are practically identical to those of the APF. Furthermore, we show that the KF method is reliable, particularly when regimes are persistent and sample size is small. From the Bayesian perspective, we show that the KF method improves the efficiency of posterior simulation. This study contributes to the literature by providing evidence to justify the use of the KF method in both ML and Bayesian estimations.  相似文献   

4.
The integration of different data sources is a widely discussed topic among both the researchers and the Official Statistics. Integrating data helps to contain costs and time required by new data collections. The non-parametric micro Statistical Matching (SM) allows to integrate ‘live’ data resorting only to the observed information, potentially avoiding the misspecification bias and speeding the computational effort. Despite these pros, the assessment of the integration goodness when we use this method is not robust. Moreover, several applications comply with some commonly accepted practices which recommend e.g. to use the biggest data set as donor. We propose a validation strategy to assess the integration goodness. We apply it to investigate these practices and to explore how different combinations of the SM techniques and distance functions perform in terms of the reliability of the synthetic (complete) data set generated. The validation strategy takes advantage of the relation existing among the variables pre-and-post the integration. The results show that ‘the biggest, the best’ rule must not be considered mandatory anymore. Indeed, the integration goodness increases in relation to the variability of the matching variables rather than with respect to the dimensionality ratio between the recipient and the donor data set.  相似文献   

5.
The accuracy of a normal approximation to the exact conditional power function of the Manic!-Haenszcl one degree ni freedom chi-squared procedure is nnesugaied The maximum approximation error over the parameter space is studied for designs with equal numbers of cases and controls within and across strata. An empirical rule is provided for the estimation of the maximum error, the rule performs well over a range of design constants of importance in stratified case-control studies.  相似文献   

6.
This paper considers the statistical reliability on discrete failure data and the selection of the best geometric distribution having the smallest failure probability from among several competitors. Using the Bayesian approach a Bayes selection rule based on type-I censored data is derived and its associated monotonicity is also obtained. An early selection rule which allows us to make a selection possible earlier than the censoring time of the life testing experiment is proposed. This early selection rule can be shown to be equivalent to the Bayes selection rule. An illustrative example is given to demonstrate the use and the performance of the early selection rule.  相似文献   

7.
In this paper, we consider the estimation reliability in multicomponent stress-strength (MSS) model when both the stress and strengths are drawn from Topp-Leone (TL) distribution. The maximum likelihood (ML) and Bayesian methods are used in the estimation procedure. Bayesian estimates are obtained by using Lindley’s approximation and Gibbs sampling methods, since they cannot be obtained in explicit form in the context of TL. The asymptotic confidence intervals are constructed based on the ML estimators. The Bayesian credible intervals are also constructed using Gibbs sampling. The reliability estimates are compared via an extensive Monte-Carlo simulation study. Finally, a real data set is analysed for illustrative purposes.  相似文献   

8.
Progressively censored data from a classical Pareto distribution are to be used to make inferences about its shape and precision parameters and the reliability function. An approximation form due to Tierney and Kadane (1986) is used for obtaining the Bayes estimates. Bayesian prediction of further observations from this distribution is also considered. When the Bayesian approach is concerned, conjugate priors for either the one or the two parameters cases are considered. To illustrate the given procedures, a numerical example and a simulation study are given.  相似文献   

9.
There have been numerous tests proposed to determine whether or not the exponential model is suitable for a given data set. In this article, we propose a new test statistic based on spacings to test whether the general progressive Type-II censored samples are from exponential distribution. The null distribution of the test statistic is discussed and it could be approximated by the standard normal distribution. Meanwhile, we propose an approximate method for calculating the expectation and variance of samples under null hypothesis and corresponding power function is also given. Then, a simulation study is conducted. We calculate the approximation of the power based on normality and compare the results with those obtained by Monte Carlo simulation under different alternatives with distinct types of hazard function. Results of simulation study disclose that the power properties of this statistic by using Monte Carlo simulation are better for the alternatives with monotone increasing hazard function, and otherwise, normal approximation simulation results are relatively better. Finally, two illustrative examples are presented.  相似文献   

10.
Exponential distribution has an extensive application in reliability. Introducing shape parameter to this distribution have produced various distribution functions. In their study in 2009, Gupta and Kundu brought another distribution function using Azzalini's method, which is applicable in reliability and named as weighted exponential (WE) distribution. The parameters of this distribution function have been recently estimated by the above two authors in classical statistics. In this paper, Bayesian estimates of the parameters are derived. To achieve this purpose we use Lindley's approximation method for the integrals that cannot be solved in closed form. Furthermore, a Gibbs sampling procedure is used to draw Markov chain Monte Carlo samples from the posterior distribution indirectly and then the Bayes estimates of parameters are derived. The estimation of reliability and hazard functions are also discussed. At the end of the paper, some comparisons between classical and Bayesian estimation methods are studied by using Monte Carlo simulation study. The simulation study incorporates complete and Type-II censored samples.  相似文献   

11.
The Gompertz distribution has been used as a growth model, especially in epidemiological and biomedical studies. Based on Type I and II censored samples from a heterogeneous population that can be represented by a finite mixture of two-component Gompertz lifetime model, the maximum likelihood and Bayes estimates of the parameters, reliability and hazard rate functions are obtained. An approximation form due to Lindley (1980) is used in obtaining the corresponding Bayes estimates. The maximum likelihood and Bayes estimates are comparedvia a Monte Carlo simulation study.  相似文献   

12.
Parametric incomplete data models defined by ordinary differential equations (ODEs) are widely used in biostatistics to describe biological processes accurately. Their parameters are estimated on approximate models, whose regression functions are evaluated by a numerical integration method. Accurate and efficient estimations of these parameters are critical issues. This paper proposes parameter estimation methods involving either a stochastic approximation EM algorithm (SAEM) in the maximum likelihood estimation, or a Gibbs sampler in the Bayesian approach. Both algorithms involve the simulation of non-observed data with conditional distributions using Hastings–Metropolis (H–M) algorithms. A modified H–M algorithm, including an original local linearization scheme to solve the ODEs, is proposed to reduce the computational time significantly. The convergence on the approximate model of all these algorithms is proved. The errors induced by the numerical solving method on the conditional distribution, the likelihood and the posterior distribution are bounded. The Bayesian and maximum likelihood estimation methods are illustrated on a simulated pharmacokinetic nonlinear mixed-effects model defined by an ODE. Simulation results illustrate the ability of these algorithms to provide accurate estimates.  相似文献   

13.
对半参数变系数回归模型,构造了新的空间相关性检验统计量,利用三阶矩 逼近方法导出了其检验 值的近似计算公式,蒙特卡罗模拟结果表明该统计量在检测空间相关性方面具有较高的准确性和可靠性。同时考察了误差项服从不同分布时的检验功效,体现出该检验方法的稳健性。进一步,我们还给出了检验统计量的Bootstrap方法以及检验水平的模拟效果。  相似文献   

14.
We explore the possibility of approximating the Ferguson-Dirichlet prior and the distributions of its random functionals through the simulation of random probability measures. The proposed procedure is based on the constructive definition illustrated in Sethuraman (1994) in conjunction with the use of a random stopping rule. This allows us to set in advance the closeness to the distributions of interest. The distribution of the stopping rule is derived, and the practicability of the simulating procedure is discussed. Sufficient conditions for convergence of random functionals are provided. The numerical applications provided just sketch the idea of the variety of nonparametric procedures that can be easily and safely implemented in a Bayesian setting.  相似文献   

15.
We consider a challenging problem of testing any possible association between a response variable and a set of predictors, when the dimensionality of predictors is much greater than the number of observations. In the context of generalized linear models, a new approach is proposed for testing against high-dimensional alternatives. Our method uses soft-thresholding to suppress stochastic noise and applies the independence rule to borrow strength across the predictors. Moreover, the method can provide a ranked predictor list and automatically select “important” features to retain in the test statistic. We compare the performance of this method with some competing approaches via real data and simulation studies, demonstrating that our method maintains relatively higher power against a wide family of alternatives.  相似文献   

16.
Numerical approximations are often used to implement the Bayesian paradigm in analytically intractable parametric models. We focus on embedded integration rules which are an attractive numerical integration tool and present theoretical results which justify their use in a Bayesian integration strategy.  相似文献   

17.
In the present work, whenever the response variables are binary, we frame an adaptive allocation rule for a two-treatment two-period crossover design in the presence of possible carry-over effects. The proposed rule is a combination of the play-the-winner and randomized play-the-winner rules. We study various properties of the proposed rule through asymptotics and simulations. Some related inferential problems are also considered. The proposed procedure is compared with some possible competitor.  相似文献   

18.
文章介绍了泰勒规则,即在产生、内涵、发展的基础上,利用Lawrence模型将汇率因素引入,构建了开放经济条件下的前瞻性泰勒规则。实证结果表明:泰勒规则能够为中国货币政策提供一个很好的参照系;相对于物价稳定目标,央行更关注经济增长;将微观主体的预期和汇率因素引入到货币政策时,央行对利率的敏感性增强;继续推动利率和汇率体制改革能更有效地提高泰勒规则的解释力;“前瞻性泰勒规则”能提高中国货币政策的透明度。  相似文献   

19.
Renewal-type equations are frequently encountered in the study of reliability, warranty analysis, replacement and maintenance policies, and inventory control. Renewal equations usually do not have analytical solutions, and hence, bounds or approximations are very useful. In this article, analytical bounds are studied based on a simple iterative procedure which provides some analytical results and nice convergence properties when the number of iteration increases. Bounds and approximations are also investigated for a recursive algorithm for numerical computation. In addition, some interesting monotonicity properties are introduced and discussed. The approximation error, which is important for determining the stopping rule of the iterative procedure and the numerical algorithm, is also studied.  相似文献   

20.
ABSTRACT

In this paper, the stress-strength reliability, R, is estimated in type II censored samples from Pareto distributions. The classical inference includes obtaining the maximum likelihood estimator, an exact confidence interval, and the confidence intervals based on Wald and signed log-likelihood ratio statistics. Bayesian inference includes obtaining Bayes estimator, equi-tailed credible interval, and highest posterior density (HPD) interval given both informative and non-informative prior distributions. Bayes estimator of R is obtained using four methods: Lindley's approximation, Tierney-Kadane method, Monte Carlo integration, and MCMC. Also, we compare the proposed methods by simulation study and provide a real example to illustrate them.  相似文献   

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