Impact of metabolic status on the association of serum vitamin D with hypogonadism and lower urinary tract symptoms/benign prostatic hyperplasia

Objective: The objective of this study is to investigate the impact of metabolic status on associations of serum vitamin D with hypogonadism and lower urinary tract symptoms (LUTS)/benign prostatic hyperplasia (BPH).

Patients and methods: A total of 612 men underwent physical examination, biochemical/hormonal blood testing, and transrectal prostate ultrasound. Moreover, the subjects filled out standard questionnaires for identification and grading of LUTS and hypogonadism symptoms. Parameters were statistically compared with independent t-tests and correlation analyses.

Results: Vitamin D levels positively correlated with total testosterone (TT) but not with prostate volume or International Prostate Symptom Score (IPSS). Patients with metabolic syndrome had significantly lower vitamin D levels, which were not correlated with TT, prostate volume, or IPSS. However, vitamin D was positively correlated with TT, and negatively correlated with prostate volume and quality-of-life IPSS in subjects without metabolic syndrome.

Conclusion: The clinical usefulness of vitamin D for treatment of hypogonadism or LUTS/BPH varies according to metabolic status.     

Book reviews

The Political Sociology of Florian Znaniecki and Contemporary Politics (in Polish), Olgierd Sochacki (Ed.) Wydawnictwo Gdanskie, The Scientific Society of Gdansk, 1996

Why Read. Internal Space and the Social Function of Literature: An Investigation with. Psychoanalysts and Psychology Students, Graziella Pagliano (Ed.) Bonanno Editore, 1994

Voix Littéraires de Femmes

Cuadernos sobre Vico, Nos 5–6, José M. Sevilla et al. 1995–96

Studi in memoria di Ernesto Grassi Proceedings of the International Conference in Memory of Ernesto Grassi (Ischia, 4–6 October 1993), Emilio Hidalgo‐Serna and Massimo Marassi (Eds), Napoli, La Città del Sole, 1996

Naples Istituto Italiano per gli Studi Fiosofici, La Gittà del Sole, Napoli, 1996

Family, Women and Employment in Central‐Eastern Europe, Barbara Lobodzinska (Ed.) Greenwood Press, 1995     

Effects of resistance training on liver structure and function of aged rats

The aging process may cause negative physiological changes. However, exercises as resistance training (RT) have been considered an important intervention to attenuate these changes. Additionally, liver plays an important role in blood glucose homeostasis in exercise.

Aim: This study aimed to analyze the effects of RT on the liver components of aged animals.

Methods: Male Wistar rats were divided into two groups: 24 months’ group (CONTROL); and group submitted to a progressive RT protocol for 16 weeks (EXERCISE). Both groups were sacrificed at 24 months.

Results: We observed a decrease in blood flow due to the practice of resistance exercises. Besides, our results showed that hepatic tissue plays an important role in glycemic homeostasis during RT. In addition, RT increased mitogen capacity of hepatocytes.

Conclusions: Our study showed many implications for the knowledge about the effects of strength training on old animals’ liver.     

Housing in Old Age: Dynamical Interactions Between Neighborhood Attachment,Neighbor Annoyance,and Residential Satisfaction

Objective: Residential satisfaction and neighborhood quality play major roles in aging well. However, longitudinal research about the interplay between such factors is still sparse. Our 1-year study examined whether change in residential satisfaction was associated with change in two indicators of neighborhood quality: neighborhood attachment and neighbor annoyance.

Methods: Findings come from a longitudinal study with 85 community-dwelling German older adults (age range: 60 to 92 years). Participants filled out questionnaires at two measurements that were 1 year apart. The interplay between residential satisfaction and neighborhood was explored using a cross-path model.

Results: Higher levels of residential satisfaction predicted enhanced attachment and reduced annoyance over time. Moreover, attachment predicted positive change in residential satisfaction over the course of 1 year.

Conclusion: Results suggest that older adults may apply adaptive behaviors and strategies to optimize their neighborly experiences. Such findings have implications for improving residential satisfaction in community-dwelling older adults.     

The Impact of the Physical Home Environment for Family Carers of People with Dementia: A Qualitative Study

Background: The majority of people with dementia are cared for by their families at home. This study aimed to elicit family carers' perceptions on home environmental aspects and strategies with the view to identify barriers and facilitators when caring for a person with dementia at home.

Design and methods: Thirteen co-resident family carers were engaged in semi-structured in-depth walking interviews. Interviews were recorded, transcribed and analysed using thematic analysis.

Results: Home environments can pose a number of challenges and opportunities. Aspects of the architectural and interior environment (e.g. size, condition, layout and accessibility, familiarity) are perceived as important (Theme 1) as well as a plethora of environmental strategies that encourage independence and comfort at home (Theme 2). Carers' scepticism, timing, costs, property characteristics and mistrust to services are some barriers to implementing environmental strategies (Theme 3).

Conclusions: Carers improvised solutions via trial and error and need further education on strategies to create an enabling and comfortable home environment.     

Attitudes and knowledge of social work students towards sexuality in later life

Background: Sexuality in later life may be compromised by restrictive attitudes, and lack of knowledge among professionals. This study examined social work students’ attitudes and knowledge towards sexuality and sexual expression in later life and investigated associated factors.

Method: Undergraduate social work students from Israel (n = 375) completed the Attitudes and Knowledge towards Older Adult’s Sexuality Scale and questionnaires regarding contacts and exposure to older adults, prior sexual education and sociodemographic.

Results: Attitudes and knowledge were correlated. First year students were the most conservative and demonstrated the least knowledge. No differences were found between men and women regarding attitude. However, men and married students had greater knowledge regarding older adults’ sexuality than women or non-married students did. Increased religious observance predicted more conservative attitudes. Age predicted more permissive attitudes and greater knowledge about sexuality in later life. A mediating process examined, suggested knowledge is a mediator variable between age and attitudes towards older adults’ sexuality.

Conclusion: As the population in Israel and in Western countries ages, it is important to examine the knowledge and attitudes of social work students regarding older adults’ sexuality and to develop educational and interventional programs aimed at increasing awareness, knowledge, and positive attitudes in this area.     

Feasibility of intervention in elder self-neglecters: Setting the stage for future research

Objectives: Interventions are critical to improving clinical outcomes in elder self-neglecters. This study assessed feasibility of a randomized controlled trial of oral vitamin D in Adult Protective Services-substantiated self-neglect clients ≥65 years.

Methods: Participants were directly observed to consume ergocalciferol 50,000 IU (treatment) or ergocalciferol 400 IU (control), once a month, for 10 months. For months 6–10, half the control group randomly crossed into the treatment group (crossover). Intervention feasibility was measured by number of potential participants who agreed to participate and by retention rates during the study.

Results: Ninety-four referrals were received and 59 (63%) agreed to participate. Forty-nine participants were enrolled after prescreening and 35 completed the two-phase trial for a 72% retention rate. The participants’ average age was 75.2 ± 6.8 years, mainly female (59%), African-American (47%), and living alone (41%).

Discussion: Despite assumptions that self-neglecters are resistant to care, we have successfully conducted the first clinical intervention in this vulnerable population.     

Factors Influencing Family-Member Perception of “Homelikeness” in Long-Term Care Homes

Background: A number of long-term care homes in Nova Scotia, Canada, have been built or redesigned with new models of care with expanded care aide scope of practice and neighborhood-style layouts. Our objective was to examine what physical characteristics (bed size, owner-operator), model of care, and relational (family–staff relationship, perceived staff–resident relationship) factors were associated with increased family-member perception of homelikeness in long-term care homes.

Methods: We analyzed surveys collected from 273 family members from 23 long-term care homes in Nova Scotia, Canada. We conducted a multivariate linear regression to assess variables associated with increased family-member perception of homelikeness.

Results: We found that relationships between family and staff, perceived resident-to-resident relationships, and family involvement in decision making were positively associated with increased family perception of homelikeness. We found no significant associations between model of care or physical characteristics and increased family perception of homelikeness.

Conclusion: Relationships among family members, residents, and staff are integral to family members feeling at home in their loved one's long-term care home. Feeling at home in long-term care is largely related to family-member perception of meaningful social interactions between family and staff, and between residents.     

Reference database of hematological parameters for growing and aging rats

The normal hematological values in various phases of the rat life provide a valuable guide to researchers and could be useful for experimental works. However, database information available on the literature are incomplete. Aim: This study aimed to present normal hematological parameters of young and aged rats.

Methods: Male and female rats were distributed into seven experimental groups with 1, 2, 3, 6, 12, 18, and 24 months of age. Blood samples taken from the tails were analyzed. Normal hematological values were determined for each age group.

Results: Rats showed a progressive weight gain with advancing age, predominantly after 3 months of life. With advancing age, differences were found on hematological parameters: some of them showed a progressive rise with age and others did not. Hemoglobin levels and hematocrit did not change while the number of circulating red blood cells suffered slight increase.

Conclusion: The present study determined the normal values for absolute and relative hematological parameters in Wistar rats from 2 to 24 months for male and female rats. The results can be used in studies of effects of aging, feeding, and medications on growing and aging rats.     

Recantation of Sexual Abuse Disclosure Among Child Victims: Accommodation Syndrome

Background: Disclosing the sexual abuse may be related on many individual and/or environmental factors in all age groups. The sociocultural context is the most influential factor of the disclosing process especially for those living in patriarchal cultural values. This study compares the impacts of sexual abuse and other sociodemographic variables between recanting and non-recanting victimized groups in Adana city from Turkey.

Methods: The samples attending our department were divided into two groups: group 1 comprised victims who recanted their first abuse disclosure, and group 2 comprised victims who insisted on the veracity of their first report at further evaluations. The characteristics of the child, family, and abuser were compared between recanting victims and non-recanting victims by retrospective data.

Results: Each group included 27 children, for a total of 54 subjects. All adverse social reactions after the sexual abuse, including keeping secrets and a repressive family attitude, were higher among group 1 victims than group 2 victims (p < 0.0001).

Conclusions: Although they are victimized by protecting family integrity, victims may show a tendency to keep secrets and to not immediately disclose an abuse event.     

Association of general and abdominal obesity with age,endocrine and metabolic factors in Asian men

Objective: This study made use of the percent abdominal fat to define abdominal obesity (AbO) and examined the differential associations of general obesity (GOb) and AbO with age, metabolic and endocrine factors.

Methods: Metabolic, endocrine and anthropometric factors and body composition were measured in 481 Asian men.

Results: A DEXA-derived ≥25% abdominal fat (PAbdF) was used to define men with AbO. Age was directly associated with PAbdF and percent total body fat (PBF). Exercise intensity was negatively associated with PBF. Both PBF and PAbdF were associated with HDL and LDL, but have opposite correlation with triglyceride. Furthermore, both PBF and PAbdF were associated with the number of metabolic syndrome (MetS) risk factors. Men with GOb had lower levels of percent lean mass (PLM), testosterone and bioavailable testosterone, and higher insulin and glucose levels. Men with AbO had lower arm and leg fat, higher insulin levels and triglycerides.

Conclusions: Men with GOb and AbO had different pattern of body composition. Age may be a contributory factor in AbO and a sedentary lifestyle may contribute to GOb. Both GOb and AbO are associated with an increased risk of MetS, with GOb more predispose to risk of diabetes, while AbO more at risk for cardiovascular diseases.     

Book reviews

Women and phenomenology—a survey of the literature

Élites discriminadas (sobre el poder de las mujeres) María Antonia García de Leòn Santafé de Bogotà, Editorial Anthropos, 1994, 254 pp.

G. Ferrero, El Poder. Los genios invisibles de la Ciudad     

Inverse association of testosterone and sex hormone binding globulin levels with leukocyte count in middle-aged and elderly men

Objective: The inverse associations of testosterone and sex hormone-binding globulin (SHBG) levels with cardiometabolic diseases are well established and are increasingly viewed as inflammatory diseases. This study aimed to examine the associations of testosterone and SHBG levels with leukocyte count in 451 Korean men aged ≥50 years.

Methods: Serum testosterone and SHBG levels were categorized into tertiles. High leukocyte count was defined as ≥7340 cells/μl, which corresponded to the 75th percentile of the current sample. The odds ratios (ORs) and 95% confidence intervals (95% CIs) for high leukocyte count were calculated across testosterone and SHBG tertiles using multiple logistic regression analysis.

Results: The mean leukocyte counts significantly decreased with increasing testosterone and SHBG tertiles. The ORs (95% CIs) of high leukocyte count for the first tertile of testosterone and SHBG were 3.27 (1.34–7.95) and 2.38 (1.05–5.96), respectively, compared with the referent third tertile, after adjusting for age, smoking status, alcohol drinking, regular exercise, body mass index, blood pressure, fasting plasma glucose, triglyceride, and high-density lipoprotein (HDL) cholesterol level.

Conclusion: We found inversely graded associations of low testosterone and SHBG levels with leukocyte count. These findings suggest that low testosterone and SHBG levels may be interpreted as a state of low-grade inflammation.     

Effects of testosterone administration on liver structure and function in aging rats

Aging males have a decrease in testosterone levels, by which the testosterone treatment may influence in a negatively fashion the liver.

Aim: This study aimed to analyze the effects of aging with or without testosterone administration on the liver components of animals.

Methods: Wistar rats were divided into three groups: 20 months’ group (G20), 24 months’ group (G24), group treated with testosterone for 16 weeks (GT). All groups were sacrificed at 24 months except for G20 that was sacrificed at 20 months.

Results: Aging and testosterone treatment alters the body weight (BW), liver weight (LW) and relative liver weight. Besides, testosterone increased the mitogen capacity of hepatocytes. Nonetheless, we reinforce the negative effects of testosterone on old animals’ liver as chronic hepatic congestion and/or cholestasis. In addition, we observed that testosterone plays an important role on hepatic glycogen stores.

Conclusions: Our study showed many implications for the knowledge about the effects of aging with or without testosterone administration on old animals’ liver.     

Book reviews

The World of the Passions in the Utopian Imaginary (Symposium on Utopia) Bruna Consarelli and Nicola Di Penta (eds) Giuffrè Editore, Milano, 1997, pp. 405

Giambattista Vico in the Naples and Seville Centres     

Between memory and history A word about intercultural education

The author briefly describes the history of the intercultural approach at the Council of Europe, which is largely responsible for the promotion of this concept, as well as for the development of a network of thought and action throughout Europe.

The article stresses the fact that, contrary to what some researchers may lead us to believe, the intercultural concept has always included the aspects of interaction, of reciprocity, of dialogue and of solidarity. In addition, pedagogical and sociological practice, where thought and action are closely linked have influenced its development.

We can now state that there are more and more places where intercultural thought and action are being pursued. Movements promoting international education, global education, civic European education, Human Rights education, etc., have different backgrounds, but their current prospects are converging. The expression ‘Human Rights education’ is often used in a generic way. However, Human Rights education that wishes to transcend ethnocentric behaviour needs to be intercultural.

     

Examining the effect of the computer-based educational package on quality of life and severity of hypogonadism symptoms in males

Objective: The objective of this study was to determine the effect of the computer-based educational package on men’s QoL and the severity of their hypogonadism symptoms.

Methods: A quasi-experimental study was conducted on 80 male employees. The data collection tool included the ‘Aging Male Symptoms’ (AMS) and ‘Short Form-36’ (SF36) questionnaires. Four sessions were held for the intervention group over a period of 4 weeks. Two months after training, QoL and the severity of hypogonadism symptoms were measured in both the intervention and control groups. The data were analyzed with SPSS 22 software and statistical tests, such as χ², independent t-test, Fisher’s exact test, and paired t-tests.

Results: Significant statistical changes were observed in the intervention group before and 2 months after the training in the QoL score in the overall dimensions of physical–psychological health and all its domains except for three domains of emotional role, social function, and pain. Furthermore, the paired t-tests showed significant differences between 2 months before and after the training in all the domains and the overall hypogonadism score in the intervention group.

Conclusions: Based on our findings, the computer-based educational package has a positive effect on QoL and reduction of hypogonadism symptoms.     

Prostate-specific antigen decline pattern in advanced prostate cancer receiving androgen deprivation therapy and relationship with prostate-specific antigen progression

Introduction: The aim of this study is to evaluate prostate-specific antigen decline pattern including prostate-specific antigen kinetics following androgen deprivation therapy on prostate-specific antigen progression in the patients with advanced prostate cancer.

Materials and methods: Ninety-seven advanced prostate cancer patients receiving maximum androgen deprivation therapy were enrolled in case–control study. Baseline prostate-specific antigen, Gleason Score, bone metastase, nadir prostate-specific antigen, time to nadir prostate-specific antigen, declining slope to nadir prostate-specific antigen, estimated baseline prostate-specific antigen half-time, current prostate-specific antigen, post-nadir prostate-specific antigen time, estimated prostate-specific antigen, estimated decline of baseline prostate-specific antigen as quantitative, and ratio were recorded and calculated.

Results: The ratio of prostate-specific antigen progression was significantly lower at the patients who had slower declining slope to prostate-specific antigen, longer time to nadir prostate-specific antigen, and lower estimated decline ratio of baseline prostate-specific antigen (p: .016, p: .020, and p: .026, respectively).

Conclusions: The shorter time to nadir prostate-specific antigen following androgen deprivation therapy, faster declining slope to nadir prostate-specific antigen and higher estimated decline ratio of baseline prostate-specific antigen are associated with higher risk of disease progression in patients with hormone-sensitive prostate cancer.     

Book Reviews

Welfare States in Transition. National Adaptations in Global Economies. Edited by Gösta Esping-Andersen. London, Sage, 1996. 276pp., ISBN 0–7619–5048–6, £13.95.

Social Protection and the European Economic and Monetary Union. Edited by Jozef Pacolet. Aldetshot, Avebury, 1996. 305 pp., ISBN 1–8562–581–2, £40.

Valuazione e sapere sociologico (Evaluation and Sociological Knowledge). Edited by G. Bertin. Milan, Franco Angeli, 1996. 299pp., L. 38.000.

I bisogni dimenticati. Rapporto 1996 su emarginazione ed esclusione sociale (Report on Social Marginalization and Exclusion). Caritas Italiana—Fondazione E. Zancan. Milan, Feltrinelli, 1997. 292pp., L. 30.000.

Social Theory, Social Change and Social Work. Edited by Nigel Parton. London, Routledge, 1996. 238pp., ISBN 0–415–12698–3, £13.99.

Lena Dominelli: Sociology for Social Work. Basingstoke, Macmillan, 1997. ISBN 0–333–61521–2, £13.99.

Simon Goodwin: Comparative Mental Health Policy: From Institutional to Community Care. London, Sage. 183pp. ISBN 0–8039–7729–8, £13.99.

Anthony Colombo: Understanding Mentally Disordered Offenders. Aldershot, Ashgate, 1997. 226pp. ISBN 1–85972–689–5. £37.50.

Critical Approaches to Ageing and Later Life.

Edited by Anne Jamieson, Sarah Harper and Christina Victor. Buckingham, Open University Press, 1977. 195pp., ISBN 0–335–19725–6. £14.99.

Education and Fascism. Political Identity and Social Education in Nazi Germany. Edited by H. Sünker and H.-U. Otto. London, Falmer Press, 1997. 180pp., ISBN 0–7507–05919-X, £14.95.