Asymptotic relative efficiency of wald tests in measurement error models

In this paper, asymptotic relative efficiency (ARE) of Wald tests for the Tweedie class of models with log-linear mean, is considered when the aux¬iliary variable is measured with error. Wald test statistics based on the naive maximum likelihood estimator and on a consistent estimator which is obtained by using Nakarnura's (1990) corrected score function approach are defined. As shown analytically, the Wald statistics based on the naive and corrected score function estimators are asymptotically equivalents in terms of ARE. On the other hand, the asymptotic relative efficiency of the naive and corrected Wald statistic with respect to the Wald statistic based on the true covariate equals to the square of the correlation between the unobserved and the observed co-variate. A small scale numerical Monte Carlo study and an example illustrate the small sample size situation.     

Exact unconditional testing procedures for comparing two independent Poisson rates

We consider seven exact unconditional testing procedures for comparing adjusted incidence rates between two groups from a Poisson process. Exact tests are always preferable due to the guarantee of test size in small to medium sample settings. Han [Comparing two independent incidence rates using conditional and unconditional exact tests. Pharm Stat. 2008;7(3):195–201] compared the performance of partial maximization p-values based on the Wald test statistic, the likelihood ratio test statistic, the score test statistic, and the conditional p-value. These four testing procedures do not perform consistently, as the results depend on the choice of test statistics for general alternatives. We consider the approach based on estimation and partial maximization, and compare these to the ones studied by Han (2008) for testing superiority. The procedures are compared with regard to the actual type I error rate and power under various conditions. An example from a biomedical research study is provided to illustrate the testing procedures. The approach based on partial maximization using the score test is recommended due to the comparable performance and computational advantage in large sample settings. Additionally, the approach based on estimation and partial maximization performs consistently for all the three test statistics, and is also recommended for use in practice.     

Hypothesis Testing in Functional Comparative Calibration Models

The purpose of this article is to investigate hypothesis testing in functional comparative calibration models. Wald type statistics are considered which are asymptotically distributed according to the chi-square distribution. The statistics are based on maximum likelihood, corrected score approach, and method of moment estimators of the model parameters, which are shown to be consistent and asymptotically normally distributed. Results of analytical and simulation studies seem to indicate that the Wald statistics based on the method of moment estimators and the corrected score estimators are, as expected, less efficient than the Wald type statistic based on the maximum likelihood estimators for small n. Wald statistic based on moment estimators are simpler to compute than the other Wald statistics tests and their performance improves significantly as n increases. Comparisons with an alternative F statistics proposed in the literature are also reported.     

Likelihood-based tests in zero-inflated power series models

We address the issue of performing testing inference in the class of zero-inflated power series models. These models provide a straightforward way of modelling count data and have been widely used in practical situations. The likelihood ratio, Wald and score statistics provide the basis for testing the parameter of inflation of zeros in this class of models. In this paper, in addition to the well-known test statistics, we also consider the recently proposed gradient statistic. We conduct Monte Carlo simulation experiments to evaluate the finite-sample performance of these tests for testing the parameter of inflation of zeros. The numerical results show that the new gradient test we propose is more reliable in finite samples than the usual likelihood ratio, Wald and score tests. An empirical application to real data is considered for illustrative purposes.     

Wald,LM and LR test statistics of linear hypothese in a strutural equation model

For the linear hypothesis in a strucural equation model, the properties of test statistics based on the two stage least squares estimator (2SLSE) have been examined since these test statistics are easily derived in the instrumental variable estimation framework. Savin (1976) has shown that inequalities exist among the test statistics for the linear hypothesis, but it is well known that there is no systematic inequality among these statistics based on 2SLSE for the linear hypothesis in a structural equation model. Morimune and Oya (1994) derived the constrained limited information maximum likelihood estimator (LIMLE) subject to general linear constraints on the coefficients of the structural equation, as well as Wald, LM and Lr Test statistics for the adequacy of the linear constraints.

In this paper, we derive the inequalities among these three test statistics based on LIMLE and the local power functions based on Limle and 2SLSE to show that there is no test statistic which is uniformly most powerful, and the LR test statistic based on LIMLE is locally unbised and the other test statistics are not. Monte Carlo simulations are used to examine the actual sizes of these test statistics and some numerical examples of the power differences among these test statistics are given. It is found that the actual sizes of these test statistics are greater than the nominal sizes, the differences between the actual and nominal sizes of Wald test statistics are generally the greatest, those of LM test statistics are the smallest, and the power functions depend on the correlations between the endogenous explanatory variables and the error term of the structural equation, the asymptotic variance of estimator of coefficients of the structural equation and the number of restrictions imposed on the coefficients.     

Which Wald statistic? Choosing a parameterization of the Wald statistic to maximize power in k-sample generalized estimating equations

The Wald statistic is known to vary under reparameterization. This raises the question: which parameterization should be chosen, in order to optimize power of the Wald statistic? We specifically consider k-sample tests of generalized linear models (GLMs) and generalized estimating equations (GEEs) in which the alternative hypothesis contains only two parameters. An example is presented in which such an alternative hypothesis is of interest. Amongst a general class of parameterizations, we find the parameterization that maximizes power via analysis of the non-centrality parameter, and show how the effect on power of reparameterization depends on sampling design and the differences in variance across samples. There is no single parameterization with optimal power across all alternatives. The Wald statistic commonly used under the canonical parameterization is optimal in some instances but it performs very poorly in others. We demonstrate results by example and by simulation, and describe their implications for likelihood ratio statistics and score statistics. We conclude that due to poor power properties, the routine use of score statistics and Wald statistics under the canonical parameterization for GEEs is a questionable practice.     

Wald,LM and LR test statistics of linear hypothese in a strutural equation model

For the linear hypothesis in a strucural equation model, the properties of test statistics based on the two stage least squares estimator (2SLSE) have been examined since these test statistics are easily derived in the instrumental variable estimation framework. Savin (1976) has shown that inequalities exist among the test statistics for the linear hypothesis, but it is well known that there is no systematic inequality among these statistics based on 2SLSE for the linear hypothesis in a structural equation model. Morimune and Oya (1994) derived the constrained limited information maximum likelihood estimator (LIMLE) subject to general linear constraints on the coefficients of the structural equation, as well as Wald, LM and Lr Test statistics for the adequacy of the linear constraints.

In this paper, we derive the inequalities among these three test statistics based on LIMLE and the local power functions based on Limle and 2SLSE to show that there is no test statistic which is uniformly most powerful, and the LR test statistic based on LIMLE is locally unbised and the other test statistics are not. Monte Carlo simulations are used to examine the actual sizes of these test statistics and some numerical examples of the power differences among these test statistics are given. It is found that the actual sizes of these test statistics are greater than the nominal sizes, the differences between the actual and nominal sizes of Wald test statistics are generally the greatest, those of LM test statistics are the smallest, and the power functions depend on the correlations between the endogenous explanatory variables and the error term of the structural equation, the asymptotic variance of estimator of coefficients of the structural equation and the number of restrictions imposed on the coefficients.     

Likelihood Ratio Tests for Fixed Model Terms using Residual Maximum Likelihood

Likelihood ratio tests for fixed model terms are proposed for the analysis of linear mixed models when using residual maximum likelihood estimation. Bartlett-type adjustments, using an approximate decomposition of the data, are developed for the test statistics. A simulation study is used to compare properties of the test statistics proposed, with or without adjustment, with a Wald test. A proposed test statistic constructed by dropping fixed terms from the full fixed model is shown to give a better approximation to the asymptotic χ²-distribution than the Wald test for small data sets. Bartlett adjustment is shown to improve the χ²-approximation for the proposed tests substantially.     

Confidence intervals for the difference of marginal probabilities in clustered matched-pair binary data

Although there are several available test statistics to assess the difference of marginal probabilities in clustered matched‐pair binary data, associated confidence intervals (CIs) are not readily available. Herein, the construction of corresponding CIs is proposed, and the performance of each CI is investigated. The results from Monte Carlo simulation study indicate that the proposed CIs perform well in maintaining the nominal coverage probability: for small to medium numbers of clusters, the intracluster correlation coefficient‐adjusted McNemar statistic and its associated Wald or Score CIs are preferred; however, this statistic becomes conservative when the number of clusters is larger so that alternative statistics and their associated CIs are preferred. In practice, a combination of the intracluster correlation coefficient‐adjusted McNemar statistic with an alternative statistic is recommended. To illustrate the practical application, a real clustered matched‐pair collection of data is used to illustrate testing the difference of marginal probabilities and constructing the associated CIs. Copyright © 2012 John Wiley & Sons, Ltd.     

Rényi statistics for testing composite hypotheses in general exponential models

We introduce a family of Rényi statistics of orders r?∈?R for testing composite hypotheses in general exponential models, as alternatives to the previously considered generalized likelihood ratio (GLR) statistic and generalized Wald statistic. If appropriately normalized exponential models converge in a specific sense when the sample size (observation window) tends to infinity, and if the hypothesis is regular, then these statistics are shown to be χ²-distributed under the hypothesis. The corresponding Rényi tests are shown to be consistent. The exact sizes and powers of asymptotically α-size Rényi, GLR and generalized Wald tests are evaluated for a concrete hypothesis about a bivariate Lévy process and moderate observation windows. In this concrete situation the exact sizes of the Rényi test of the order r?=?2 practically coincide with those of the GLR and generalized Wald tests but the exact powers of the Rényi test are on average somewhat better.     

Statistical inference of risk difference in K correlated 2×2 tables with structural zero

K correlated 2×2 tables with structural zero are commonly encountered in infectious disease studies. A hypothesis test for risk difference is considered in K independent 2×2 tables with structural zero in this paper. Score statistic, likelihood ratio statistic and Wald‐type statistic are proposed to test the hypothesis on the basis of stratified data and pooled data. Sample size formulae are derived for controlling a pre‐specified power or a pre‐determined confidence interval width. Our empirical results show that score statistic and likelihood ratio statistic behave better than Wald‐type statistic in terms of type I error rate and coverage probability, sample sizes based on stratified test are smaller than those based on the pooled test in the same design. A real example is used to illustrate the proposed methodologies. Copyright © 2009 John Wiley & Sons, Ltd.     

Small sample power of multivariate nonparametric tests for monotone trend

Bhattacharyya and Kioiz (1966) propose two multivariate nonparametric tests for monotone trend, one involving coordinate-wise Mann statistics and the other, coordinate-wise Spearman statistics. Dietz and Killeen (1981) propose a different test statistic based on coordinate-wise Mann statistics. The Pitman asymptotic relative efficiency of all three tests with respect to a normal theory competitor equals the cube root of the efficiency of a multivariate signed rank test with respect to Hotelling's T2. In this article, the small sample power of the nonparametric tests, the normal theory test, and a Bonferroni approach involving coordinate-wise univariate Mann or Spearman tests is examined in a simulation study. The Mann statistic of Dietz and Killeen and the Spearman statistic of Bhattacharyya and Klotz are found to perform well under both null and alternative hypotheses     

The effect of number of clusters and cluster size on statistical power and Type I error rates when testing random effects variance components in multilevel linear and logistic regression models

When using multilevel regression models that incorporate cluster-specific random effects, the Wald and the likelihood ratio (LR) tests are used for testing the null hypothesis that the variance of the random effects distribution is equal to zero. We conducted a series of Monte Carlo simulations to examine the effect of the number of clusters and the number of subjects per cluster on the statistical power to detect a non-null random effects variance and to compare the empirical type I error rates of the Wald and LR tests. Statistical power increased with increasing number of clusters and number of subjects per cluster. Statistical power was greater for the LR test than for the Wald test. These results applied to both the linear and logistic regressions, but were more pronounced for the latter. The use of the LR test is preferable to the use of the Wald test.     

Comparing two independent incidence rates using conditional and unconditional exact tests

Several unconditional exact tests, which are constructed to control the Type I error rate at the nominal level, for comparing two independent Poisson rates are proposed and compared to the conditional exact test using a binomial distribution. The unconditional exact test using binomial p-value, likelihood ratio, or efficient score as the test statistic improves the power in general, and are therefore recommended. Unconditional exact tests using Wald statistics, whether on the original or square-root scale, may be substantially less powerful than the conditional exact test, and is not recommended. An example is provided from a cardiovascular trial.     

A Class of Permutation Tests for the Equality of Two Marginal Survival Functions Using Paired Censored Data

We studied several test statistics for testing the equality of marginal survival functions of paired censored data. The null distribution of the test statistics was approximated by permutation. These tests do not require explicit modeling or estimation of the within-pair correlation, accommodate both paired data and singletons, and the computation is straightforward with most statistical software. Numerical studies showed that these tests have competitive size and power performance. One test statistic has higher power than previously published test statistics when the two survival functions under comparison cross. We illustrate use of these tests in a propensity score matched dataset.     

Parametric bootstrap and approximate tests for two Poisson variates

The parametric bootstrap tests and the asymptotic or approximate tests for detecting difference of two Poisson means are compared. The test statistics used are the Wald statistics with and without log-transformation, the Cox F statistic and the likelihood ratio statistic. It is found that the type I error rate of an asymptotic/approximate test may deviate too much from the nominal significance level α under some situations. It is recommended that we should use the parametric bootstrap tests, under which the four test statistics are similarly powerful and their type I error rates are all close to α. We apply the tests to breast cancer data and injurious motor vehicle crash data.     

近单整时间序列Scheffe预测模型的内生性及其修正

对于包含近单整时间序列的预测模型,在进行Scheffe检验时由于内生性问题的影响,导致参数统计量的检验水平过于保守,由此也相应降低了检验功效。通过加入解释变量的超前项与滞后项差分项的动态方法进行修正,并对修正前后的统计量有限样本性质进行仿真比较,结果显示这一修正方法可以有效降低内生性问题对Scheffe检验结果的影响。在小样本条件下,经过修正的Scheffe检验不仅提高了统计量的检验功效,同时明显减少了检验水平的扭曲现象。     

Local power and size properties of the LR,Wald, score and gradient tests in dispersion models

We derive asymptotic expansions for the nonnull distribution functions of the likelihood ratio, Wald, score and gradient test statistics in the class of dispersion models, under a sequence of Pitman alternatives. The asymptotic distributions of these statistics are obtained for testing a subset of regression parameters and for testing the precision parameter. Based on these nonnull asymptotic expansions, the power of all four tests, which are equivalent to first order, are compared. Furthermore, in order to compare the finite-sample performance of these tests in this class of models, Monte Carlo simulations are presented. An empirical application to a real data set is considered for illustrative purposes.     

Testing the Null Hypothesis of Nonstationary Long Memory Against the Alternative Hypothesis of a Nonlinear Ergodic Model

Interest in the interface of nonstationarity and nonlinearity has been increasing in the econometric literature. This paper provides a formal method of testing for nonstationary long memory against the alternative of a particular form of nonlinear ergodic processes; namely, exponential smooth transition autoregressive processes. In this regard, the current paper provides a significant generalization to existing unit root tests by allowing the null hypothesis to encompass a much larger class of nonstationary processes. The asymptotic theory associated with the proposed Wald statistic is derived, and Monte Carlo simulation results confirm that the Wald statistics have reasonably correct size and good power in small samples. In an application to real interest rates and the Yen real exchange rates, we find that the tests are able to distinguish between these competing processes in most cases, supporting the long-run Purchasing Power Parity (PPP) and Fisher hypotheses. But, there are a few cases in which long memory and nonlinear ergodic processes display similar characteristics and are thus confused with each other in small samples.     

Testing for multivariate heteroscedasticity

In this article, we propose a testing technique for multivariate heteroscedasticity, which is expressed as a test of linear restrictions in a multivariate regression model. Four test statistics with known asymptotical null distributions are suggested, namely the Wald, Lagrange multiplier (LM), likelihood ratio (LR) and the multivariate Rao F-test. The critical values for the statistics are determined by their asymptotic null distributions, but bootstrapped critical values are also used. The size, power and robustness of the tests are examined in a Monte Carlo experiment. Our main finding is that all the tests limit their nominal sizes asymptotically, but some of them have superior small sample properties. These are the F, LM and bootstrapped versions of Wald and LR tests.