Caliper pair-matching on a continuous variable in case-control studies

The use of matched pairs has been criticized as being less efficient than estimators based on random samples. This paper compares the mean square error of an analysis of covariance estimator based on random samples with two estimators based on caliper matched pairs. The first of these is a simple mean difference estimator and the second a regression estimator suggested by Rubin (1973b). Under conditions which commonly occur in epidemiologic case-control studies, both of the matched pair estimators can have smaller mean square errors than analysis o f covariance estimator. When there is a weak relationship between the matching and response variate, the mean difference estimator has a lower mean square error than the regression estimator.     

Estimation of the Memory Parameters of the Fractionally Integrated Separable Spatial Autoregressive (FISSAR(1, 1)) Model: A Simulation Study

In this article, we implement the Regression Method for estimating (d ₁, d ₂) of the FISSAR(1, 1) model. It is also possible to estimate d ₁ and d ₂ by Whittle's method. We also compute the estimated bias, standard error, and root mean square error by a simulation study. A comparison was made between the Regression Method of estimating d ₁ and d ₂ to that of the Whittle's method. It was found in this simulation study that the Regression Method of estimation was better when compare with the Whittle's estimator, in the sense that it had smaller root mean square errors (RMSE) values.     

基于因素模型的协高阶矩矩阵估计及其应用研究

在高阶矩投资组合中,使用传统样本估计方法会产生较高估计误差和模型设定误差。本文在多因素模型的基础上,给出一种改进的协高阶矩估计方法,分析了基于多因素模型压缩估计量的渐进一致性。蒙特卡洛模拟表明,多因素压缩估计量在有限样本中具有更小的平均绝对误差、根均方误差以及更高的平均绝对改进百分比,有效提高了协高阶矩矩阵估计的精度;即使在样本观测量比资产数目少时,估计的协高阶矩矩阵精度都会有较大提高。基于2005年6月至2019年5月沪深300成分股的高阶矩投资组合实证发现,多因素压缩方法与其他估计方法相比,在年化收益率上可以获得4.7%~32.8%的提升,最大回撤能够下降3.7%~18.3%,表明使用多因素压缩估计方法构建的投资组合有更大的可能获得更多货币效用增益,以及面临亏损时,产生的最大亏损更小。该方法有助于金融机构或理性投资者在进行投资组合时减小投资损失,获得更好的投资回报。     

Asymptotic properties of the ols and grls estimator for the replicated functional relationship model

For the simple linear functional relationship model with replication, the asymptotic properties of the ordinary (OLS) and grouping least squares (GRLS) estimator of the slope are investi- gated under the assumption of normally distributed errors with unknown covariance matrix. The relative performance of the OLS and GRLS estimator is compared in terms of the asymptotic mean square error, and a set of critical parameters are identified for determining the dominance of one estimator over the other. It is also shown that the GRLS estimator is asymptoticallyequivalent to the maximum likelihood (ML) estimator under the given assumptions.     

Design considerations for small experiments and simple logistic regression

Inference for a generalized linear model is generally performed using asymptotic approximations for the bias and the covariance matrix of the parameter estimators. For small experiments, these approximations can be poor and result in estimators with considerable bias. We investigate the properties of designs for small experiments when the response is described by a simple logistic regression model and parameter estimators are to be obtained by the maximum penalized likelihood method of Firth [Firth, D., 1993, Bias reduction of maximum likelihood estimates. Biometrika, 80, 27–38]. Although this method achieves a reduction in bias, we illustrate that the remaining bias may be substantial for small experiments, and propose minimization of the integrated mean square error, based on Firth's estimates, as a suitable criterion for design selection. This approach is used to find locally optimal designs for two support points.     

On the bias and mean square error of the least square estimator in a regression model with two inequality constraints and multivariate t error terms

We derive and numerically evaluate the bias and mean square error of the inequality constrained least squares estimator in a model with two inequality constraints and multivariate terror terms. Our results suggest that qualitatively, the estimator properties found for models with normal errors carry over to the case of multivariate terrors.     

Linear model estimation errors with estimated design parameters

The problem of error estimation of parameters b in a linear model,Y = Xb+ e, is considered when the elements of the design matrix X are functions of an unknown ‘design’ parameter vector c. An estimated value c is substituted in X to obtain a derived design matrix [Xtilde]. Even though the usual linear model conditions are not satisfied with [Xtilde], there are situations in physical applications where the least squares solution to the parameters is used without concern for the magnitude of the resulting error. Such a solution can suffer from serious errors.

This paper examines bias and covariance errors of such estimators. Using a first-order Taylor series expansion, we derive approximations to the bias and covariance matrix of the estimated parameters. The bias approximation is a sum of two terms:One is due to the dependence between ? and Y; the other is due to the estimation errors of ? and is proportional to b, the parameter being estimated. The covariance matrix approximation, on the other hand, is composed of three omponents:One component is due to the dependence between ? and Y; the second is the covariance matrix ∑_b corresponding to the minimum variance unbiased b, as if the design parameters were known without error; and the third is an additional component due to the errors in the design parameters. It is shown that the third error component is directly proportional to bb'. Thus, estimation of large parameters with wrong design matrix [Xtilde] will have larger errors of estimation. The results are illustrated with a simple linear example.     

ON UMP INVARIANT F-TEST PROCEDURES IN A GENERAL LINEAR MODEL

A simple method of setting linear hypotheses for a split mean vector testable by F-tests in a general linear model, when the covariance matrix has a general form and is completely unknown, is provided by extending the method discussed in Ukita et al. The critical functions in these F-tests are constructed as UMP invariants, when the covariance matrix has a known structure. Further critical functions in F-tests of linear hypotheses for the other split mean vector in the model are shown to be UMP invariant if the same known structure of the covariance matrix is assumed.     

A modified Cp statistic in a system-of-equations model

A new statistic, SΓ(p), is developed for variable selection in a system-of-equations model. The standardized total mean square error in the SΓ(p)statistic is weighted by the covariance matrix of dependent variables instead of the error covariance matrix of the true model as in the original definition. The new statistic can be also used for model selection in the non-nested models. The estimate of SΓ(p), SC(p), is derived and shown to become SC_ε(p) in the similar form of C_p in a single-equation model when the covariance matrix of sampled dependent variables is replaced by the error covariance matrix under the full model.     

Three estimators for the poisson regression model with measurement errors

We consider two consistent estimators for the parameters of the linear predictor in the Poisson regression model, where the covariate is measured with errors. The measurement errors are assumed to be normally distributed with known error variance σ _u ² . The SQS estimator, based on a conditional mean-variance model, takes the distribution of the latent covariate into account, and this is here assumed to be a normal distribution. The CS estimator, based on a corrected score function, does not use the distribution of the latent covariate. Nevertheless, for small σ _u ² , both estimators have identical asymptotic covariance matrices up to the order of σ _u ² . We also compare the consistent estimators to the naive estimator, which is based on replacing the latent covariate with its (erroneously) measured counterpart. The naive estimator is biased, but has a smaller covariance matrix than the consistent estimators (at least up to the order of σ _u ² ).     

Bootstrapping analogs of the one way MANOVA test

Abstract

Analogs of the classical one way MANOVA model have recently been suggested that do not assume that population covariance matrices are equal or that the error vector distribution is known. These tests are based on the sample mean and sample covariance matrix corresponding to each of the p populations. We show how to extend these tests using other measures of location such as the trimmed mean or coordinatewise median. These new bootstrap tests can have some outlier resistance, and can perform better than the tests based on the sample mean if the error vector distribution is heavy tailed.     

Small-area estimation by combining time-series and cross-sectional data

A model involving autocorrelated random effects and sampling errors is proposed for small-area estimation, using both time-series and cross-sectional data. The sampling errors are assumed to have a known block-diagonal covariance matrix. This model is an extension of a well-known model, due to Fay and Herriot (1979), for cross-sectional data. A two-stage estimator of a small-area mean for the current period is obtained under the proposed model with known autocorrelation, by first deriving the best linear unbiased prediction estimator assuming known variance components, and then replacing them with their consistent estimators. Extending the approach of Prasad and Rao (1986, 1990) for the Fay-Herriot model, an estimator of mean squared error (MSE) of the two-stage estimator, correct to a second-order approximation for a small or moderate number of time points, T, and a large number of small areas, m, is obtained. The case of unknown autocorrelation is also considered. Limited simulation results on the efficiency of two-stage estimators and the accuracy of the proposed estimator of MSE are présentés.     

A very simple proof of the multivariate Chebyshev's inequality

Abstract

In this short note, a very simple proof of the Chebyshev's inequality for random vectors is given. This inequality provides a lower bound for the percentage of the population of an arbitrary random vector X with finite mean μ = E(X) and a positive definite covariance matrix V = Cov(X) whose Mahalanobis distance with respect to V to the mean μ is less than a fixed value. The main advantage of the proof is that it is a simple exercise for a first year probability course. An alternative proof based on principal components is also provided. This proof can be used to study the case of a singular covariance matrix V.     

Identification of the linear factor model

Abstract

This paper provides several new results on identification of the linear factor model. The model allows for correlated latent factors and dependence among the idiosyncratic errors. I also illustrate identification under a dedicated measurement structure and other reduced rank restrictions. I use these results to study identification in a model with both observed covariates and latent factors. The analysis emphasizes the different roles played by restrictions on the error covariance matrix, restrictions on the factor loadings and the factor covariance matrix, and restrictions on the coefficients on covariates. The identification results are simple, intuitive, and directly applicable to many settings.     

Effects of the estimation of covariance matrix parameters in the generalized multivariate linear model

We Consider the generalized multivariate linear model and assume the covariance matrix of the p x 1 vector of responses on a given individual can be represented in the general linear structure form described by Anderson (1973). The effects of the use of estimates of the parameters of the covariance matrix on the generalized least squares estimator of the regression coefficients and on the prediction of a portion of a future vector, when only the first portion of the vector has been observed, are investigated. Approximations are derived for the covariance matrix of the generalized least squares estimator and for the mean square error matrix of the usual predictor, for the practical case where estimated parameters are used.     

Testing sphericity and intraclass covariance structures under a growth curve model in high dimension

In this article, we consider the problem of testing (a) sphericity and (b) intraclass covariance structure under a growth curve model. The maximum likelihood estimator (MLE) for the mean in a growth curve model is a weighted estimator with the inverse of the sample covariance matrix which is unstable for large p close to N and singular for p larger than N. The MLE for the covariance matrix is based on the MLE for the mean, which can be very poor for p close to N. For both structures (a) and (b), we modify the MLE for the mean to an unweighted estimator and based on this estimator we propose a new estimator for the covariance matrix. This new estimator leads to new tests for (a) and (b). We also propose two other tests for each structure, which are just based on the sample covariance matrix.

To compare the performance of all four tests we compute for each structure (a) and (b) the attained significance level and the empirical power. We show that one of the tests based on the sample covariance matrix is better than the likelihood ratio test based on the MLE.     

A new heteroskedasticity-consistent covariance matrix estimator for the linear regression model

The assumption that all random errors in the linear regression model share the same variance (homoskedasticity) is often violated in practice. The ordinary least squares estimator of the vector of regression parameters remains unbiased, consistent and asymptotically normal under unequal error variances. Many practitioners then choose to base their inferences on such an estimator. The usual practice is to couple it with an asymptotically valid estimation of its covariance matrix, and then carry out hypothesis tests that are valid under heteroskedasticity of unknown form. We use numerical integration methods to compute the exact null distributions of some quasi-t test statistics, and propose a new covariance matrix estimator. The numerical results favor testing inference based on the estimator we propose.     

A martingale residual diagnostic for longitudinal and recurrent event data

One method of assessing the fit of an event history model is to plot the empirical standard deviation of standardised martingale residuals. We develop an alternative procedure which is valid also in the presence of measurement error and applicable to both longitudinal and recurrent event data. Since the covariance between martingale residuals at times t ₀ and t > t ₀ is independent of t, a plot of these covariances should, for fixed t ₀, have no time trend. A test statistic is developed from the increments in the estimated covariances, and we investigate its properties under various types of model misspecification. Applications of the approach are presented using two Brazilian studies measuring daily prevalence and incidence of infant diarrhoea and a longitudinal study into treatment of schizophrenia.     

Bayes designs for multiple linear regression on the unit sphere

We deal with experimental designs minimizing the mean square error of the linear BAYES estimator for the parameter vector of a multiple linear regression model where the experimental region is the k-dimensional unit sphere. After computing the uniquely determined optimum information matrix, we construct, separately for the homogeneous and the inhomogeneous model, both approximate and exact designs having such an information matrix.