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1.
This article recasts the optimal allocations of coverage limits for two independent random losses. Under some regularity conditions on the two concerned probability density functions, we build the sufficient and necessary condition for the existence of the optimal allocation of coverage limits, and derive the optimal allocation whenever they do exist. The results supplement Lu and Meng (2011 Lu, Z.Y., Meng, L.L. (2011). Stochastic comparisons for allocations of upper limits and deductibles with applications. Insur.: Math. Econ. 48:338343.[Crossref], [Web of Science ®] [Google Scholar], Proposition 5.2) and Hu and Wang (2014 Hu, S., Wang, R. (2014). Stochastic comparisons and optimal allocation for policy limits and deductibles. Commun. Stat. – Theory Methods 43:151164.[Taylor &; Francis Online], [Web of Science ®] [Google Scholar], Theorem 5.1).  相似文献   

2.
A variety of statistical approaches have been suggested in the literature for the analysis of bounded outcome scores (BOS). In this paper, we suggest a statistical approach when BOSs are repeatedly measured over time and used as predictors in a regression model. Instead of directly using the BOS as a predictor, we propose to extend the approaches suggested in [16 E. Lesaffre, D. Rizopoulos, and R. Tsonaka, The logistics-transform for bounded outcome scores, Biostatistics 8 (2007), pp. 7285. doi: 10.1093/biostatistics/kxj034[Crossref], [PubMed], [Web of Science ®] [Google Scholar],21 M. Molas and E. Lesaffre, A comparison of the three random effects approaches to analyse repeated bounded outcome scores with an application in a stroke revalidation study, Stat. Med. 27 (2008), pp. 66126633. doi: 10.1002/sim.3432[Crossref], [PubMed], [Web of Science ®] [Google Scholar],28 R. Tsonaka, D. Rizopoulos, and E. Lesaffre, Power and sample size calculations for discrete bounded outcome scores, Stat. Med. 25 (2006), pp. 42414252. doi: 10.1002/sim.2679[Crossref], [PubMed], [Web of Science ®] [Google Scholar]] to a joint modeling setting. Our approach is illustrated on longitudinal profiles of multiple patients’ reported outcomes to predict the current clinical status of rheumatoid arthritis patients by a disease activities score of 28 joints (DAS28). Both a maximum likelihood as well as a Bayesian approach is developed.  相似文献   

3.
This article proposes an asymptotic expansion for the Studentized linear discriminant function using two-step monotone missing samples under multivariate normality. The asymptotic expansions related to discriminant function have been obtained for complete data under multivariate normality. The result derived by Anderson (1973 Anderson , T. W. ( 1973 ). An asymptotic expansion of the distribution of the Studentized classification statistic W . The Annals of Statistics 1 : 964972 .[Crossref], [Web of Science ®] [Google Scholar]) plays an important role in deciding the cut-off point that controls the probabilities of misclassification. This article provides an extension of the result derived by Anderson (1973 Anderson , T. W. ( 1973 ). An asymptotic expansion of the distribution of the Studentized classification statistic W . The Annals of Statistics 1 : 964972 .[Crossref], [Web of Science ®] [Google Scholar]) in the case of two-step monotone missing samples under multivariate normality. Finally, numerical evaluations by Monte Carlo simulations were also presented.  相似文献   

4.
This paper presents a new variable weight method, called the singular value decomposition (SVD) approach, for Kohonen competitive learning (KCL) algorithms based on the concept of Varshavsky et al. [18 R. Varshavsky, A. Gottlieb, M. Linial, and D. Horn, Novel unsupervised feature filtering of bilogical data, Bioinformatics 22 (2006), pp. 507513.[Crossref], [PubMed], [Web of Science ®] [Google Scholar]]. Integrating the weighted fuzzy c-means (FCM) algorithm with KCL, in this paper, we propose a weighted fuzzy KCL (WFKCL) algorithm. The goal of the proposed WFKCL algorithm is to reduce the clustering error rate when data contain some noise variables. Compared with the k-means, FCM and KCL with existing variable-weight methods, the proposed WFKCL algorithm with the proposed SVD's weight method provides a better clustering performance based on the error rate criterion. Furthermore, the complexity of the proposed SVD's approach is less than Pal et al. [17 S.K. Pal, R.K. De, and J. Basak, Unsupervised feature evaluation: a neuro-fuzzy approach, IEEE. Trans. Neural Netw. 11 (2000), pp. 366376.[Crossref], [PubMed], [Web of Science ®] [Google Scholar]], Wang et al. [19 X.Z. Wang, Y.D. Wang, and L.J. Wang, Improving fuzzy c-means clustering based on feature-weight learning, Pattern Recognit. Lett. 25 (2004), pp. 11231132.[Crossref], [Web of Science ®] [Google Scholar]] and Hung et al. [9 W. -L. Hung, M. -S. Yang, and D. -H. Chen, Bootstrapping approach to feature-weight selection in fuzzy c-means algorithms with an application in color image segmentation, Pattern Recognit. Lett. 29 (2008), pp. 13171325.[Crossref], [Web of Science ®] [Google Scholar]].  相似文献   

5.
Competing models arise naturally in many research fields, such as survival analysis and economics, when the same phenomenon of interest is explained by different researcher using different theories or according to different experiences. The model selection problem is therefore remarkably important because of its great importance to the subsequent inference; Inference under a misspecified or inappropriate model will be risky. Existing model selection tests such as Vuong's tests [26 Q.H. Vuong, Likelihood ratio test for model selection and non-nested hypothesis, Econometrica 57 (1989), pp. 307333. doi: 10.2307/1912557[Crossref], [Web of Science ®] [Google Scholar]] and Shi's non-degenerate tests [21 X. Shi, A non-degenerate Vuong test, Quant. Econ. 6 (2015), pp. 85121. doi: 10.3982/QE382[Crossref], [Web of Science ®] [Google Scholar]] suffer from the variance estimation and the departure of the normality of the likelihood ratios. To circumvent these dilemmas, we propose in this paper an empirical likelihood ratio (ELR) tests for model selection. Following Shi [21 X. Shi, A non-degenerate Vuong test, Quant. Econ. 6 (2015), pp. 85121. doi: 10.3982/QE382[Crossref], [Web of Science ®] [Google Scholar]], a bias correction method is proposed for the ELR tests to enhance its performance. A simulation study and a real-data analysis are provided to illustrate the performance of the proposed ELR tests.  相似文献   

6.
This article suggests random and fixed effects spatial two-stage least squares estimators for the generalized mixed regressive spatial autoregressive panel data model. This extends the generalized spatial panel model of Baltagi et al. (2013 Baltagi, B. H., Egger, P., Pfaffermayr, M. (2013). A generalized spatial panel data model with random effects. Econometric Reviews 32:650685.[Taylor &; Francis Online], [Web of Science ®] [Google Scholar]) by the inclusion of a spatial lag term. The estimation method utilizes the Generalized Moments method suggested by Kapoor et al. (2007 Kapoor, M., Kelejian, H. H., Prucha, I. R. (2007). Panel data models with spatially correlated error components. Journal of Econometrics 127(1):97130.[Crossref], [Web of Science ®] [Google Scholar]) for a spatial autoregressive panel data model. We derive the asymptotic distributions of these estimators and suggest a Hausman test a la Mutl and Pfaffermayr (2011 Mutl, J., Pfaffermayr, M. (2011). The Hausman test in a Cliff and Ord panel model. Econometrics Journal 14:4876.[Crossref], [Web of Science ®] [Google Scholar]) based on the difference between these estimators. Monte Carlo experiments are performed to investigate the performance of these estimators as well as the corresponding Hausman test.  相似文献   

7.
In this article, we consider investigating whether any of k treatments are better than a control under the assumption of each treatment mean being no less than the control mean. A classic problem is to find the simultaneous confidence bounds for the difference between each treatment and the control. Compared with hypothesis testing, confidence bounds have the attractive advantage of telling more information about the effective treatment. Generally, the one-sided lower bounds are provided as it's enough for detecting effective treatment and the one-sided lower bounds has sharper lower bands than two-sided ones. However, a two-sided procedure provides both upper and lower bounds on the differences. In this article, we develop a new procedure which combines the good aspects of both the one-sided and the two-sided procedures. This new procedure has the same inferential sensitivity of the one-sided procedure proposed by Zhao (2007 Zhao , H. B. ( 2007 ). Comparing several treatments with a control . J. Statist. Plann. Infer. 137 : 29963006 .[Crossref], [Web of Science ®] [Google Scholar]) while also providing simultaneous two-sided bounds for the differences between treatments and the control. By our computation results, we find the new procedure is better than Hayter, Miwa and Liu's procedure (Hayter et al., 2000 Hayter , A. J. , Miwa , T. , Liu , W. ( 2000 ). Combining the advantages of one-sided and two-sided procedures for comparing several treatments with a control . J. Statist. Plann. Infer. 86 : 8199 .[Crossref], [Web of Science ®] [Google Scholar]), when the sample size is balanced. We also illustrate the new procedure by an example.  相似文献   

8.
Two-period crossover design is one of the commonly used designs in clinical trials. But, the estimation of treatment effect is complicated by the possible presence of carryover effect. It is known that ignoring the carryover effect when it exists can lead to poor estimates of the treatment effect. The classical approach by Grizzle (1965 Grizzle, J.E. (1965). The two-period change-over design and its use in clinical trials. Biometrics 21:467480. See Grizzle (1974) for corrections.[Crossref], [PubMed], [Web of Science ®] [Google Scholar]) consists of two stages. First, a preliminary test is conducted on carryover effect. If the carryover effect is significant, analysis is based only on data from period one; otherwise, analysis is based on data from both periods. A Bayesian approach with improper priors was proposed by Grieve (1985 Grieve, A.P. (1985). A Bayesian analysis of the two-period crossover design for clinical trials. Biometrics 41:979990.[Crossref], [PubMed], [Web of Science ®] [Google Scholar]) which uses a mixture of two models: a model with carryover effect and another without. The indeterminacy of the Bayes factor due to the arbitrary constant in the improper prior was addressed by assigning a minimally discriminatory value to the constant. In this article, we present an objective Bayesian estimation approach to the two-period crossover design which is also based on a mixture model, but using the commonly recommended Zellner–Siow g-prior. We provide simulation studies and a real data example and compare the numerical results with Grizzle (1965 Grizzle, J.E. (1965). The two-period change-over design and its use in clinical trials. Biometrics 21:467480. See Grizzle (1974) for corrections.[Crossref], [PubMed], [Web of Science ®] [Google Scholar])’s and Grieve (1985 Grieve, A.P. (1985). A Bayesian analysis of the two-period crossover design for clinical trials. Biometrics 41:979990.[Crossref], [PubMed], [Web of Science ®] [Google Scholar])’s approaches.  相似文献   

9.
Soltani and Mohammadpour (2006 Soltani , A. R. , Mohammadpour , M. (2006). Moving average representations for multivariate stationary processes. J. Time Ser. Anal. 27(6):831841.[Crossref], [Web of Science ®] [Google Scholar]) observed that in general the backward and forward moving average coefficients, correspondingly, for the multivariate stationary processes, unlike the univariate processes, are different. This has stimulated researches concerning derivations of forward moving average coefficients in terms of the backward moving average coefficients. In this article we develop a practical procedure whenever the underlying process is a multivariate moving average (or univariate periodically correlated) process of finite order. Our procedure is based on two key observations: order reduction (Li, 2005 Li , L. M. ( 2005 ). Factorization of moving average spectral densities by state space representations and stacking . J. Multivariate Anal. 96 : 425438 .[Crossref], [Web of Science ®] [Google Scholar]) and first-order analysis (Mohammadpour and Soltani, 2010 Mohammadpour , M. , Soltani , A. R. ( 2010 ). Forward moving average representation for multivariate MA(1) processes . Commun. Statist. Theory Meth. 39 : 729737 .[Taylor &; Francis Online], [Web of Science ®] [Google Scholar]).  相似文献   

10.
Adaptive clinical trial designs can often improve drug-study efficiency by utilizing data obtained during the course of the trial. We present a novel Bayesian two-stage adaptive design for Phase II clinical trials with Poisson-distributed outcomes that allows for person-observation-time adjustments for early termination due to either futility or efficacy. Our design is motivated by the adaptive trial from [9 V. Sambucini, A Bayesian predictive two-stage design for Phase II clinical trials, Stat. Med. 27 (2008), pp. 11991224. doi: 10.1002/sim.3021[Crossref], [PubMed], [Web of Science ®] [Google Scholar]], which uses binomial data. Although many frequentist and Bayesian two-stage adaptive designs for count data have been proposed in the literature, many designs do not allow for person-time adjustments after the first stage. This restriction limits flexibility in the study design. However, our proposed design allows for such flexibility by basing the second-stage person-time on the first-stage observed-count data. We demonstrate the implementation of our Bayesian predictive adaptive two-stage design using a hypothetical Phase II trial of Immune Globulin (Intravenous).  相似文献   

11.
This paper treats the problem of stochastic comparisons for the extreme order statistics arising from heterogeneous beta distributions. Some sufficient conditions involved in majorization-type partial orders are provided for comparing the extreme order statistics in the sense of various magnitude orderings including the likelihood ratio order, the reversed hazard rate order, the usual stochastic order, and the usual multivariate stochastic order. The results established here strengthen and extend those including Kochar and Xu (2007 Kochar, S.C., Xu, M. (2007). Stochastic comparisons of parallel systems when components have proportional hazard rates. Probab. Eng. Inf. Sci. 21:597609.[Crossref], [Web of Science ®] [Google Scholar]), Mao and Hu (2010 Mao, T., Hu, T. (2010). Equivalent characterizations on orderings of order statistics and sample ranges. Probab. Eng. Inf. Sci. 24:245262.[Crossref], [Web of Science ®] [Google Scholar]), Balakrishnan et al. (2014 Balakrishnan, N., Barmalzan, G., Haidari, A. (2014). On usual multivariate stochastic ordering of order statistics from heterogeneous beta variables. J. Multivariate Anal. 127:147150.[Crossref], [Web of Science ®] [Google Scholar]), and Torrado (2015 Torrado, N. (2015). On magnitude orderings between smallest order statistics from heterogeneous beta distributions. J. Math. Anal. Appl. 426:824838.[Crossref], [Web of Science ®] [Google Scholar]). A real application in system assembly and some numerical examples are also presented to illustrate the theoretical results.  相似文献   

12.
Ye Li 《Econometric Reviews》2017,36(1-3):289-353
We consider issues related to inference about locally ordered breaks in a system of equations, as originally proposed by Qu and Perron (2007 Qu, Z., Perron, P. (2007). Estimating and testing structural changes in multivariate regressions. Econometrica 75:459502.[Crossref], [Web of Science ®] [Google Scholar]). These apply when break dates in different equations within the system are not separated by a positive fraction of the sample size. This allows constructing joint confidence intervals of all such locally ordered break dates. We extend the results of Qu and Perron (2007 Qu, Z., Perron, P. (2007). Estimating and testing structural changes in multivariate regressions. Econometrica 75:459502.[Crossref], [Web of Science ®] [Google Scholar]) in several directions. First, we allow the covariates to be any mix of trends and stationary or integrated regressors. Second, we allow for breaks in the variance-covariance matrix of the errors. Third, we allow for multiple locally ordered breaks, each occurring in a different equation within a subset of equations in the system. Via some simulation experiments, we show first that the limit distributions derived provide good approximations to the finite sample distributions. Second, we show that forming confidence intervals in such a joint fashion allows more precision (tighter intervals) compared to the standard approach of forming confidence intervals using the method of Bai and Perron (1998 Bai, J., Perron, P. (1998). Estimating and testing linear models with multiple structural changes. Econometrica 66:4778.[Crossref], [Web of Science ®] [Google Scholar]) applied to a single equation. Simulations also indicate that using the locally ordered break confidence intervals yields better coverage rates than using the framework for globally distinct breaks when the break dates are separated by roughly 10% of the total sample size.  相似文献   

13.
This article considers constructing confidence intervals for the date of a structural break in linear regression models. Using extensive simulations, we compare the performance of various procedures in terms of exact coverage rates and lengths of the confidence intervals. These include the procedures of Bai (1997 Bai, J. (1997). Estimation of a change point in multiple regressions. Review of Economics and Statistics 79:551563.[Crossref], [Web of Science ®] [Google Scholar]) based on the asymptotic distribution under a shrinking shift framework, Elliott and Müller (2007 Elliott, G., Müller, U. (2007). Confidence sets for the date of a single break in linear time series regressions. Journal of Econometrics 141:11961218.[Crossref], [Web of Science ®] [Google Scholar]) based on inverting a test locally invariant to the magnitude of break, Eo and Morley (2015 Eo, Y., Morley, J. (2015). Likelihood-ratio-based confidence sets for the timing of structural breaks. Quantitative Economics 6:463497.[Crossref], [Web of Science ®] [Google Scholar]) based on inverting a likelihood ratio test, and various bootstrap procedures. On the basis of achieving an exact coverage rate that is closest to the nominal level, Elliott and Müller's (2007 Elliott, G., Müller, U. (2007). Confidence sets for the date of a single break in linear time series regressions. Journal of Econometrics 141:11961218.[Crossref], [Web of Science ®] [Google Scholar]) approach is by far the best one. However, this comes with a very high cost in terms of the length of the confidence intervals. When the errors are serially correlated and dealing with a change in intercept or a change in the coefficient of a stationary regressor with a high signal-to-noise ratio, the length of the confidence interval increases and approaches the whole sample as the magnitude of the change increases. The same problem occurs in models with a lagged dependent variable, a common case in practice. This drawback is not present for the other methods, which have similar properties. Theoretical results are provided to explain the drawbacks of Elliott and Müller's (2007 Elliott, G., Müller, U. (2007). Confidence sets for the date of a single break in linear time series regressions. Journal of Econometrics 141:11961218.[Crossref], [Web of Science ®] [Google Scholar]) method.  相似文献   

14.
This paper studies the allocations of two non identical active redundancies in series systems in terms of the reversed hazard rate order and hazard rate order, which generalizes some results built in Valdés and Zequeira (2003 Valdés, J. E., and R. I. Zequeira 2003. On the optimal allocation of an active redundancy in a two-component series system. Stat. Probab. Lett. 63:32532.[Crossref], [Web of Science ®] [Google Scholar], 2006 Valdés, J. E., and R. I. Zequeira 2006. On the optimal allocation of two active redundancies in a two-component series system. Oper. Res. Lett. 34:4952.[Crossref], [Web of Science ®] [Google Scholar]).  相似文献   

15.
In this article, we propose a weighted simulated integrated conditional moment (WSICM) test of the validity of parametric specifications of conditional distribution models for stationary time series data, by combining the weighted integrated conditional moment (ICM) test of Bierens (1984 Bierens, H. J. (1984). Model specification testing of time series regressions. Journal of Econometrics 26:323353.[Crossref], [Web of Science ®] [Google Scholar]) for time series regression models with the simulated ICM test of Bierens and Wang (2012 Bierens, H. J., Wang, L. (2012). Integrated conditional moment tests for parametric conditional distributions. Econometric Theory 28:328362.[Crossref], [Web of Science ®] [Google Scholar]) of conditional distribution models for cross-section data. To the best of our knowledge, no other consistent test for parametric conditional time series distributions has been proposed yet in the literature, despite consistency claims made by some authors.  相似文献   

16.
Karlis and Santourian [14 D. Karlis and A. Santourian, Model-based clustering with non-elliptically contoured distribution, Stat. Comput. 19 (2009), pp. 7383. doi: 10.1007/s11222-008-9072-0[Crossref], [Web of Science ®] [Google Scholar]] proposed a model-based clustering algorithm, the expectation–maximization (EM) algorithm, to fit the mixture of multivariate normal-inverse Gaussian (NIG) distribution. However, the EM algorithm for the mixture of multivariate NIG requires a set of initial values to begin the iterative process, and the number of components has to be given a priori. In this paper, we present a learning-based EM algorithm: its aim is to overcome the aforementioned weaknesses of Karlis and Santourian's EM algorithm [14 D. Karlis and A. Santourian, Model-based clustering with non-elliptically contoured distribution, Stat. Comput. 19 (2009), pp. 7383. doi: 10.1007/s11222-008-9072-0[Crossref], [Web of Science ®] [Google Scholar]]. The proposed learning-based EM algorithm was first inspired by Yang et al. [24 M.-S. Yang, C.-Y. Lai, and C.-Y. Lin, A robust EM clustering algorithm for Gaussian mixture models, Pattern Recognit. 45 (2012), pp. 39503961. doi: 10.1016/j.patcog.2012.04.031[Crossref], [Web of Science ®] [Google Scholar]]: the process of how they perform self-clustering was then simulated. Numerical experiments showed promising results compared to Karlis and Santourian's EM algorithm. Moreover, the methodology is applicable to the analysis of extrasolar planets. Our analysis provides an understanding of the clustering results in the ln?P?ln?M and ln?P?e spaces, where M is the planetary mass, P is the orbital period and e is orbital eccentricity. Our identified groups interpret two phenomena: (1) the characteristics of two clusters in ln?P?ln?M space might be related to the tidal and disc interactions (see [9 I.G. Jiang, W.H. Ip, and L.C. Yeh, On the fate of close-in extrasolar planets, Astrophys. J. 582 (2003), pp. 449454. doi: 10.1086/344590[Crossref], [Web of Science ®] [Google Scholar]]); and (2) there are two clusters in ln?P?e space.  相似文献   

17.
This article is concerned with sphericity test for the two-way error components panel data model. It is found that the John statistic and the bias-corrected LM statistic recently developed by Baltagi et al. (2011 Baltagi, B. H., Feng, Q., Kao, C. (2011). Testing for sphericity in a fixed effects panel data model. Econometrics Journal 14:2547.[Crossref], [Web of Science ®] [Google Scholar])Baltagi et al. (2012 Baltagi, B. H., Feng, Q., Kao, C. (2012). A Lagrange multiplier test for cross-sectional dependence in a fixed effects panel data model. Journal of Econometrics 170:164177.[Crossref], [Web of Science ®] [Google Scholar], which are based on the within residuals, are not helpful under the present circumstances even though they are in the one-way fixed effects model. However, we prove that when the within residuals are properly transformed, the resulting residuals can serve to construct useful statistics that are similar to those of Baltagi et al. (2011 Baltagi, B. H., Feng, Q., Kao, C. (2011). Testing for sphericity in a fixed effects panel data model. Econometrics Journal 14:2547.[Crossref], [Web of Science ®] [Google Scholar])Baltagi et al. (2012 Baltagi, B. H., Feng, Q., Kao, C. (2012). A Lagrange multiplier test for cross-sectional dependence in a fixed effects panel data model. Journal of Econometrics 170:164177.[Crossref], [Web of Science ®] [Google Scholar]). Simulation results show that the newly proposed statistics perform well under the null hypothesis and several typical alternatives.  相似文献   

18.
Noting that many economic variables display occasional shifts in their second order moments, we investigate the performance of homogenous panel unit root tests in the presence of permanent volatility shifts. It is shown that in this case the test statistic proposed by Herwartz and Siedenburg (2008 Herwartz, H., Siedenburg, F. (2008). Homogenous panel unit root tests under cross-sectional dependence: Finite sample modifications and the wild bootstrap. Computational Statistics and Data Analysis 53(1):137150.[Crossref], [Web of Science ®] [Google Scholar]) is asymptotically standard Gaussian. By means of a simulation study we illustrate the performance of first and second generation panel unit root tests and undertake a more detailed comparison of the test in Herwartz and Siedenburg (2008 Herwartz, H., Siedenburg, F. (2008). Homogenous panel unit root tests under cross-sectional dependence: Finite sample modifications and the wild bootstrap. Computational Statistics and Data Analysis 53(1):137150.[Crossref], [Web of Science ®] [Google Scholar]) and its heteroskedasticity consistent Cauchy counterpart introduced in Demetrescu and Hanck (2012a Demetrescu, M., Hanck, C. (2012a). A simple nonstationary-volatility robust panel unit root test. Economics Letters 117(2):1013.[Crossref], [Web of Science ®] [Google Scholar]). As an empirical illustration, we reassess evidence on the Fisher hypothesis with data from nine countries over the period 1961Q2–2011Q2. Empirical evidence supports panel stationarity of the real interest rate for the entire subperiod. With regard to the most recent two decades, the test results cast doubts on market integration, since the real interest rate is diagnosed nonstationary.  相似文献   

19.
A proposed method based on frailty models is used to identify longitudinal biomarkers or surrogates for a multivariate survival. This method is an extention of earlier models by Wulfsohn and Tsiatis (1997 Wulfsohn , M. S. , Tsiatis , A. A. ( 1997 ). A joint model for survival and longitudinal data measured with error . Biometrics 53 ( 1 ): 330339 .[Crossref], [PubMed], [Web of Science ®] [Google Scholar]) and Song et al. (2002 Song , X. , Davidian , M. , Tsiatis , A. A. ( 2002 ). A Semiparametric likelihood approach to joint modeling of longitudinal and time-to-event data . Biometrics 58 ( 4 ): 742753 .[Crossref], [PubMed], [Web of Science ®] [Google Scholar]). In this article, similar to Henderson et al. (2002 Henderson , R. , Diggle , P. J. , Dobson , A. ( 2002 ). Identification and efficacy of longitudinal markers for survival . Biostatistics 3 ( 1 ): 3350 .[Crossref], [PubMed], [Web of Science ®] [Google Scholar]), a joint likelihood function combines the likelihood functions of the longitudinal biomarkers and the multivariate survival times. We use simulations to explore how the number of individuals, the number of time points per individual and the functional form of the random effects from the longitudianl biomarkers influence the power to detect the association of a longitudinal biomarker and the multivariate survival time. The proposed method is illustrate by using the gastric cancer data.  相似文献   

20.
The Jackknife-after-bootstrap (JaB) technique originally developed by Efron [8 B. Efron, Jackknife-after-bootstrap standard errors and influence functions, J. R. Stat. Soc. 54 (1992), pp. 83127. [Google Scholar]] has been proposed as an approach to improve the detection of influential observations in linear regression models by Martin and Roberts [12 M.A. Martin and S. Roberts, Jackknife-after-bootstrap regression influence diagnostics, J. Nonparametr. Stat. 22 (2010), pp. 257269. doi: 10.1080/10485250903287906[Taylor &; Francis Online], [Web of Science ®] [Google Scholar]] and Beyaztas and Alin [2 U. Beyaztas and A. Alin, Jackknife-after-bootstrap method for detection of influential observations in linear regression model, Comm. Statist. Simulation Comput. 42 (2013), pp. 12561267. doi: 10.1080/03610918.2012.661908[Taylor &; Francis Online], [Web of Science ®] [Google Scholar]]. The method is based on the use of percentile-method confidence intervals to provide improved cut-off values for several single case-deletion influence measures. In order to improve JaB, we propose using robust versions of Efron [7 B. Efron, Better bootstrap confidence intervals, J. Amer. Statist. Assoc. 82 (1987), pp. 171185. doi: 10.1080/01621459.1987.10478410[Taylor &; Francis Online], [Web of Science ®] [Google Scholar]]’s bias-corrected and accelerated (BCa) bootstrap confidence intervals. In this study, the performances of robust BCa–JaB and conventional JaB methods are compared in the cases of DFFITS, Welsch's distance and modified Cook's distance influence diagnostics. Comparisons are based on both real data examples and through a simulation study. Our results reveal that under a variety of scenarios, our proposed method provides more accurate and reliable results, and it is more robust to masking effects.  相似文献   

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