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1.
Two-period crossover design is one of the commonly used designs in clinical trials. But, the estimation of treatment effect is complicated by the possible presence of carryover effect. It is known that ignoring the carryover effect when it exists can lead to poor estimates of the treatment effect. The classical approach by Grizzle (1965 Grizzle, J.E. (1965). The two-period change-over design and its use in clinical trials. Biometrics 21:467480. See Grizzle (1974) for corrections.[Crossref], [PubMed], [Web of Science ®] [Google Scholar]) consists of two stages. First, a preliminary test is conducted on carryover effect. If the carryover effect is significant, analysis is based only on data from period one; otherwise, analysis is based on data from both periods. A Bayesian approach with improper priors was proposed by Grieve (1985 Grieve, A.P. (1985). A Bayesian analysis of the two-period crossover design for clinical trials. Biometrics 41:979990.[Crossref], [PubMed], [Web of Science ®] [Google Scholar]) which uses a mixture of two models: a model with carryover effect and another without. The indeterminacy of the Bayes factor due to the arbitrary constant in the improper prior was addressed by assigning a minimally discriminatory value to the constant. In this article, we present an objective Bayesian estimation approach to the two-period crossover design which is also based on a mixture model, but using the commonly recommended Zellner–Siow g-prior. We provide simulation studies and a real data example and compare the numerical results with Grizzle (1965 Grizzle, J.E. (1965). The two-period change-over design and its use in clinical trials. Biometrics 21:467480. See Grizzle (1974) for corrections.[Crossref], [PubMed], [Web of Science ®] [Google Scholar])’s and Grieve (1985 Grieve, A.P. (1985). A Bayesian analysis of the two-period crossover design for clinical trials. Biometrics 41:979990.[Crossref], [PubMed], [Web of Science ®] [Google Scholar])’s approaches.  相似文献   

2.
Since the seminal paper of Ghirardato (1997 Ghirardato, P. 1997. On the independence for non-additive measures, with a Fubini theorem. Journal of Economic Theory 73:26191.[Crossref], [Web of Science ®] [Google Scholar]), it is known that Fubini theorem for non additive measures can be available only for functions as “slice-comonotonic” in the framework of product algebra. Later, inspired by Ghirardato (1997 Ghirardato, P. 1997. On the independence for non-additive measures, with a Fubini theorem. Journal of Economic Theory 73:26191.[Crossref], [Web of Science ®] [Google Scholar]), Chateauneuf and Lefort (2008 Chateauneuf, A., and J. P. Lefort. 2008. Some Fubini theorems on product σ-algebras for non-additive measures. International Journal of Approximate Reasoning 48:68696.[Crossref], [Web of Science ®] [Google Scholar]) obtained some Fubini theorems for non additive measures in the framework of product σ-algebra. In this article, we study Fubini theorem for non additive measures in the framework of g-expectation. We give some different assumptions that provide Fubini theorem in the framework of g-expectation.  相似文献   

3.
Let X1, X2, … be a sequence of stationary standardized Gaussian random fields. The almost sure limit theorem for the maxima of stationary Gaussian random fields is established. Our results extend and improve the results in Csáki and Gonchigdanzan (2002 Csáki, E., Gonchigdanzan, K. (2002). Almost sure limit theorems for the maximum of stationary Gaussian sequences. Stat. Probab. Lett. 58:195203.[Crossref], [Web of Science ®] [Google Scholar]) and Choi (2010 Choi, H. (2010). Almost sure limit theorem for stationary Gaussian random fields. J. Korean Stat. Soc. 39:449454.[Crossref], [Web of Science ®] [Google Scholar]).  相似文献   

4.
In this article, we discuss the method of linear kernel quantile estimator proposed by Parzen (1979 Parzen, E. (1979). Nonparametric statistical data modeling. J. Amer. Statist. Assoc. 74:105121.[Taylor &; Francis Online], [Web of Science ®] [Google Scholar]). We establish a Bahadur representation in sense of almost surely convergence with the rate log? αn under the case of S-mixing random variable sequence which was proposed by Berkes (2009 Berkes, I., Hörmann, S., (2009). Asymptotic results for the itpirical process of stationary sequences. Stoch. Process. Their Applic. 119:12981324.[Crossref], [Web of Science ®] [Google Scholar]). We also obtain the strong consistence of this estimator and its convergence rate.  相似文献   

5.
The aim of this article is the construction of the test statistic for the detection of changes in vector autoregressive (AR) models where both AR parameters and the variance matrix of the error term are the subjects of a change. The approximating distribution of the proposed statistic is the Gumbel distribution. The proof stands on the approximation of weakly dependent random vectors by independent ones and by application of Horváth’s extension of Darling-Erdös extremal result for random vectors, see Darling and Erdös (1956) Darling, D.A., Erdös, P. (1956). A limit theorem for the maximum of normalized sums of independent random variables. Duke Math. J. 23:143155.[Crossref], [Web of Science ®] [Google Scholar] and Horváth (1993) Horváth, L. (1993). The maximum likelihood method for testing changes in the parameters of normal observations. Ann. Stat. 21(2):671680.[Crossref], [Web of Science ®] [Google Scholar]. The test statistic is a modification of the likelihood ratio.  相似文献   

6.
The objective of this paper is to study U-type designs for Bayesian non parametric response surface prediction under correlated errors. The asymptotic Bayes criterion is developed in terms of the asymptotic approach of Mitchell et al. (1994 Mitchell, T., Sacks, J., Ylvisaker, D. (1994). Asymptotic Bayes criteria for nonparametric response surface design. Ann. Stat. 22:634651.[Crossref], [Web of Science ®] [Google Scholar]) for a more general covariance kernel proposed by Chatterjee and Qin (2011 Chatterjee, K., Qin, H. (2011). Generalized discrete discrepancy and its applications in experimental designs. J. Stat. Plann. Inference 141:951960.[Crossref], [Web of Science ®] [Google Scholar]). A relationship between the asymptotic Bayes criterion and other criteria, such as orthogonality and aberration, is then developed. A lower bound for the criterion is also obtained, and numerical results show that this lower bound is tight. The established results generalize those of Yue et al. (2011 Yue, R.X., Qin, H., Chatterjee, K. (2011). Optimal U-type design for Bayesian nonparametric multiresponse prediction. J. Stat. Plann. Inference 141:24722479.[Crossref], [Web of Science ®] [Google Scholar]) from symmetrical case to asymmetrical U-type designs.  相似文献   

7.
The mean residual life of a life distribution, X, with a finite mean is defined by M(t) = E[X ? t|X > t] for t ? 0. Kochar et al. (2000 Kochar, S.C., Mukerjee, H., Samaniego, F.J. (2000). Estimation of a monotone mean residual life. Ann. Stat. 28: 905921.[Crossref], [Web of Science ®] [Google Scholar]) provided an estimator of M when it is assumed to be decreasing. They showed that its asymptotic distribution was the same as that of the empirical estimate, but only under very stringent analytic and distributional assumptions. We provide a more general asymptotic theory, and under much weaker conditions. We also provide improved asymptotic confidence bands.  相似文献   

8.
This article is concerned with the minimax estimation of a scale parameter under the quadratic loss function where the family of densities is location-scale type. We obtain results for the case when the scale parameter is bounded below by a known constant. Implications for the estimation of a lower-bounded scale parameter of an exponential distribution are presented under unknown location. Furthermore, classes of improved minimax estimators are derived for the restricted parameter using the Integral Expression for Risk Difference (IERD) approach of Kubokawa (1994 Kubokawa, T. (1994). A unified approach to improving equivariant estimators. Ann. Stat. 22:290299.[Crossref], [Web of Science ®] [Google Scholar]). These classes are shown to include some existing estimators from literature.  相似文献   

9.
Repeated measurement designs are widely used in medicine, pharmacology, animal sciences, and psychology. In this paper the works of Iqbal and Tahir (2009 Iqbal, I., and M. H. Tahir. 2009. Circular strongly balanced repeated measurements designs. Communications in Statistics—Theory and Methods 38:368696.[Taylor &; Francis Online], [Web of Science ®] [Google Scholar]) and Iqbal, Tahir, and Ghazali (2010 Iqbal, I., M. H. Tahir, and S. S. A. Ghazali. 2010. Circular first- and second-order balanced repeated measurements designs. Communications in Statistics—Theory and Methods 39:22840.[Taylor &; Francis Online], [Web of Science ®] [Google Scholar]) are generalized for the construction of circular-balanced and circular strongly balanced repeated measurements designs through the method of cyclic shifts for three periods.  相似文献   

10.
Techniques used in variability assessment are subsequently used to draw conclusions regarding the “spread”/uniformity of data curves. Due to the limitations of these techniques, they are not adequate for circumstances where data manifest with multiple peaks. Examples of these manifestations (in three-dimensional space) include under-foot pressure distributions recorded for different types of footwear (Becerro-de-Bengoa-Vallejo et al., 2014 Biau, D.J. (2011). In brief: Standard deviation and standard error. Clinical Orthopaedics and Related Research 469(9):26612664.[Crossref], [PubMed], [Web of Science ®] [Google Scholar]; Cibulka et al., 1994 Cibulka, M.T., Sinacore, D.R., Mueller, M.J. (1994). Shin splints and forefoot contact running: A case report. Journal of Orthopaedic &; Sports Physical Therapy 20(2):98102.[Crossref], [PubMed], [Web of Science ®] [Google Scholar]; Davies et al., 2003 Davies, M.B., Betts, R.P., Scott, I.R. (2003). Optical plantar pressure analysis following internal fixation for displaced intra-articular os calcis fractures. Foot &; Ankle International 24(11):851856.[PubMed], [Web of Science ®] [Google Scholar]), surface textures and interfaces designed to impact friction, and and and molecular surface structures such as viral epitopes (Torras and Garcia-Valls, 2004 Torras, C., Garcia-Valls, R. (2004). Quantification of membrane morphology by interpretation of scanning electron microscopy images. Journal of Membrane Science 233(1–2):119127.[Crossref], [Web of Science ®] [Google Scholar]; Pacejka, 1997; Fustaffson, 1997). This article proposes a technique for generating a single variable – Λ that will quantify the uniformity of such surfaces. We define and validate this technique using several mathematical and graphical models.  相似文献   

11.
This paper aimed at providing an efficient new unbiased estimator for estimating the proportion of a potentially sensitive attribute in survey sampling. The suggested randomization device makes use of the means, variances of scrambling variables, and the two scalars lie between “zero” and “one.” Thus, the same amount of information has been used at the estimation stage. The variance formula of the suggested estimator has been obtained. We have compared the proposed unbiased estimator with that of Kuk (1990 Kuk, A.Y.C. (1990). Asking sensitive questions inderectely. Biometrika 77:436438.[Crossref], [Web of Science ®] [Google Scholar]) and Franklin (1989 Franklin, L.A. (1989). A comparision of estimators for randomized response sampling with continuous distribution s from a dichotomous population. Commun. Stat. Theor. Methods 18:489505.[Taylor &; Francis Online], [Web of Science ®] [Google Scholar]), and Singh and Chen (2009 Singh, S., Chen, C.C. (2009). Utilization of higher order moments of scrambling variables in randomized response sampling. J. Stat. Plann. Inference. 139:33773380.[Crossref], [Web of Science ®] [Google Scholar]) estimators. Relevant conditions are obtained in which the proposed estimator is more efficient than Kuk (1990 Kuk, A.Y.C. (1990). Asking sensitive questions inderectely. Biometrika 77:436438.[Crossref], [Web of Science ®] [Google Scholar]) and Franklin (1989 Franklin, L.A. (1989). A comparision of estimators for randomized response sampling with continuous distribution s from a dichotomous population. Commun. Stat. Theor. Methods 18:489505.[Taylor &; Francis Online], [Web of Science ®] [Google Scholar]) and Singh and Chen (2009 Singh, S., Chen, C.C. (2009). Utilization of higher order moments of scrambling variables in randomized response sampling. J. Stat. Plann. Inference. 139:33773380.[Crossref], [Web of Science ®] [Google Scholar]) estimators. The optimum estimator (OE) in the proposed class of estimators has been identified which finally depends on moments ratios of the scrambling variables. The variance of the optimum estimator has been obtained and compared with that of the Kuk (1990 Kuk, A.Y.C. (1990). Asking sensitive questions inderectely. Biometrika 77:436438.[Crossref], [Web of Science ®] [Google Scholar]) and Franklin (1989 Franklin, L.A. (1989). A comparision of estimators for randomized response sampling with continuous distribution s from a dichotomous population. Commun. Stat. Theor. Methods 18:489505.[Taylor &; Francis Online], [Web of Science ®] [Google Scholar]) estimator and Singh and Chen (2009 Singh, S., Chen, C.C. (2009). Utilization of higher order moments of scrambling variables in randomized response sampling. J. Stat. Plann. Inference. 139:33773380.[Crossref], [Web of Science ®] [Google Scholar]) estimator. It is interesting to mention that the “optimum estimator” of the class of estimators due to Singh and Chen (2009 Singh, S., Chen, C.C. (2009). Utilization of higher order moments of scrambling variables in randomized response sampling. J. Stat. Plann. Inference. 139:33773380.[Crossref], [Web of Science ®] [Google Scholar]) depends on the parameter π under investigation which limits the use of Singh and Chen (2009 Singh, S., Chen, C.C. (2009). Utilization of higher order moments of scrambling variables in randomized response sampling. J. Stat. Plann. Inference. 139:33773380.[Crossref], [Web of Science ®] [Google Scholar]) OE in practice while the proposed OE in this paper is free from such a constraint. The proposed OE depends only on the moments ratios of scrambling variables. This is an advantage over the Singh and Chen (2009 Singh, S., Chen, C.C. (2009). Utilization of higher order moments of scrambling variables in randomized response sampling. J. Stat. Plann. Inference. 139:33773380.[Crossref], [Web of Science ®] [Google Scholar]) estimator. Numerical illustrations are given in the support of the present study when the scrambling variables follow normal distribution. Theoretical and empirical results are very sound and quite illuminating in the favor of the present study.  相似文献   

12.
Cooray and Ananda (2008 Cooray, K., Ananda, M.M.A. (2008). A Generalization of the half-normal distribution with applications to lifetime data. Commun. Stat. - Theory Methods 37:13231337.[Taylor &; Francis Online], [Web of Science ®] [Google Scholar]) pioneered a lifetime model commonly used in reliability studies. Based on this distribution, we propose a new model called the odd log-logistic generalized half-normal distribution for describing fatigue lifetime data. Various of its structural properties are derived. We discuss the method of maximum likelihood to fit the model parameters. For different parameter settings and sample sizes, some simulation studies compare the performance of the new lifetime model. It can be very useful, and its superiority is illustrated by means of a real dataset.  相似文献   

13.
This paper proposes a bivariate version of the univariate discrete generalized geometric distribution considered by Gómez–Déniz (2010 Gómez–Déniz, E. (2010). Another generalization of the geometric distribution. Test 19:399415.[Crossref], [Web of Science ®] [Google Scholar]). The proposed bivariate distribution can have a positive or negative correlation coefficient which can be used for modeling bivariate-dependent count data. After discussing some of its properties, maximum likelihood estimation is discussed. Two illustrative examples are given for fitting and demonstrating the usefulness of the new bivariate distribution proposed here.  相似文献   

14.
The complication in analyzing tumor data is that the tumors detected in a screening program tend to be slowly progressive tumors, which is the so-called left-truncated sampling that is inherent in screening studies. Under the assumption that all subjects have the same tumor growth function, Ghosh (2008 Ghosh, D. (2008). Proportional hazards regression for cancer studies. Biometrics 64:141148.[Crossref], [PubMed], [Web of Science ®] [Google Scholar]) developed estimation procedures for the Cox proportional hazards model. Shen (2011a Shen, P.-S. (2011a). Proportional hazards regression for cancer screening data. J. Stat. Comput. Simul. 18:367377.[Taylor &; Francis Online], [Web of Science ®] [Google Scholar]) demonstrated that Ghosh (2008 Ghosh, D. (2008). Proportional hazards regression for cancer studies. Biometrics 64:141148.[Crossref], [PubMed], [Web of Science ®] [Google Scholar])'s approach can be extended to the case when each subject has a specific growth function. In this article, under linear transformation model, we present a general framework to the analysis of data from cancer screening studies. We developed estimation procedures under linear transformation model, which includes Cox's model as a special case. A simulation study is conducted to demonstrate the potential usefulness of the proposed estimators.  相似文献   

15.
This paper treats the problem of stochastic comparisons for the extreme order statistics arising from heterogeneous beta distributions. Some sufficient conditions involved in majorization-type partial orders are provided for comparing the extreme order statistics in the sense of various magnitude orderings including the likelihood ratio order, the reversed hazard rate order, the usual stochastic order, and the usual multivariate stochastic order. The results established here strengthen and extend those including Kochar and Xu (2007 Kochar, S.C., Xu, M. (2007). Stochastic comparisons of parallel systems when components have proportional hazard rates. Probab. Eng. Inf. Sci. 21:597609.[Crossref], [Web of Science ®] [Google Scholar]), Mao and Hu (2010 Mao, T., Hu, T. (2010). Equivalent characterizations on orderings of order statistics and sample ranges. Probab. Eng. Inf. Sci. 24:245262.[Crossref], [Web of Science ®] [Google Scholar]), Balakrishnan et al. (2014 Balakrishnan, N., Barmalzan, G., Haidari, A. (2014). On usual multivariate stochastic ordering of order statistics from heterogeneous beta variables. J. Multivariate Anal. 127:147150.[Crossref], [Web of Science ®] [Google Scholar]), and Torrado (2015 Torrado, N. (2015). On magnitude orderings between smallest order statistics from heterogeneous beta distributions. J. Math. Anal. Appl. 426:824838.[Crossref], [Web of Science ®] [Google Scholar]). A real application in system assembly and some numerical examples are also presented to illustrate the theoretical results.  相似文献   

16.
Filipiak and Markiewicz (2012 Filipiak, K., Markiewicz, A. (2012). On universal optimality of circular weakly neighbor balanced designs under an interference model. Comm. Stat. Theor Methods 41: 23562366.[Taylor &; Francis Online], [Web of Science ®] [Google Scholar]) proved the universal optimality of circular weakly neighbor balanced designs (CWNBDs) under the interference model with fixed neighbor effects among the class of complete block designs. In two special cases where a CWNBD cannot exist, Filipiak et al. (2012 Filipiak, K., Markiewicz, A., Ró?ański, R. (2012). Maximal determinant over a certain class of matrices and its application to D-optimality of designs. Linear Algebra Appl. 436(4): 874887.[Crossref], [Web of Science ®] [Google Scholar]) characterized D-optimal designs. The aim of this paper is to show the universal optimality of CWNBDs and to characterize D-optimal designs under the interference model with random neighbor effects.  相似文献   

17.
Gupta and Kirmani (2008 Gupta, R.C., Kirmani, S.N.U.A. (2008). Characterization based on convex conditional mean function. J. Stat. Plann Inference. 138:964970.[Crossref], [Web of Science ®] [Google Scholar]) showed that the convex conditional mean function (CCMF) characterizes the distribution function completely. In this paper, we introduce a consistent estimator of CCMF and call it empirical convex conditional mean function (ECCMF). Then we construct a simple consistent test of fit based on the integrated squared difference between ECCMF and CCMF. The theoretical and asymptotic properties of the estimator ECCMF and the proposed test statistic are studied. The performance of the constructed test is investigated under different distributions using simulations.  相似文献   

18.
Cossette et al. (2010 Cossette, H., Marceau, E., Maume-Deschamps, V. (2010). Discerte-time risk models based on time series for count random variables. ASTIN Bull. 40:123150.[Crossref], [Web of Science ®] [Google Scholar], 2011 Cossette, H., Marceau, E., Toureille, F. (2011). risk models based on time series for count random variables. Insur. Math. Econ. 48:1928.[Crossref], [Web of Science ®] [Google Scholar]) gave a novel collective risk model where the total numbers of claims satisfy the first-order integer-valued autoregressive process. For a risk model, it is interesting to investigate the upper bound of ruin probability. However, the loss increments of the above model are dependent; it is difficult to derive the upper bound of ruin probability. In this article, we propose an approximation model with stationary independent increments. The upper bound of ruin probability and the adjustment coefficient are derived. The approximation model is illustrated via four simulated examples. Results show that the gap of the approximation model and dependent model can be ignored by adjusting values of parameters.  相似文献   

19.
In this article, we establish the complete moment convergence of a moving-average process generated by a class of random variables satisfying the Rosenthal-type maximal inequality and the week mean dominating condition. On the one hand, we give the correct proof for the case p = 1 in Ko (2015 Ko, M.H. (2015). Complete moment convergence of moving average process generated by a class of random variables. J. Inequalities Appl. 2015(1):19. Article ID 225.[Crossref], [Web of Science ®] [Google Scholar]); on the other hand, we also consider the case αp = 1 which was not considered in Ko (2015 Ko, M.H. (2015). Complete moment convergence of moving average process generated by a class of random variables. J. Inequalities Appl. 2015(1):19. Article ID 225.[Crossref], [Web of Science ®] [Google Scholar]). The results obtained in this article generalize some corresponding ones for some dependent sequences.  相似文献   

20.
Credibility formula has been developed in many fields of actuarial sciences. Based upon Payandeh (2010 Payandeh, A.T. (2010). A new approach to the credibility formula. Insur.: Math. Econ. 46(2):334338.[Crossref], [Web of Science ®] [Google Scholar]), this article extends concept of credibility formula to relatively premium of a given rate-making system. More precisely, it calculates Payandeh’s (2010 Payandeh, A.T. (2010). A new approach to the credibility formula. Insur.: Math. Econ. 46(2):334338.[Crossref], [Web of Science ®] [Google Scholar]) credibility factor for zero-inflated Poisson gamma distributions with respect to several loss functions. A comparison study has been given.  相似文献   

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