“U.S. Pharmaceutical Gray Markets: Why Do They Persist—and What to Do about Them?”

This article illustrates how a traditional U.S. pharmaceutical industry supply chain operates, beginning with pharmaceutical compounds and ending at patient‐dispensing hospitals or pharmacies. Furthermore, to place the problem of U.S. drug shortages in historical perspective, a review of the annual volume of such shortages over the last decade is undertaken. Following this review of recent drug shortages is an analysis of the market forces and business decisions that drive the creation of a pharmaceutical gray market, its attendant “price gouging” and product integrity issues, and the alterations in the traditional pharmaceutical industry supply chain model. In response to persistent drug shortages, the U.S. Food and Drug Administration (FDA) has recently been empowered by the executive and legislative branches of the U.S. government to actively address this issue. To reflect these FDA challenges, a thorough review of these new agency charges and responsibilities is undertaken. Lastly, an analysis of the results of recent FDA public policy actions on mitigating drug shortages, as well as recommendations tor market‐based solutions to the gray market problem that pharmaceutical manufacturers, hospitals and pharmacies could institute as industry‐wide standards of business practice, are discussed in the conclusion.     

Decision Making and Cognition in Multi‐Echelon Supply Chains: An Experimental Study

Supply chain performance often depends on the individual decisions of channel members. Even when individuals have access to relevant information, order variation tends to increase when moving up the supply chain, a phenomenon known as the bullwhip effect. While prior research has investigated several structural/environmental factors which can mitigate the bullwhip effect, the underlying behavioral factors contributing to it are an open question. Using a production and distribution decision‐making simulation representing a four‐stage serial supply chain, we find that the cognitive profile of decision makers contributes to the bullwhip effect. We found that the specific decision tendency to underweight the supply line is linked to an individual's level of cognitive reflection. Furthermore, performance differs for entire supply chains and for specific echelons, and holds under standard mitigation efforts. The findings have implications for supply chain design, education, and industry.     

Push and Pull Contracts in a Local Supply Chain with an Outside Market*

Wholesale price contracts are widely studied in a single supplier‐single retailer supply chain, but without considering an outside market where the supplier may sell if he gets a high enough price and the retailer may buy if the price is low enough. We fill this gap in the literature by studying push and pull contracts in a local supplier–retailer supply chain with the presence of an outside market. Taking the local supplier's maximum production capacity and the outside market barriers into account, we identify the Pareto set of the push and/or pull contracts and draw managerial implications. The main results include the following. First, the most inefficient point of the pull Pareto set cannot always be removed by considering both the push and pull contracts. Second, the supplier's production capacity plays a significant role in the presence of an outside market; it affects the supplier's negotiating power with the retailer and the coordination of the supply chain can be accomplished only with a large enough capacity. Third, the import and export barriers influence the supply chain significantly: (i) an export barrier in the local market and the supplier's production capacity influence the supplier's export strategy; (ii) a low import (resp., export) barrier in the local market can improve the local supply chain's efficiency by use of a push (resp., pull) contract; and (iii) a high import (resp., export) barrier in the local market encourages the supplier (resp., retailer) to bear more inventory risk.     

Supply Chain Coordination in the Presence of Gray Markets and Strategic Consumers

The practice of diverting genuine products to unauthorized gray markets continues to challenge companies in various industries and creates intense competition for authorized channels. Recent industry surveys report that the abuse of channel incentives is a primary reason for the growth of gray market activities. Therefore, it is crucial that companies take the presence of gray markets into consideration when they design contracts to distribute products through authorized retailers. This issue has received little attention in the extensive literature on contracting and supply chain coordination. In this study, we analyze the impacts of gray markets on two classic contracts, wholesale price and quantity discount, in a supply chain with one manufacturer and one retailer when the retailer has the opportunity to sell to a domestic gray market. Our analysis provides interesting and counterintuitive results. First, a classic quantity‐discount contract that normally coordinates the supply chain can perform so poorly in the presence of a gray market that the supply chain would be better off using a wholesale price contract instead. Second, the presence of gray market can also degrade the performance of the wholesale price contract; therefore, a more sophisticated contract is needed for coordinating the supply chain. We show that contracts that solely depend on retailer's order quantity cannot coordinate the supply chain, and provide the conditions for coordinating the supply chain with price‐dependent quantity discount contracts. We also provide comparative statics and show that when there is a gray market, coordinating the supply chain enhances total consumer welfare.     

Competition and Coordination in a Two‐Channel Supply Chain

We study competition and coordination in a supply chain in which a single supplier both operates a direct channel and sells its product through multiple differentiated retailers. We study analytically the supply chain with symmetric retailers and find that the supplier prefers to have as many retailers as possible in the market, even if the retailers' equilibrium retail price is lower than that of the supplier, and even if the number of retailers and their cost or market advantage prevent sales through the direct channel. We find that the two‐channel supply chain may be subject to inefficiencies not present in the single‐channel supply chain. We show that several contracts known to coordinate a single‐channel supply chain do not coordinate the two‐channel supply chain; thus we propose a linear quantity discount contract and demonstrate its ability to perfectly coordinate the two‐channel supply chain with symmetric retailers. We provide some analytical results for the supply chain with asymmetric retailers and propose an efficient solution approach for finding the equilibrium. We find numerically that the supplier still benefits from having more retailers in the market and that linear quantity discount contracts can mitigate supply chain inefficiency, though they no longer achieve perfect coordination.     

The Agency Model for Digital Goods

While digital goods industries such as entertainment, software, and publishing are growing at a rapid pace, traditional supply chain contract models have failed to evolve with the new digital economy. To illustrate, the agency model utilized by the e‐book publishing industry has recently received much negative attention brought by the U.S. Department of Justice's lawsuit against Apple, Inc. The emerging agency model in the e‐book industry works as follows: the publisher sets the price of the digital goods and the retailers who serve as agents retain a percentage of the revenue associated with a consumer purchase. The regulators claim that the agency model is hurting this industry as well as the consumer's welfare because e‐book prices have increased after the introduction of the agency model. We investigate the strategic impact of the agency model by examining a digital goods supply chain with one supplier and two competing retailers. In comparison to the benchmark wholesale model, we find that the agency model can coordinate the competing retailers by dividing the coordinated profits into a prenegotiated revenue sharing proportion. Further, we also identify the Pareto improving region whereby both the supplier and the retailers prefer the agency model to the wholesale model. Our main qualitative insight regarding the agency model still holds even when we consider the presence of the printed books in the marketplace. Thus, contrary to current press presaging the negative impact of the agency model on the e‐books industry, we find the agency model to be superior to the traditional wholesale contracts for publishers, retailers and consumers in this digital goods industry.     

基于需求信息更新和短缺量延期供给的易逝品供应链期权契约研究

为了降低供给与需求的不匹配,引入期权契约讨论三阶段生产和订购策略:零售商在第1阶段发出固定订单;然后在第1阶段和第2阶段之间更新需求预测,并在第2阶段调整固定订购量同时购买期权;第3阶段满足市场需求,对销售季末短缺量以执行期权和紧急订购相结合的方式实行延期供给。契约参数包含期权购买价格、执行价格和延期供给对应的批发价,三者线性相关;期权契约下,制造商不存在投机动力。根据易逝品的特征,对生产和订购模型进行仿真计算和分析,结果表明:供应链及其成员的利润都得到帕累托改进,系统利润增量的分配随期权购买价格发生变化。     

制造商流程改进与采购合同联合优化

如何降低供应风险是供应链管理中的热点问题。本文考虑供应商拥有关于初始可靠性的私有信息,且制造商流程改进可提高初始可靠性,运用委托代理理论,研究了制造商流程改进和采购策略联合优化下的最优合同设计。通过对比对称和不对称信息下制造商的最优采购合同,发现信息不对称的存在降低了制造商向低初始可靠性供应商订货的概率,还可能导致过度努力。信息不对称的存在不一定造成社会福利损失,也不一定产生信息租金。当供应商的初始可靠性水平和纳什谈判力满足一定条件时,相比与制造商的最优采购合同,供应商披露私有信息会使供应链实现帕累托改进。最后通过算例验证了模型的结论。本文对供应风险下的采购实践有很好的参考价值和指导意义。     

The Role of Contract Negotiation and Industry Structure in Production Outsourcing

Despite the spread of cost‐driven outsourcing practices, academic research cautions that suppliers' cost advantage may weaken manufacturers' bargaining positions in negotiating outsourcing agreements, thereby hurting their profitability. In this study, we attempt to further understand the strategic impact of low‐cost outsourcing on manufacturers' profitability by investigating the contractual form of outsourcing agreements and the industry structure of the upstream supply market. We consider a two‐tier supply chain system, consisting of two competing manufacturers, who have the option to produce in‐house or to outsource to an upstream supplier with lower cost. To reach an outsourcing agreement, each manufacturer engages in bilateral negotiation with her supplier, who may be an exclusive supplier or a common supplier serving both manufacturers. Our analysis shows that wholesale‐price contracts always mitigate the competition between manufacturers regardless of whether they compete with price or quantity. In contrast, two‐part tariffs intensify the competition when the manufacturers compete with quantity, but soften it when they compete with price. As a result, when outsourcing with two‐part tariffs, the manufacturers may earn lower profits than they would from in‐house production, although the suppliers are more cost efficient. This suggests that managers have to be wary about the downside of using coordinating contracts such as two‐part tariffs when pursuing low‐cost outsourcing strategies. Our analysis also sheds some light on the profitability of using an exclusive supplier for outsourcing. When outsourcing with wholesale‐price contracts, the competing manufacturers are better off outsourcing to an exclusive supplier. However, when outsourcing with two‐part tariffs, the manufacturers may earn higher profits by outsourcing to a common supplier than to an exclusive one when the manufacturers' bargaining power is sufficiently strong (weak) under quantity (price) competition.     

Supply chain coordination with information design

We consider the coordination of a supplier–retailer supply chain where, in addition to classical contract considerations, a supplier decides the adoption of an information structure (IS) for the supply chain, with a higher-quality IS allowing the supply chain parties to obtain a more accurate demand forecast. Because a wholesale price contract cannot coordinate the supply chain due to misaligned incentives of supply chain parties, we explore what common coordinating contracts in the classical coordination literature can continue coordinating the supply chain with the IS adoption. Interestingly, our analysis appears to reveal the power of simplicity: some simple classical coordinating contracts (e.g., the buy-back and revenue-sharing contracts), though not designed with the IS consideration, still coordinate the supply chain, whereas other more complicated classical contracts (e.g., the quantity flexibility and sales rebate contracts) fail to do so. We derive a general condition for supply chain coordination and show that any contract with a newsvendor-like transfer payment can coordinate the supply chain.     

基于CVaR的供应链联合促销的回购契约协调研究

运用CVaR方法,考察了风险中性的供应商和风险规避的销售商联合促销报童类商品的供应链的回购契约协调问题,从讨论中获得一些管理启示。讨论了既定回购契约下渠道成员的最优决策,并分析了回购契约参数、销售商风险规避系数、商品残值和缺货成本等外生参数对渠道成员决策的影响。研究表明传统回购契约不能完成渠道协调,但引入成本分担机制的回购契约能协调不过于规避风险的供应链;指出商品残值和缺货成本对上述结论没有影响,但它们对契约选择空间和能被回购契约协调的供应链的范围具有重要影响。最后,对文中主要结论进行了数值分析。     

Traceability and Risk Analysis Strategies for Addressing Counterfeit Electronics in Supply Chains for Complex Systems

Within the microelectronics industry, there is a growing concern regarding the introduction of counterfeit electronic parts into the supply chain. Even though this problem is widespread, there have been limited attempts to implement risk‐based approaches for testing and supply chain management. Supply chain risk management tends to focus on the highly visible disruptions of the supply chain instead of the covert entrance of counterfeits; thus counterfeit risk is difficult to mitigate. This article provides an overview of the complexities of the electronics supply chain, and highlights some gaps in risk assessment practices. In particular, this article calls for enhanced traceability capabilities to track and trace parts at risk through various stages of the supply chain. Placing the focus on risk‐informed decision making through the following strategies is needed, including prioritization of high‐risk parts, moving beyond certificates of conformance, incentivizing best supply chain management practices, adoption of industry standards, and design and management for supply chain resilience.     

Designing Supply Contracts Considering Profit Targets and Risk

Managers at all stages of a supply chain are concerned about meeting profit targets. We study contract design for a buyer–supplier supply chain, with each party maximizing expected profit subject to a chance constraint on meeting his respective profit target. We derive the optimal contract form (across all contract types) with randomized and deterministic payments. The best contract has the property that, if the chance constraints are binding, at most one party fails to satisfy his profit target for any given demand realization. This implies that “least risk sharing,”that is, minimizing the probability of outcomes for which both parties fail to achieve their profit targets, is optimal, contrary to the usual expectations of “risk sharing.” We show that an optimal contract can possess only two of the following three properties simultaneously: (i) supply chain coordination, (ii) truth‐telling, and (iii) non‐randomized payments. We discuss methods to mitigate the consequent implementation challenges. We also derive the optimal contract form when chance constraints are incorporated into several simpler and easier‐to‐implement contracts. From a numerical study, we find that an incremental returns contract (in which the marginal rebate rate depends on the return quantity) performs quite well across a relatively broad range of conditions.     

Outsourcing vs. in-house production: a comparison of supply chain contracts with effort dependent demand

We analyze the effort and pricing decisions in a two facility supply chain in which one of the parties can exert costly effort to increase demand. We consider an outsourcing model in which the supplier makes the effort decision and an in-house production model in which the manufacturer decides on the effort level and we compare these two models with each other. We analyze and compare several contracts for decentralized supply chain models and we aim to find which contracts are best to use in different cases. We find the optimal contract parameters in each case and perform extensive computational testing to compare the efficiencies of these contracts. We also analyze the effect of the powers of the parties in the system and the effect of system parameters on the performances of the contracts and on the optimal values of the model variables such as price, effort and demand.     

Coordination of Supply Chains with Risk‐Averse Agents

The extant supply chain management literature has not addressed the issue of coordination in supply chains involving risk‐averse agents. We take up this issue and begin with defining a coordinating contract as one that results in a Pareto‐optimal solution acceptable to each agent. Our definition generalizes the standard one in the risk‐neutral case. We then develop coordinating contracts in three specific cases: (i) the supplier is risk neutral and the retailer maximizes his expected profit subject to a downside risk constraint; (ii) the supplier and the retailer each maximizes his own mean‐variance trade‐off; and (iii) the supplier and the retailer each maximizes his own expected utility. Moreover, in case (iii), we show that our contract yields the Nash Bargaining solution. In each case, we show how we can find the set of Pareto‐optimal solutions, and then design a contract to achieve the solutions. We also exhibit a case in which we obtain Pareto‐optimal sharing rules explicitly, and outline a procedure to obtain Pareto‐optimal solutions.     

The Impact of Information Sharing and Advance Order Information on a Supply Chain with Balanced Ordering

This paper considers a supply chain with one supplier and multiple retailers that face exogenous heterogeneous end‐customer demands, where all parties utilize base‐stock policies. Each retailer is restricted to order once in every order cycle and their orders are replenished in a balanced manner within the cycle. Our study investigates the impact of information sharing and advance order information (AOI) on the supply chain. We find that the supplier benefits from the two mechanisms via two important factors, the information about observed end‐customer demands and the decision on re‐establishing the replenishment sequence. We derive the supplier's optimal sequence for stochastically comparable end‐customer demands with AOI and propose a sequencing rule for the setting with information sharing. Our numerical study examines the cost impacts of two proposed mechanisms on the entire supply chain.     

Coordinated Contract Decisions in a Make‐to‐Order Manufacturing Supply Chain: A Stochastic Programming Approach

One of the important objectives of supply chain S&OP (Sales and Operations Planning) is the profitable alignment of customer demand with supply chain capabilities through the coordinated planning of sales, production, distribution, and procurement. In the make‐to‐order manufacturing context considered in this paper, sales plans cover both contract and spot sales, and procurement plans require the selection of supplier contracts. S&OP decisions also involve the allocation of capacity to support sales plans. This article studies the coordinated contract selection and capacity allocation problem, in a three‐tier manufacturing supply chain, with the objective to maximize the manufacturer's profitability. Using a modeling approach based on stochastic programming with recourse, we show how these S&OP decisions can be made taking into account economic, market, supply, and system uncertainties. The research is based on a real business case in the Oriented Strand Board (OSB) industry. The computational results show that the proposed approach provides realistic and robust solutions. For the case considered, the planning method elaborated yields significant performance improvements over the solutions obtained from the mixed integer programming model previously suggested for S&OP.     

考虑技术研发和物流配送的医药供应链组合契约协调模型研究

两票制政策的实施使医药供应链管理模式发生了重大变化,也使供应链成员的决策更加复杂。为了确保药品高效、及时、持续的供应,本文研究由一个医药生产企业、一个医药流通企业和一个药店/医院组成的三级供应链的医药定价与协调问题。考虑市场需求受医药生产企业的技术研发和医药流通企业的物流配送影响的情况下,以合作决策的市场价格和最优利润为基准,采用收益共享+数量折扣组合契约作为激励机制,建立了分散决策下供应链组合契约协调模型,探究技术研发和物流配送能力对医药供应链及成员的影响。通过算例分析发现：实施收益共享+数量折扣组合契约策略可以有效的优化和协调医药供应链,能够激励医药生产企业努力提升技术研发水平,激励医药流通企业努力提升物流水平,实现整个医药供应链的帕累托最优。     

Supply chain coordination using revenue-dependent revenue sharing contracts

A typical single period revenue sharing contract specifies a priori a fixed fraction for the supply chain revenue to be shared among the supply chain players. Over the years, supply chains, especially in the movie industry, have adopted multi-period revenue sharing contracts that specify one fraction for each contract period. These revenue sharing contracts are of revenue-independent type such that the revenue sharing fractions are independent of the quantum of revenue generated. Motivated by the recent events in Bollywood – one of the popular arms of the Indian movie industry – in this paper we develop and analyze a game theoretic model for revenue-dependent revenue sharing contracts wherein the actual proportion in which the supply chain revenue is shared among the players depends on the quantum of revenue generated. Our aim is to understand why revenue-dependent revenue sharing contracts are (or not) preferred over revenue-independent contracts. We also examine if supply chains can be coordinated over multiple periods using both types of revenue sharing contracts. We build a two-period model characterizing supply chains in the movie industry and highlight the implications of the multi-period contractual setting for the supply chain coordinating revenue sharing contracts. We show that supply chains can be perfectly coordinated using both types of revenue sharing contracts; however, there exist situations in which revenue-dependent contracts outperform revenue-independent contracts. Using revenue-dependent revenue sharing contracts supply chains can be coordinated while providing positive surplus to the supply chain players that is otherwise not possible under certain situations in revenue-independent contracts. We also demonstrate how revenue-dependent contracts enhance supply chain coordination and highlight their significance when the drop in the revenue potential from one period to another is moderate.     

The Role of Slotting Fees in the Coordination of Assortment Decisions

Large numbers of new products introduced annually by manufacturers may strain the relationship between retailers and manufacturers regarding assortments carried by retailers. For example, many retailers in the grocery industry will agree to broaden their assortments only if the manufacturer agrees to pay slotting fees for the new products. We investigate the role played by slotting fees in coordinating the assortment decisions in a supply chain. To do so, we study a single‐retailer, single‐manufacturer supply chain, where the retailer decides what assortment to offer to end customers. Double marginalization results in a discrepancy between the retailer's optimal assortment and the assortment that maximizes total supply chain profits. We consider a payment scheme that is analogous to slotting fees used in the grocery industry: the manufacturer pays the retailer a per‐product fee for every product offered by the retailer in excess of a certain target level. We show that, if the wholesale price is below some threshold level, this payment scheme induces the retailer to offer the supply‐chain‐optimal assortment and makes both parties better off.