Hypothesis testing in log-Birnbaum-Saunders regressions

The log-Birnbaum-Saunders regression model introduced by Rieck and Nedelman (1991 Rieck, J. R., Nedelman, J. R. (1991). A log-linear model for the Birnbaum-Saunders distribution. Technometrics 33:51–60. [Google Scholar]) is useful for modeling lifetimes of materials and equipments subject to different conditions. Our goal in this article is twofold. First, we numerically evaluate the finite sample performances of the likelihood ratio, score and Wald tests in the log-Birnbaum-Saunders regression model. Second, we introduce a RESET-like misspecification test for that model. The null hypothesis is that the model is correctly specified which is tested against the alternative hypothesis of model misspecification. The power of the test is evaluated using Monte Carlo simulations. Bootstrap-based inference is also considered. An empirical application is presented and discussed.     

Hypotheses Testing on a Multivariate Null Intercept Errors-in-Variables Model

Considering the Wald, score, and likelihood ratio asymptotic test statistics, we analyze a multivariate null intercept errors-in-variables regression model, where the explanatory and the response variables are subject to measurement errors, and a possible structure of dependency between the measurements taken within the same individual are incorporated, representing a longitudinal structure. This model was proposed by Aoki et al. (2003b Aoki , R. , Bolfarine , H. , Achcar , J. A. , Pinto Jr. , D. L. ( 2003b ). Bayesian analysis of a multivariate null intercept errors-in-variables regression model . Journal of Biopharmaceutical Statistics 13 : 767 – 775 .[Taylor & Francis Online] , [Google Scholar]) and analyzed under the bayesian approach. In this article, considering the classical approach, we analyze asymptotic test statistics and present a simulation study to compare the behavior of the three test statistics for different sample sizes, parameter values and nominal levels of the test. Also, closed form expressions for the score function and the Fisher information matrix are presented. We consider two real numerical illustrations, the odontological data set from Hadgu and Koch (1999 Hadgu , A. , Koch , G. ( 1999 ). Application of generalized estimating equations to a dental randomized clinical trial . Journal of Biopharmaceutical Statistics 9 ( 1 ): 161 – 178 .[Taylor & Francis Online] , [Google Scholar]), and a quality control data set.     

Comparison of Frailty Models for Acute Leukemia Data under Gompertz Baseline Distribution

In this article, we consider two different shared frailty regression models under the assumption of Gompertz as baseline distribution. Mostly assumption of gamma distribution is considered for frailty distribution. To compare the results with gamma frailty model, we consider the inverse Gaussian shared frailty model also. We compare these two models to a real life bivariate survival data set of acute leukemia remission times (Freireich et al., 1963 Freireich, E.J., Gehan, E., Frei, E., Schroeder, L.R., Wolman, I.J., Anbari, R., Burgert, E.O., Mills, S.D., Pinkel, D., Selawry, O.S., Moon, J.H., Gendel, B.R., Spurr, C.L., Storrs, R., Haurani, F., Hoogstraten, B., Lee, S. (1963). The effect of 6-mercaptopurine on the duration of steroid-induced remissions in acute leukemia: a model for evaluation of other potentially useful therapy. Blood 21:699–716.[Web of Science ®] , [Google Scholar]). Analysis is performed using Markov Chain Monte Carlo methods. Model comparison is made using Bayesian model selection criterion and a well-fitted model is suggested for the acute leukemia data.     

Population Attributable Fraction as a Measure of Heritability in Dichotomous Twin Data

In many genetic analyses of dichotomous twin data, odds ratios have been used to test hypotheses on heritability and shared common environment effects of a given disease (Lichtenstein et al., 2000 Lichtenstein , P. , Holm , N. , Verkasalo , P. , Iliadou , A. , Kaprio , J. , Koskenvuo , M. , Pukkala , E. , Skytthe , A. , Hemminki , K. ( 2000 ). Environmental and heritable factors in the causation of cancer . New England Journal of Medicine 343 : 78 – 85 .[Crossref], [Web of Science ®] , [Google Scholar]; Ahlbom et al., 1997 Ahlbom , A. , Lichtenstein , P. , Malmström , H. , Feychting , M. , Hemminki , K. , Pedersen , N. L. ( 1997 ). Cancer in twins: genetic and nongenetic familial risk factors . Journal of the National Cancer Institute 89 : 287 – 93 . [Google Scholar]; Ramakrishnan et al., 1992 Ramakrishnan , V. , Goldberg , J. , Henderson , W. , Elsen , S. , True , W. , Lyons , M. , Tsuang , M. ( 1992 ). Elementary methods for the analysis of dichotomous outcomes in unselected samples of twins . Genetic Epidemiology 9 : 273 – 287 . [Google Scholar], 4). However, estimates of these two effects have not been dealt with in the literature. In epidemiology, the attributable fraction (AF), a function of the odds ratio and the prevalence of the risk factor has been used to describe the contribution of a risk factor to a disease in a given population (Leviton, 1973 Leviton , A. ( 1973 ). Definitions of attributable risk . American Journal of Epidemiology 98 : 231 . [Google Scholar]). In this article, we adapt the AF to quantify the heritability and the shared common environment. Twin data on cancer, gallstone disease and phobia are used to illustrate the applicability of the AF estimate as a measure of heritability.     

Selection of Binary Variables and Classification by Boosting

We adopt boosting for classification and selection of high-dimensional binary variables for which classical methods based on normality and non singular sample dispersion are inapplicable. Boosting seems particularly well suited for binary variables. We present three methods of which two combine boosting with the relatively classical variable selection methods developed in Wilbur et al. (2002 Wilbur , J. D. , Ghosh , J. K. , Nakatsu , C. H. , Brouder , S. M. , Doerge , R. W. ( 2002 ). Variable selection in high-dimensional multivariate binary data with application to the analysis of microbial community DNA fingerprints . Biometrics 58 : 378 – 386 . [Google Scholar]). Our primary interest is variable selection in classification with small misclassification error being used as validation of proposed method for variable selection. Two of the new methods perform uniformly better than Wilbur et al. (2002 Wilbur , J. D. , Ghosh , J. K. , Nakatsu , C. H. , Brouder , S. M. , Doerge , R. W. ( 2002 ). Variable selection in high-dimensional multivariate binary data with application to the analysis of microbial community DNA fingerprints . Biometrics 58 : 378 – 386 . [Google Scholar]) in one set of simulated and three real life examples.     

A Comparison of Procedures for Controlling the False Discovery Rate in the Presence of Small Variance Genes: A Simulation Study

The Significance Analysis of Microarrays (SAM; Tusher et al., 2001 Tusher , V. G. , Tibshirani , R. , Chu , G. ( 2001 ). Significance analysis of microarrys applied to the ionizing radiation response . Proceedings of the National Academy of Sciences 98 : 5116 – 5121 .[Crossref], [PubMed], [Web of Science ®] , [Google Scholar]) method is widely used in analyzing gene expression data while controlling the FDR by using resampling-based procedure in the microarray setting. One of the main components of the SAM procedure is the adjustment of the test statistic. The introduction of the fudge factor to the test statistic aims at deflating the large value of test statistics due to the small standard error of gene-expression. Lin et al. (2008 Lin , D. , Shkedy , Z. , Burzykowski , T. , Göhlmann , H. W. H. , De Bondt , A. , Perera , T. , Geerts , T. , Bijnens , L. ( 2008 ). Significance analysis of microarray (SAM) for comparisons of several treatments with one control . Biometric Journal, MCP 50 ( 5 ): 801 – 823 .[Crossref], [PubMed], [Web of Science ®] , [Google Scholar]) pointed out that the fudge factor does not effectively improve the power and the control of the FDR as compared to the SAM procedure without the fudge factor in the presence of small variance genes. Motivated by the simulation results presented in Lin et al. (2008 Lin , D. , Shkedy , Z. , Burzykowski , T. , Göhlmann , H. W. H. , De Bondt , A. , Perera , T. , Geerts , T. , Bijnens , L. ( 2008 ). Significance analysis of microarray (SAM) for comparisons of several treatments with one control . Biometric Journal, MCP 50 ( 5 ): 801 – 823 .[Crossref], [PubMed], [Web of Science ®] , [Google Scholar]), in this article, we extend our study to compare several methods for choosing the fudge factor in the modified t-type test statistics and use simulation studies to investigate the power and the control of the FDR of the considered methods.     

Marginal correlation from an extended random-effects model for repeated and overdispersed counts

Vangeneugden et al. [15 Vangeneugden, T., Molenberghs, G., Laenen, A., Geys, H., Beunckens, C. and Sotto, C. 2007. Marginal correlation in longitudinal binary data based on generalized linear mixed models, Tech. Rep., Hasselt University. submitted for publication [Google Scholar]] derived approximate correlation functions for longitudinal sequences of general data type, Gaussian and non-Gaussian, based on generalized linear mixed-effects models (GLMM). Their focus was on binary sequences, as well as on a combination of binary and Gaussian sequences. Here, we focus on the specific case of repeated count data, important in two respects. First, we employ the model proposed by Molenberghs et al. [13 Molenberghs, G., Verbeke, G. and Demétrio, C. G.B. 2007. An extended random-effects approach to modeling repeated, overdispersed count data. Lifetime Data Anal., 13: 513–531. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]], which generalizes at the same time the Poisson-normal GLMM and the conventional overdispersion models, in particular the negative-binomial model. The model flexibly accommodates data hierarchies, intra-sequence correlation, and overdispersion. Second, means, variances, and joint probabilities can be expressed in closed form, allowing for exact intra-sequence correlation expressions. Next to the general situation, some important special cases such as exchangeable clustered outcomes are considered, producing insightful expressions. The closed-form expressions are contrasted with the generic approximate expressions of Vangeneugden et al. [15 Vangeneugden, T., Molenberghs, G., Laenen, A., Geys, H., Beunckens, C. and Sotto, C. 2007. Marginal correlation in longitudinal binary data based on generalized linear mixed models, Tech. Rep., Hasselt University. submitted for publication [Google Scholar]]. Data from an epileptic-seizures trial are analyzed and correlation functions derived. It is shown that the proposed extension strongly outperforms the classical GLMM.     

Some tests for the allometric extension model in regression

The allometric extension model is a multivariate regression model recently proposed by Tarpey and Ivey (2006 Tarpey, T., Ivey, C.T. (2006). Allometric extension for multivariate regression. J. Data Sci. 4:479–495. [Google Scholar]). This model holds when the matrix of covariances between the variables in the response vector y and the variables in the vector of regressors x has a particular structure. In this paper, we consider tests of hypotheses for this structure when (y′, x′)′ has a multivariate normal distribution. In particular, we investigate the likelihood ratio test and a Wald test.     

Random Effects,Fixed Effects and Hausman's Test for the Generalized Mixed Regressive Spatial Autoregressive Panel Data Model

This article suggests random and fixed effects spatial two-stage least squares estimators for the generalized mixed regressive spatial autoregressive panel data model. This extends the generalized spatial panel model of Baltagi et al. (2013 Baltagi, B. H., Egger, P., Pfaffermayr, M. (2013). A generalized spatial panel data model with random effects. Econometric Reviews 32:650–685.[Taylor &; Francis Online], [Web of Science ®] , [Google Scholar]) by the inclusion of a spatial lag term. The estimation method utilizes the Generalized Moments method suggested by Kapoor et al. (2007 Kapoor, M., Kelejian, H. H., Prucha, I. R. (2007). Panel data models with spatially correlated error components. Journal of Econometrics 127(1):97–130.[Crossref], [Web of Science ®] , [Google Scholar]) for a spatial autoregressive panel data model. We derive the asymptotic distributions of these estimators and suggest a Hausman test a la Mutl and Pfaffermayr (2011 Mutl, J., Pfaffermayr, M. (2011). The Hausman test in a Cliff and Ord panel model. Econometrics Journal 14:48–76.[Crossref], [Web of Science ®] , [Google Scholar]) based on the difference between these estimators. Monte Carlo experiments are performed to investigate the performance of these estimators as well as the corresponding Hausman test.     

Estimating Incidence Rate on Current Status Data with Application to a Phase IV Cancer Trial

New drug discovery in the pediatrics has dramatically improved survival, but with long- term adverse events. This motivates the examination of adverse outcomes such as long-term toxicity in a phase IV trial. An ideal approach to monitor long-term toxicity is to systematically follow the survivors, which is generally not feasible. Instead, cross-sectional surveys are conducted in Hudson et al. (2007 Hudson , M. M. , Rai , S. N. , Nunez , C. , Merchant , T. E. , Marina , N. M. , Zalamea , N. , Cox , C. , Phipps , S. , Pompeu , R. , Rosenthal , D. ( 2007 ). Noninvasive evaluation of late anthracycline cardiac toxicity in childhood cancer survivors . J. Clin. Oncol. 25 : 3635 – 3643 .[Crossref], [PubMed], [Web of Science ®] , [Google Scholar]), with one of the objectives to estimate the cumulative incidence rates along with specific interest in fixed-term (5 or 10 year) rates. We present inference procedures based on current status data to our motivating example with very interesting findings.     

A Bottom-Up Dynamic Model of Portfolio Credit Risk with Stochastic Intensities and Random Recoveries

In Bielecki et al. (2014a Bielecki , T. R. , Cousin , A. , Crépey , S. , Herbertsson , A. ( 2014a ). Dynamic hedging of portfolio credit risk in a markov copula model . J. Optimiz. Theor. Applic . doi: DOI 10.1007/s10957-013-0318-4 (forthcoming) .[Crossref] , [Google Scholar]), the authors introduced a Markov copula model of portfolio credit risk where pricing and hedging can be done in a sound theoretical and practical way. Further theoretical backgrounds and practical details are developed in Bielecki et al. (2014b Bielecki , T. R. , Cousin , A. , Crépey , S. , Herbertsson , A. ( 2014b ). A bottom-up dynamic model of portfolio credit risk - Part I: Markov copula perspective . In: Recent Adv. Fin. Eng. 2012 , World Scientific (preprint version available at http://dx.doi.org/10.2139/ssrn.1844574) . [Google Scholar],c) where numerical illustrations assumed deterministic intensities and constant recoveries. In the present paper, we show how to incorporate stochastic default intensities and random recoveries in the bottom-up modeling framework of Bielecki et al. (2014a Bielecki , T. R. , Cousin , A. , Crépey , S. , Herbertsson , A. ( 2014a ). Dynamic hedging of portfolio credit risk in a markov copula model . J. Optimiz. Theor. Applic . doi: DOI 10.1007/s10957-013-0318-4 (forthcoming) .[Crossref] , [Google Scholar]) while preserving numerical tractability. These two features are of primary importance for applications like CVA computations on credit derivatives (Assefa et al., 2011 Assefa , S. , Bielecki , T. R. , Crépey , S. , Jeanblanc , M. ( 2011 ). CVA computation for counterparty risk assessment in credit portfolios . In: Bielecki , T.R. , Brigo , D. , Patras , F. , Eds., Credit Risk Frontiers . Hoboken : Wiley/Bloomberg-Press . [Google Scholar]; Bielecki et al., 2012 Bielecki , T. R. , Crépey , S. , Jeanblanc , M. , Zargari , B. ( 2012 ). Valuation and Hedging of CDS counterparty exposure in a markov copula model . Int. J. Theoret. Appl. Fin. 15 ( 1 ): 1250004 .[Crossref] , [Google Scholar]), as CVA is sensitive to the stochastic nature of credit spreads and random recoveries allow to achieve satisfactory calibration even for “badly behaved” data sets. This article is thus a complement to Bielecki et al. (2014a Bielecki , T. R. , Cousin , A. , Crépey , S. , Herbertsson , A. ( 2014a ). Dynamic hedging of portfolio credit risk in a markov copula model . J. Optimiz. Theor. Applic . doi: DOI 10.1007/s10957-013-0318-4 (forthcoming) .[Crossref] , [Google Scholar]), Bielecki et al. (2014b Bielecki , T. R. , Cousin , A. , Crépey , S. , Herbertsson , A. ( 2014b ). A bottom-up dynamic model of portfolio credit risk - Part I: Markov copula perspective . In: Recent Adv. Fin. Eng. 2012 , World Scientific (preprint version available at http://dx.doi.org/10.2139/ssrn.1844574) . [Google Scholar]) and Bielecki et al. (2014c Bielecki , T. R. , Cousin , A. , Crépey , S. , Herbertsson , A. ( 2014c ). A bottom-up dynamic model of portfolio credit risk - Part II: Common-shock interpretation, calibration and hedging issues . Recent Adv. Fin. Eng. 2012 , World Scientific (preprint version available at http://dx.doi.org/10.2139/ssrn.2245130) . [Google Scholar]).     

A Note on the Likelihood Ratio Test for Equality of k Normal Populations

The authors derive the analytic expressions for the mean and variance of the log-likelihood ratio for testing equality of k (k ≥ 2) normal populations, and suggest a chi-square approximation and a gamma approximation to the exact null distribution. Numerical comparisons show that the two approximations and the original beta approximation of Neyman and Pearson (1931 Neyman , J. , Pearson , E. S. ( 1931 ). On the problem of k samples . In: Neyman , J. , Pearson , E. S. , eds. Joint Statistical Papers . Cambridge : Cambridge University Press , pp. 116 – 131 . [Google Scholar]) are all accurate, and the gamma approximation is the most accurate.     

Bootstrap approach to test the homogeneity of order restricted mean vectors when the covariance matrices are unknown

Testing homogeneity of multivariate normal mean vectors under an order restriction when the covariance matrices are unknown, arbitrary positive definite and unequal are considered. This problem of testing has been studied to some extent, for example, by Kulatunga and Sasabuchi (1984 Kulatunga, D. D. S., Sasabuchi, S. (1984). A test of homogeneity of mean vectors against multivariate isotonic alternatives. Mem Fac Sci, Kyushu Univ Ser A Mathemat 38:151–161. [Google Scholar]) when the covariance matrices are known and also Sasabuchi et al. (2003 Sasabuchi, S., Tanaka, K., Tsukamodo, T. (2003). Testing homogeneity of multivariate normal mean vectors under an order restriction when the covariance matrices are common but unknown. Annals of Statistics. 31(5):1517–1536.[Web of Science ®] , [Google Scholar]) and Sasabuchi (2007 Sasabuchi, S. (2007). More powerful tests for homogeneity of multivariate normal mean vectors under an order restriction. Sankhya 69(4):700–716. [Google Scholar]) when the covariance matrices are unknown but common. In this paper, a test statistic is proposed and because of the main advantage of the bootstrap test is that it avoids the derivation of the complex null distribution analytically, a bootstrap test statistic is derived and since the proposed test statistic is location invariance the bootstrap p-value defined logical and some steps are presented to estimate it. Our numerical studies via Monte Carlo simulation show that the proposed bootstrap test can correctly control the type I error rates. The power of the test for some of the p-dimensional normal distributions is computed by Monte Carlo simulation. Also, the null distribution of test statistic is estimated using kernel density. Finally, the bootstrap test is illustrated using a real data.     

Size and Power of Recent Tests for Homogeneity in Exponential Mixtures

The article investigates diagnostic procedures for finite mixture models. The problem is to decide whether given data stem from an exponential distribution or a finite mixture of such distributions. Recently, three new test approaches have been proposed, the modified likelihood ratio test (MLRT) by Chen et al. (2001 Chen , H. , Chen , J. , Kalbfleisch , J. D. ( 2001 ). A modified likelihood ratio test for homogeneity in finite mixture models . Journal of the Royal Statistical Society, B 63 : 19 – 29 .[Crossref] , [Google Scholar]), the ADDS test by Mosler and Seidel (2001 Mosler , K. , Seidel , W. ( 2001 ). Testing for homogeneity in an exponential mixture model . Australian and New Zealand Journal of Statistics 43 : 231 – 247 . [Google Scholar]), and the D-test by Charnigo and Sun (2004 Charnigo , R. , Sun , J. ( 2004 ). Testing homogeneity in a mixture distribution via the l ² distance between competing models . Journal of the American Statistical Society 99 : 488 – 498 .[Taylor & Francis Online], [Web of Science ®] , [Google Scholar]). The size and power of these tests are determined by Monte Carlo simulation and their relative merits are evaluated. We conclude that the ADDS test shows always not much less and under some alternatives, in particular lower contaminations, considerably more power than its competitors. Also, new tables for the ADDS test are provided.     

Marginal Correlation from Logit- and Probit-Beta-Normal Models for Hierarchical Binary Data

In hierarchical data settings, be it of a longitudinal, spatial, multi-level, clustered, or otherwise repeated nature, often the association between repeated measurements attracts at least part of the scientific interest. Quantifying the association frequently takes the form of a correlation function, including but not limited to intraclass correlation. Vangeneugden et al. (2010 Vangeneugden, T., Molenberghs, G., Laenen, A., Geys, H., Beunckens, C., Sotto, C. (2010). Marginal correlation in longitudinal binary data based on generalized linear mixed models. Communi. Stati. Theory &; Methods. 39:3542–3557. [Google Scholar]) derived approximate correlation functions for longitudinal sequences of general data type, Gaussian and non-Gaussian, based on generalized linear mixed-effects models. Here, we consider the extended model family proposed by Molenberghs et al. (2010 Molenberghs, G., Verbeke, G., Demétrio, C., Vieira, A. (2010). A family of generalized linear models for repeated measures with normal and conjugate random effects. Stat. Sci. 25:325–347.[Crossref], [Web of Science ®] , [Google Scholar]). This family flexibly accommodates data hierarchies, intra-sequence correlation, and overdispersion. The family allows for closed-form means, variance functions, and correlation function, for a variety of outcome types and link functions. Unfortunately, for binary data with logit link, closed forms cannot be obtained. This is in contrast with the probit link, for which such closed forms can be derived. It is therefore that we concentrate on the probit case. It is of interest, not only in its own right, but also as an instrument to approximate the logit case, thanks to the well-known probit-logit ‘conversion.’ Next to the general situation, some important special cases such as exchangeable clustered outcomes receive attention because they produce insightful expressions. The closed-form expressions are contrasted with the generic approximate expressions of Vangeneugden et al. (2010 Vangeneugden, T., Molenberghs, G., Laenen, A., Geys, H., Beunckens, C., Sotto, C. (2010). Marginal correlation in longitudinal binary data based on generalized linear mixed models. Communi. Stati. Theory &; Methods. 39:3542–3557. [Google Scholar]) and with approximations derived for the so-called logistic-beta-normal combined model. A simulation study explores performance of the method proposed. Data from a schizophrenia trial are analyzed and correlation functions derived.     

Testing for sphericity in a two-way error components panel data model

This article is concerned with sphericity test for the two-way error components panel data model. It is found that the John statistic and the bias-corrected LM statistic recently developed by Baltagi et al. (2011 Baltagi, B. H., Feng, Q., Kao, C. (2011). Testing for sphericity in a fixed effects panel data model. Econometrics Journal 14:25–47.[Crossref], [Web of Science ®] , [Google Scholar])Baltagi et al. (2012 Baltagi, B. H., Feng, Q., Kao, C. (2012). A Lagrange multiplier test for cross-sectional dependence in a fixed effects panel data model. Journal of Econometrics 170:164–177.[Crossref], [Web of Science ®] , [Google Scholar], which are based on the within residuals, are not helpful under the present circumstances even though they are in the one-way fixed effects model. However, we prove that when the within residuals are properly transformed, the resulting residuals can serve to construct useful statistics that are similar to those of Baltagi et al. (2011 Baltagi, B. H., Feng, Q., Kao, C. (2011). Testing for sphericity in a fixed effects panel data model. Econometrics Journal 14:25–47.[Crossref], [Web of Science ®] , [Google Scholar])Baltagi et al. (2012 Baltagi, B. H., Feng, Q., Kao, C. (2012). A Lagrange multiplier test for cross-sectional dependence in a fixed effects panel data model. Journal of Econometrics 170:164–177.[Crossref], [Web of Science ®] , [Google Scholar]). Simulation results show that the newly proposed statistics perform well under the null hypothesis and several typical alternatives.     

Finite-sample distributions of the Wald,likelihood ratio,and Lagrange multiplier test statistics in the classical linear model

In this note, it is shown that the finite-sample distributions of the Wald, likelihood ratio, and Lagrange multiplier statistics in the classical linear regression model are members of the generalized beta model introduced by McDonald and Xu (1995a McDonald, J.B., Xu, Y.J. (1995a). A generalization of the beta distribution with applications. J. Econom. 66:133–152.[Crossref], [Web of Science ®] , [Google Scholar]). This is useful for examining the properties of these test statistics. For example, this characterization makes it easy to find distribution, quantile, and density functions for each test statistic, makes it clear why Wald tests may overreject the null hypothesis using asymptotic critical values, and formalizes the fact that the Lagrange multiplier statistic follows a distribution with bounded support.     

Book Review: New Introduction to Multiple Time Series Analysis

ABSTRACT

This paper proposes a test for the null hypothesis of periodic stationarity against the alternative hypothesis of periodic integration. We derive the limiting distribution of the test statistic and its characteristic function, which are the same as those of the test developed in Kwiatkowski, Phillips, Schmidt and Shin.[15] Kwiatkowski, D., Phillips, P.C. B., Schmidt, P. and Shin, Y. 1992. Testing the Null Hypothesis of Stationarity against the Alternative of a Unit Root.. Journal of Econometrics, 54: 159–178. [Crossref], [Web of Science ®] , [Google Scholar] We find that some parameters, which we must assume under the alternative, have an important effect on the limiting power, so we should choose such parameters carefully. A Monte Carlo simulation reveals that the test has reasonable power but may be affected by the lag truncation parameter that is used for the correction of nuisance parameters.     

Step-Up Procedure for Multiple Comparison with a Control for Multivariate Normal Means

In this study, we consider the multiple comparison with a control for multivariate normal means. Specifically, we construct a step-up procedure by referring to Dunnett and Tamhane (1992 Dunnett , C. W. , Tamhane , A. C. ( 1992 ). A step-up multiple test procedure . Journal of the American Statistical Association 87 : 162 – 170 .[Taylor & Francis Online], [Web of Science ®] , [Google Scholar]). We derive recursive formulae for determining the critical values of the step-up procedure for a specified significance level. Then we formulate the power of the test. Finally, we compare the step-up procedure with the single-step procedure proposed by Nakamura and Imada (2005 Nakamura , T. , Imada , T. ( 2005 ). Multiple comparison procedure of Dunnett's type for multivariate normal means . Journal of the Japanese Society of Computational Statistics 18 : 21 – 32 .[Crossref] , [Google Scholar]) and the step-down procedure proposed by Imada and Douke (2007 Imada , T. , Douke , H. ( 2007 ). Step down procedure for comparing several treatments with a control based on multivariate normal response . Biometrical Journal 49 ( 1 ): 18 – 29 .[Crossref], [Web of Science ®] , [Google Scholar]) in terms of numerical examples regarding the power of the test.     

Measures of predictor sensitivity for order-insensitive partitioning of multiple correlation

Lindeman et al. [12 Lindeman, R. H., Merenda, P. F. and Gold, R. Z. 1980. Introduction to Bivariate and Multivariate Analysis, Glenview, IL: Scott Foresman.  [Google Scholar]] provide a unique solution to the relative importance of correlated predictors in multiple regression by averaging squared semi-partial correlations obtained for each predictor across all p! orderings. In this paper, we propose a series of predictor sensitivity statistics that complement the variance decomposition procedure advanced by Lindeman et al. [12 Lindeman, R. H., Merenda, P. F. and Gold, R. Z. 1980. Introduction to Bivariate and Multivariate Analysis, Glenview, IL: Scott Foresman.  [Google Scholar]]. First, we detail the logic of averaging over orderings as a technique of variance partitioning. Second, we assess predictors by conditional dominance analysis, a qualitative procedure designed to overcome defects in the Lindeman et al. [12 Lindeman, R. H., Merenda, P. F. and Gold, R. Z. 1980. Introduction to Bivariate and Multivariate Analysis, Glenview, IL: Scott Foresman.  [Google Scholar]] variance decomposition solution. Third, we introduce a suite of indices to assess the sensitivity of a predictor to model specification, advancing a series of sensitivity-adjusted contribution statistics that allow for more definite quantification of predictor relevance. Fourth, we describe the analytic efficiency of our proposed technique against the Budescu conditional dominance solution to the uneven contribution of predictors across all p! orderings.