One-sample location tests for multilevel data

In this paper, we consider testing the location parameter with multilevel (or hierarchical) data. A general family of weighted test statistics is introduced. This family includes extensions to the case of multilevel data of familiar procedures like the t, the sign and the Wilcoxon signed-rank tests. Under mild assumptions, the test statistics have a null limiting normal distribution which facilitates their use. An investigation of the relative merits of selected members of the family of tests is achieved theoretically by deriving their asymptotic relative efficiency (ARE) and empirically via a simulation study. It is shown that the performance of a test depends on the clusters configurations and on the intracluster correlations. Explicit formulas for optimal weights and a discussion of the impact of omitting a level are provided for 2 and 3-level data. It is shown that using appropriate weights can greatly improve the performance of the tests. Finally, the use of the new tests is illustrated with a real data example.     

Measurement Errors and Tests for Rationality

The traditional tests for rationality, the regression and volatility tests, have often rejected the hypothesis of rationality for survey data on expectations. It has been argued that these tests are not valid in the presence of unit roots and hence cointegration tests should be applied. The cointegration tests have often failed to reject the hypothesis of rationality. The present article argues that errors in variables affect tests of rationality. We use multiple sources of expectations to correct for the errors-in-variables bias but find that the hypothesis of rationality is rejected even after this correction. The article uses survey data on interest rates, stock prices, and exchange rates.     

Tests for exponentiality

The idea of measuring the departure of data bu a plot of obeserved observations against their expectation has been expeetations has been exploited in this paper to develop tests for exponentiality the tests are for parameter two parameter exponential distribution with complete sample and one parameter exponential distribution with complete sample and one large sample distributions of the test statistics critical points have been computed for different levels of significance and applications of these have been computed for differents levels of significance and applications of these tests have been discussed in case of three data sets.     

Two-sample tests for sparse high-dimensional binary data

In this article, we study the methods for two-sample hypothesis testing of high-dimensional data coming from a multivariate binary distribution. We test the random projection method and apply an Edgeworth expansion for improvement. Additionally, we propose new statistics which are especially useful for sparse data. We compare the performance of these tests in various scenarios through simulations run in a parallel computing environment. Additionally, we apply these tests to the 20 Newsgroup data showing that our proposed tests have considerably higher power than the others for differentiating groups of news articles with different topics.     

Linear Signed-Rank Tests for Paired Survival Data Subject to a Common Censoring Time

In this paper we consider rank-based tests for paired survival data, in which pair members are subject to the same right censoring time. Linear signed-rank tests have already been developed for the two-treatment problem in which pair members receive the opposite treatments. Assuming a bivariate accelerated failure time model, we extend this class of linear signed-rank tests to the case of multiple covariates, making this methodology applicable to more complicated experimental designs. These tests can be reformulated as weighted sums of contigency table measures, giving an alternative method of computation and intuitive view of how these tests work. A simulation study of their small-sample performance relative to other tests demonstrates that the linear signed-rank tests have greater power in cases of moderately to highly correlated data.     

Estimation and goodness-of-fit for the Cox model with various types of censored data

The currently existing estimation methods and goodness-of-fit tests for the Cox model mainly deal with right censored data, but they do not have direct extension to other complicated types of censored data, such as doubly censored data, interval censored data, partly interval-censored data, bivariate right censored data, etc. In this article, we apply the empirical likelihood approach to the Cox model with complete sample, derive the semiparametric maximum likelihood estimators (SPMLE) for the Cox regression parameter and the baseline distribution function, and establish the asymptotic consistency of the SPMLE. Via the functional plug-in method, these results are extended in a unified approach to doubly censored data, partly interval-censored data, and bivariate data under univariate or bivariate right censoring. For these types of censored data mentioned, the estimation procedures developed here naturally lead to Kolmogorov-Smirnov goodness-of-fit tests for the Cox model. Some simulation results are presented.     

A Class of Permutation Tests for the Equality of Two Marginal Survival Functions Using Paired Censored Data

We studied several test statistics for testing the equality of marginal survival functions of paired censored data. The null distribution of the test statistics was approximated by permutation. These tests do not require explicit modeling or estimation of the within-pair correlation, accommodate both paired data and singletons, and the computation is straightforward with most statistical software. Numerical studies showed that these tests have competitive size and power performance. One test statistic has higher power than previously published test statistics when the two survival functions under comparison cross. We illustrate use of these tests in a propensity score matched dataset.     

An alternative method for evaluating stationarity in transition models

Transition models are an important framework that can be used to model longitudinal categorical data. A relevant issue in applying these models is the condition of stationarity, or homogeneity of transition probabilities over time. We propose two tests to assess stationarity in transition models: Wald and likelihood-ratio tests, which do not make use of transition probabilities, using only the estimated parameters of the models in contrast to the classical test available in the literature. In this paper, we present two motivating studies, with ordinal longitudinal data, to which proportional odds transition models are fitted and the two proposed tests are applied as well as the classical test. Additionally, their performances are assessed through simulation studies. The results show that the proposed tests have good performance, being better for control of type-I error and they present equivalent power functions asymptotically. Also, the correlations between the Wald, likelihood-ratio and the classical test statistics are positive and large, an indicator of general concordance. Additionally, both of the proposed tests are more flexible and can be applied in studies with qualitative and quantitative covariates.     

Unmasking the Trend Sought by Jonckheere-Type Tests for Right-Censored Data

Medical and epidemiological studies often involve groups of subjects associated with increasing levels of exposure to a risk factor. Survival of the groups is expected to follow the same order as the level of exposure. Formal tests for this trend fall into the regression framework if one knows what function of exposure to use as a covariate. When unknown, a linear function of exposure level is often used. Jonckheere-type tests for trend have generated continued interest largely because they do not require specification of a covariate. This paper shows that the Jonckheere-type test statistics are special cases of a generalized linear rank statistic with time-dependent covariates which unfortunately depend on the initial group sizes and censoring distributions. Using asymptotic relative efficiency calculations, the Jonckheere tests are compared to standard linear rank tests based on a linear covariate over a spectrum of shapes for the true trend.     

A likelihood-based approach for multivariate one-sided tests with missing data

Inequality-restricted hypotheses testing methods containing multivariate one-sided testing methods are useful in practice, especially in multiple comparison problems. In practice, multivariate and longitudinal data often contain missing values since it may be difficult to observe all values for each variable. However, although missing values are common for multivariate data, statistical methods for multivariate one-sided tests with missing values are quite limited. In this article, motivated by a dataset in a recent collaborative project, we develop two likelihood-based methods for multivariate one-sided tests with missing values, where the missing data patterns can be arbitrary and the missing data mechanisms may be non-ignorable. Although non-ignorable missing data are not testable based on observed data, statistical methods addressing this issue can be used for sensitivity analysis and might lead to more reliable results, since ignoring informative missingness may lead to biased analysis. We analyse the real dataset in details under various possible missing data mechanisms and report interesting findings which are previously unavailable. We also derive some asymptotic results and evaluate our new tests using simulations.     

Nonparametric two-sample tests for dispersion differences based on placements

Two different two-sample tests for dispersion differences based on placement statistics are proposed. The means and variances of the test statistics are derived, and asymptotic normality is established for both. Variants of the proposed tests based on reversing the X and Y labels in the test statistic calculations are shown to have different small-sample properties; for both pairs of tests, one member of the pair will be resolving, the other nonresolving. The proposed tests are similar in spirit to the dispersion tests of both Mood and Hollander; comparative simulation results for these four tests are given. For small sample sizes, the powers of the proposed tests are approximately equal to the powers of the tests of both Mood and Hollander for samples from the normal, Cauchy and exponential distributions. The one-sample limiting distributions are also provided, yielding useful approximations to the exact tests when one sample is much larger than the other. A bootstrap test may alternatively be performed. The proposed test statistics may be used with lightly censored data by substituting Kaplan-Meier estimates for the empirical distribution functions.     

A Test for Slope Heterogeneity in Fixed Effects Models

Typical panel data models make use of the assumption that the regression parameters are the same for each individual cross-sectional unit. We propose tests for slope heterogeneity in panel data models. Our tests are based on the conditional Gaussian likelihood function in order to avoid the incidental parameters problem induced by the inclusion of individual fixed effects for each cross-sectional unit. We derive the Conditional Lagrange Multiplier test that is valid in cases where N → ∞ and T is fixed. The test applies to both balanced and unbalanced panels. We expand the test to account for general heteroskedasticity where each cross-sectional unit has its own form of heteroskedasticity. The modification is possible if T is large enough to estimate regression coefficients for each cross-sectional unit by using the MINQUE unbiased estimator for regression variances under heteroskedasticity. All versions of the test have a standard Normal distribution under general assumptions on the error distribution as N → ∞. A Monte Carlo experiment shows that the test has very good size properties under all specifications considered, including heteroskedastic errors. In addition, power of our test is very good relative to existing tests, particularly when T is not large.     

Testing for overdispersion in a censored Poisson regression model

In this article, we investigate the efficiency of score tests for testing a censored Poisson regression model against censored negative binomial regression alternatives. Based on the results of a simulation study, score tests using the normal approximation, underestimate the nominal significance level. To remedy this problem, bootstrap methods are proposed. We find that bootstrap methods keep the significance level close to the nominal one and have greater power uniformly than does the normal approximation for testing the hypothesis.     

A class of simple approximate sequential tests for adaptive comparison of two treatments

We consider the problem of sequentially deciding which of two treatments is superior, A class of simple approximate sequential tests is proposed. These have the probabilities of correct selection approximately independent of the sampling rule and depending on unknown parameters only through the function of interest, such as the difference or ratio of mean responses. The tests are obtained by using a normal approximation, and this is employed to derive approximate expressions for the probabilities of correct selection and the expected sample sizes. A class of data-dependent sampling rules is proposed for minimizing any weighted average of the expected sample sizes on the two treatments, with the weights being allowed to depend on unknown parameters. The tests are studied in the particular cases of exponentially.     

Non parametric Bayesian analysis of the two-sample problem with censoring

Testing for differences between two groups is a fundamental problem in statistics, and due to developments in Bayesian non parametrics and semiparametrics there has been renewed interest in approaches to this problem. Here we describe a new approach to developing such tests and introduce a class of such tests that take advantage of developments in Bayesian non parametric computing. This class of tests uses the connection between the Dirichlet process (DP) prior and the Wilcoxon rank sum test but extends this idea to the DP mixture prior. Here tests are developed that have appropriate frequentist sampling procedures for large samples but have the potential to outperform the usual frequentist tests. Extensions to interval and right censoring are considered and an application to a high-dimensional data set obtained from an RNA-Seq investigation demonstrates the practical utility of the method.     

An R package for testing goodness of fit: goft

This R package implements three types of goodness-of-fit tests for some widely used probability distributions where there are unknown parameters, namely tests based on data transformations, on the ratio of two estimators of a dispersion parameter, and correlation tests. Most of the considered tests have been proved to be powerful against a wide range of alternatives and some new ones are proposed here. The package's functionality is illustrated with several examples by using some data sets from the areas of environmental studies, biology and finance, among others.     

Testing for State Dependence with Time-Variant Transition Probabilities

We derive a simple result that allows us to test for the presence of state dependence in a dynamic Logit model with time-variant transition probabilities and an arbitrary distribution of the unobserved heterogeneity. Monte Carlo evidence suggests that this test has desirable properties even when there are some violations of the model's assumptions. We also consider alternative tests that will have desirable properties only when the transition probabilities do not depend on time and provide evidence that there is an “acceptable” range in which ignoring time-dependence does not matter too much. We conclude with an application to the Barker Hypothesis.     

Testing for State Dependence with Time-Variant Transition Probabilities

We derive a simple result that allows us to test for the presence of state dependence in a dynamic Logit model with time-variant transition probabilities and an arbitrary distribution of the unobserved heterogeneity. Monte Carlo evidence suggests that this test has desirable properties even when there are some violations of the model's assumptions. We also consider alternative tests that will have desirable properties only when the transition probabilities do not depend on time and provide evidence that there is an “acceptable” range in which ignoring time-dependence does not matter too much. We conclude with an application to the Barker Hypothesis.     

Likelihood ratio type unit root tests for ar(1)models with nonconsecutive observations

For the nonconsecutively observed or missing data situation likelihood ratio type unit root tests in AR(1)models containing an intercept or both an intercept and a time trend are proposed and are shown to have the same limiting distributions as the likelihood ratio tests for the complete data case as tabulated by Dickey and Fuller(1981). Some simulation results on our tests in finite samples under A–B sampling schemes are also presented.     

Testing for Panel Unit Roots under General Cross-sectional Dependence

In this article, we generalize four tests of multivariate linear hypothesis to panel data unit root testing. The test statistics are invariant to certain linear transformations of data and therefore simulated critical values may conveniently be used. It is demonstrated that all four tests remains well behaved in cases of where there are heterogeneous alternatives and cross-correlations between marginal variables. A Monte Carlo simulation is included to compare and contrast the tests with two well-established ones.