Variational Bayes for estimating the parameters of a hidden Potts model

Hidden Markov random field models provide an appealing representation of images and other spatial problems. The drawback is that inference is not straightforward for these models as the normalisation constant for the likelihood is generally intractable except for very small observation sets. Variational methods are an emerging tool for Bayesian inference and they have already been successfully applied in other contexts. Focusing on the particular case of a hidden Potts model with Gaussian noise, we show how variational Bayesian methods can be applied to hidden Markov random field inference. To tackle the obstacle of the intractable normalising constant for the likelihood, we explore alternative estimation approaches for incorporation into the variational Bayes algorithm. We consider a pseudo-likelihood approach as well as the more recent reduced dependence approximation of the normalisation constant. To illustrate the effectiveness of these approaches we present empirical results from the analysis of simulated datasets. We also analyse a real dataset and compare results with those of previous analyses as well as those obtained from the recently developed auxiliary variable MCMC method and the recursive MCMC method. Our results show that the variational Bayesian analyses can be carried out much faster than the MCMC analyses and produce good estimates of model parameters. We also found that the reduced dependence approximation of the normalisation constant outperformed the pseudo-likelihood approximation in our analysis of real and synthetic datasets.     

Alternative Bayes factors for model selection

Several alternative Bayes factors have been recently proposed in order to solve the problem of the extreme sensitivity of the Bayes factor to the priors of models under comparison. Specifically, the impossibility of using the Bayes factor with standard noninformative priors for model comparison has led to the introduction of new automatic criteria, such as the posterior Bayes factor (Aitkin 1991), the intrinsic Bayes factors (Berger and Pericchi 1996b) and the fractional Bayes factor (O'Hagan 1995). We derive some interesting properties of the fractional Bayes factor that provide justifications for its use additional to the ones given by O'Hagan. We further argue that the use of the fractional Bayes factor, originally introduced to cope with improper priors, is also useful in a robust analysis. Finally, using usual classes of priors, we compare several alternative Bayes factors for the problem of testing the point null hypothesis in the univariate normal model.     

Bayes and Empirical Bayes Estimation of the Parameter n in a Binomial Distribution

The problem of estimating the total number of trials n in a binomial distribution is reconsidered in this article for both cases of known and unknown probability of success p from the Bayesian viewpoint. Bayes and empirical Bayes point estimates for n are proposed under the assumption of a left-truncated prior distribution for n and a beta prior distribution for p. Simulation studies are provided in this article in order to compare the proposed estimate with the most familiar n estimates.     

On Variational Bayes Estimation and Variational Information Criteria for Linear Regression Models

Variational Bayes (VB) estimation is a fast alternative to Markov Chain Monte Carlo for performing approximate Baesian inference. This procedure can be an efficient and effective means of analyzing large datasets. However, VB estimation is often criticised, typically on empirical grounds, for being unable to produce valid statistical inferences. In this article we refute this criticism for one of the simplest models where Bayesian inference is not analytically tractable, that is, the Bayesian linear model (for a particular choice of priors). We prove that under mild regularity conditions, VB based estimators enjoy some desirable frequentist properties such as consistency and can be used to obtain asymptotically valid standard errors. In addition to these results we introduce two VB information criteria: the variational Akaike information criterion and the variational Bayesian information criterion. We show that variational Akaike information criterion is asymptotically equivalent to the frequentist Akaike information criterion and that the variational Bayesian information criterion is first order equivalent to the Bayesian information criterion in linear regression. These results motivate the potential use of the variational information criteria for more complex models. We support our theoretical results with numerical examples.     

Bayes and Empirical Bayes Inference in Changepoint Problems

ABSTRACT

In the case of the random design nonparametric regression, the double smoothing technique is applied to estimate the multivariate regression function. The proposed estimator has desirable properties in both the finite sample and the asymptotic cases. In the finite sample case, it has bounded conditional (and unconditional) bias and variance. On the other hand, in the asymptotic case, it has the same mean square error as the local linear estimator in Fan (Design-Adaptive Nonparametric Regression. Journal of the American Statistical Association 1992, 87, 998–1004; Local Linear Regression Smoothers and Their Minimax Efficiencies. Annals of Statistics 1993, 21, 196–216). Simulation studies demonstrate that the proposed estimator is better than the local linear estimator, because it has a smaller sample mean integrated square error and gives smoother estimates.     

Adaptive power priors with empirical Bayes for clinical trials

Incorporating historical information into the design and analysis of a new clinical trial has been the subject of much discussion as a way to increase the feasibility of trials in situations where patients are difficult to recruit. The best method to include this data is not yet clear, especially in the case when few historical studies are available. This paper looks at the power prior technique afresh in a binomial setting and examines some previously unexamined properties, such as Box P values, bias, and coverage. Additionally, it proposes an empirical Bayes‐type approach to estimating the prior weight parameter by marginal likelihood. This estimate has advantages over previously criticised methods in that it varies commensurably with differences in the historical and current data and can choose weights near 1 when the data are similar enough. Fully Bayesian approaches are also considered. An analysis of the operating characteristics shows that the adaptive methods work well and that the various approaches have different strengths and weaknesses.     

Objective Bayes Factors for Gaussian Directed Acyclic Graphical Models

Abstract. We propose an objective Bayesian method for the comparison of all Gaussian directed acyclic graphical models defined on a given set of variables. The method, which is based on the notion of fractional Bayes factor (BF), requires a single default (typically improper) prior on the space of unconstrained covariance matrices, together with a prior sample size hyper‐parameter, which can be set to its minimal value. We show that our approach produces genuine BFs. The implied prior on the concentration matrix of any complete graph is a data‐dependent Wishart distribution, and this in turn guarantees that Markov equivalent graphs are scored with the same marginal likelihood. We specialize our results to the smaller class of Gaussian decomposable undirected graphical models and show that in this case they coincide with those recently obtained using limiting versions of hyper‐inverse Wishart distributions as priors on the graph‐constrained covariance matrices.     

Variational Inference for Heteroscedastic Semiparametric Regression

We develop fast mean field variational methodology for Bayesian heteroscedastic semiparametric regression, in which both the mean and variance are smooth, but otherwise arbitrary, functions of the predictors. Our resulting algorithms are purely algebraic, devoid of numerical integration and Monte Carlo sampling. The locality property of mean field variational Bayes implies that the methodology also applies to larger models possessing variance function components. Simulation studies indicate good to excellent accuracy, and considerable time savings compared with Markov chain Monte Carlo. We also provide some illustrations from applications.     

Bayes least squares linear estimation of densities

Linear, least squares statistical methods in which the "parameters" are interpreted as random variables were introduced by Whittle, and further developed by Hartigan and others. They are applied here to the problem of estimating the coefficients in an orthogonal expansion of a multivariate density, given a simple random sample.     

Constrained Bayes and Empirical Bayes Estimation with Balanced Loss Functions

This article develops constrained Bayes and empirical Bayes estimators under balanced loss functions. In the normal-normal example, estimators of the mean squared errors of the EB and constrained EB estimators are provided which are correct asymptotically up to O(m ^?1), m denoting the number of strata.     

基于贝叶斯方法的信用风险损失分布研究

现代商业银行进行经济资本配置时,采用的损失分布函数都存在严重的失真问题。运用贝叶斯方法,充分利用各种信息对正态分布形式的信用损失分布进行了修正,得到信用风险损失分布的优化模型,结果表明：修正后的信用风险损失分布具有较高的精度,从而为商业银行经济资本管理提供了一种很实用的管理工具。     

指数族分布中参数的经验贝叶斯估计

指数族分布是一类应用广泛的分布类,包括了泊松分布、Gamma分布、Beta分布、二项分布等常见分布.在非寿险中,索赔额或索赔次数过程常常被假定服从指数族分布,由于风险的非齐次性,指数族分布中的参数θ也为随机变量,假定服从指数族共轭先验分布.此时风险参数的估计落入了Bayes框架,风险参数θ的Bayes估计被表达“信度”形式.然而,在实际运用中,由于先验分布与样本分布中仍然含有结构参数,根据样本的边际分布的似然函数估计结构参数,从而获得风险参数的经验Bayes估计,最后证明了该经验Bayes估计是渐近最优的.     

A Comparison of Bayes Factors for Separated Models: Some Simulation Results

Some alternative Bayes Factors: Intrinsic, Posterior, and Fractional have been proposed to overcome the difficulties presented when prior information is weak and improper prior are used. Additional difficulties also appear when the models are separated or non nested. This article presents both simulation results and some illustrative examples analysis comparing these alternative Bayes factors to discriminate among the Lognormal, the Weibull, the Gamma, and the Exponential distributions. Simulation results are obtained for different sample sizes generated from the distributions. Results from simulations indicates that these alternative Bayes factors are useful for comparing non nested models. The simulations also show some similar behavior and that when both models are true they choose the simplest model. Some illustrative example are also presented.     

Bayes two-decision procedures for two-sample problems and rank-order data

A two-sample problem for rank-order data is formulated as a two-decision problem. Using the general Bayes solution, Bayes procedures are derived for several configurations of the set of states of nature including some for which the problem is distribution-free. It is shown that for certain prior distributions these procedures reduce to classical LMP rank tests. Some devices for selection of prior distributions are suggested. It is shown that the Bayes risk of these procedures tends to zero as sample sizes increase.     

A Generalized Bayes Rule for Prediction

In the case of prior knowledge about the unknown parameter, the Bayesian predictive density coincides with the Bayes estimator for the true density in the sense of the Kullback-Leibler divergence, but this is no longer true if we consider another loss function. In this paper we present a generalized Bayes rule to obtain Bayes density estimators with respect to any α-divergence, including the Kullback-Leibler divergence and the Hellinger distance. For curved exponential models, we study the asymptotic behaviour of these predictive densities. We show that, whatever prior we use, the generalized Bayes rule improves (in a non-Bayesian sense) the estimative density corresponding to a bias modification of the maximum likelihood estimator. It gives rise to a correspondence between choosing a prior density for the generalized Bayes rule and fixing a bias for the maximum likelihood estimator in the classical setting. A criterion for comparing and selecting prior densities is also given.     

Bayes and Empirical Bayes Two-Stage Procedures for Sampling Inspection

A batch of M items is inspected for defectives. Suppose there are d defective items in the batch. Let d ₀ be a given standard used to evaluate the quality of the population where 0 < d ₀ < M. The problem of testing H ₀: d < d ₀ versus H ₁: d ≥ d ₀ is considered. It is assumed that past observations are available when the current testing problem is considered. Accordingly, the empirical Bayes approach is employed. By using information obtained from the past data, an empirical Bayes two-stage testing procedure is developed. The associated asymptotic optimality is investigated. It is proved that the rate of convergence of the empirical Bayes two-stage testing procedure is of order O (exp(? c? n)), for some constant c? > 0, where n is the number of past observations at hand.     

Bayesian inference method for model validation and confidence extrapolation

This paper presents a Bayesian-hypothesis-testing-based methodology for model validation and confidence extrapolation under uncertainty, using limited test data. An explicit expression of the Bayes factor is derived for the interval hypothesis testing. The interval method is compared with the Bayesian point null hypothesis testing approach. The Bayesian network with Markov Chain Monte Carlo simulation and Gibbs sampling is explored for extrapolating the inference from the validated domain at the component level to the untested domain at the system level. The effect of the number of experiments on the confidence in the model validation decision is investigated. The probabilities of Type I and Type II errors in decision-making during the model validation and confidence extrapolation are quantified. The proposed methodologies are applied to a structural mechanics problem. Numerical results demonstrate that the Bayesian methodology provides a quantitative approach to facilitate rational decisions in model validation and confidence extrapolation under uncertainty.     

Posterior Bayes factor analysis for an exponential regression model

In the exponential regression model, Bayesian inference concerning the non-linear regression parameter has proved extremely difficult. In particular, standard improper diffuse priors for the usual parameters lead to an improper posterior for the non-linear regression parameter. In a recent paper Ye and Berger (1991) applied the reference prior approach of Bernardo (1979) and Berger and Bernardo (1989) yielding a proper informative prior for . This prior depends on the values of the explanatory variable, goes to 0 as goes to 1, and depends on the specification of a hierarchical ordering of importance of the parameters.This paper explains the failure of the uniform prior to give a proper posterior: the reason is the appearance of the determinant of the information matrix in the posterior density for . We apply the posterior Bayes factor approach of Aitkin (1991) to this problem; in this approach we integrate out nuisance parameters with respect to their conditional posterior density given the parameter of interest. The resulting integrated likelihood for requires only the standard diffuse prior for all the parameters, and is unaffected by orderings of importance of the parameters. Computation of the likelihood for is extremely simple. The approach is applied to the three examples discussed by Berger and Ye and the likelihoods compared with their posterior densities.     

Empirical Bayes testing for equivalence

For a fixed point θ₀ and a positive value c₀, this paper studies the problem of testing the hypotheses H₀:|θ−θ₀|≤c₀ against H₁:|θ−θ₀|>c₀ for the normal mean parameter θ using the empirical Bayes approach. With the accumulated past data, a monotone empirical Bayes test is constructed by mimicking the behavior of a monotone Bayes test. Such an empirical Bayes test is shown to be asymptotically optimal and its regret converges to zero at a rate (lnn)^2.5/n where n is the number of past data available, when the current testing problem is considered. A simulation study is also given, and the results show that the proposed empirical Bayes procedure has good performance for small to moderately large sample sizes. Our proposed method can be applied for testing close to a control problem or testing the therapeutic equivalence of one standard treatment compared to another in clinical trials.