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1.
Blaisdell and Raghavarao (1980 1985) introduced partially balanced residual treatment effects designs and gave methods of construction of these designs. They also gave efficiencies for the estimated direct and residual elementary treatment contrasts of these designs. In this paper, we construct some new series of partially balanced residual treatment effects designs and also give their efficiencies for the estimated direct and residual elementary treatment contrasts. 相似文献
2.
Jie Yang 《统计学通讯:模拟与计算》2015,44(9):2264-2277
Generalized linear models (GLMs) have been used widely for modeling the mean response both for discrete and continuous random variables with an emphasis on categorical response. Recently Yang, Mandal and Majumdar (2013) considered full factorial and fractional factorial locally D-optimal designs for binary response and two-level experimental factors. In this article, we extend their results to a general setup with response belonging to a single-parameter exponential family and for multilevel predictors. 相似文献
3.
In this article, we consider two different shared frailty regression models under the assumption of Gompertz as baseline distribution. Mostly assumption of gamma distribution is considered for frailty distribution. To compare the results with gamma frailty model, we consider the inverse Gaussian shared frailty model also. We compare these two models to a real life bivariate survival data set of acute leukemia remission times (Freireich et al., 1963). Analysis is performed using Markov Chain Monte Carlo methods. Model comparison is made using Bayesian model selection criterion and a well-fitted model is suggested for the acute leukemia data. 相似文献
4.
Sharma (1977) and Aggarwal et al. (2006) considered non circular construction of first- and second-order balanced repeated measurements designs. Sharma et al. (2002) constructed circular first- and second-order balanced repeated measurements designs only for a class with parameters (v, p = 3n, n = v 2) and also showed its universal optimality. In this article, we consider circular construction of first- and second-order balanced repeated measurements designs and strongly balanced repeated measurements designs by using the method of cyclic shifts. Some new circular designs with parameters (v, p, n) for cases p = v, p < v and p > v are given. 相似文献
5.
In this article, the exchange and interchange algorithm of Zergaw (1989) and Martin and Eccleston (1992) have been modified and used for searching efficient block designs for making all possible pairwise treatment comparisons when observations are dependent. The lower bounds to the A- and D-efficiencies of the designs in a given class of the designs have been obtained for correlated observation structure and the procedure of computing lower bounds to A- and D-efficiencies has been incorporated in the algorithm. The algorithm has been translated into a computer program using Microsoft Visual C++. Using this program, a search for efficient designs for making all possible pairwise treatment comparisons has been made for v ≤ 10, b ≤ 33, k ≤ 10 such that bk ≤ 100 and v > k. The block designs considered are usual block designs (rectangular block designs) and circular block designs. Nearest neighbor (NN), autoregressive of order 1 (AR(1)) correlation structures are studied. The ranges of correlation coefficients for different correlation structures investigated are |ρ|≤0.50 for NN correlation structure in rectangular blocks, |ρ|≤0.45 for NN correlation structure in circular blocks, and |ρ|≤0.95 for AR(1) correlation structure. For these ranges, the matrix of correlation coefficients among observations within a block is positive definite. Robustness aspects of designs that are efficient for a given value of correlation have been investigated against other values of correlation coefficients. Robustness aspects of designs that are efficient for independent observations have also been studied for experimental situations with dependent observations. 相似文献
6.
Junyong Park Jayson D. Wilbur Jayanta K. Ghosh Cindy H. Nakatsu Corinne Ackerman 《统计学通讯:模拟与计算》2013,42(4):855-869
We adopt boosting for classification and selection of high-dimensional binary variables for which classical methods based on normality and non singular sample dispersion are inapplicable. Boosting seems particularly well suited for binary variables. We present three methods of which two combine boosting with the relatively classical variable selection methods developed in Wilbur et al. (2002). Our primary interest is variable selection in classification with small misclassification error being used as validation of proposed method for variable selection. Two of the new methods perform uniformly better than Wilbur et al. (2002) in one set of simulated and three real life examples. 相似文献
7.
《统计学通讯:理论与方法》2012,41(13-14):2445-2455
In this article, the problem of estimation of the individual weights of three objects using a chemical balance weighing design is considered. We use the criterion of D-optimality. We assume that the covariance matrix of errors is the matrix of first-order autoregressive process. Such problems were discussed in Li and Yang (2005) and also in Yeh and Lo Huang (2005). We present some results of D-optimal designs in certain class of designs with the design matrix X ∈ M n×3(±1) such that each column of matrix X has at least one 1 and one ?1. 相似文献
8.
This article extends the correlation methodology developed by Chinchilli et al. (2005) for the 2 × 2 crossover design to more complex crossover designs for clinical trials. We describe how the methodology can be adapted to a general type of two-treatment crossover design which includes either at least two sequences or at least two treatment periods or both. We then derive the asymptotic theory for the corresponding correlation statistics, investigate the statistical accuracy of the estimators via bootstrap analyses, and demonstrate their use with two real data examples. 相似文献
9.
Viswanathan Ramakrishnan 《统计学通讯:模拟与计算》2013,42(3):405-418
In many genetic analyses of dichotomous twin data, odds ratios have been used to test hypotheses on heritability and shared common environment effects of a given disease (Lichtenstein et al., 2000; Ahlbom et al., 1997; Ramakrishnan et al., 1992, 4). However, estimates of these two effects have not been dealt with in the literature. In epidemiology, the attributable fraction (AF), a function of the odds ratio and the prevalence of the risk factor has been used to describe the contribution of a risk factor to a disease in a given population (Leviton, 1973). In this article, we adapt the AF to quantify the heritability and the shared common environment. Twin data on cancer, gallstone disease and phobia are used to illustrate the applicability of the AF estimate as a measure of heritability. 相似文献
10.
The objective of this paper is to study U-type designs for Bayesian non parametric response surface prediction under correlated errors. The asymptotic Bayes criterion is developed in terms of the asymptotic approach of Mitchell et al. (1994) for a more general covariance kernel proposed by Chatterjee and Qin (2011). A relationship between the asymptotic Bayes criterion and other criteria, such as orthogonality and aberration, is then developed. A lower bound for the criterion is also obtained, and numerical results show that this lower bound is tight. The established results generalize those of Yue et al. (2011) from symmetrical case to asymmetrical U-type designs. 相似文献
11.
This article suggests random and fixed effects spatial two-stage least squares estimators for the generalized mixed regressive spatial autoregressive panel data model. This extends the generalized spatial panel model of Baltagi et al. (2013) by the inclusion of a spatial lag term. The estimation method utilizes the Generalized Moments method suggested by Kapoor et al. (2007) for a spatial autoregressive panel data model. We derive the asymptotic distributions of these estimators and suggest a Hausman test a la Mutl and Pfaffermayr (2011) based on the difference between these estimators. Monte Carlo experiments are performed to investigate the performance of these estimators as well as the corresponding Hausman test. 相似文献
12.
Tony Vangeneugden Geert Verbeke Clarice G.B. Demétrio 《Journal of applied statistics》2011,38(2):215-232
Vangeneugden et al. [15] derived approximate correlation functions for longitudinal sequences of general data type, Gaussian and non-Gaussian, based on generalized linear mixed-effects models (GLMM). Their focus was on binary sequences, as well as on a combination of binary and Gaussian sequences. Here, we focus on the specific case of repeated count data, important in two respects. First, we employ the model proposed by Molenberghs et al. [13], which generalizes at the same time the Poisson-normal GLMM and the conventional overdispersion models, in particular the negative-binomial model. The model flexibly accommodates data hierarchies, intra-sequence correlation, and overdispersion. Second, means, variances, and joint probabilities can be expressed in closed form, allowing for exact intra-sequence correlation expressions. Next to the general situation, some important special cases such as exchangeable clustered outcomes are considered, producing insightful expressions. The closed-form expressions are contrasted with the generic approximate expressions of Vangeneugden et al. [15]. Data from an epileptic-seizures trial are analyzed and correlation functions derived. It is shown that the proposed extension strongly outperforms the classical GLMM. 相似文献
13.
Tony Vangeneugden Geert Molenberghs Geert Verbeke Clarice G.B. Demétrio 《统计学通讯:理论与方法》2014,43(19):4164-4178
In hierarchical data settings, be it of a longitudinal, spatial, multi-level, clustered, or otherwise repeated nature, often the association between repeated measurements attracts at least part of the scientific interest. Quantifying the association frequently takes the form of a correlation function, including but not limited to intraclass correlation. Vangeneugden et al. (2010) derived approximate correlation functions for longitudinal sequences of general data type, Gaussian and non-Gaussian, based on generalized linear mixed-effects models. Here, we consider the extended model family proposed by Molenberghs et al. (2010). This family flexibly accommodates data hierarchies, intra-sequence correlation, and overdispersion. The family allows for closed-form means, variance functions, and correlation function, for a variety of outcome types and link functions. Unfortunately, for binary data with logit link, closed forms cannot be obtained. This is in contrast with the probit link, for which such closed forms can be derived. It is therefore that we concentrate on the probit case. It is of interest, not only in its own right, but also as an instrument to approximate the logit case, thanks to the well-known probit-logit ‘conversion.’ Next to the general situation, some important special cases such as exchangeable clustered outcomes receive attention because they produce insightful expressions. The closed-form expressions are contrasted with the generic approximate expressions of Vangeneugden et al. (2010) and with approximations derived for the so-called logistic-beta-normal combined model. A simulation study explores performance of the method proposed. Data from a schizophrenia trial are analyzed and correlation functions derived. 相似文献
14.
Suppose that some information is available for the particular factor. The experimenter may apply the technique of foldover to isolate the factor and the two-factor interactions involving this factor. In fact, under some situations this can be done by the method of semi-folding. We will discuss this property in detail in this article. Furthermore, we use the computer to search the corresponding optimal semi-folding design for the given 2 k?p designs that are tabulated in Chen et al. (1993) research. 相似文献
15.
《统计学通讯:理论与方法》2013,42(7):1579-1586
ABSTRACT Recently, Ghosh and Das (2003) considered the estimation of variance components and the variances of these estimates. While comparing the yielding capacities of the cross (i, j), Kempthorne and Curnow (1961) proposed the estimation of the yielding capacity of any cross based on the least square estimators of the general combining ability effects and/or the mean yield of the cross (i, j). In this article, the problem of predicting the yielding capacity of the cross (i, j) from the sample of inbred lines has been considered. The properties of the best linear unbiased predictor for predicting the unobserved general combining ability effects together with general mean effect has been studied. We characterize A-optimal complete diallel cross designs and some efficient partial diallel cross designs under this setup. 相似文献
16.
The authors derive the analytic expressions for the mean and variance of the log-likelihood ratio for testing equality of k (k ≥ 2) normal populations, and suggest a chi-square approximation and a gamma approximation to the exact null distribution. Numerical comparisons show that the two approximations and the original beta approximation of Neyman and Pearson (1931) are all accurate, and the gamma approximation is the most accurate. 相似文献
17.
Cai et al. (2008) explored the optimal reinsurance designs among the class of increasing convex reinsurance treaties under VaR and CTE risk measures. However, reinsurance contracts always involve a limit on the ceded loss function in practice, and thus it may not be enough to confine the analysis to the class of convex functions only. The object of this article is to present an optimal reinsurance policy under VaR and CTE optimization criteria when the ceded loss function is in a class of increasing concave functions and the reinsurance premium is determined by the expected value principle. The outcomes reveal that the optimal form and amount of reinsurance depend on the confidence level p for the risk measure and the safety loading θ for the reinsurance premium. It is shown that under the VaR optimization criterion, the quota-share reinsurance with a policy limit is optima, while the full reinsurance with a policy limit is optima under CTE optimization criterion. Some illustrative examples are provided. 相似文献
18.
《统计学通讯:理论与方法》2013,42(5):875-885
The order of experimental runs in a fractional factorial experiment is essential when the cost of level changes in factors is considered. The generalized foldover scheme given by [1]gives an optimal order to experimental runs in an experiment with specified defining contrasts. An experiment can be specified by a design requirement such as resolution or estimation of some interactions. To meet such a requirement, we can find several sets of defining contrasts. Applying the generalized foldover scheme to these sets of defining contrasts, we obtain designs with different numbers of level changes and then the design with minimum number of level changes. The difficulty is to find all the sets of defining contrasts. An alternative approach is investigated by [2]for two-level fractional factorial experiments. In this paper, we investigate experiments with all factors in slevels. 相似文献
19.
The Significance Analysis of Microarrays (SAM; Tusher et al., 2001) method is widely used in analyzing gene expression data while controlling the FDR by using resampling-based procedure in the microarray setting. One of the main components of the SAM procedure is the adjustment of the test statistic. The introduction of the fudge factor to the test statistic aims at deflating the large value of test statistics due to the small standard error of gene-expression. Lin et al. (2008) pointed out that the fudge factor does not effectively improve the power and the control of the FDR as compared to the SAM procedure without the fudge factor in the presence of small variance genes. Motivated by the simulation results presented in Lin et al. (2008), in this article, we extend our study to compare several methods for choosing the fudge factor in the modified t-type test statistics and use simulation studies to investigate the power and the control of the FDR of the considered methods. 相似文献
20.
Antonello D'Ambra 《统计学通讯:理论与方法》2014,43(6):1209-1221
Non Symmetric Correspondence Analysis (NSCA) (D'Ambra and Lauro, 1989) is a useful technique for analyzing a two-way contingency table. The key difference between the symmetrical and non symmetrical versions of correspondence analysis rests on the measure of the association used to quantify the relationship between the variables. For a two-way, or multi-way, contingency table, the Pearson chi-squared statistic is commonly used when it can be assumed that the categorical variables are symmetrically related. However, for a two-way table, it may be that one variable can be treated as a predictor variable and the second variable can be considered as a response variable. Yet, for such a variable structure, the Pearson chi-squared statistic is not an appropriate measure of the association. Instead, one may consider the Goodman-Kruskal tau index. In the case that there are more than two cross-classified variables, multivariate versions of the Goodman-Kruskal tau index can be considered. These include Marcotorchino's index (Marcotorchino, 1985) and Gray-Williams’ index (Gray and Williams, 1975). In this article, the Multiple non Symmetric Correspondence Analysis (MNSCA), along with the decomposition of the TAU by Gray-Williams in main effects and interaction (D'Ambra et al., 2011), is used for the evaluation of the innovative performance of the manufacturing enterprises in Campania. Finally, to identify a category which is statistically significant, the confidence ellipses have been proposed for the Multiple Non Symmetric Correspondence Analysis starting from the ellipses suggested by Beh (2010) for the symmetrical analysis. 相似文献