A new class of survival regression models with heavy-tailed errors: robustness and diagnostics

Birnbaum-Saunders models have largely been applied in material fatigue studies and reliability analyses to relate the total time until failure with some type of cumulative damage. In many problems related to the medical field, such as chronic cardiac diseases and different types of cancer, a cumulative damage caused by several risk factors might cause some degradation that leads to a fatigue process. In these cases, BS models can be suitable for describing the propagation lifetime. However, since the cumulative damage is assumed to be normally distributed in the BS distribution, the parameter estimates from this model can be sensitive to outlying observations. In order to attenuate this influence, we present in this paper BS models, in which a Student-t distribution is assumed to explain the cumulative damage. In particular, we show that the maximum likelihood estimates of the Student-t log-BS models attribute smaller weights to outlying observations, which produce robust parameter estimates. Also, some inferential results are presented. In addition, based on local influence and deviance component and martingale-type residuals, a diagnostics analysis is derived. Finally, a motivating example from the medical field is analyzed using log-BS regression models. Since the parameter estimates appear to be very sensitive to outlying and influential observations, the Student-t log-BS regression model should attenuate such influences. The model checking methodologies developed in this paper are used to compare the fitted models.     

General standby allocation in series and parallel systems

Stochastic orders are very useful tools to compare the lifetimes of two systems. Optimum lifetime of a series (resp. parallel) system with general standby component(s) depends on the allocation strategy of standby component(s) into the system. Here, we discuss three different models of one or more standby components. In each model, we compare different series (resp. parallel) systems (which are formed through different allocation strategies of standby component(s)) with respect to the usual stochastic order and the stochastic precedence order. The results related to the cold as well as the hot standby models are obtained as particular cases of the results discussed in this article because the model considered here is a general one.     

Generalized Inverse Gamma Distribution and its Application in Reliability

In this article, we introduce a new reliability model of inverse gamma distribution referred to as the generalized inverse gamma distribution (GIG). A generalization of inverse gamma distribution is defined based on the exact form of generalized gamma function of Kobayashi (1991). This function is useful in many problems of diffraction theory and corrosion problems in new machines. The new distribution has a number of lifetime special sub-models. For this model, some of its statistical properties are studied. The method of maximum likelihood is used for estimating the model parameters and the observed information matrix is derived. We also demonstrate the usefulness of this distribution on a real data set.     

Exact Tests in Panel Data Using Generalized p-Values

In this article, we consider exact tests in panel data regression model with one-way and two-way error component for which no exact tests are available. Exact inferences using generalized p-values are obtained. When there are several groups of panel data, test for equal coefficients under one-way and two-way error component are derived.     

Generalized Inference for a Class of Linear Models Under Heteroscedasticity

In this article we study inferences for a class of linear models under heteroscedasticity. Using the generalized inference approach, we obtain the generalized p-values of two-sided hypotheses for the multi-dimensional location parameters and one-sided hypotheses for the scale parameters, respectively. Some frequentist properties in small-sample cases and large-sample cases are proven.     

Estimation for the parameters of the generalized half-normal distribution

As an applicable and flexible lifetime model, the two-parameter generalized half-normal (GHN) distribution has been received wide attention in the field of reliability analysis and lifetime study. In this paper maximum likelihood estimates of the model parameters are discussed and we also proposed corresponding bias-corrected estimates. Unweighted and weighted least squares estimates for the parameters of the GHN distribution are also presented for comparison purpose. Moreover, the likelihood ratio test is provided as complementary. Simulation study and illustrative examples are provided to compare the performance of the proposed methods.     

Likelihood inference for the component lifetime distribution based on progressively censored parallel systems data

Point and interval estimators for the scale parameter of the component lifetime distribution of a k-component parallel system are obtained when the component lifetimes are assumed to be independently and identically exponentially distributed. We prove that the maximum likelihood estimator of the scale parameter based on progressively Type-II censored system lifetimes is unique and can be obtained by a fixed-point iteration procedure. In particular, we illustrate that the Newton–Raphson method does not converge for any initial value. Furthermore, exact confidence intervals are constructed by a transformation using normalized spacings and other component lifetime distributions including Weibull distribution are discussed.     

Some results on generalized ageing classes

In this paper we provide new results about generalized ageing classes on the excess lifetime of a renewal process. We also obtain some characterizations of generalized ageing classes by means of the residual life at random time.     

An extension of the generalized linear failure rate distribution

In this article, we introduce a new extension of the generalized linear failure rate (GLFR) distributions. It includes some well-known lifetime distributions such as extension of generalized exponential and GLFR distributions as special sub-models. In addition, it can have a constant, decreasing, increasing, upside-down bathtub (unimodal), and bathtub-shaped hazard rate function (hrf) depending on its parameters. We provide some of its statistical properties such as moments, quantiles, skewness, kurtosis, hrf, and reversible hrf. The maximum likelihood estimation of the parameters is also discussed. At the end, a real dataset is given to illustrate the usefulness of this new distribution in analyzing lifetime data.     

A Parametric Bootstrap Test for Two-Way ANOVA Model Without Interaction Under Heteroscedasticity

In this article we consider the two-way ANOVA model without interaction under heteroscedasticity. For the problem of testing equal effects of factors, we propose a parametric bootstrap (PB) approach and compare it with existing the generalized F (GF) test. The Type I error rates and powers of the tests are evaluated using Monte Carlo simulation. Our studies show that the PB test performs better than the GF test. The PB test performs very satisfactorily even for small samples while the GF test exhibits poor Type I error properties when the number of factorial combinations or treatments goes up. It is also noted that the same tests can be used to test the significance of random effect variance component in a two-way mixed-effects model under unequal error variances.     

Deviance residuals in generalised log-gamma regression models with censored observations

In this article, we compare three residuals based on the deviance component in generalised log-gamma regression models with censored observations. For different parameter settings, sample sizes and censoring percentages, various simulation studies are performed and the empirical distribution of each residual is displayed and compared with the standard normal distribution. For all cases studied, the empirical distributions of the proposed residuals are in general symmetric around zero, but only a martingale-type residual presented negligible kurtosis for the majority of the cases studied. These studies suggest that the residual analysis usually performed in normal linear regression models can be straightforwardly extended for the martingale-type residual in generalised log-gamma regression models with censored data. A lifetime data set is analysed under log-gamma regression models and a model checking based on the martingale-type residual is performed.     

MODELING THE LIFETIME OF LONGITUDINAL ELEMENTS

In the study of the stochastic behaviour of the lifetime of an element as a function of its length, it is often observed that the failure time (or lifetime) decreases as the length increases. In probabilistic terms, such an idea can be expressed as follows. Let T be the lifetime of a specimen of length x, so the survival function, which denotes the probability that an element of length x survives till time t, will be given by S_T (t, x) = P(T > t/α(x), where α(x) is a monotonically decreasing function. In particular, it is often assumed that T has a Weibull distribution. In this paper, we propose a generalization of this Weibull model by assuming that the distribution of T is Generalized gamma (GG). Since the GG model contains the Weibull, Gamma and Lognormal models as special and limiting cases, a GG regression model is an appropriate tool for describing the size effect on the lifetime and for selecting among the embedded models. Maximum likelihood estimates are obtained for the GG regression model with α(x) = cx^b . As a special case this provide an alternative to the usual approach to estimation for the GG distribution which involves reparametrization. Related parametric inference issues are addressed and illustrated using two experimental data sets. Some discussion of censored data is also provided.     

Discriminating between the generalized Rayleigh and Weibull distributions: Some comparative studies

The generalized Rayleigh distribution was introduced and studied quite effectively in the literature. The closeness and separation between the distributions are extremely important for analyzing any lifetime data. In this spirit, both the generalized Rayleigh and Weibull distributions can be used for analyzing skewed datasets. In this article, we compare these two distributions based on the Fisher information measures and use it for discrimination purposes. It is evident that the Fisher information measures play an important role in separating between the distributions. The total information measures and the variances of the different percentile estimators are computed and presented. A real life dataset is analyzed for illustration purposes and a numerical comparison study is performed to assess our procedures in separating between these two distributions.     

Parametric Bootstrap Tests for Unbalanced Three-factor Nested Designs under Heteroscedasticity

In this article, we consider the three-factor unbalanced nested design model without the assumption of equal error variance. For the problem of testing “main effects” of the three factors, we propose a parametric bootstrap (PB) approach and compare it with the existing generalized F (GF) test. The Type I error rates of the tests are evaluated using Monte Carlo simulation. Our studies show that the PB test performs better than the generalized F-test. The PB test performs very satisfactorily even for small samples while the GF test exhibits poor Type I error properties when the number of factorial combinations or treatments goes up. It is also noted that the same tests can be used to test the significance of the random effect variance component in a three-factor mixed effects nested model under unequal error variances.     

Inferences on the Among-Group Variance Component in Unbalanced Heteroscedastic One-Fold Nested Design

This article studies the hypothesis testing and interval estimation for the among-group variance component in unbalanced heteroscedastic one-fold nested design. Based on the concepts of generalized p-value and generalized confidence interval, tests and confidence intervals for the among-group variance component are developed. Furthermore, some simulation results are presented to compare the performance of the proposed approach with those of existing approaches. It is found that the proposed approach and one of the existing approaches can maintain the nominal confidence level across a wide array of scenarios, and therefore are recommended to use in practical problems. Finally, a real example is illustrated.     

Performance of Confidence Intervals in Regression Models with Unbalanced One-Fold Nested Error Structures

Abstract

In this article we consider the problem of constructing confidence intervals for a linear regression model with unbalanced nested error structure. A popular approach is the likelihood-based method employed by PROC MIXED of SAS. In this article, we examine the ability of MIXED to produce confidence intervals that maintain the stated confidence coefficient. Our results suggest that intervals for the regression coefficients work well, but intervals for the variance component associated with the primary level cannot be recommended. Accordingly, we propose alternative methods for constructing confidence intervals on the primary level variance component. Computer simulation is used to compare the proposed methods. A numerical example and SAS code are provided to demonstrate the methods.     

Fitting Distributions with the Polyhazard Model with Dependence

The polyhazard model with dependent causes, first introduced to fit lifetime data, generalized the traditional polyhazard model by allowing the latent causes of failure to be dependent by using copula functions. When modeling lifetime data, marginal distributions are supported on the positive reals. Dropping this restriction, the method generates a rich family of univariate distributions with asymmetries and multiple modes. We show that this new family of distributions is able to approximate other distributions proposed in the literature, such as the generalized beta-generated distributions. These distributions are fitted to three real data sets.     

Analysis of left censored data from the generalized exponential distribution

The generalized exponential distribution proposed by Gupta and Kundu [Gupta, R.D and Kundu, D., 1999, Generalized exponential distributions. Australian and New Zealand Journal of Statistics, 41(2), 173–188.] is an important lifetime distribution in survival analysis. In this paper, we consider the maximum likelihood estimation procedure of the parameters of the generalized exponential distribution when the data are left censored. We obtain the maximum likelihood estimators of the unknown para-meters and the Fisher information matrix. Simulation studies are carried out to observe the performance of the estimators in small sample.     

Bivariate Birnbaum-Saunders accelerated lifetime model: estimation and diagnostic analysis

In this paper, we discuss the bivariate Birnbaum-Saunders accelerated lifetime model, in which we have modeled the dependence structure of bivariate survival data through the use of frailty models. Specifically, we propose the bivariate model Birnbaum-Saunders with the following frailty distributions: gamma, positive stable and logarithmic series. We present a study of inference and diagnostic analysis for the proposed model, more concisely, are proposed a diagnostic analysis based in local influence and residual analysis to assess the fit model, as well as, to detect influential observations. In this regard, we derived the normal curvatures of local influence under different perturbation schemes and we performed some simulation studies for assessing the potential of residuals to detect misspecification in the systematic component, the presence in the stochastic component of the model and to detect outliers. Finally, we apply the methodology studied to real data set from recurrence in times of infections of 38 kidney patients using a portable dialysis machine, we analyzed these data considering independence within the pairs and using the bivariate Birnbaum-Saunders accelerated lifetime model, so that we could make a comparison and verify the importance of modeling dependence within the times of infection associated with the same patient.     

Infant mortality model for lifetime data

In this paper we introduce a parametric model for handling lifetime data where an early lifetime can be related to the infant-mortality failure or to the wear processes but we do not know which risk is responsible for the failure. The maximum likelihood approach and the sampling-based approach are used to get the inferences of interest. Some special cases of the proposed model are studied via Monte Carlo methods for size and power of hypothesis tests. To illustrate the proposed methodology, we introduce an example consisting of a real data set.