共查询到20条相似文献,搜索用时 15 毫秒
1.
The Significance Analysis of Microarrays (SAM; Tusher et al., 2001) method is widely used in analyzing gene expression data while controlling the FDR by using resampling-based procedure in the microarray setting. One of the main components of the SAM procedure is the adjustment of the test statistic. The introduction of the fudge factor to the test statistic aims at deflating the large value of test statistics due to the small standard error of gene-expression. Lin et al. (2008) pointed out that the fudge factor does not effectively improve the power and the control of the FDR as compared to the SAM procedure without the fudge factor in the presence of small variance genes. Motivated by the simulation results presented in Lin et al. (2008), in this article, we extend our study to compare several methods for choosing the fudge factor in the modified t-type test statistics and use simulation studies to investigate the power and the control of the FDR of the considered methods. 相似文献
2.
In a recent article, Pedeli and Karlis (2010) examined the extension of the classical Integer–valued Autoregressive (INAR) model to the bivariate case. In the present article, we examine estimation methods for the case of bivariate Poisson innovations. This is a simple extension of the classical INAR model allowing for two discrete valued time series to be correlated. Properties of different estimators are given. We also compare their properties via a small simulation experiment. Extensions to incorporate covariate information is discussed. A real data application is also provided. 相似文献
3.
We consider a new generalization of the skew-normal distribution introduced by Azzalini (1985). We denote this distribution Beta skew-normal (BSN) since it is a special case of the Beta generated distribution (Jones, 2004). Some properties of the BSN are studied. We pay attention to some generalizations of the skew-normal distribution (Bahrami et al., 2009; Sharafi and Behboodian, 2008; Yadegari et al., 2008) and to their relations with the BSN. 相似文献
4.
Pao-Sheng Shen 《统计学通讯:模拟与计算》2013,42(3):603-612
In this article, we consider the M-estimators for the linear regression model when both response and covariate variables are subject to double censoring. The proposed estimators are constructed as some functional of three types of estimators for a bivariate survival distribution. The first two estimators are the generalizations of the Campbell and Földes (1982) and Dabrowska (1988) estimators proposed by Shen (2009). The third estimator is the generalization of the Prentice and Cai (1992) estimator. The consistency of the proposed M-estimators is established. A simulation study is conducted to investigate the performance of the proposed estimators. Furthermore, the simple bootstrap methods are used to estimate standard deviations and construct interval estimators. 相似文献
5.
In this article, another version of the generalized exponential geometric distribution different to that of Silva et al. (2010) is proposed. This new three-parameter lifetime distribution with decreasing, increasing, and bathtub failure rate function is created by compounding the generalized exponential distribution of Gupta and Kundu (1999) with a geometric distribution. Some basic distributional properties, moment-generating function, rth moment, and Rényi entropy of the new distribution are studied. The model parameters are estimated by the maximum likelihood method and the asymptotic distribution of estimators is discussed. Finally, an application of the new distribution is illustrated using the two real data sets. 相似文献
6.
Feng-Shou Ko 《统计学通讯:理论与方法》2013,42(15):2681-2698
A proposed method based on frailty models is used to identify longitudinal biomarkers or surrogates for a multivariate survival. This method is an extention of earlier models by Wulfsohn and Tsiatis (1997) and Song et al. (2002). In this article, similar to Henderson et al. (2002), a joint likelihood function combines the likelihood functions of the longitudinal biomarkers and the multivariate survival times. We use simulations to explore how the number of individuals, the number of time points per individual and the functional form of the random effects from the longitudianl biomarkers influence the power to detect the association of a longitudinal biomarker and the multivariate survival time. The proposed method is illustrate by using the gastric cancer data. 相似文献
7.
This paper addresses a generalization of the bivariate Cauchy distribution discussed by Fang et al. (1990), derived from a trivariate normal distribution with a general correlation matrix. We obtain explicit expressions for the joint distribution function and joint density function, and show that they reduce in a special case to the corresponding expressions of Fang et al. (1990). Finally, we show that this generalized distribution is useful in determining the orthant probability of a bivariate skew-normal distribution of Azzalini and Dalla Valle (1996). 相似文献
8.
A generalization of the Gaver and Lewis (1980) model of first-order autoregressive process with marginals as bivariate Mittag–Leffler distribution is obtained. A necessary and sufficient condition for stationarity of the process is established. Autoregressive process with marginals follow bivariate discrete Mittag–Leffler distribution is also developed. The unknown parameters of the processes are estimated and some numerical results of the estimations are given. 相似文献
9.
AbstractIn this article, we improvise Singh and Grewal (2013) and Hussain et al. (2016) techniques by introducing a new two-stage randomization response process. Using the proposed new technique, we achieve better efficiency and increasing protection of privacy of respondents than the Kuk (1990), Singh and Grewal (2013) and Hussain et al. (2016) models. The relative efficiency and protection of the respondents of the proposed two-stage randomization device have been investigated through simulation study, and the situations are reported where the proposed estimator performs better than its competitors. The SAS code used to investigate the performance of the proposed strategy are also provided. 相似文献
10.
In an earlier article (Bai et al., 1999), the problem of simultaneous estimation of the number of signals and frequencies of multiple sinusoids is considered in the case that some observations are missing. The number of signals is estimated with an information theoretic criterion and the frequencies are estimated with eigenvariation linear prediction. Asymptotic properties of the procedure are investigated but the Monte Carlo simulation is not performed. In this article, a slightly different but scale invariant criterion for detection is proposed and the estimation of frequencies remains the same. Asymptotic properties of this new procedure are provided. Monte Carlo Simulation for both procedures is carried out. Furthermore, comparison on the real signals is also given. 相似文献
11.
Soo Hak Sung 《统计学通讯:理论与方法》2013,42(9):1663-1674
A complete convergence theorem for an array of rowwise independent random variables was established by Sung et al. (2005). This result has been generalized and extended by Kruglov et al. (2006) and Chen et al. (2007). In this article, we extend the results of Sung et al. (2005), Kruglov et al. (2006), and Chen et al. (2007) to an array of dependent random variables satisfying Hoffmann-Jørgensen type inequalities. 相似文献
12.
Shesh N. Rai Jianmin Pan Xiaobin Yuan Jianguo Sun Melissa M. Hudson Deo K. Srivastava 《统计学通讯:理论与方法》2013,42(17):3117-3133
New drug discovery in the pediatrics has dramatically improved survival, but with long- term adverse events. This motivates the examination of adverse outcomes such as long-term toxicity in a phase IV trial. An ideal approach to monitor long-term toxicity is to systematically follow the survivors, which is generally not feasible. Instead, cross-sectional surveys are conducted in Hudson et al. (2007), with one of the objectives to estimate the cumulative incidence rates along with specific interest in fixed-term (5 or 10 year) rates. We present inference procedures based on current status data to our motivating example with very interesting findings. 相似文献
13.
The main object of this article is to propose an extension of the tobit model for which the error distribution follows the power-normal distribution (Gupta and Gupta, 2008). Inference is dealt with by using the likelihood approach. Simulation studies and application to a real data set are used to demonstrate the usefulness of the extension. 相似文献
14.
Two types of estimates of process level, namely repeated median estimates (Siegel, 1982) and full online estimates (Gather et al., 2006) based on repeated median filters, are used to develop control charts. The distributional properties of the estimates are studied using simulation and these are found to closely follow normal distribution. The repeated median being robust against outliers with asymptotically 50% breakdown value and having small standard deviation is found to be useful as a basis for monitoring process averages. The control charts using repeated median estimates have been recommended for general use. 相似文献
15.
Jean-François Quessy 《统计学通讯:理论与方法》2013,42(19):3510-3531
Population and sample versions of Kendall and Spearman measures of association suitable for multivariate ordinal data are defined. The latter generalize the indices of dependence of Ruymgaart and van Zuijlen (1978), Joe (1990), and Schmid and Schmidt (2007) by allowing atoms in the underlying distribution. The representation of the proposed empirical measures as U-statistics enables to establish their asymptotic normality under general distributions. A special attention is given to tests of independence for multivariate ordinal data, where the power of the new methodologies are investigated under fixed and contiguous alternatives. 相似文献
16.
For each positive integer k, a set of k-principal points of a distribution is the set of k points that optimally represent the distribution in terms of mean squared distance. However, explicit form of k-principal points is often difficult to obtain. Hence a theorem established by Tarpey et al. (1995) has been influential in the literature, which states that when the distribution is elliptically symmetric, any set of k-principal points is in the linear subspace spanned by some principal eigenvectors of the covariance matrix. This theorem is called a “principal subspace theorem”. Recently, Yamamoto and Shinozaki (2000b) derived a principal subspace theorem for 2-principal points of a location mixture of spherically symmetric distributions. In their article, the ratio of mixture was set to be equal. This article derives a further result by considering a location mixture with unequal mixture ratio. 相似文献
17.
This paper deals with Dynamic Stochastic General Equilibrium (DSGE) models under a multivariate student-t distribution for the structural shocks. Based on the solution algorithm of Klein (2000) and the gamma-normal representation of the t-distribution, the TaRB-MH algorithm of Chib and Ramamurthy (2010) is used to estimate the model. A technique for estimating the marginal likelihood of the DSGE student-t model is also provided. The methodologies are illustrated first with simulated data and then with the DSGE model of Ireland (2004) where the results support the t-error model in relation to the Gaussian model. 相似文献
18.
In this article, we consider the progressive Type II right censored sample from Pareto distribution. We introduce a new approach for constructing the simultaneous confidence interval of the unknown parameters of this distribution under progressive censoring. A Monte Carlo study is also presented for illustration. It is shown that this confidence region has a smaller area than that introduced by Ku? and Kaya (2007). 相似文献
19.
In contrast with the classical Cramér–Lundberg model where the premium process is a linear function of time, we consider the ruin probability under the risk model where the aggregate premium consists of both a compound Poisson process and a linear process of time. Moreover, a constant interest force is also taken into account in our model. We restrict ourselves to the case where the claim size is heavy-tailed, i.e., the equilibrium distribution function of the claim size belongs to a wide subclass of the subexponential distribution. An asymptotic formula for the ruin probability is obtained by using the similar method of Kalashnikov and Konstantinides (2000). The asymptotic formula we get here is the same as the one in Asmussen (1998), Klüppelberg and Stadtmüller (1998), and Kalashnikov and Konstantinides (2000) which did not consider the stochastic premium. 相似文献
20.
Here, we apply the smoothing technique proposed by Chaubey et al. (2007) for the empirical survival function studied in Bagai and Prakasa Rao (1991) for a sequence of stationary non-negative associated random variables.The derivative of this estimator in turn is used to propose a nonparametric density estimator. The asymptotic properties of the resulting estimators are studied and contrasted with some other competing estimators. A simulation study is carried out comparing the recent estimator based on the Poisson weights (Chaubey et al., 2011) showing that the two estimators have comparable finite sample global as well as local behavior. 相似文献