Sensitivity analysis of partially linear models with response missing at random

This article investigates case-deletion influence analysis via Cook’s distance and local influence analysis via conformal normal curvature for partially linear models with response missing at random. Local influence approach is developed to assess the sensitivity of parameter and nonparametric estimators to various perturbations such as case-weight, response variable, explanatory variable, and parameter perturbations on the basis of semiparametric estimating equations, which are constructed using the inverse probability weighted approach, rather than likelihood function. Residual and generalized leverage are also defined. Simulation studies and a dataset taken from the AIDS Clinical Trials are used to illustrate the proposed methods.     

Maximum-likelihood estimation and influence analysis in multivariate skew-normal reproductive dispersion mixed models for longitudinal data

Various mixed models were developed to capture the features of between- and within-individual variation for longitudinal data under the normality assumption of the random effect and the within-individual random error. However, the normality assumption may be violated in some applications. To this end, this article assumes that the random effect follows a skew-normal distribution and the within-individual error is distributed as a reproductive dispersion model. An expectation conditional maximization (ECME) algorithm together with the Metropolis-Hastings (MH) algorithm within the Gibbs sampler is presented to simultaneously obtain estimates of parameters and random effects. Several diagnostic measures are developed to identify the potentially influential cases and assess the effect of minor perturbation to model assumptions via the case-deletion method and local influence analysis. To reduce the computational burden, we derive the first-order approximations to case-deletion diagnostics. Several simulation studies and a real data example are presented to illustrate the newly developed methodologies.     

Influence on tests with focus on linear models

To assess the influence of single observations on the parameter estimates, case-deletion diagnostics are commonly used in linear regression models; one example is Cook's distance. For nested parametric models we consider a deletion diagnostic for evaluating the influence of a single observation on the likelihood ratio (LR) test. In order to have a common scale as reference, the asymptotic distribution of the diagnostic is derived and the values of the diagnostic are converted to percentiles. We focus on linear models and general linear models, and in these cases explicit results are derived. The performance of the diagnostic is explored in two small bench mark examples from linear regression and in a larger linear mixed model example.     

On local influence for elliptical linear models

The local influence method plays an important role in regression diagnostics and sensitivity analysis. To implement it, we need the Delta matrix for the underlying scheme of perturbations, in addition to the observed information matrix under the postulated model. Galea, Paula and Bolfarine (1997) has recently given the observed information matrix and the Delta matrix for a scheme of scale perturbations and has assessed of local influence for elliptical linear regression models. In the present paper, we consider the same elliptical linear regression models. We study the schemes of scale, predictor and response perturbations, and obtain their corresponding Delta matrices, respectively. To illustrate the methodology for assessment of local influence for these schemes and the implementation of the obtained results, we give an example.     

Diagnostics for generalized Poisson regression models with errors in variables

In this paper, we develop diagnostic methods for generalized Poisson regression (GPR) models with errors in variables based on the corrected likelihood. The one-step approximations of the estimates in the case-deletion model are given and case-deletion and local influence measures are presented. Meanwhile, based on a corrected score function, the testing statistics for the significance of dispersion parameters in GPR models with measurement errors are investigated. Finally, illustration of our methodology is given through numerical examples.     

Influence Diagnostics for a Skew Extension of the Grubbs Measurement Error Model

Influence diagnostics methods are extended in this article to the Grubbs model when the unknown quantity x (latent variable) follows a skew-normal distribution. Diagnostic measures are derived from the case-deletion approach and the local influence approach under several perturbation schemes. The observed information matrix to the postulated model and Delta matrices to the corresponding perturbed models are derived. Results obtained for one real data set are reported, illustrating the usefulness of the proposed methodology.     

Local influence on bandwidth estimation for kernel smoothing

This paper examines the problem of assessing local influence on the optimal bandwidth estimation in kernel smoothing based on cross validation. The bandwidth for kernel smoothing plays an important role in the model fitting and is often estimated using the cross-validation criterion. Following the argument of the second-order approach to local influence suggested by Wu and Luo (1993), we develop a new diagnostic statistic to examine the local influence of the observations on the estimation of the optimal bandwidth, where the perturbation may belong to one of three schemes. These are the response perturbation, the perturbation in the explanatory variable, and the case-weight

perturbation. The proposed diagnostic is nonparametric and is capable of identifying influential observations with strong influence on the bandwidth estimation. An example is presented to illustrate the application of the proposed diagnostic, and the usefulness of the nonparametric approach is illustrated in comparison with some other approaches to the assessment of local influence     

On influence diagnostic in univariate elliptical linear regression models

We discuss in this paper the assessment of local influence in univariate elliptical linear regression models. This class includes all symmetric continuous distributions, such as normal, Student-t, Pearson VII, exponential power and logistic, among others. We derive the appropriate matrices for assessing the local influence on the parameter estimates and on predictions by considering as influence measures the likelihood displacement and a distance based on the Pearson residual. Two examples with real data are given for illustration.     

Influence diagnostics in the tobit censored response model

In this article, we develop influence diagnostic tools for the tobit model. Specifically, we discuss global influence methods based on the Cook distance and residuals with envelopes, and total and conformal local influence techniques. In order to analyze the sensitivity of the maximum likelihood estimators of the parameters of the model to small perturbations on the assumptions of the model and/or data, we consider several perturbation schemes, such as case-weight and response perturbations. Finally, we illustrate the developed methodology by means of a real data set.     

Sensitivity of the portmanteau statistic in time series modeling

The portmanteau statistic is commonly used for testing goodness-of-fit of time series models. However, this lack of fit test may depend on one or several atypical observations in the series. We investigate the sensitivity of the portmanteau statistic in the presence of additive outliers. Diagnostics are developed to assess both local and global influence. Three practical examples demonstrate the usefulness of the proposed diagnostics.     

Influence analysis of additive mixed-effects nonlinear regression models via EM algorithm

This paper presents a unified method for influence analysis to deal with random effects appeared in additive nonlinear regression models for repeated measurement data. The basic idea is to apply the Q-function, the conditional expectation of the complete-data log-likelihood function obtained from EM algorithm, instead of the observed-data log-likelihood function as used in standard influence analysis. Diagnostic measures are derived based on the case-deletion approach and the local influence approach. Two real examples and a simulation study are examined to illustrate our methodology.     

Detection of influential observations in nonlinear reproductive dispersion models

A robust case-deletion diagnostic which could avoid masking is presented for nonlinear reproductive dispersion models (NRDM) (Jorgensen, 1997) that include generalized linear models and exponential family nonlinear models as special cases. Based on the second-order approximation of log-likelihood displacement and Poon & Poon's (1999) conformal normal curvature, a measure of local influence ranging from 0 to 1 is constructed. An example illustrates application of the techniques.     

Bayesian estimation and case influence diagnostics for the zero-inflated negative binomial regression model

In recent years, there has been considerable interest in regression models based on zero-inflated distributions. These models are commonly encountered in many disciplines, such as medicine, public health, and environmental sciences, among others. The zero-inflated Poisson (ZIP) model has been typically considered for these types of problems. However, the ZIP model can fail if the non-zero counts are overdispersed in relation to the Poisson distribution, hence the zero-inflated negative binomial (ZINB) model may be more appropriate. In this paper, we present a Bayesian approach for fitting the ZINB regression model. This model considers that an observed zero may come from a point mass distribution at zero or from the negative binomial model. The likelihood function is utilized to compute not only some Bayesian model selection measures, but also to develop Bayesian case-deletion influence diagnostics based on q-divergence measures. The approach can be easily implemented using standard Bayesian software, such as WinBUGS. The performance of the proposed method is evaluated with a simulation study. Further, a real data set is analyzed, where we show that ZINB regression models seems to fit the data better than the Poisson counterpart.     

Influence diagnostics in nonlinear reproductive dispersion mixed models

The class of nonlinear reproductive dispersion mixed models (NRDMMs) is an extension of nonlinear reproductive dispersion models and generalized linear mixed models. This paper discusses the influence analysis of the model based on Laplace approximation. The equivalence of case-deletion models and mean-shift outlier models in NRDMMs is investigated, and some diagnostic measures are proposed via the case-deletion method. We also investigate the assessment of local influence of various perturbation schemes. The proposed method is illustrated with an example.     

Influence diagnostics in constrained general linear models

ABSTRACT

Constrained general linear models (CGLMs) have wide applications in practice. Similar to other data analysis, the identification of influential observations that may be potential outliers is an important step beyond in the CGLMs. We develop multiple case-deletion diagnostics for detecting influential observations in the CGLMs. The diagnostics are functions of basic building blocks: studentized residuals, error contrast matrix, and the inverse of the response variable covariance matrix. The basic building blocks are computed only once from the complete data analysis and provide information on the influence of the data on different aspects of the model fit. Computational formulas are given which make the procedures feasible. An illustrative example with a real data set is also reported.     

Assessing case influence on confidence intervals in nonlinear regression

Diagnostic techniques are proposed for assessing the influence of individual cases on confidence intervals in nonlinear regression. The technique proposed uses the method of profile t-plots applied to the case-deletion model. The effect of the geometry of the statistical model on the influence measures is assessed, and an algorithm for computing case-deleted confidence intervals is described. This algorithm provides a direct method for constructing a simple diagnostic measure based on the ratio of the lengths of confidence intervals. The generalization of these methods to multiresponse models is discussed.     

Case-deletion Influence Measures for the Data from Multivariate t Distributions

For the data from multivariate t distributions, it is very hard to make an influence analysis based on the probability density function since its expression is intractable. In this paper, we present a technique for influence analysis based on the mixture distribution and EM algorithm. In fact, the multivariate t distribution can be considered as a particular Gaussian mixture by introducing the weights from the Gamma distribution. We treat the weights as the missing data and develop the influence analysis for the data from multivariate t distributions based on the conditional expectation of the complete-data log-likelihood function in the EM algorithm. Several case-deletion measures are proposed for detecting influential observations from multivariate t distributions. Two numerical examples are given to illustrate our methodology.     

Local influence diagnostics for incomplete overdispersed longitudinal counts

We develop local influence diagnostics to detect influential subjects when generalized linear mixed models are fitted to incomplete longitudinal overdispersed count data. The focus is on the influence stemming from the dropout model specification. In particular, the effect of small perturbations around an MAR specification are examined. The method is applied to data from a longitudinal clinical trial in epileptic patients. The effect on models allowing for overdispersion is contrasted with that on models that do not.     

Influence Measures Based on Cressie-Read Divergence Measures in Multivariate Linear Model

We define a new family of influence measures based on the divergence measures, in the multivariate general linear model. Influence measures are obtained by quantifying the divergence between the sample distribution of an estimate obtained with all the observations and the sample distribution of the same estimate obtained without any observation. This approach is applied to best linear unbiased estimates of estimable functions. Therefore, these diagnostics can be applied to every statistical multivariate technique that can be formulated like this kind of model. Some examples are considered to clarify the applicability of the introduced diagnostics.