Testing the homogeneity of several two‐parameter populations

The authors extend Fisher's method of combining two independent test statistics to test homogeneity of several two‐parameter populations. They explore two procedures combining asymptotically independent test statistics: the first pools two likelihood ratio statistics and the other, score test statistics. They then give specific results to test homogeneity of several normal, negative binomial or beta‐binomial populations. Their simulations provide evidence that in this context, Fisher's method performs generally well, even when the statistics to be combined are only asymptotically independent. They are led to recommend Fisher's test based on score statistics, since the latter have simple forms, are easy to calculate, and have uniformly good level properties.     

Testing hypotheses about the common mean of two normal populations

Two simple tests which allow for unequal sample sizes are considered for testing hypothesis for the common mean of two normal populations. The first test is an exact test of size a based on two available t-statistics based on single samples made exact through random allocation of α among the two available t-tests. The test statistic of the second test is a weighted average of two available t-statistics with random weights. It is shown that the first test is more efficient than the available two t-tests with respect to Bahadur asymptotic relative efficiency. It is also shown that the null distribution of the test statistic in the second test, which is similar to the one based on the normalized Graybill-Deal test statistic, converges to a standard normal distribution. Finally, we compare the small sample properties of these tests, those given in Zhou and Mat hew (1993), and some tests given in Cohen and Sackrowitz (1984) in a simulation study. In this study, we find that the second test performs better than the tests given in Zhou and Mathew (1993) and is comparable to the ones given in Cohen and Sackrowitz (1984) with respect to power..     

Multivaritate two stage test based on ranks

A distribution free two stage test based on ranks for the multivariate two sample location problem is presented. The asymptotic distribution of the first and second stage test statistics is derived. Results of a Monte Carlo power study are used to compare the two stage test with the usual one stage test. A brief table of critical values is also presented. The test is illustrated by using data from an exercise study conducted by the Multipurpose Arthritis center.     

A test for bivariate two sample location problem

A consistent test for difference in locations between two bivariate populations is proposed, The test is similar as the Mann-Whitney test and depends on the exceedances of slopes of the two samples where slope for each sample observation is computed by taking the ratios of the observed values. In terms of the slopes, it reduces to a univariate problem, The power of the test has been compared with those of various existing tests by simulation. The proposed test statistic is compared with Mardia's(1967) test statistics, Peters-Randies(1991) test statistic, Wilcoxon's rank sum test. statistic and Hotelling' T² test statistic using Monte Carlo technique. It performs better than other statistics compared for small differences in locations between two populations when underlying population is population 7(light tailed population) and sample size 15 and 18 respectively. When underlying population is population 6(heavy tailed population) and sample sizes are 15 and 18 it performas better than other statistic compared except Wilcoxon's rank sum test statistics for small differences in location between two populations. It performs better than Mardia's(1967) test statistic for large differences in location between two population when underlying population is bivariate normal mixture with probability p=0.5, population 6, Pearson type II population and Pearson type VII population for sample size 15 and 18 .Under bivariate normal population it performs as good as Mardia' (1967) test statistic for small differences in locations between two populations and sample sizes 15 and 18. For sample sizes 25 and 28 respectively it performs better than Mardia's (1967) test statistic when underlying population is population 6, Pearson type II population and Pearson type VII population     

Empirical likelihood tests for two‐sample problems via nonparametric density estimation

The authors study the problem of testing whether two populations have the same law by comparing kernel estimators of the two density functions. The proposed test statistic is based on a local empirical likelihood approach. They obtain the asymptotic distribution of the test statistic and propose a bootstrap approximation to calibrate the test. A simulation study is carried out in which the proposed method is compared with two competitors, and a procedure to select the bandwidth parameter is studied. The proposed test can be extended to more than two samples and to multivariate distributions.     

A new test for two-sample location problem based on empirical distribution function

We propose a new test for testing the equality of location parameter of two populations based on empirical distribution function (ECDF). The test statistics is obtained as a power divergence between two ECDFs. The test is shown to be distribution free, and its null distribution is obtained. We conducted empirical power comparison of the proposed test with several other available tests in the literature. We found that the proposed test performs better than its competitors considered here under several population structures. We also used two real datasets to illustrate the procedure.     

TESTING HYPOTHESES ABOUT THE COMMON MEAN OF TWO NORMAL POPULATIONS

Three tests are considered concerning the common mean of two normal populations: (1) an F test based on a sample from one population, (2) a test based on the addition of the F statistics from independent samples from two popultions (proposed), and (3) a test based on the maximum of the F statistics from two independent samples from two populations. A condition under which test (2) is locally more powerful than test (1) is given. As the test statistic in test (2) does not follow a standard distribution, a formula for approximating the observed significance level is provided. A simulation study is used to compare the power of these tests.     

A modified chi-square test for testing equality of two multinomial populations against an order restricted alternative

A modified chi-square test for testing the equality of two multinomial populations against an order restricted alternative in one sample and two sample cases is constructed. The relation between the concepts of dependence by cM-square and stochastic ordering is established, The asymptotic distribution of the test statistic is the chi-bar-square type discussed by Robertson, Wright and Dykstra (1988). Simulations are used to compare the power of this test with the power of the likelihood ratio test of stochastic ordering of the two multinomial populations.     

Modified Wilcoxon–Mann–Whitney Test and Power Against Strong Null

The Wilcoxon–Mann–Whitney (WMW) test is a popular rank-based two-sample testing procedure for the strong null hypothesis that the two samples come from the same distribution. A modified WMW test, the Fligner–Policello (FP) test, has been proposed for comparing the medians of two populations. A fact that may be under-appreciated among some practitioners is that the FP test can also be used to test the strong null like the WMW. In this article, we compare the power of the WMW and FP tests for testing the strong null. Our results show that neither test is uniformly better than the other and that there can be substantial differences in power between the two choices. We propose a new, modified WMW test that combines the WMW and FP tests. Monte Carlo studies show that the combined test has good power compared to either the WMW and FP test. We provide a fast implementation of the proposed test in an open-source software. Supplementary materials for this article are available online.     

Extension of the log-rank test

For the comparison of two groups of survival times subject to censoring the log-rank test is widely used. The log-rank test is known to be asymptotically fully efficient for the proportional hazards alternatives. But if the ratio of the hazards changes, the log-rank test may not detect the difference between the two groups. In this article a new test procedure is proposed. Simulation results show that the proposed test procedure provides good power against alternatives, where the hazard ratio between the two groups changes across 1.     

Testing the Equality of Two Exponential Distributions

This paper proposes an overlapping-based test statistic for testing the equality of two exponential distributions with different scale and location parameters. The test statistic is defined as the maximum likelihood estimate of the Weitzman's overlapping coefficient, which estimates the agreement of two densities. The proposed test statistic is derived in closed form. Simulated critical points are generated for the proposed test statistic for various sample sizes and significance levels via Monte Carlo Simulations. Statistical powers of the proposed test are computed via simulation studies and compared to those of the existing Log likelihood ratio test.     

On equivalence of two variances of a bivariate normal vector

A test for assessing the equivalence of two variances of a bivariate normal vector is constructed. It is uniformly more powerful than the two one-sided tests procedure and the power improvement is substantial. Numerical studies show that it has a type I error close to the test level at most boundary points of the null hypothesis space. One can apply this test to paired difference experiments or 2×2 crossover designs to compare the variances of two populations with two correlated samples. The application of this test on bioequivalence in variability is presented. We point out that bioequivalence in intra-variability implies bioequivalence in variability, however, the latter has a larger power.     

Combining the t test and Wilcoxon's rank-sum test

In the two-sample location-shift problem, Student's t test or Wilcoxon's rank-sum test are commonly applied. The latter test can be more powerful for non-normal data. Here, we propose to combine the two tests within a maximum test. We show that the constructed maximum test controls the type I error rate and has good power characteristics for a variety of distributions; its power is close to that of the more powerful of the two tests. Thus, irrespective of the distribution, the maximum test stabilizes the power. To carry out the maximum test is a more powerful strategy than selecting one of the single tests. The proposed test is applied to data of a clinical trial.     

Bootstrap test for a structural break under possible heteroscedasticity

In this article, we consider the Wald test statistic for testing equality between the sets of regression coefficients in two linear regression models when the disturbance variances may possibly be unequal. This test can be also used as a test for a structural break. However, it is well known that the test based on the Wald test statistic suffers from severe size distortion in small sample when the disturbance variances of the two regression models are unequal. Our simulation results show that substantial improvements are made when the bootstrap methods are applied.     

Testing for the parametric component of partially linear EV models under random censorship

This paper investigates the hypothesis test of the parametric component in partially linear errors-in-variables (EV) model with random censorship. We construct two test statistics based on the difference of the corrected residual sum of squares and empirical likelihood ratio under the null and alternative hypotheses. It is shown that the limiting distributions of the proposed test statistics are both weighted sum of independent standard chi-squared distribution with one degree of freedom under the null hypothesis. Based on the adjusted test statistics, we further develop two new types of test procedures. Finite sample performance of the proposed test procedures is evaluated by extensive simulation studies.     

A jackknife-based versatile test for two-sample problems with right-censored data

For testing the equality of two survival functions, the weighted logrank test and the weighted Kaplan–Meier test are the two most widely used methods. Actually, each of these tests has advantages and defects against various alternatives, while we cannot specify in advance the possible types of the survival differences. Hence, how to choose a single test or combine a number of competitive tests for indicating the diversities of two survival functions without suffering a substantial loss in power is an important issue. Instead of directly using a particular test which generally performs well in some situations and poorly in others, we further consider a class of tests indexed by a weighted parameter for testing the equality of two survival functions in this paper. A delete-1 jackknife method is implemented for selecting weights such that the variance of the test is minimized. Some numerical experiments are performed under various alternatives for illustrating the superiority of the proposed method. Finally, the proposed testing procedure is applied to two real-data examples as well.     

Confidence Intervals for the Weighted Sum of Two Independent Binomial Proportions

Confidence intervals for the difference of two binomial proportions are well known, however, confidence intervals for the weighted sum of two binomial proportions are less studied. We develop and compare seven methods for constructing confidence intervals for the weighted sum of two independent binomial proportions. The interval estimates are constructed by inverting the Wald test, the score test and the Likelihood ratio test. The weights can be negative, so our results generalize those for the difference between two independent proportions. We provide a numerical study that shows that these confidence intervals based on large‐sample approximations perform very well, even when a relatively small amount of data is available. The intervals based on the inversion of the score test showed the best performance. Finally, we show that as for the difference of two binomial proportions, adding four pseudo‐outcomes to the Wald interval for the weighted sum of two binomial proportions improves its coverage significantly, and we provide a justification for this correction.     

Group sequential x2 statistic for testing the difference of two mean vectors in clinical trials

In this study we discuss the group sequential procedures for comparing two treatments based on multivariate observations in clinical trials. Also we suppose that a response vector on each of two treatments has a multivariate normal distribution with unknown covariance matrix. Then we propose a group sequential x² statistic in order to carry out repeated significance test for hypothesis of no difference between two population mean vectors. In order to realize the group sequential test where average sample number is reduced, we propose another modified group sequential x² statistic by extension of Jennison and Turnbull ( 1991 ). After construction of repeated confidence boundaries for making the repeated significance test, we compare two group sequential procedures based on two statistics regarding the average sample number and the power of the test in the simulations.     

A non-parametric maximum test for the Behrens–Fisher problem

Non-normality and heteroscedasticity are common in applications. For the comparison of two samples in the non-parametric Behrens–Fisher problem, different tests have been proposed, but no single test can be recommended for all situations. Here, we propose combining two tests, the Welch t test based on ranks and the Brunner–Munzel test, within a maximum test. Simulation studies indicate that this maximum test, performed as a permutation test, controls the type I error rate and stabilizes the power. That is, it has good power characteristics for a variety of distributions, and also for unbalanced sample sizes. Compared to the single tests, the maximum test shows acceptable type I error control.     

A bivariate signed rank test for two sample location problem

An affine-invariant signed rank test for the difference in location between two symmetric populations is proposed. The proposed test statistic is compared with Hotelling's T2 test statistic, Mardia's(1967)test statistic, Peters-Randles(1991) test statistic and Wilcoxon's rank sum test statistic using a Monte Carlo Study. It performs better than Mardia's test statistic under almost all populations considered. Under the bivariate normal distribution, it performs better than other test statistics compared for small differences in location between two populations except Hotelling's T2. It performs better than all statistics, including Hotelling's T , for sample size 15 when samples are drawn from Pearson type.