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1.
Abstract

In this article, we revisit the problem of fitting a mixture model under the assumption that the mixture components are symmetric and log-concave. To this end, we first study the nonparametric maximum likelihood estimation (MLE) of a monotone log-concave probability density. To fit the mixture model, we propose a semiparametric EM (SEM) algorithm, which can be adapted to other semiparametric mixture models. In our numerical experiments, we compare our algorithm to that of Balabdaoui and Doss (2018 Balabdaoui, F., and C. R. Doss. 2018. Inference for a two-component mixture of symmetric distributions under log-concavity. Bernoulli 24 (2):105371.[Crossref], [Web of Science ®] [Google Scholar], Inference for a two-component mixture of symmetric distributions under log-concavity. Bernoulli 24 (2):1053–71) and other mixture models both on simulated and real-world datasets.  相似文献   

2.
The purpose of this article is to investigate the predictive inference for responses from the location parameter mean as well as from the median given a doubly censored sample from the two-parameter Rayleigh model. The predictive results by Khan et al. (2010 Khan , H. M. R. , Provost , S. B. , Ashima , S. ( 2010 ). Predictive Inference from a Two-Parameter Rayleigh Life Model Given a Doubly Censored Sample . Commun. Statist. Theor. Meth. 39 ( 7 ): 12371246 .[Taylor & Francis Online], [Web of Science ®] [Google Scholar]) are used to obtain the predictive inference for responses from the median, where Khan et al. (2010 Khan , H. M. R. , Provost , S. B. , Ashima , S. ( 2010 ). Predictive Inference from a Two-Parameter Rayleigh Life Model Given a Doubly Censored Sample . Commun. Statist. Theor. Meth. 39 ( 7 ): 12371246 .[Taylor & Francis Online], [Web of Science ®] [Google Scholar]) obtained the future estimates from the mean. A numerical example representing 66 liver cancer patients is used for predictive analysis. It is concluded that the predictive inference from the median gives precise results as compared with the location parameter mean.  相似文献   

3.
This article generalizes results from Park et al. (1998 Park , B. U. , Sickles , R. C. , Simar , L. ( 1998 ). Stochastic frontiers: a semiparametric approach . J. Econometrics 84 : 273301 .[Crossref], [Web of Science ®] [Google Scholar]) and Adams et al. (1999 Adams , R. M. , Berger , A. N. , Sickles , R. C. ( 1999 ). Semiparametric approaches to stochastic panel frontiers with applications in the banking industry . J. Bus. Econ. Statist. 17 : 349358 .[Taylor & Francis Online] [Google Scholar]) on semiparametric efficient estimation of panel models. The form of semiparametric efficient estimators depends on the statistical assumptions imposed. Normality assumptions on the transitory error are sometimes inappropriate. We relax the normality assumption used in the articles above to derive more general semiparametric efficient estimators. These estimators are illustrated in a Monte Carlo simulation and an analysis of banking productivity.  相似文献   

4.
Extending the bifurcating autoregressive (BAR) process (cf. Cowan and Staudte, 1986 Cowan , R. , Staudte , R. G. ( 1986 ). The bifurcating autoregression model in cell lineage studies . Biometrics 42 : 769783 .[Crossref], [PubMed], [Web of Science ®] [Google Scholar]) to multi-casting (multi-splitting) data, Hwang and Choi (2009 Hwang , S. Y. , Choi , M. S. ( 2009 ). Modeling and large sample estimation for multi-casting autoregression . Statist. Prob. Lett. 79 : 19431950 .[Crossref], [Web of Science ®] [Google Scholar]) introduced multi-casting autoregression (MCAR, for short) defined on multi-casting tree structured data. This article is concerned with the case when the MCAR model is partially specified only through conditional mean and variance without directly imposing autoregressive (AR) structure. The resulting class of models will be referred to as P-MCAR (partially specified MCAR). The P-MCAR considerably enlarges the class of multi-casting models including (as special cases) MCAR, random coefficient MCAR, conditionally heteroscedastic multi-casting models and binomial-thinning processes. Moment structures for this broad P-MCAR class are investigated. Least squares (LS) estimation method is discussed and asymptotic relative efficiency (ARE) of the generalized-LS over ordinary-LS is obtained in a closed form. A simulation study is conducted to illustrate results.  相似文献   

5.
Double censoring arises when T represents an outcome variable that can only be accurately measured within a certain range, [L, U], where L and U are the left- and right-censoring variables, respectively. When L is always observed, we consider the empirical likelihood inference for linear transformation models, based on the martingale-type estimating equation proposed by Chen et al. (2002 Chen , K. , Jin , Z. , Ying , Z. ( 2002 ). Semiparametric analysis of transformation models with censored data . Biometrika 89 : 659668 .[Crossref], [Web of Science ®] [Google Scholar]). It is demonstrated that both the approach of Lu and Liang (2006 Lu , W. , Liang , Y. ( 2006 ). Empirical likelihood inference for linear transformation models . Journal of Multivariate Analysis 97 : 15861599 .[Crossref], [Web of Science ®] [Google Scholar]) and that of Yu et al. (2011 Yu , W. , Sun , Y. , Zheng , M. ( 2011 ). Empirical likelihood method for linear transformation models . Annals of the Institute of Statistical Mathematics 63 : 331346 .[Crossref], [Web of Science ®] [Google Scholar]) can be extended to doubly censored data. Simulation studies are conducted to investigate the performance of the empirical likelihood ratio methods.  相似文献   

6.
We evaluate the finite-sample behavior of different heteros-ke-das-ticity-consistent covariance matrix estimators, under both constant and unequal error variances. We consider the estimator proposed by Halbert White (HC0), and also its variants known as HC2, HC3, and HC4; the latter was recently proposed by Cribari-Neto (2004 Cribari-Neto , F. ( 2004 ). Asymptotic inference under heteroskedasticity of unknown form . Computat. Statist. Data Anal. 45 : 215233 .[Crossref], [Web of Science ®] [Google Scholar]). We propose a new covariance matrix estimator: HC5. It is the first consistent estimator to explicitly take into account the effect that the maximal leverage has on the associated inference. Our numerical results show that quasi-t inference based on HC5 is typically more reliable than inference based on other covariance matrix estimators.  相似文献   

7.
We introduce a score test to identify longitudinal biomarkers or surrogates for a time to event outcome. This method is an extension of Henderson et al. (2000 Henderson , R. , Diggle , P. , Dobson , A. ( 2000 ). Joint modelling of longitudinal measurements and event time data . Biostatistics 1 ( 4 ): 465480 .[Crossref], [PubMed] [Google Scholar], 2002 Henderson , R. , Diggle , P. , Dobson , A. ( 2002 ). Identification and efficacy of longitudinal markers for survival . Biostatistics 3 ( 1 ): 3350 .[Crossref], [PubMed], [Web of Science ®] [Google Scholar]). In this article, a score test is based on a joint likelihood function which combines the likelihood functions of the longitudinal biomarkers and the survival times. Henderson et al. (2000 Henderson , R. , Diggle , P. , Dobson , A. ( 2000 ). Joint modelling of longitudinal measurements and event time data . Biostatistics 1 ( 4 ): 465480 .[Crossref], [PubMed] [Google Scholar], 2002 Henderson , R. , Diggle , P. , Dobson , A. ( 2002 ). Identification and efficacy of longitudinal markers for survival . Biostatistics 3 ( 1 ): 3350 .[Crossref], [PubMed], [Web of Science ®] [Google Scholar]) assumed that the same random effect exists in the longitudinal component and in the Cox model and then they can derive a score test to determine if a longitudinal biomarker is associated with time to an event. We extend this work and our score test is based on a joint likelihood function which allows other random effects to be present in the survival function.

Considering heterogeneous baseline hazards in individuals, we use simulations to explore how the factors can influence the power of a score test to detect the association of a longitudinal biomarker and the survival time. These factors include the functional form of the random effects from the longitudinal biomarkers, in the different number of individuals, and time points per individual. We illustrate our method using a prothrombin index as a predictor of survival in liver cirrhosis patients.  相似文献   

8.
Huang (2010 Huang , K. C. ( 2010 ). Unbiased estimators of mean, variance and sensitivity level for quantitative characteristics in finite population sampling . Metrika 71 : 341352 .[Crossref], [Web of Science ®] [Google Scholar]) proposed an optional randomized response model using a linear combination scrambling which is a generalization of the multiplicative scrambling of Eichhorn and Hayre (1983 Eichhorn , B. H. , Hayre , L. S. ( 1983 ). Scrambled randomized response methods for obtaining sensitive quantitative data . J. Statist. Plann. Infer. 7 : 307316 .[Crossref], [Web of Science ®] [Google Scholar]) and the additive scrambling of Gupta et al. (2006, 2010). In this article, we discuss two main issues. (1) Can the Huang (2010 Huang , K. C. ( 2010 ). Unbiased estimators of mean, variance and sensitivity level for quantitative characteristics in finite population sampling . Metrika 71 : 341352 .[Crossref], [Web of Science ®] [Google Scholar]) model be improved further by using a two-stage approach?; (2) Does the linear combination scrambling provide any benefit over the additive scrambling of Gupta et al. (2010 Gupta , S. N. , Shabbir , J. , Sehra , S. ( 2010 ). Mean and sensitivity estimation in optional randomized response models . J. Statist. Plann. Infer. 140 : 28702874 .[Crossref], [Web of Science ®] [Google Scholar])? We will note that the answer to the first question is “yes” but the answer to the second question is “no.”  相似文献   

9.
A proposed method based on frailty models is used to identify longitudinal biomarkers or surrogates for a multivariate survival. This method is an extention of earlier models by Wulfsohn and Tsiatis (1997 Wulfsohn , M. S. , Tsiatis , A. A. ( 1997 ). A joint model for survival and longitudinal data measured with error . Biometrics 53 ( 1 ): 330339 .[Crossref], [PubMed], [Web of Science ®] [Google Scholar]) and Song et al. (2002 Song , X. , Davidian , M. , Tsiatis , A. A. ( 2002 ). A Semiparametric likelihood approach to joint modeling of longitudinal and time-to-event data . Biometrics 58 ( 4 ): 742753 .[Crossref], [PubMed], [Web of Science ®] [Google Scholar]). In this article, similar to Henderson et al. (2002 Henderson , R. , Diggle , P. J. , Dobson , A. ( 2002 ). Identification and efficacy of longitudinal markers for survival . Biostatistics 3 ( 1 ): 3350 .[Crossref], [PubMed], [Web of Science ®] [Google Scholar]), a joint likelihood function combines the likelihood functions of the longitudinal biomarkers and the multivariate survival times. We use simulations to explore how the number of individuals, the number of time points per individual and the functional form of the random effects from the longitudianl biomarkers influence the power to detect the association of a longitudinal biomarker and the multivariate survival time. The proposed method is illustrate by using the gastric cancer data.  相似文献   

10.
For the first time, we provide a matrix formula for second-order covariances of maximum likelihood estimates in heteroskedastic generalized linear models, thus generalizing the results of Cordeiro (2004 Cordeiro , G. M. ( 2004 ). Second-order covariance matrix of maximum likelihood estimates in generalized linear models . Statist. Probab. Lett. 66 : 153160 .[Crossref], [Web of Science ®] [Google Scholar]) and Cordeiro et al. (2006 Cordeiro , G. M. , Barroso , L. P. , Botter , D. A. (2006). Covariance matrix formula for generalized linear models with unknown dispersion. Commun. Statist. Theor. Meth. 35:113120.[Taylor & Francis Online], [Web of Science ®] [Google Scholar]) related to the generalized linear models with known and unknown dispersion parameter, respectively. The covariance matrix formula does not involve cumulants of log-likelihood derivatives and can be easily obtained using simple matrix operations. We apply our main result to a simple model. Some simulations show that the second-order covariances can be quite pronounced in small to moderate samples. The usual covariances of the maximum likelihood estimates can be corrected by these second-order covariances.  相似文献   

11.
In incident cohort studies, survival data often include subjects who have had an initiate event at recruitment and may potentially experience two successive events (first and second) during the follow-up period. Since the second duration process becomes observable only if the first event has occurred, left-truncation and dependent censoring arise if the two duration times are correlated. To confront the two potential sampling biases, Chang and Tzeng (2006 Chang , S.-H. , Tzeng , S.-J. (2006). Noparametric estimation of sojourn time distributions for truncated serial event data- a weight-adjusted approach. Lifetime Data Anal. 5367.[Crossref], [PubMed], [Web of Science ®] [Google Scholar]) provided an inverse-probability-weighted (IPW) approach for estimating the joint probability function of successive duration times. In this note, an alternative IPW approach is proposed. A simulation study is conducted to compare the two IPW approaches.  相似文献   

12.
This paper generalizes the cointegrating model of Phillips (1991 Phillips , P. C. B. ( 1991 ). Optimal inference in cointegrated systems . Econometrica 59 : 283306 .[Crossref], [Web of Science ®] [Google Scholar]) to allow for I (0), I (1) and I (2) processes. The model has a simple form that permits a wider range of I (2) processes than are usually considered, including a more flexible form of polynomial cointegration. Further, the specification relaxes restrictions identified by Phillips (1991 Phillips , P. C. B. ( 1991 ). Optimal inference in cointegrated systems . Econometrica 59 : 283306 .[Crossref], [Web of Science ®] [Google Scholar]) on the I (1) and I (2) cointegrating vectors and restrictions on how the stochastic trends enter the system. To date there has been little work on Bayesian I (2) analysis and so this paper attempts to address this gap in the literature. A method of Bayesian inference in potentially I (2) processes is presented with application to Australian money demand using a Jeffreys prior and a shrinkage prior.  相似文献   

13.
The Significance Analysis of Microarrays (SAM; Tusher et al., 2001 Tusher , V. G. , Tibshirani , R. , Chu , G. ( 2001 ). Significance analysis of microarrys applied to the ionizing radiation response . Proceedings of the National Academy of Sciences 98 : 51165121 .[Crossref], [PubMed], [Web of Science ®] [Google Scholar]) method is widely used in analyzing gene expression data while controlling the FDR by using resampling-based procedure in the microarray setting. One of the main components of the SAM procedure is the adjustment of the test statistic. The introduction of the fudge factor to the test statistic aims at deflating the large value of test statistics due to the small standard error of gene-expression. Lin et al. (2008 Lin , D. , Shkedy , Z. , Burzykowski , T. , Göhlmann , H. W. H. , De Bondt , A. , Perera , T. , Geerts , T. , Bijnens , L. ( 2008 ). Significance analysis of microarray (SAM) for comparisons of several treatments with one control . Biometric Journal, MCP 50 ( 5 ): 801823 .[Crossref], [PubMed], [Web of Science ®] [Google Scholar]) pointed out that the fudge factor does not effectively improve the power and the control of the FDR as compared to the SAM procedure without the fudge factor in the presence of small variance genes. Motivated by the simulation results presented in Lin et al. (2008 Lin , D. , Shkedy , Z. , Burzykowski , T. , Göhlmann , H. W. H. , De Bondt , A. , Perera , T. , Geerts , T. , Bijnens , L. ( 2008 ). Significance analysis of microarray (SAM) for comparisons of several treatments with one control . Biometric Journal, MCP 50 ( 5 ): 801823 .[Crossref], [PubMed], [Web of Science ®] [Google Scholar]), in this article, we extend our study to compare several methods for choosing the fudge factor in the modified t-type test statistics and use simulation studies to investigate the power and the control of the FDR of the considered methods.  相似文献   

14.
Consider a skewed population. Suppose an intelligent guess could be made about an interval that contains the population mean. There may exist biased estimators with smaller mean squared error than the arithmetic mean within such an interval. This article indicates when it is advisable to shrink the arithmetic mean towards a guessed interval using root estimators. The goal is to obtain an estimator that is better near the average of natural origins. An estimator proposed. This estimator contains the Thompson (1968 Thompson , J. R. ( 1968 ). Accuracy borrowing in the estimation of the mean by shrinkage towards an interval . J. Amer. Statist. Assoc. 63 : 953963 . [CSA] [CROSSREF] [Taylor & Francis Online], [Web of Science ®] [Google Scholar]) ordinary shrinkage estimator, the Jenkins et al. (1973 Jenkins , O. C. , Ringer , L. J. , Hartley , H. O. ( 1973 ). Root estimators . J Amer. Statist. Assoc. 68 : 414419 . [CSA] [CROSSREF] [Taylor & Francis Online], [Web of Science ®] [Google Scholar]) square-root estimator, and the arithmetic sample mean as special cases. The bias and the mean squared error of the proposed more general estimator is compared with the three special cases. Shrinkage coefficients that yield minimum mean squared error estimators are obtained. The proposed estimator is considerably more efficient than the three special cases. This remains true for highly skewed populations. The merits of the proposed shrinkage square-root estimator are supported by the results of numerical and simulation studies.  相似文献   

15.
We carried out a simulation study based on the methodology of Newcombe (1998 Newcombe , R. G. ( 1998 ). Interval estimation for the difference between independent proportions: comparison of eleven methods . Statist. Med. 17 : 873890 .[Crossref], [PubMed], [Web of Science ®] [Google Scholar]) to compare tests for the difference of two binomial proportions by applying different continuity corrections on saddlepoint approximation to tail probabilities. In this article, we proposed a new continuity correction based on the least common multiple of two sample sizes. We evaluated that the best test should have the actual Type I error rates that are, on the whole, closest to α, but not exceeding α, where α is nominal level of significance.  相似文献   

16.
Nonlinear heteroscedastic models are widely used in econometrics and statistical applications. We derive matrix formulae for the second-order biases of the maximum likelihood estimators of the parameters in the mean and variance response which generalize previous results by Cook et al. (1986 Cook , D. R. , Tsai , C. L. , Wei , B. C. ( 1986 ). Bias in nonlinear regression . Biometrika 73 : 615623 .[Crossref], [Web of Science ®] [Google Scholar]) and Cordeiro (1993 Cordeiro , G. M. ( 1993 ). Bartlett corrections and bias correction for two heteroscedastic regression models . Commun. Statist. Theor. Meth. 22 : 169188 .[Taylor & Francis Online], [Web of Science ®] [Google Scholar]). The biases of the estimators are easily obtained as vectors of regression coefficients from suitable weighted linear regressions. The practical use of such biases is illustrated in a simulation study and in an application to a real data set.  相似文献   

17.
ABSTRACT

This paper reviews and extends the literature on the finite sample behavior of tests for sample selection bias. Monte Carlo results show that, when the “multicollinearity problem” identified by Nawata (1993 Nawata , K. ( 1993 ). A note on the estimation of models with sample-selection biases . Economics Letters 42 : 1524 . [CSA] [CROSSREF] [Crossref], [Web of Science ®] [Google Scholar]) is severe, (i) the t-test based on the Heckman–Greene variance estimator can be unreliable, (ii) the Likelihood Ratio test remains powerful, and (iii) nonnormality can be interpreted as severe sample selection bias by Maximum Likelihood methods, leading to negative Wald statistics. We also confirm previous findings (Leung and Yu, 1996 Leung , S. F. , Yu , S. ( 1996 ). On the choice between sample selection and two-part models . Journal of Econometrics 72 : 197229 . [CSA] [CROSSREF] [Crossref], [Web of Science ®] [Google Scholar]) that the standard regression-based t-test (Heckman, 1979 Heckman , J. J. ( 1979 ). Sample selection bias as a specification error . Econometrica 47 : 153161 . [CSA] [Crossref], [Web of Science ®] [Google Scholar]) and the asymptotically efficient Lagrange Multiplier test (Melino, 1982 Melino , A. ( 1982 ). Testing for sample selection bias . Review of Economic Studies 49 : 151153 . [CSA] [Crossref], [Web of Science ®] [Google Scholar]), are robust to nonnormality but have very little power.  相似文献   

18.
In this article, we examine the performance of two newly developed procedures that jointly select the number of states and variables in Markov-switching models by means of Monte Carlo simulations. They are Smith et al. (2006 Smith , A. , Naik , P. A. , Tsai , C. ( 2006 ). Markov-switching model selection using Kullback–Leibler divergence . Journal of Econometrics 134 ( 2 ): 553577 .[Crossref], [Web of Science ®] [Google Scholar]) and Psaradakis and Spagnolo (2006 Psaradakis , Z. , Spagnolo , N. ( 2006 ). Joint determination of the state dimension and autoregressive order for models with Markov regime switching . Journal of Time Series Analysis 27 ( 2 ): 753766 .[Crossref], [Web of Science ®] [Google Scholar]), respectively. The former develops Markov switching criterion (MSC) designed specifically for Markov-switching models, while the latter recommends the use of standard complexity-penalised information criteria (BIC, HQC, and AIC) in joint determination of the state dimension and the autoregressive order of Markov-switching models. The Monte Carlo evidence shows that BIC outperforms MSC while MSC and HQC are preferable over AIC.  相似文献   

19.
In this article, we consider the M-estimators for the linear regression model when both response and covariate variables are subject to double censoring. The proposed estimators are constructed as some functional of three types of estimators for a bivariate survival distribution. The first two estimators are the generalizations of the Campbell and Földes (1982 Campbell, G. and Földes, A. 1982. “Large sample properties of nonparametric statistical inference”. In Nonparametric Statistical Inference., Edited by: Gnredenko, B. V., Puri, M. L. and Vineze, I. 103122. Amsterdam: North-Holland.  [Google Scholar]) and Dabrowska (1988 Dabrowska, D. M. 1988. Kaplan-Meier estimate on the plane. Annals of Statistics, 18: 14751489. [Crossref], [Web of Science ®] [Google Scholar]) estimators proposed by Shen (2009 Shen, P. S. 2009. Nonparametric estimation of the bivariate survival function one modified form of doubly censored data. Computational Statistics, 25: 203313. [Crossref], [Web of Science ®] [Google Scholar]). The third estimator is the generalization of the Prentice and Cai (1992 Prentice, R. L. and Cai, J. 1992. Covariance and survivor function estimation using censored multivariate failure time data. Biometrika, 79: 495512. [Crossref], [Web of Science ®] [Google Scholar]) estimator. The consistency of the proposed M-estimators is established. A simulation study is conducted to investigate the performance of the proposed estimators. Furthermore, the simple bootstrap methods are used to estimate standard deviations and construct interval estimators.  相似文献   

20.
We consider a new generalization of the skew-normal distribution introduced by Azzalini (1985 Azzalini , A. ( 1985 ). A class of distributions which includes the normal ones . Scand. J. Statis. 12 ( 2 ): 171178 .[Web of Science ®] [Google Scholar]). We denote this distribution Beta skew-normal (BSN) since it is a special case of the Beta generated distribution (Jones, 2004 Jones , M. C. ( 2004 ). Families of distributions of order statistics . Test 13 ( 1 ): 143 .[Crossref], [Web of Science ®] [Google Scholar]). Some properties of the BSN are studied. We pay attention to some generalizations of the skew-normal distribution (Bahrami et al., 2009 Bahrami , W. , Agahi , H. , Rangin , H. ( 2009 ). A two-parameter Balakrishnan skew-normal distribution . J. Statist. Res. Iran 6 : 231242 . [Google Scholar]; Sharafi and Behboodian, 2008 Sharafi , M. , Behboodian , J. ( 2008 ). The Balakrishnan skew-normal density . Statist. Pap. 49 : 769778 .[Crossref], [Web of Science ®] [Google Scholar]; Yadegari et al., 2008 Yadegari , I. , Gerami , A. , Khaledi , M. J. ( 2008 ). A generalization of the Balakrishnan skew-normal distribution . Statist. Probab. Lett. 78 : 11651167 .[Crossref], [Web of Science ®] [Google Scholar]) and to their relations with the BSN.  相似文献   

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