共查询到20条相似文献,搜索用时 31 毫秒
1.
Feng-Shou Ko 《统计学通讯:理论与方法》2013,42(15):2681-2698
A proposed method based on frailty models is used to identify longitudinal biomarkers or surrogates for a multivariate survival. This method is an extention of earlier models by Wulfsohn and Tsiatis (1997) and Song et al. (2002). In this article, similar to Henderson et al. (2002), a joint likelihood function combines the likelihood functions of the longitudinal biomarkers and the multivariate survival times. We use simulations to explore how the number of individuals, the number of time points per individual and the functional form of the random effects from the longitudianl biomarkers influence the power to detect the association of a longitudinal biomarker and the multivariate survival time. The proposed method is illustrate by using the gastric cancer data. 相似文献
2.
Cibele Queiroz da-Silva Eduardo G. Martins Vinícius Bonato Sérgio Furtado dos Reis 《统计学通讯:模拟与计算》2013,42(4):816-828
We develop a series of Bayesian statistical models for estimating survival of a neotropic didelphid marsupial, the Brazilian gracile mouse opossum (Gracilinanus microtarsus). These models are based on the Cormack–Jolly–Seber model (Cormack, 1964; Jolly 1965; Seber 1965) with both survival and recapture rates expressed as a function of covariates using a logit link. The proposed models allow taking into account heterogeneity in capture probability caused by the existence of different groups of individuals in the population. The models were applied to two cohorts (Cohort, 2000, 2001) with the first one including 14 and the second one 15 sampling occasions. The best models for each of the cohorts indicate that G. microtarsus is best described as partially semelparous, a condition in which mortality after the first mating is high but graded over time, with a fraction of males surviving for a second breeding season (Boonstra, 2005). 相似文献
3.
Pao-sheng Shen 《统计学通讯:理论与方法》2013,42(20):3319-3328
The complication in analyzing tumor data is that the tumors detected in a screening program tend to be slowly progressive tumors, which is the so-called length-biased sampling that is inherent in screening studies. Under the assumption that all subjects have the same tumor growth function, Ghosh (2008) developed estimation procedures for proportional hazards model. In this article, by modeling growth function as a function of covariates, we demonstrate that Ghosh (2008)'s approach can be extended to the case when each subject has a specific growth function. A simulation study is conducted to demonstrate the potential usefulness of the proposed estimators for the regression parameters in the proportional and additive hazards model. 相似文献
4.
Olivier Darné 《统计学通讯:模拟与计算》2013,42(5):1037-1050
Unit root tests with structural break developed by Zivot and Andrews (1992) and Perron and Rodriguez (2003) in the presence of additive outliers and breaks are studied by simulation experiments. The results show that the Zivot–Andrews test appears to have size distortions due to the additive outliers whereas the Perron–Rodriguez test exhibits good properties of size and power. However, the two tests are biased when a second break is present but not taken into account. Furthermore, these endogenous break unit root tests tend to determine the break point incorrectly at one period behind the true break point, leading to spurious rejections of the unit root null hypothesis. 相似文献
5.
This article presents results concerning the performance of both single equation and system panel cointegration tests and estimators. The study considers the tests developed in Pedroni (1999, 2004), Westerlund (2005), Larsson et al. (2001), and Breitung (2005) and the estimators developed in Phillips and Moon (1999), Pedroni (2000), Kao and Chiang (2000), Mark and Sul (2003), Pedroni (2001), and Breitung (2005). We study the impact of stable autoregressive roots approaching the unit circle, of I(2) components, of short-run cross-sectional correlation and of cross-unit cointegration on the performance of the tests and estimators. The data are simulated from three-dimensional individual specific VAR systems with cointegrating ranks varying from zero to two for fourteen different panel dimensions. The usual specifications of deterministic components are considered. 相似文献
6.
ABSTRACT This paper reviews and extends the literature on the finite sample behavior of tests for sample selection bias. Monte Carlo results show that, when the “multicollinearity problem” identified by Nawata (1993) is severe, (i) the t-test based on the Heckman–Greene variance estimator can be unreliable, (ii) the Likelihood Ratio test remains powerful, and (iii) nonnormality can be interpreted as severe sample selection bias by Maximum Likelihood methods, leading to negative Wald statistics. We also confirm previous findings (Leung and Yu, 1996) that the standard regression-based t-test (Heckman, 1979) and the asymptotically efficient Lagrange Multiplier test (Melino, 1982), are robust to nonnormality but have very little power. 相似文献
7.
Extending the bifurcating autoregressive (BAR) process (cf. Cowan and Staudte, 1986) to multi-casting (multi-splitting) data, Hwang and Choi (2009) introduced multi-casting autoregression (MCAR, for short) defined on multi-casting tree structured data. This article is concerned with the case when the MCAR model is partially specified only through conditional mean and variance without directly imposing autoregressive (AR) structure. The resulting class of models will be referred to as P-MCAR (partially specified MCAR). The P-MCAR considerably enlarges the class of multi-casting models including (as special cases) MCAR, random coefficient MCAR, conditionally heteroscedastic multi-casting models and binomial-thinning processes. Moment structures for this broad P-MCAR class are investigated. Least squares (LS) estimation method is discussed and asymptotic relative efficiency (ARE) of the generalized-LS over ordinary-LS is obtained in a closed form. A simulation study is conducted to illustrate results. 相似文献
8.
In this article, we find designs insensitive to the presence of an outlier in a diallel cross design setup for estimating a complete set of orthonormal contrasts among the effects of the general combining abilities of a set of parental lines. The criterion of robustness, suggested by Mandal (1989) in block design setup and used by Biswas (2012) in treatment-control setup, is adapted here. Complete diallel cross designs, suggested by Gupta and Kageyama (1994), and partial diallel cross designs, suggested by Gupta et al. (1995) and Mukerjee (1997), are found to be robust under certain conditions. 相似文献
9.
《统计学通讯:理论与方法》2012,41(16-17):3043-3059
In molecular oncology the analysis of growth patterns of cells represent a major goal for understanding the evolution of growth profiles in pathological conditions. To compare various experimental settings in a pre-clinical study of inhibitors of prostate cancer, we modeled cancer cell growth using different statistical approaches which account for biological variability and complexity within experiments and over time. We first estimated cell growth by means of Linear Mixed Effects models that included unobserved factors that may influence cell development. Random effects were included to allow for no constant variance and covariance of residuals over time (Wu and West, 2009) and to properly model the whole growth process (i.e., all observation times). These are crucial aspects that are commonly ignored by the standard Linear Model. Since the nature of the data does not support the assumption of strictly linear effect of the continuous covariates on the predictor we present a solution within generalized additive models with mixed effects. An extension of this modeling to a fully Bayesian framework is also considered as it has a high degree of flexibility. 相似文献
10.
《统计学通讯:理论与方法》2012,41(16-17):3198-3210
The randomized response (RR) technique with two decks of cards proposed by Odumade and Singh (2009) can always be made more efficient than the RR techniques proposed by Warner (1965), Mangat and Singh (1990), and Mangat (1994) by adjusting the proportion of cards in the decks. The proposed method of Odumade and Singh (2009) is limited to simple random sampling with replacement (SRSWR) sampling only. In this article, generalization of Odumade and Singh strategy is provided for complex survey designs and a wider class of estimators. The results of Odumade and Singh (2009) can be derived from the proposed method as a special case. 相似文献
11.
Changli He 《Econometric Reviews》2013,32(1):34-59
This article considers tests for logistic smooth transition autoregressive (LSTAR) models accommodating multiple time dependent transitions between regimes when the data generating process is a random walk. The asymptotic null distributions of the tests, in contrast to the standard results in Lin and Teräsvirta (1994), are nonstandard. Monte Carlo experiments reveal that the tests have modest size distortions and satisfactory power against LSTAR models with multiple smooth breaks. The tests are applied to Swedish unemployment rates and the hysteresis hypothesis is over-turned in favour of an LSTAR model with two transitions between extreme regimes. 相似文献
12.
By applying the recursion of Huffer (1988) repeatedly, we propose an algorithm for evaluating the null joint distribution of Dixon-type test statistics for testing discordancy of k upper outliers in exponential samples. By using the critical values of Dixon-type test statistics determined from the proposed algorithm and those of Cochran-type test statistics presented earlier by Lin and Balakrishnan (2009), we carry out an extensive Monte Carlo study to investigate the powers and the error probabilities for the effects of masking and swamping when the number of outliers k = 2 and 3. Based on our empirical findings, we recommend Rosner’s (1975) sequential test procedure based on Dixon-type test statistics for testing multiple outliers from an exponential distribution. 相似文献
13.
In this article, we propose a nonparametric method to test for symmetry in bivariate data. By using the extension of Fisher's exact treatment for 2 × 2 contingency tables proposed by Freeman and Halton (1951), we can test the hypothesis of equal distribution for two samples of integer valued variables. Then, by counting the number of observations belonging to each cell of a symmetric, appropriately built grid, we can produce the two samples of integers required to use this test for equal distribution. The resulting test for symmetry is potentially extendible to higher dimensions. A simulation study is performed to compare with some known tests (Bowker, 1948; Hollander, 1971; and its improvement given in Krampe and Kuhnt, 2007). Our proposal represents a competitive option as a test for symmetry. 相似文献
14.
《统计学通讯:理论与方法》2013,42(11):2133-2145
ABSTRACT Stratification of distribution functions is an important issue in the area of income distributions. Two distribution functions form a perfect stratification if they occupy disjoint ranges on the horizontal axis. Otherwise, there is overlapping. A measure which quantifies the amount of stratification is introduced by Yitzhaki (1994), but no procedure for drawing inference is suggested. We develop a consistent estimator of the degree of overlapping and offer a nonparametric procedure for inference. Its limiting distribution, properly standardized, is normal. The asymptotic variance can be estimated using the jackknife method, and simulations show that the suggested procedure works well for sample sizes of 50 (100 for some cases). 相似文献
15.
The Significance Analysis of Microarrays (SAM; Tusher et al., 2001) method is widely used in analyzing gene expression data while controlling the FDR by using resampling-based procedure in the microarray setting. One of the main components of the SAM procedure is the adjustment of the test statistic. The introduction of the fudge factor to the test statistic aims at deflating the large value of test statistics due to the small standard error of gene-expression. Lin et al. (2008) pointed out that the fudge factor does not effectively improve the power and the control of the FDR as compared to the SAM procedure without the fudge factor in the presence of small variance genes. Motivated by the simulation results presented in Lin et al. (2008), in this article, we extend our study to compare several methods for choosing the fudge factor in the modified t-type test statistics and use simulation studies to investigate the power and the control of the FDR of the considered methods. 相似文献
16.
M. Revan Özkale 《统计学通讯:理论与方法》2013,42(7):1094-1097
In this note, we show that the estimator and the following results given by Zhong and Yang (2007) are the same with that of Groß (2003). 相似文献
17.
There have been many alternative strategies for implementing sampling survey on quantitative characteristic of sensitive issues by using randomized response (RR) technique. The efficiency of most of those strategies has been improved by choosing the suitable design parameters of model. However, the two different procedures with pre-assigned design parameter values cannot ensure that they possess the same protection degree to the respondents. Some earlier comparisons of those strategies are inadequate (as in Eichhorn and Hayre, 1983; Gupta et al., 2002). Some literature contains a more comprehensive comparison based on efficiency and protection degree to the respondents among the qualitative characteristic RR techniques (see Bhargava and Singh, 2002; Nayak, 1994; Zaizai and Zankan, 2004). As far as the comparisons are concerned that are based on efficiency and protection degree to the respondents among the quantitative characteristic RR techniques, very few related studies have been found so far. The purpose of this article is to give a more adequate comparison among those earlier quantitative characteristic RR strategies. It is found that several important differences between the results obtained in this article and some known results exist. Therefore, these earlier RR strategies should be reevaluated. 相似文献
18.
Feng-Shou Ko 《统计学通讯:理论与方法》2013,42(18):3222-3237
We introduce a score test to identify longitudinal biomarkers or surrogates for a time to event outcome. This method is an extension of Henderson et al. (2000, 2002). In this article, a score test is based on a joint likelihood function which combines the likelihood functions of the longitudinal biomarkers and the survival times. Henderson et al. (2000, 2002) assumed that the same random effect exists in the longitudinal component and in the Cox model and then they can derive a score test to determine if a longitudinal biomarker is associated with time to an event. We extend this work and our score test is based on a joint likelihood function which allows other random effects to be present in the survival function. Considering heterogeneous baseline hazards in individuals, we use simulations to explore how the factors can influence the power of a score test to detect the association of a longitudinal biomarker and the survival time. These factors include the functional form of the random effects from the longitudinal biomarkers, in the different number of individuals, and time points per individual. We illustrate our method using a prothrombin index as a predictor of survival in liver cirrhosis patients. 相似文献
19.
Huang (2010) proposed an optional randomized response model using a linear combination scrambling which is a generalization of the multiplicative scrambling of Eichhorn and Hayre (1983) and the additive scrambling of Gupta et al. (2006, 2010). In this article, we discuss two main issues. (1) Can the Huang (2010) model be improved further by using a two-stage approach?; (2) Does the linear combination scrambling provide any benefit over the additive scrambling of Gupta et al. (2010)? We will note that the answer to the first question is “yes” but the answer to the second question is “no.” 相似文献
20.
We propose a class of estimators for the population mean when there are missing data in the data set. Obtaining the mean square error equations of the proposed estimators, we show the conditions where the proposed estimators are more efficient than the sample mean, ratio-type estimators, and the estimators in Singh and Horn (2000) and Singh and Deo (2003) in the case of missing data. These conditions are also supported by a numerical example. 相似文献