On the estimation of the intraclass correlation

The problem of estimating the intraclass correlation when the sampling design is unbalanced is discussed. The method of moments is used to derive an approximation to the distribution of the estimate of the intraclass correlation obtained by the variance components approach. The maximum likelihood estimator is also presented, along with a simple procedure due to Richard (1961), for numerically maximizing a likelihood function of several parameters. Finally, the issue of optimal study design is considered for both balanced and unbalanced situations. For given power we determine the number of sets required to detect different values of the intraclass correlation.     

Bayes Estimation of Intraclass Correlation Coefficients Under Unequal Family Sizes

Bayesian inference for the intraclass correlation ρ is considered under unequal family sizes. We obtain the posterior distribution of ρ and then compare the performance of the Bayes estimator (posterior mean of ρ) with that of Srivastava's (1984) estimator through simulation. Simulation study shows that the Bayes estimator performs better than the Srivastava's estimator in terms of lower mean square error. We also obtain large sample posteriors of ρ based on the asymptotic posterior distribution and based on the Laplace approximation.     

Comparing Equal-Tail Probability and Unbiased Confidence Intervals for the Intraclass Correlation Coefficient

The conventional confidence interval for the intraclass correlation coefficient assumes equal-tail probabilities. In general, the equal-tail probability interval is biased and other interval procedures should be considered. Unbiased confidence intervals for the intraclass correlation coefficient are readily available. The equal-tail probability and unbiased intervals have exact coverage as they are constructed using the pivotal quantity method. In this article, confidence intervals for the intraclass correlation coefficient are built using balanced and unbalanced one-way random effects models. The expected length of confidence intervals serves as a tool to compare the two procedures. The unbiased confidence interval outperforms the equal-tail probability interval if the intraclass correlation coefficient is small and the equal-tail probability interval outperforms the unbiased interval if the intraclass correlation coefficient is large.     

Confidence intervals on the intraclass correlation in the unbalanced one-way classification

Several methods are compared for constructing confidence intervals on the intraclass correlation coefficient in the unbalanced one-way classification. The results suggest that a conservative approximation of the exact procedure developed by Wald (1940) can be used for hand calculations, When the exact solution is desired, a solution procedure is recommended that is computationally convenient and allows the investigator to determine the precision of the estimate. In cases where a prior estimate of the correlation is available, researchers may select intervals based on either the analysis of variance or unweighted sums of squares estimator.     

基于分层模型的缺失数据插补方法研究

大规模抽样调查多采用复杂抽样设计,得到具有分层嵌套结构的调查数据集,其中不可避免会遇到数据缺失问题,针对分层结构含缺失数据集的插补策略目前鲜有研究。本文将Gibbs算法应用到分层含缺失数据集的多重插补过程中,分别研究了固定效应模型插补法和随机效应模型插补法,进而通过理论推导和数值模拟,在不同组内相关系数、群组规模、数据缺失比例等情形下,从参数估计结果的无偏性和有效性两方面,比较不同方法的插补效果,给出插补模型的选择建议。研究结果表明,采用随机效应模型作为插补模型时,得到的参数估计结果更准确,而固定效应模型作为插补模型操作相对简便,在数据缺失比例较小、组内相关系数较大、群组规模较大等情形下,可以采用固定效应插补模型,否则建议采用随机效应插补模型。     

Profile Likelihood Based Confidence Intervals for Common Intraclass Correlation Coefficient

In this article, we propose an approach for estimating the confidence interval of the common intraclass correlation coefficient based on the profile likelihood. Comparisons are made with a procedure using the concept of generalized pivots. The method presented is less computationally demanding than the method using generalized pivots. The approach also provides better coverage, and shorter lengths of confidence intervals for the case when the value of the common intraclass correlation coefficient is low. The lengths of confidence intervals given by both methods are quite comparable for high but less realistic values of the common intraclass correlation coefficient.     

Notes on estimation of the intraclass correlation under the AB/BA crossover trial

Under the AB/BA crossover trial, we focus our attention on estimation of the intraclass correlation in normal data. We develop both point and interval estimators in closed form for the intraclass correlation. We employ Monte Carlo simulation to study the performance of these estimators in a variety of situations. We note that the estimators developed here for the intraclass correlation remain valid even when there are possibly unexpected carry-over effects.     

Estimating Intraclass Correlation Coefficient and Identifying Influential Observations Under One-Way Random Effects Model

In this paper we consider the estimation of intraclass correlation coefficient and identification of influential observations under one-way random effects model. We introduce an approach to correct negative estimation values induced by the method of moments estimator, and provide an interval estimation for intraclass correlation coefficient. We present the diagnostic tools to identify influential observations through the uncorrected estimate of intraclass correlation coefficient. A simulation study is conducted to investigate the performance of our procedure for identifying influential observations. We also apply the method on a real data of repeated blood pressure measurements.     

Generalized f variates in the general linear model

In this paper the theory of the generalized F variate is examined. A large class of statistics is constructed for linear for linear models when the errors are distributed N(0, ∑), where ∑ is positive definite. These statistics are shown to have a generalized F distribution. The role of the generalized F variate is then studied in detail for a linear model of constant intraclass correlation.     

Inferences on the intraclass correlation coefficients in the unbalanced two-way random effects model with interaction

In this paper, the hypothesis testing and interval estimation for the intraclass correlation coefficients are considered in a two-way random effects model with interaction. Two particular intraclass correlation coefficients are described in a reliability study. The tests and confidence intervals for the intraclass correlation coefficients are developed when the data are unbalanced. One approach is based on the generalized p-value and generalized confidence interval, the other is based on the modified large-sample idea. These two approaches simplify to the ones in Gilder et al. [2007. Confidence intervals on intraclass correlation coefficients in a balanced two-factor random design. J. Statist. Plann. Inference 137, 1199–1212] when the data are balanced. Furthermore, some statistical properties of the generalized confidence intervals are investigated. Finally, some simulation results to compare the performance of the modified large-sample approach with that of the generalized approach are reported. The simulation results indicate that the modified large-sample approach performs better than the generalized approach in the coverage probability and expected length of the confidence interval.     

Confidence interval estimation for a linear contrast in intraclass correlation coefficients under unequal family sizes for several populations

Confidence intervals [based on F-distribution and (Z) standard normal distribution] for a linear contrast in intraclass correlation coefficients under unequal family sizes for several populations based on several independent multinormal samples have been proposed. It has been found that the confidence interval based on F-distribution consistently and reliably produced better results in terms of shorter average length of the interval than the confidence interval based on standard normal distribution for various combinations of intraclass correlation coefficient values. The coverage probability of the interval based on F-distribution is competitive with the coverage probability of the interval based on standard normal distribution. The interval based on F-distribution can be used for both small sample and large sample situations. An example with real life data has been presented.     

Estimation of Several Intraclass Correlation Coefficients

An intraclass correlation coefficient observed in several populations is estimated. The basis is a variance-stabilizing transformation. It is shown that the intraclass correlation coefficient from any elliptical distribution should be transformed in the same way. Four estimators are compared. An estimator where the components in a vector consisting of the transformed intraclass correlation coefficients are estimated separately, an estimator based on a weighted average of these components, a pretest estimator where the equality of the components is tested and then the outcome of the test is used in the estimation procedure, and a James-Stein estimator which shrinks toward the mean.     

An error-bounded polynomial approximation for bivariate normal probabilities

Although the bivariate normal distribution is frequently employed in the development of screening models, the formulae for computing bivariate normal probabilities are quite complicated. A simple and accurate error-bounded, noniterative approximation for bivariate normal probabilities based on a simple univariate normal quadratic or cubic approximation is developed for use in screening applications. The approximation, which is most accurate for large absolute correlation coefficients, is especially suitable for screening applications (e.g., in quality control), where large absolute correlations between performance and screening variables are desired. A special approximation for conditional bivariate normal probabilities is also provided which in quality control screening applications improves the accuracy of estimating the average outgoing product quality. Some anomalies in computing conditional bivariate normal probabilities using BNRDF and NORDF in IMSL are also discussed.     

Maximum likeihood estimation of an intraclass correlation in a bivariate normal distribution with missing observations

The maximum likeihood estimate is considered for an intraclass correlation coefficent in a bivariate normal distribution when some observations on either of the varibles are missuing. The estimate is given as the soulution of a polynomial equation of degree seven. An approximate confidence interval and a test procedure for the intraclass correlation are constricted based on an asymptotic variance stabilizing transformation of the resulting estimator. The distributional results are also considered under violation of the normality assumption. A Monte Carlo study was performed to examine the finite sample properties of the maximum likelihood estimator and to evaluate the proposed procedures for hypotheses testing and interval estimation.     

Second-order properties of intraclass correlation estimators for a symmetric normal distribution

Consider the problem of estimating the intraclass correlation coefficient of a symmetric normal distribution under the squared error loss function. The general admissibility of the standard estimators of the intraclass correlation coefficient is hard to check due to their complicated sampling distributions. We follow the asymptotic decision-theoretic approach of Ghosh and Sinha (1981) and prove that the three standard intraclass correlation estimators (the maximum-likelihood estimator, the method-of-moments estimator and the first-order unbiased estimator) are second-order admissible for all p ≥ 2, p being the dimension of the distribution.     

An approximation to the distribution of the product of two dependent correlation coefficients

Many methodological studies depend on the product of two dependent correlation coefficients. However, the behavior of the distribution of the product of two dependent correlation coefficients is not well known. The distribution of sets of correlation coefficients has been well studied, but not the distribution of the product of two dependent correlation coefficients. The present study derives an approximation to the distribution of the product of two dependent correlation coefficients with a closed form, resulting in a Pearson Type I distribution. A simulation study is also conducted to assess the accuracy of the approximation.     

A Comparison of Significance Testing Procedures for the Intraclass Correlation from Family Data

Different procedures for testing problems concerning intraclass correlation from familial data are considered in the case of varying number of siblings per family. Under the assumption of multivariate normality, the hypotheses that the intraclass correlation is equal to a specified value are tested. To assess the performance of the tests, Monte Carlo simulations are designed to compare their powers. The Neyman's (1959) C(α) test and the test based on the modified ANOVA F statistic are shown to be consistently more powerful than other procedures.     

Test for the equality of interclass correlation cofefficients under unequal family sizes for several populations

Large sample ANOVA test and likelihood ratio test have been Proposed to test for the equaiity of sevcrai iniraciass correlation coefiicients unier unequai family sizes based on several independent multinormal samples, it has been found on the basis of simulation study that the likelihood ratio test consistenily and reliably produced results superior to those of the large sample ANOVA test in terms of power for various combinations of intraclass correlatxon coefficient values.     

Bayesian estimation of log odds ratios over two-way contingency tables with intraclass correlated cells

In this article, a Bayesian approach is proposed for the estimation of log odds ratios and intraclass correlations over a two-way contingency table, including intraclass correlated cells. Required likelihood functions of log odds ratios are obtained, and determination of prior structures is discussed. Hypothesis testing for log odds ratios and intraclass correlations by using the posterior simulations is outlined. Because the proposed approach includes no asymptotic theory, it is useful for the estimation and hypothesis testing of log odds ratios in the presence of certain intraclass correlation patterns. A family health status and limitations data set is analyzed by using the proposed approach in order to figure out the impact of intraclass correlations on the estimates and hypothesis tests of log odds ratios. Although intraclass correlations are small in the data set, we obtain that even small intraclass correlations can significantly affect the estimates and test results, and our approach is useful for the estimation and testing of log odds ratios in the presence of intraclass correlations.     

Estimation of the Intraclass Correlation Coefficient for the Analysis of Covariance Model

For the unbalanced analysis of covariance model with one covariate, a simple formula is given for the intraclass correlation coefficient estimator that results from Henderson's Method 3 estimation of variance components. Example calculations and the corresponding interpretations are given for a study of the correlation of iron content among brothers. The example illustrates the manner in which the estimator depends on the pattern of correlation between the covariate and the variable under investigation.