Hypothesis Testing in Functional Comparative Calibration Models

The purpose of this article is to investigate hypothesis testing in functional comparative calibration models. Wald type statistics are considered which are asymptotically distributed according to the chi-square distribution. The statistics are based on maximum likelihood, corrected score approach, and method of moment estimators of the model parameters, which are shown to be consistent and asymptotically normally distributed. Results of analytical and simulation studies seem to indicate that the Wald statistics based on the method of moment estimators and the corrected score estimators are, as expected, less efficient than the Wald type statistic based on the maximum likelihood estimators for small n. Wald statistic based on moment estimators are simpler to compute than the other Wald statistics tests and their performance improves significantly as n increases. Comparisons with an alternative F statistics proposed in the literature are also reported.     

Rényi statistics for testing composite hypotheses in general exponential models

We introduce a family of Rényi statistics of orders r?∈?R for testing composite hypotheses in general exponential models, as alternatives to the previously considered generalized likelihood ratio (GLR) statistic and generalized Wald statistic. If appropriately normalized exponential models converge in a specific sense when the sample size (observation window) tends to infinity, and if the hypothesis is regular, then these statistics are shown to be χ²-distributed under the hypothesis. The corresponding Rényi tests are shown to be consistent. The exact sizes and powers of asymptotically α-size Rényi, GLR and generalized Wald tests are evaluated for a concrete hypothesis about a bivariate Lévy process and moderate observation windows. In this concrete situation the exact sizes of the Rényi test of the order r?=?2 practically coincide with those of the GLR and generalized Wald tests but the exact powers of the Rényi test are on average somewhat better.     

On the wald,lagrangian multiplier and likelihood ratio tests when the information matrix is singular

Summary Modified formulas for the Wald and Lagrangian multiplier statistics are introduced and considered together with the likelihood ratio statistics for testing a typical null hypothesisH ₀ stated in terms of equality constraints. It is demonstrated, subject to known standard regularity conditions, that each of these statistics and the known Wald statistic has the asymptotic chi-square distribution with degrees of freedom equal to the number of equality constraints specified byH ₀ whether the information matrix is singular or nonsingular. The results of this paper include a generalization of the results of Sively (1959) concerning the equivalence of the Wald, Lagrange multiplier and likelihood ratio tests to the case of singular information matrices.     

ROBUST ESTIMATION AND HYPOTHESIS TESTS FOR FIRST-ORDER THRESHOLD AUTOREGRESSIVE MODELS

Results of Petrucelli & Woolford (1984) for a first-order threshold autoregressive model are considered from a robust point of view. Robust estimators of the threshold parameters of the model are obtained and their asymptotic normality is proved. Testing the equality of the threshold parameters is considered using the robust analogues of Wald and score test statistics. Limiting distributions of these statistics are given under both null and alternative hypotheses.     

Testing for multivariate heteroscedasticity

In this article, we propose a testing technique for multivariate heteroscedasticity, which is expressed as a test of linear restrictions in a multivariate regression model. Four test statistics with known asymptotical null distributions are suggested, namely the Wald, Lagrange multiplier (LM), likelihood ratio (LR) and the multivariate Rao F-test. The critical values for the statistics are determined by their asymptotic null distributions, but bootstrapped critical values are also used. The size, power and robustness of the tests are examined in a Monte Carlo experiment. Our main finding is that all the tests limit their nominal sizes asymptotically, but some of them have superior small sample properties. These are the F, LM and bootstrapped versions of Wald and LR tests.     

Hypothesis Testing of Hazard Ratio Parameters in Marginal Models for Multivariate Failure Time Data

Marginal hazard models for multivariate failure time data have been studied extensively in recent literature. However, standard hypothesis test statistics based on the likelihood method are not exactly appropriate for this kind of model. In this paper, extensions of the three commonly used likelihood hypothesis test statistics are discussed. Generalized Wald, generalized score and generalized likelihood ratio tests for hazard ratio parameters in a marginal hazard model for multivariate failure time data are proposed and their asymptotic distributions examined. The finite sample properties of these statistics are studied through simulations. The proposed method is applied to data from Busselton Population Health Surveys.     

Which Wald statistic? Choosing a parameterization of the Wald statistic to maximize power in k-sample generalized estimating equations

The Wald statistic is known to vary under reparameterization. This raises the question: which parameterization should be chosen, in order to optimize power of the Wald statistic? We specifically consider k-sample tests of generalized linear models (GLMs) and generalized estimating equations (GEEs) in which the alternative hypothesis contains only two parameters. An example is presented in which such an alternative hypothesis is of interest. Amongst a general class of parameterizations, we find the parameterization that maximizes power via analysis of the non-centrality parameter, and show how the effect on power of reparameterization depends on sampling design and the differences in variance across samples. There is no single parameterization with optimal power across all alternatives. The Wald statistic commonly used under the canonical parameterization is optimal in some instances but it performs very poorly in others. We demonstrate results by example and by simulation, and describe their implications for likelihood ratio statistics and score statistics. We conclude that due to poor power properties, the routine use of score statistics and Wald statistics under the canonical parameterization for GEEs is a questionable practice.     

Robust Small Sample Inference for Generalised Estimating Equations: An Application of the Anova‐type Test

Asymptotically, the Wald‐type test for generalised estimating equations (GEE) models can control the type I error rate at the nominal level. However in small sample studies, it may lead to inflated type I error rates. Even with currently available small sample corrections for the GEE Wald‐type test, the type I error rate inflation is still serious when the tested contrast is multidimensional. This paper extends the ANOVA‐type test for heteroscedastic factorial designs to GEE and shows that the proposed ANOVA‐type test can also control the type I error rate at the nominal level in small sample studies while still maintaining robustness with respect to mis‐specification of the working correlation matrix. Differences of inference between the Wald‐type test and the proposed test are observed in a two‐way repeated measures ANOVA model for a diet‐induced obesity study and a two‐way repeated measures logistic regression for a collagen‐induced arthritis study. Simulation studies confirm that the proposed test has better control of the type I error rate than the Wald‐type test in small sample repeated measures models. Additional simulation studies further show that the proposed test can even achieve larger power than the Wald‐type test in some cases of the large sample repeated measures ANOVA models that were investigated.     

Inference from PseudoLikelihoods with Plug‐In Estimates

Effective implementation of likelihood inference in models for high‐dimensional data often requires a simplified treatment of nuisance parameters, with these having to be replaced by handy estimates. In addition, the likelihood function may have been simplified by means of a partial specification of the model, as is the case when composite likelihood is used. In such circumstances tests and confidence regions for the parameter of interest may be constructed using Wald type and score type statistics, defined so as to account for nuisance parameter estimation or partial specification of the likelihood. In this paper a general analytical expression for the required asymptotic covariance matrices is derived, and suggestions for obtaining Monte Carlo approximations are presented. The same matrices are involved in a rescaling adjustment of the log likelihood ratio type statistic that we propose. This adjustment restores the usual chi‐squared asymptotic distribution, which is generally invalid after the simplifications considered. The practical implication is that, for a wide variety of likelihoods and nuisance parameter estimates, confidence regions for the parameters of interest are readily computable from the rescaled log likelihood ratio type statistic as well as from the Wald type and score type statistics. Two examples, a measurement error model with full likelihood and a spatial correlation model with pairwise likelihood, illustrate and compare the procedures. Wald type and score type statistics may give rise to confidence regions with unsatisfactory shape in small and moderate samples. In addition to having satisfactory shape, regions based on the rescaled log likelihood ratio type statistic show empirical coverage in reasonable agreement with nominal confidence levels.     

Inference for a skew extension of the Grubbs model

In this paper, we discuss inferential aspects for the Grubbs model when the unknown quantity x (latent response) follows a skew-normal distribution, extending early results given in Arellano-Valle et al. (J Multivar Anal 96:265–281, 2005b). Maximum likelihood parameter estimates are computed via the EM-algorithm. Wald and likelihood ratio type statistics are used for hypothesis testing and we explain the apparent failure of the Wald statistics in detecting skewness via the profile likelihood function. The results and methods developed in this paper are illustrated with a numerical example.     

Design-based analysis of embedded experiments with applications in the Dutch Labour Force Survey

Summary.  Previous research has proposed a design-based analysis procedure for experiments that are embedded in complex sampling designs in which the ultimate sampling units of an on-going sample survey are randomized over different treatments according to completely randomized designs or randomized block designs. Design-based Wald and t -statistics are applied to test whether sample means that are observed under various survey implementations are significantly different. This approach is generalized to experimental designs in which clusters of sampling units are randomized over the different treatments. Furthermore, test statistics are derived to test differences between ratios of two sample estimates that are observed under alternative survey implementations. The methods are illustrated with a simulation study and real life applications of experiments that are embedded in the Dutch Labour Force Survey. The functionality of a software package that was developed to conduct these analyses is described.     

Parametric bootstrap and approximate tests for two Poisson variates

The parametric bootstrap tests and the asymptotic or approximate tests for detecting difference of two Poisson means are compared. The test statistics used are the Wald statistics with and without log-transformation, the Cox F statistic and the likelihood ratio statistic. It is found that the type I error rate of an asymptotic/approximate test may deviate too much from the nominal significance level α under some situations. It is recommended that we should use the parametric bootstrap tests, under which the four test statistics are similarly powerful and their type I error rates are all close to α. We apply the tests to breast cancer data and injurious motor vehicle crash data.     

Empirical Study of Six Tests for Equality of Populations with Zero-Inflated Continuous Distributions

We evaluated the properties of six statistical methods for testing equality among populations with zero-inflated continuous distributions. These tests are based on likelihood ratio (LR), Wald, central limit theorem (CLT), modified CLT (MCLT), parametric jackknife (PJ), and nonparametric jackknife (NPJ) statistics. We investigated their statistical properties using simulated data from mixed distributions with an unknown portion of non zero observations that have an underlying gamma, exponential, or log-normal density function and the remaining portion that are excessive zeros. The 6 statistical tests are compared in terms of their empirical Type I errors and powers estimated through 10,000 repeated simulated samples for carefully selected configurations of parameters. The LR, Wald, and PJ tests are preferred tests since their empirical Type I errors were close to the preset nominal 0.05 level and each demonstrated good power for rejecting null hypotheses when the sample sizes are at least 125 in each group. The NPJ test had unacceptable empirical Type I errors because it rejected far too often while the CLT and MCLT tests had low testing powers in some cases. Therefore, these three tests are not recommended for general use but the LR, Wald, and PJ tests all performed well in large sample applications.     

Likelihood Ratio Tests for Fixed Model Terms using Residual Maximum Likelihood

Likelihood ratio tests for fixed model terms are proposed for the analysis of linear mixed models when using residual maximum likelihood estimation. Bartlett-type adjustments, using an approximate decomposition of the data, are developed for the test statistics. A simulation study is used to compare properties of the test statistics proposed, with or without adjustment, with a Wald test. A proposed test statistic constructed by dropping fixed terms from the full fixed model is shown to give a better approximation to the asymptotic χ²-distribution than the Wald test for small data sets. Bartlett adjustment is shown to improve the χ²-approximation for the proposed tests substantially.     

Likelihood-based tests in zero-inflated power series models

We address the issue of performing testing inference in the class of zero-inflated power series models. These models provide a straightforward way of modelling count data and have been widely used in practical situations. The likelihood ratio, Wald and score statistics provide the basis for testing the parameter of inflation of zeros in this class of models. In this paper, in addition to the well-known test statistics, we also consider the recently proposed gradient statistic. We conduct Monte Carlo simulation experiments to evaluate the finite-sample performance of these tests for testing the parameter of inflation of zeros. The numerical results show that the new gradient test we propose is more reliable in finite samples than the usual likelihood ratio, Wald and score tests. An empirical application to real data is considered for illustrative purposes.     

Testing linearity against nonlinear moving average models

Lagrange multiplier (LM) test statistics are derived for testing a linear moving average model against an asymmetric moving average model and an LM type test against an additive smooth transition moving average model. The latter model is introduced in the paper. The small sample performance of the proposed tests are evaluated in a Monte Carlo study and compared to Wald and likelihood ratio statistics. The size properties of the Lagrange multiplier test are better than those of other tests.     

Some asymptotic results for hypothesis testing in multivariate failure time data

This paper presents a class of generalized Wald, generalized score and generalized likelihood ratio statistics for hypothesis testing and model selection for multivariate failure time data. These statistics are based on a marginal hazard model with a common baseline hazard function. The large sample distributions of these statistics are examined. It is shown that the proposed test statistics follow asymptotically a weighted sum of independent χ₁² distributions.     

Testing overdispersion in the zero-inflated Poisson model

The zero-inflated negative binomial (ZINB) model is used to account for commonly occurring overdispersion detected in data that are initially analyzed under the zero-inflated Poisson (ZIP) model. Tests for overdispersion (Wald test, likelihood ratio test [LRT], and score test) based on ZINB model for use in ZIP regression models have been developed. Due to similarity to the ZINB model, we consider the zero-inflated generalized Poisson (ZIGP) model as an alternate model for overdispersed zero-inflated count data. The score test has an advantage over the LRT and the Wald test in that the score test only requires that the parameter of interest be estimated under the null hypothesis. This paper proposes score tests for overdispersion based on the ZIGP model and illustrates that the derived score statistics are exactly the same as the score statistics under the ZINB model. A simulation study indicates the proposed score statistics are preferred to other tests for higher empirical power. In practice, based on the approximate mean–variance relationship in the data, the ZINB or ZIGP model can be considered, and a formal score test based on asymptotic standard normal distribution can be employed for assessing overdispersion in the ZIP model. We provide an example to illustrate the procedures for data analysis.     

Asymptotic relative efficiency of wald tests in measurement error models

In this paper, asymptotic relative efficiency (ARE) of Wald tests for the Tweedie class of models with log-linear mean, is considered when the aux¬iliary variable is measured with error. Wald test statistics based on the naive maximum likelihood estimator and on a consistent estimator which is obtained by using Nakarnura's (1990) corrected score function approach are defined. As shown analytically, the Wald statistics based on the naive and corrected score function estimators are asymptotically equivalents in terms of ARE. On the other hand, the asymptotic relative efficiency of the naive and corrected Wald statistic with respect to the Wald statistic based on the true covariate equals to the square of the correlation between the unobserved and the observed co-variate. A small scale numerical Monte Carlo study and an example illustrate the small sample size situation.