Bayesian least squares estimates of univariate regression functions

The regression function R(?) to be estimated is assumed to have an expansion in terms of specified functions, orthogonalized vich respect to values of the explanatory variable. Relative precisions of OBSERVATION are assumed known. The estimate is the posterior linear mean of R(?) given the data. The investigator plots graphs of appropriate functions as an aid in eliciting his prior means and precisions for the coefficients in the expansion. The method is illustrated by an example using simulated data, an example in which effects of various dosages of Vitamin D are estimated, and an example in which a utility function is estimated.     

An asymptotic theory for semiparametric generalized least squares estimation in partially linear regression models

Consider a partially linear regression model with an unknown vector parameter β, an unknown functiong(·), and unknown heteroscedastic error variances. In this paper we develop an asymptotic semiparametric generalized least squares estimation theory under some weak moment conditions. These moment conditions are satisfied by many of the error distributions encountered in practice, and our theory does not require the number of replications to go to infinity.     

Quantile regression via iterative least squares computations

We present an estimating framework for quantile regression where the usual L ₁-norm objective function is replaced by its smooth parametric approximation. An exact path-following algorithm is derived, leading to the well-known ‘basic’ solutions interpolating exactly a number of observations equal to the number of parameters being estimated. We discuss briefly possible practical implications of the proposed approach, such as early stopping for large data sets, confidence intervals, and additional topics for future research.     

Partial least squares Cox regression for genome-wide data

Most methods for survival prediction from high-dimensional genomic data combine the Cox proportional hazards model with some technique of dimension reduction, such as partial least squares regression (PLS). Applying PLS to the Cox model is not entirely straightforward, and multiple approaches have been proposed. The method of Park et al. (Bioinformatics 18(Suppl. 1):S120–S127, 2002) uses a reformulation of the Cox likelihood to a Poisson type likelihood, thereby enabling estimation by iteratively reweighted partial least squares for generalized linear models. We propose a modification of the method of park et al. (2002) such that estimates of the baseline hazard and the gene effects are obtained in separate steps. The resulting method has several advantages over the method of park et al. (2002) and other existing Cox PLS approaches, as it allows for estimation of survival probabilities for new patients, enables a less memory-demanding estimation procedure, and allows for incorporation of lower-dimensional non-genomic variables like disease grade and tumor thickness. We also propose to combine our Cox PLS method with an initial gene selection step in which genes are ordered by their Cox score and only the highest-ranking k% of the genes are retained, obtaining a so-called supervised partial least squares regression method. In simulations, both the unsupervised and the supervised version outperform other Cox PLS methods.     

Second-order least squares estimation of censored regression models

This paper proposes the second-order least squares estimation, which is an extension of the ordinary least squares method, for censored regression models where the error term has a general parametric distribution (not necessarily normal). The strong consistency and asymptotic normality of the estimator are derived under fairly general regularity conditions. We also propose a computationally simpler estimator which is consistent and asymptotically normal under the same regularity conditions. Finite sample behavior of the proposed estimators under both correctly and misspecified models are investigated through Monte Carlo simulations. The simulation results show that the proposed estimator using optimal weighting matrix performs very similar to the maximum likelihood estimator, and the estimator with the identity weight is more robust against the misspecification.     

The peculiar shrinkage properties of partial least squares regression

Partial least squares regression has been widely adopted within some areas as a useful alternative to ordinary least squares regression in the manner of other shrinkage methods such as principal components regression and ridge regression. In this paper we examine the nature of this shrinkage and demonstrate that partial least squares regression exhibits some undesirable properties.     

On finite-sample properties of adaptive least squares regression estimates

This paper is mainly concerned with deriving finite-sample properties of least squares estimators for the regression function in a nonparametric regression situation under some simplifying assumptions such as normally distributed errors with a common known variance. The selection of basis functions to be used for the construction of an estimator may be regarded as a smoothing problem, and will usually be done in a data-dependent way, A straightforward application of a result by P. J. Kernpthorne yields that, under a squared error loss, all selection procedures are admissible. Furthermore, the minimax approach provides an interpolating estimator, which is often impractical, Therefore, within a certain class of selection procedures an optimal one is determined using the minimax regret principle. It can be seen to behave similarly to the procedure minimizing either an unbiased risk estimator or, equivalently, the C_p-criterion.     

Study of partial least squares and ridge regression methods

This article considers both Partial Least Squares (PLS) and Ridge Regression (RR) methods to combat multicollinearity problem. A simulation study has been conducted to compare their performances with respect to Ordinary Least Squares (OLS). With varying degrees of multicollinearity, it is found that both, PLS and RR, estimators produce significant reductions in the Mean Square Error (MSE) and Prediction Mean Square Error (PMSE) over OLS. However, from the simulation study it is evident that the RR performs better when the error variance is large and the PLS estimator achieves its best results when the model includes more variables. However, the advantage of the ridge regression method over PLS is that it can provide the 95% confidence interval for the regression coefficients while PLS cannot.     

A new approach to statistical efficiency of weighted least squares fitting algorithms for reparameterization of nonlinear regression models

We study nonlinear least-squares problem that can be transformed to linear problem by change of variables. We derive a general formula for the statistically optimal weights and prove that the resulting linear regression gives an optimal estimate (which satisfies an analogue of the Rao-Cramer lower bound) in the limit of small noise.     

Bayes least squares linear estimation of densities

Linear, least squares statistical methods in which the "parameters" are interpreted as random variables were introduced by Whittle, and further developed by Hartigan and others. They are applied here to the problem of estimating the coefficients in an orthogonal expansion of a multivariate density, given a simple random sample.     

Efficiency of least squares estimators in the presence of spatial autocorrelation

The effect of spatial autocorrelation on inferences made using ordinary least squares estimation is considered. It is found, in some cases, that ordinary least squares estimators provide a reasonable alternative to the estimated generalized least squares estimators recommended in the spatial statistics literature. One of the most serious problems in using ordinary least squares is that the usual variance estimators are severely biased when the errors are correlated. An alternative variance estimator that adjusts for any observed correlation is proposed. The need to take autocorrelation into account in variance estimation negates much of the advantage that ordinary least squares estimation has in terms of computational simplicity     

Fitting linear regression models to censored data by least squares and maximum likelihood methods

Several approaches have been suggested for fitting linear regression models to censored data. These include Cox's propor­tional hazard models based on quasi-likelihoods. Methods of fitting based on least squares and maximum likelihoods have also been proposed. The methods proposed so far all require special purpose optimization routines. We describe an approach here which requires only a modified standard least squares routine.

We present methods for fitting a linear regression model to censored data by least squares and method of maximum likelihood. In the least squares method, the censored values are replaced by their expectations, and the residual sum of squares is minimized. Several variants are suggested in the ways in which the expect­ation is calculated. A parametric (assuming a normal error model) and two non-parametric approaches are described. We also present a method for solving the maximum likelihood equations in the estimation of the regression parameters in the censored regression situation. It is shown that the solutions can be obtained by a recursive algorithm which needs only a least squares routine for optimization. The suggested procesures gain considerably in computational officiency. The Stanford Heart Transplant data is used to illustrate the various methods.     

An empirical investigation of the box-cox model and a nonlinear least squares alternative

In this paper we present a generalized functional form estimator, recently developed by jeffrey Wooldridge; and then we compare it empirically to the popular Box-Cox (BC) estimator using three data sets. We begin by briefly reviewing the drawbacks of the BC estimator. We Then introduce the nonlinear lest squares (NLS) alternative of Wooldridge which retains the desirable qualities of the BC estimator without the associated theoretical problems. We continue by applying both the BC and the NLS models to data from three classic hedonic regression studies and then compare the estimation resuts-point estimates, inferences and fitted values. The estimations include a wage rate equation, and two computer hedonic regression equations, one using data from a classic study by Gregory Chow and the other using an IBM data set that formed the basis of the new official BLS computer price index.     

An empirical investigation of the box-cox model and a nonlinear least squares alternative

In this paper we present a generalized functional form estimator, recently developed by jeffrey Wooldridge; and then we compare it empirically to the popular Box-Cox (BC) estimator using three data sets. We begin by briefly reviewing the drawbacks of the BC estimator. We Then introduce the nonlinear lest squares (NLS) alternative of Wooldridge which retains the desirable qualities of the BC estimator without the associated theoretical problems. We continue by applying both the BC and the NLS models to data from three classic hedonic regression studies and then compare the estimation resuts-point estimates, inferences and fitted values. The estimations include a wage rate equation, and two computer hedonic regression equations, one using data from a classic study by Gregory Chow and the other using an IBM data set that formed the basis of the new official BLS computer price index.     

A simulation study on SPSS ridge regression and ordinary least squares regression procedures for multicollinearity data

This study compares the SPSS ordinary least squares (OLS) regression and ridge regression procedures in dealing with multicollinearity data. The LS regression method is one of the most frequently applied statistical procedures in application. It is well documented that the LS method is extremely unreliable in parameter estimation while the independent variables are dependent (multicollinearity problem). The Ridge Regression procedure deals with the multicollinearity problem by introducing a small bias in the parameter estimation. The application of Ridge Regression involves the selection of a bias parameter and it is not clear if it works better in applications. This study uses a Monte Carlo method to compare the results of OLS procedure with the Ridge Regression procedure in SPSS.     

Multivariate boundary kernels and a continuous least squares principle

Whereas there are many references on univariate boundary kernels, the construction of boundary kernels for multivariate density and curve estimation has not been investigated in detail. The use of multivariate boundary kernels ensures global consistency of multivariate kernel estimates as measured by the integrated mean-squared error or sup-norm deviation for functions with compact support. We develop a class of boundary kernels which work for any support, regardless of the complexity of its boundary. Our construction yields a boundary kernel for each point in the boundary region where the function is to be estimated. These boundary kernels provide a natural continuation of non-negative kernels used in the interior onto the boundary. They are obtained as solutions of the same kernel-generating variational problem which also produces the kernel function used in the interior as its solution. We discuss the numerical implementation of the proposed boundary kernels and their relationship to locally weighted least squares. Along the way we establish a continuous least squares principle and a continuous analogue of the Gauss–Markov theorem.     

Computing least trimmed squares regression with the forward search

Least trimmed squares (LTS) provides a parametric family of high breakdown estimators in regression with better asymptotic properties than least median of squares (LMS) estimators. We adapt the forward search algorithm of Atkinson (1994) to LTS and provide methods for determining the amount of data to be trimmed. We examine the efficiency of different trimming proportions by simulation and demonstrate the increasing efficiency of parameter estimation as larger proportions of data are fitted using the LTS criterion. Some standard data examples are analysed. One shows that LTS provides more stable solutions than LMS.     

Generalized least squares with misspecified serial correlation structures

Summary. The regression literature contains hundreds of studies on serially correlated disturbances. Most of these studies assume that the structure of the error covariance matrix Ω is known or can be estimated consistently from data. Surprisingly, few studies investigate the properties of estimated generalized least squares (GLS) procedures when the structure of Ω is incorrectly identified and the parameters are inefficiently estimated. We compare the finite sample efficiencies of ordinary least squares (OLS), GLS and incorrect GLS (IGLS) estimators. We also prove new theorems establishing theoretical efficiency bounds for IGLS relative to GLS and OLS. Results from an exhaustive simulation study are used to evaluate the finite sample performance and to demonstrate the robustness of IGLS estimates vis-à-vis OLS and GLS estimates constructed for models with known and estimated (but correctly identified) Ω. Some of our conclusions for finite samples differ from established asymptotic results.