Controlled Direct and Mediated Effects: Definition,Identification and Bounds

Abstract. Results are given which provide bounds for controlled direct effects when nounmeasured confounding assumptions required for the identification of these effects do not hold. Previous results concerning bounds for controlled direct effects rely on monotonicity relationships between the treatment, mediator and the outcome themselves; the results presented in this article instead assume that monotonicity relationships hold between the unmeasured confounding variable or variables and the treatment, mediator and outcome. Whereas prior results give bounds that contain the null hypothesis of no direct effect, the results presented here will in many instances yield bounds that do not contain the null hypothesis of no direct effect. For contexts in which a set of variables intercepts all paths between a treatment and an outcome, it is possible to provide a definition for a controlled mediated effect. We discuss the identification of these controlled mediated effects; the bounds for controlled direct effects are applicable also to controlled mediated effects. An example is given to illustrate how the results in the article can be used to draw inferences about direct and mediated effects in the presence of unmeasured confounding variables.     

Direct and Indirect Effects Based on Difference-in-Differences With an Application to Political Preferences Following the Vietnam Draft Lottery

Abstract

We propose a difference-in-differences approach for disentangling a total treatment effect within specific subpopulations into a direct effect and an indirect effect operating through a binary mediating variable. Random treatment assignment along with specific common trend and effect homogeneity assumptions identify the direct effects on the always and never takers, whose mediator is not affected by the treatment, as well as the direct and indirect effects on the compliers, whose mediator reacts to the treatment. In our empirical application, we analyze the impact of the Vietnam draft lottery on political preferences. The results suggest that a high draft risk due to the draft lottery outcome leads to an increase in mild preferences for the Republican Party, but has no effect on strong preferences for either party or on specific political attitudes. The increase in Republican support is mostly driven by the direct effect not operating through the mediator that is military service.     

Path analysis and determining the distribution of indirect effects via simulation

The difference between a path analysis and the other multivariate analyses is that the path analysis has the ability to compute the indirect effects apart from the direct effects. The aim of this study is to investigate the distribution of indirect effects that is one of the components of path analysis via generated data. To realize this, a simulation study has been conducted with four different sample sizes, three different numbers of explanatory variables and with three different correlation matrices. A replication of 1000 has been applied for every single combination. According to the results obtained, it is found that irrespective of the sample size path coefficients tend to be stable. Moreover, path coefficients are not affected by correlation types either. Since the replication number is 1000, which is fairly large, the indirect effects from the path models have been treated as normal and their confidence intervals have been presented as well. It is also found that the path analysis should not be used with three explanatory variables. We think that this study would help scientists who are working in both natural and social sciences to determine sample size and different number of variables in the path analysis.     

Variable selection in joint location and scale models of the skew-normal distribution

A regression model with skew-normal errors provides a useful extension for ordinary normal regression models when the data set under consideration involves asymmetric outcomes. Variable selection is an important issue in all regression analyses, and in this paper, we investigate the simultaneously variable selection in joint location and scale models of the skew-normal distribution. We propose a unified penalized likelihood method which can simultaneously select significant variables in the location and scale models. Furthermore, the proposed variable selection method can simultaneously perform parameter estimation and variable selection in the location and scale models. With appropriate selection of the tuning parameters, we establish the consistency and the oracle property of the regularized estimators. Simulation studies and a real example are used to illustrate the proposed methodologies.     

OFDI对中国国际收支影响的机理与实际测算

国际直接投资不仅会影响东道国国际收支,也会对投资母国国际收支产生影响。本文重点分析了对外直接投资对母国国际收支的影响机制,并构建了对外直接投资对母国国际收支影响的数理分析框架,研究表明对外直接投资通过投资效应、利润汇回效应和贸易效应所包含的七个渠道影响母国国际收支;对外直接投资初期会造成母国国际收支净效应为负的情形,但伴随对外直接投资存量的累积,国际收支净效应会逐步为正。最后本文测算了中国对外直接投资对其国际收支的影响,结果表明中国对外直接投资收益率大于国内投资收益率;近年来国际收支净效应持续为负,但对改善 “双顺差”模式起到了积极作用。     

Formative Indicators and Effects of a Causal Model for Household Human Capital with Application

Dagum and Slottje (2000) estimated household human capital (HC) as a latent variable (LV) and proposed its monetary estimation by means of an actuarial approach. This paper introduces an improved method for the estimation of household HC as an LV by means of formative and reflective indicators in agreement with the accepted economic definition of HC. The monetary value of HC is used in a recursive causal model to obtain short- and long-term multipliers that measure the direct and total effects of the variables that determine household HC. The new method is applied to estimate US household HC for year 2004.     

Formative Indicators and Effects of a Causal Model for Household Human Capital with Application

Dagum and Slottje (2000 Dagum , C. , Slottje , D. J. ( 2000 ). A new method to estimate the level and distribution of the household human capital with applications . Journal of Structural Change and Economic Dynamics 11 : 67 – 94 .[Crossref] , [Google Scholar]) estimated household human capital (HC) as a latent variable (LV) and proposed its monetary estimation by means of an actuarial approach. This paper introduces an improved method for the estimation of household HC as an LV by means of formative and reflective indicators in agreement with the accepted economic definition of HC. The monetary value of HC is used in a recursive causal model to obtain short- and long-term multipliers that measure the direct and total effects of the variables that determine household HC. The new method is applied to estimate US household HC for year 2004.     

Identification of Local Causal Effects with Missing Outcome Values and an Instrument for Non Response

Even in randomized experiments the identification of causal effects is often threatened by the presence of missing outcome values, with missingness possibly being non ignorable. We provide sufficient conditions under which the availability of a binary instrument for non response allows us to non parametrically point identify average causal effects in some latent subgroups of units, named Principal Strata, defined by their non response behavior in all possible combinations of treatment and instrument. Examples are provided as possible scenarios where our assumptions may be plausible.     

The Use of Working Variables in the Bayesian Modeling of Mean and Dispersion Parameters in Generalized Nonlinear Models with Random Effects

This article is aimed at reviewing a novel Bayesian approach to handle inference and estimation in the class of generalized nonlinear models. These models include some of the main techniques of statistical methodology, namely generalized linear models and parametric nonlinear regression. In addition, this proposal extends to methods for the systematic treatment of variation that is not explicitly predicted within the model, through the inclusion of random effects, and takes into account the modeling of dispersion parameters in the class of two-parameter exponential family. The methodology is based on the implementation of a two-stage algorithm that induces a hybrid approach based on numerical methods for approximating the likelihood to a normal density using a Taylor linearization around the values of current parameters in an MCMC routine.     

A monte carlo study of variable selection and inferences in a two stage random coefficient linear regression model with unbalanced data

A growth curve analysis is often applied to estimate patterns of changes in a given characteristic of different individuals. It is also used to find out if the variations in the growth rates among individuals are due to effects of certain covariates. In this paper, a random coefficient linear regression model, as a special case of the growth curve analysis, is generalized to accommodate the situation where the set of influential covariates is not known a priori. Two different approaches for seleaing influential covariates (a weighted stepwise selection procedure and a modified version of Rao and Wu’s selection criterion) for the random slope coefficient of a linear regression model with unbalanced data are proposed. Performances of these methods are evaluated by means of Monte-Carlo simulation. In addition, several methods (Maximum Likelihood, Restricted Maximum Likelihood, Pseudo Maximum Likelihood and Method of Moments) for estimating the parameters of the selected model are compared Proposed variable selection schemes and estimators are appliedtotheactualindustrial problem which motivated this investigation.     

陕西油气资源开发与区域经济增长的关联效应分析

研究油气资源开发与陕西区域经济增长的关联效应,对陕西油气资源合理开发利用以及陕西区域经济增长具有重要的参考价值。利用陕西省2007年投入产出表,对陕西油气资源行业的投入效应、产出效应、产业关联效应以及收入分配效应进行了实证分析,结果显示油气资源开发行业特别是下游的石油化工行业具有较高的产业关联效应,能较好地促进区域经济增长。     

The Analysis of Methadone Clinic Data Using Marginal and Conditional Logistic Models with Mixture or Random Effects

The paper develops methods for the statistical analysis of outcomes of methadone maintenance treatment (MMT). Subjects for this study were a cohort of patients entering MMT in Sydney in 1986. Urine drug tests on these subjects were performed weekly during MMT, and were reported as either positive or negative for morphine, the marker of recent heroin use. To allow correlation between the repeated binary measurements, a marginal logistic model was fitted using the generalized estimating equation (GEE) approach and the alternating logistic regression approach. Conditional logistic models are also considered. Results of separate fitting to each patient and score tests suggest that there is substantial between-patient variation in response to MMT. To account for the population heterogeneity and to facilitate subject-specific inference, the conditional logistic model is extended by introducing random intercepts. The two, three and four group mixture models are also investigated. The model of best fit is a three group mixture model, in which about a quarter of the subjects have a poor response to MMT, with continued heroin use independent of daily dose of methadone; about a quarter of the subjects have a very good response, with little or no heroin use, again independent of dose; and about half the subjects responded in a dose-dependent fashion, with reduced heroin use while receiving higher doses of methadone. These findings are consistent with clinical experience. There is also an association between reduced drug use and increased duration in treatment. The mixture model is recommended since it is quite tractable in terms of estimation and model selection as well as being supported by clinical experience.     

中国区域食品价格差异收敛性检验——基于微观价格数据的空间计量与动态效应分析

构建有别于以往文献的区域价格β收敛空间计量分析框架,实证研究了1994年以来中国食品价格差异收敛性及其动态变化特征。研究发现:1994年以来,中国食品价格收敛速度表现出了先减弱后增强的U型动态变化特征,而非此前文献所揭示的逐步增强,这是由改革红利的"螺旋效应"所致,且最近几年中国食品价格收敛性在走弱,应引起特别注意。对此,进一步的分析表明,主要原因可能包括三期叠加的宏观经济形势、有所抬头的新型贸易壁垒、食品消费结构升级以及国内宾大效应。     

Stochastic volatility in mean models with scale mixtures of normal distributions and correlated errors: A Bayesian approach

A stochastic volatility in mean model with correlated errors using the symmetrical class of scale mixtures of normal distributions is introduced in this article. The scale mixture of normal distributions is an attractive class of symmetric distributions that includes the normal, Student-t, slash and contaminated normal distributions as special cases, providing a robust alternative to estimation in stochastic volatility in mean models in the absence of normality. Using a Bayesian paradigm, an efficient method based on Markov chain Monte Carlo (MCMC) is developed for parameter estimation. The methods developed are applied to analyze daily stock return data from the São Paulo Stock, Mercantile & Futures Exchange index (IBOVESPA). The Bayesian predictive information criteria (BPIC) and the logarithm of the marginal likelihood are used as model selection criteria. The results reveal that the stochastic volatility in mean model with correlated errors and slash distribution provides a significant improvement in model fit for the IBOVESPA data over the usual normal model.