首页 | 本学科首页   官方微博 | 高级检索  
相似文献
 共查询到20条相似文献,搜索用时 46 毫秒
1.
Decisionmakers need information about the anticipated future costs of maintaining polio eradication as a function of the policy options under consideration. Given the large portfolio of options, we reviewed and synthesized the existing cost data relevant to current policies to provide context for future policies. We model the expected future costs of different strategies for continued vaccination, surveillance, and other costs that require significant potential resource commitments. We estimate the costs of different potential policy portfolios for low-, middle-, and high-income countries to demonstrate the variability in these costs. We estimate that a global transition from routine immunization with oral poliovirus vaccine (OPV) to inactivated poliovirus vaccine (IPV) would increase the costs of managing polio globally, although routine IPV use remains less costly than routine OPV use with supplemental immunization activities. The costs of surveillance and a stockpile, while small compared to routine vaccination costs, represent important expenditures to ensure adequate response to potential outbreaks. The uncertainty and sensitivity analyses highlight important uncertainty in the aggregated costs and demonstrates that the discount rate and uncertainty in price and administration cost of IPV drives the expected incremental cost of routine IPV vs. OPV immunization.  相似文献   

2.
考虑多种安全设置策略的物流网络的选址-库存问题,不仅是选址、订货、运输和库存的集成优化,还需要考虑多种不同的安全库存设置和转运策略。因此,本文深入讨论了二级物流网络中的六种安全库存设置策略,构建了六种考虑不同安全库存设置的选址-库存模型。在考虑集中设置安全库存时,集中安全库存需要通过转载运输实现,因此需要将转载运输成本引入选址-库存模型之中,使新的选址-库存模型更加科学合理。另外,针对六种新的选址-库存模型,提出了基于个体成本差异分配的遗传算法,迭代搜索选址、分配、库存设置策略的优化组合。最后,通过数据实验验证了模型的有效性:(1)安全库存与转载运输之间存在此消彼长的背反关系;(2)安全库存设置和转载运输策略对总成本的影响取决于两种费率权重情况。本文的研究可以为二级物流网络的选址、订货和安全库存策略集成优化决策提供参考依据。  相似文献   

3.
Cranes are a key element in construction projects as they are the primary lifting equipment and among the most expensive construction equipment. Thus, crane selection and location are important factors for a construction project’s operational and economic success. In this research, we focus on a site with supply and demand areas that have to be connected by tower cranes. There are several tower crane models differing in certain specifications such as costs or operating radius. The objective is to select cranes and determine their locations so that each demand area is connected to its supply area at minimum cost. We detail the problem setting and show how to obtain a discrete set of candidate locations for each crane model without losing optimality. This discretization allows us to reduce our problem to the classic set cover problem. Despite its NP-hardness, instances of considerable size can be solved to optimality within reasonable computing time using a standard solver. In an extensive computational study, we analyze the performance of the proposed approach in terms of solution quality, computation times, and drivers of computational effort.  相似文献   

4.
Flight retiming in airline scheduling consists in slightly modifying the scheduled departure time of some flights with the goal of providing a better service with a cheaper cost. In this research, the departure times must be selected from a small discrete set of options. The whole problem embeds flight retiming, fleet assignment, aircraft routing and crew pairing. Thus, the aim is to determine the departure times of the flights, the fleet assignment and the minimum cost aircraft and crew routes. The objective function takes into account a large cost associated with each crew member, a penalization for short or long connection times, a cost for crew members changing aircraft along their routes, and a minor penalty associated with the use of each aircraft. The constraints enforce aircraft maintenance and crew working rules. In this setting, flight retiming is allowed to potentially reduce the total costs and increase the robustness of the solution against delays by decreasing the number of aircraft changes.We propose and compare four heuristic algorithms based on a Mixed Integer Linear Programming model for the whole problem. The model contains path variables representing the crew pairings, and arc variables representing the aircraft routes. In the heuristic algorithms, column generation is applied on the path variables, and different flight retiming options are considered. The algorithms are tested on real-world instances of a regional carrier flying in the Canary Islands to evaluate their advantages and drawbacks. In particular, one of the algorithms, that uses the solution of the Linear Programming relaxation of the model to select promising options for the departure of the flights, turns out to be the most effective one. The obtained results show that costs can be significantly reduced through flight retiming while still keeping the computing times reasonably short. In addition, we perform a sensitivity analysis by including more retiming options and by using different aircraft and crew costs. Finally, we report the results on larger size instances obtained by combining real-world ones.  相似文献   

5.
After an intentional release of chlorine in an office district, public responses such as sheltering‐in‐place could save many lives if rapid enough. However, previous work does not estimate how fast and effective such responses would be for several possible investments in attack detection, public alert, and building ventilation, nor whether such measures would be cost effective. We estimate public response times with investment options in place, and resulting changes in fatalities as well as system costs, including false alarm costs, and cost effectiveness in terms of cost per net death avoided. The measures do have life‐saving potential, especially if all response times are at or near the lower limits of the ranges assumed in this article. However, due to uncertainties, it is not clear that responses would be rapid enough to save many people. In some cases total fatalities would increase, since sheltering after chlorine vapor has already entered buildings can increase occupants’ chlorine exposure. None of the options considered have median cost per statistical life saved meeting a cost‐effectiveness threshold of $6.5 million across all of the chlorine exposure dose‐response and ingress‐delay models considered here, even if there were one attack per year in the area covered by the system. Given these and other issues discussed in this article, at this point investments to improve sheltering‐in‐place capability appear not to be robust strategies for reducing fatalities from chlorine attack in an office district.  相似文献   

6.
We analyze the benefit of production/service capacity sharing for a set of independent firms. Firms have the choice of either operating their own production/service facilities or investing in a facility that is shared. Facilities are modeled as queueing systems with finite service rates. Firms decide on capacity levels (the service rate) to minimize delay costs and capacity investment costs possibly subject to service‐level constraints on delay. If firms decide to operate a shared facility they must also decide on a scheme for sharing the capacity cost. We formulate the problem as a cooperative game and identify settings under which capacity sharing is beneficial and there is a cost allocation that is in the core under either the first‐come, first‐served policy or an optimal priority policy. We show that capacity sharing may not be beneficial in settings where firms have heterogeneous work contents and service variabilities. In such cases, we specify conditions under which capacity sharing may still be beneficial for a subset of the firms.  相似文献   

7.
Operations management methods have been applied profitably to a wide range of technology portfolio management problems, but have been slow to be adopted by governments and policy makers. We develop a framework that allows us to apply such techniques to a large and important public policy problem: energy technology R&D portfolio management under climate change. We apply a multi‐model approach, implementing probabilistic data derived from expert elicitations into a novel stochastic programming version of a dynamic integrated assessment model. We note that while the unifying framework we present can be applied to a range of models and data sets, the specific results depend on the data and assumptions used and therefore may not be generalizable. Nevertheless, the results are suggestive, and we find that the optimal technology portfolio for the set of projects considered is fairly robust to different specifications of climate uncertainty, to different policy environments, and to assumptions about the opportunity cost of investing. We also conclude that policy makers would do better to over‐invest in R&D rather than under‐invest. Finally, we show that R&D can play different roles in different types of policy environments, sometimes leading primarily to cost reduction, other times leading to better environmental outcomes.  相似文献   

8.
This study analyzes optimal replenishment policies that minimize expected discounted cost of multi‐product stochastic inventory systems. The distinguishing feature of the multi‐product inventory system that we analyze is the existence of correlated demand and joint‐replenishment costs across multiple products. Our objective is to understand the structure of the optimal policy and use this structure to construct a heuristic method that can solve problems set in real‐world sizes/dimensions. Using an MDP formulation we first compute the optimal policy. The optimal policy can only be computed for problems with a small number of product types due to the curse of dimensionality. Hence, using the insight gained from the optimal policy, we propose a class of policies that captures the impact of demand correlation on the structure of the optimal policy. We call this class (scdS)‐policies, and also develop an algorithm to compute good policies in this class, for large multi‐product problems. Finally using an exhaustive set of computational examples we show that policies in this class very closely approximate the optimal policy and can outperform policies analyzed in prior literature which assume independent demand. We have also included examples that illustrate performance under the average cost objective.  相似文献   

9.
《Omega》1986,14(3):239-244
Recent technological developments have brought on a revolution in the design and operation of warehousing systems. Automatic storage/retrieval systems (AS/RS) driven by embedded computers are becoming increasingly more prevalent. The increased use of AS/RS is creating the need for computerized control algorithms to support the scheduling and logistical decisions in such automated warehouses. In this research we explore the problem of deciding which storage locations to retrieve when confronted with a set of discrete orders for a given inventory item. In addition to the normal costs associated with the retrieval decision, this support introduces the cost of a location “breakdown” as a complicating factor in the retrieval decision. The problem is formulated as a type of mixed zero-one integer program. Computational results from a sample set of problems are reported.  相似文献   

10.
We consider a continuous review inventory system where delivery lead times can be managed by expediting in‐transit orders shipped from the supplier. First, we propose an ordering/expediting policy and derive expressions for evaluating the operating characteristics of such systems. Second, using extensive numerical experiments, we quantify the benefits of such an expediting policy. Third, we investigate a number of managerial issues. Specifically, we analyze the impact of the number of expediting hubs and their locations along the shipment network on the performance of such systems and offer insights into the design of the shipment network. We show (i) a single expediting hub that is optimally located in a shipment network can capture the majority of cost savings achieved by a multi‐hub system, especially when expediting cost is not low or demand variability is not high; (ii) when expediting time is proportional to the time to destination, for small‐enough or large‐enough demand variations, a single expediting hub located in the middle of the shipment network can capture the majority of cost savings of an optimally located hub; and (iii) in general, hubs close to the retailer significantly drive down costs, whereas hubs close to the supplier may not offer much cost savings.  相似文献   

11.
Non-stationary stochastic demands are very common in industrial settings with seasonal patterns, trends, business cycles, and limited-life items. In such cases, the optimal inventory control policies are also non-stationary. However, due to high computational complexity, non-stationary inventory policies are not usually preferred in real-life applications. In this paper, we investigate the cost of using a stationary policy as an approximation to the optimal non-stationary one. Our numerical study points to two important results: (i) Using stationary policies can be very expensive depending on the magnitude of demand variability. (ii) Stationary policies may be efficient approximations to optimal non-stationary policies when demand information contains high uncertainty, setup costs are high and penalty costs are low.  相似文献   

12.
基于Stackelberg博弈的变质物品分销网络设计模型   总被引:2,自引:1,他引:2  
黄松  杨超  杨珺 《中国管理科学》2009,17(6):122-129
研究了一类短销售期的变质物品的分销网络设计问题.假定零售商的缺货成本依赖于分配给为其提供服务的分销中心的库存成本,供应商在销售期末给零售商提供第二次订货机会,供应商根据零售商的订货决策确定分销中心的最优选址和确定每个分销中心为哪些零售商提供服务,从而最小化总的运作成本(选址成本,运输成本,库存成本和变质成本),其中分销中心的运输成本和库存成本依赖于零售商确定的订货数量;而零售商则根据供应商的决策确定自身的最优订货决策,利用Stackelberg博弈分析的方法,建立了一类变质物品的分销网络设计模型,并使用拉格朗日松弛算法求解,最后通过数值算例分析了模型最优解对于参数的敏感性.  相似文献   

13.
Feature costing is a topic of recent discussion related to cost management systems (CMSs) aimed at understanding how product features influence production process costs. It raises as a key issue in mass customisation environments where a single product model can present hundreds of menu options. In this study, we explore the concept of feature costing beyond the use of activity-based costing (ABC). We propose a CMS based on features and common elements as costing objects instead of products. In our model, we use the unit of production effort method to organise the direct manufacturing costs, ABC method to address the indirect cost and the standard methods to compute raw materials costs. We illustrate the method in the production of bus seats in a Brazilian manufacturing company. This study gives different perspectives to the international academic community on the use of a different CMS used by many Brazilian companies.  相似文献   

14.
Through observations from real life hub networks, we introduce the multimodal hub location and hub network design problem. We approach the hub location problem from a network design perspective. In addition to the location and allocation decisions, we also study the decision on how the hub networks with different possible transportation modes must be designed. In this multimodal hub location and hub network design problem, we jointly consider transportation costs and travel times, which are studied separately in most hub location problems presented in the literature. We allow different transportation modes between hubs and different types of service time promises between origin–destination pairs while designing the hub network in the multimodal problem. We first propose a linear mixed integer programming model for this problem and then derive variants of the problem that might arise in certain applications. The models are enhanced via a set of effective valid inequalities and an efficient heuristic is developed. Computational analyses are presented on the various instances from the Turkish network and CAB data set.  相似文献   

15.
Ula? Özen  Mustafa K. Do?ru 《Omega》2012,40(3):348-357
We consider a single-stage inventory system facing non-stationary stochastic demand of the customers in a finite planning horizon. Motivated by the practice, the replenishment times need to be determined and frozen once and for all at the beginning of the horizon while decisions on the exact replenishment quantities can be deferred until the replenishment time. This operating scheme is refereed to as a “static-dynamic uncertainty” strategy in the literature [3]. We consider dynamic fixed-ordering and linear end-of-period holding costs, as well as dynamic penalty costs, or service levels. We prove that the optimal ordering policy is a base stock policy for both penalty cost and service level constrained models. Since an exponential exhaustive search based on dynamic programming yields the optimal ordering periods and the associated base stock levels, it is not possible to compute the optimal policy parameters for longer planning horizons. Thus, we develop two heuristics. Numerical experiments show that both heuristics perform well in terms of solution quality and scale-up efficiently; hence, any practically relevant large instance can be solved in reasonable time. Finally, we discuss how our results and heuristics can be extended to handle capacity limitations and minimum order quantity considerations.  相似文献   

16.
John M. Gleason 《Omega》1975,3(5):605-608
This paper considers the problem of locating bus stops in the context of a set covering problem. Zero-one integer programming models are suggested for use in the location of bus stops on new routes and for use in the location of express bus stops on current routes. The models may be used to locate the minimum number of (express) bus stops required to ensure that no passenger need walk more than a specified distance to reach an (express) bus stop. A modified version of the model is presented which enables the router to locate a specified number of (express) bus stops in such a manner that the total distance walked by all boarders is minimized.  相似文献   

17.
海外仓作为一带一路战略环境下的一种新型跨境物流模式,具有运输时间短、退换货快等特点。本文在跨境电商的背景下,综合考虑建仓成本、运输费用、运输时间和税费等因素,提出了海外仓选址多目标优化模型,随后基于分层序列法设计了二分搜索-最小费用流算法对该模型进行求解,并证明该算法在多项式时间内可以得到最优解,最后通过算例证实了该模型和算法的有效性和实用性,这为跨境电商海外仓选址提供了理论依据和决策支持。  相似文献   

18.
在项目投资面临运营滞后以及债务融资约束的情形下,基于实物期权框架构建了企业家签订信用担保互换契约的两阶段投资决策模型。运用动态规划以及均衡定价方法,给出了企业家股权及期权价值的显示表达,得到了两个阶段担保成本满足的代数方程,并进一步分析了运营滞后和信用担保下企业家的最优投资决策问题。数值结果表明:外部运营时滞会提高杠杆率,导致企业家提前投资,同时会提高企业家第一阶段债务融资的担保成本,但会降低第二阶段债务融资的担保成本;随第一阶段投资额度逐渐增大,企业家的最优投资水平呈U型变化,第一阶段债务融资时的担保成本单调递减,而第二段债务融资时的担保成本呈现倒U型;企业家两个阶段的融资缺口对项目最优投资水平、最优破产水平以及担保成本有显著影响。  相似文献   

19.
Deliberations are underway to utilize increasingly radical technological options to help address climate change and stabilize the climatic system. Collectively, these options are often referred to as “climate geoengineering.” Deployment of such options, however, can create wicked tradeoffs in governance and require adaptive forms of risk management. In this study, we utilize a large and novel set of qualitative expert interview data to more deeply and systematically explore the types of risk–risk tradeoffs that may emerge from the use of 20 different climate geoengineering options, 10 that focus on carbon dioxide or greenhouse gas removal, and 10 that focus on solar radiation management and reflecting sunlight. We specifically consider: What risks does the deployment of these options entail? What types of tradeoffs may emerge through their deployment? We apply a framework that clusters risk–risk tradeoffs into institutional and governance, technological and environmental, and behavioral and temporal dimensions. In doing so, we offer a more complete inventory of risk–risk tradeoffs than those currently available within the respective risk-assessment, energy-systems, and climate-change literatures, and we also point the way toward future research gaps concerning policy, deployment, and risk management.  相似文献   

20.
In this paper, we aim to design a monetary policy for the euro area that is robust to the high degree of model uncertainty at the start of monetary union and allows for learning about model probabilities. To this end, we compare and ultimately combine Bayesian and worst‐case analysis using four reference models estimated with pre–European Monetary Union (EMU) synthetic data. We start by computing the cost of insurance against model uncertainty, that is, the relative performance of worst‐case or minimax policy versus Bayesian policy. While maximum insurance comes at moderate costs, we highlight three shortcomings of this worst‐case insurance policy: (i) prior beliefs that would rationalize it from a Bayesian perspective indicate that such insurance is strongly oriented towards the model with highest baseline losses; (ii) the minimax policy is not as tolerant towards small perturbations of policy parameters as the Bayesian policy; and (iii) the minimax policy offers no avenue for incorporating posterior model probabilities derived from data available since monetary union. Thus, we propose preferences for robust policy design that reflect a mixture of the Bayesian and minimax approaches. We show how the incoming EMU data may then be used to update model probabilities, and investigate the implications for policy. (JEL: E52, E58, E61)  相似文献   

设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号