An empirical investigation of the box-cox model and a nonlinear least squares alternative

In this paper we present a generalized functional form estimator, recently developed by jeffrey Wooldridge; and then we compare it empirically to the popular Box-Cox (BC) estimator using three data sets. We begin by briefly reviewing the drawbacks of the BC estimator. We Then introduce the nonlinear lest squares (NLS) alternative of Wooldridge which retains the desirable qualities of the BC estimator without the associated theoretical problems. We continue by applying both the BC and the NLS models to data from three classic hedonic regression studies and then compare the estimation resuts-point estimates, inferences and fitted values. The estimations include a wage rate equation, and two computer hedonic regression equations, one using data from a classic study by Gregory Chow and the other using an IBM data set that formed the basis of the new official BLS computer price index.     

An Iterative Weighted Least Squares Algorithm and Simulation Study for Censored Data M-Estimates

A popular linear regression estimator for censored data is the one proposed by Buckley and James (1979). However, this estimator is not robust to outliers, which is not surprising since it is a modified version of the uncensored data least squares estimator. Lai and Ying (1994) have proposed an M-estimator for censored data that is a generalization of the Buckley- James estimator. In this paper we discuss a weighted least squares algorithm for computing these M-estimates and compare the performance of two Huber M-estimators with the Buckley-James estimator in a simulation study. We find that the Huber M-estimators perform more robustly for a broad range of censoring and error distributions.     

Regression model for surrogate data in high dimensional statistics

Abstract

This paper deals with the problem of estimating the regression of a surrogated scalar response variable given a functional random one. We construct an estimator of the regression operator by using, in addition to the available (true) response data, a surrogate data. We then establish some asymptotic properties of the constructed estimator in terms of the almost-complete and the quadratic mean convergences. Notice that the obtained results generalize a part of the results obtained in the finite dimensional framework. Finally, an illustration on the applicability of our results on both simulated data and a real dataset was realized. We have thus shown the superiority of our estimator on classical estimators when we are lacking complete data.     

Logistic regression in meta-analysis using aggregate data

We derived two methods to estimate the logistic regression coefficients in a meta-analysis when only the 'aggregate' data (mean values) from each study are available. The estimators we proposed are the discriminant function estimator and the reverse Taylor series approximation. These two methods of estimation gave similar estimators using an example of individual data. However, when aggregate data were used, the discriminant function estimators were quite different from the other two estimators. A simulation study was then performed to evaluate the performance of these two estimators as well as the estimator obtained from the model that simply uses the aggregate data in a logistic regression model. The simulation study showed that all three estimators are biased. The bias increases as the variance of the covariate increases. The distribution type of the covariates also affects the bias. In general, the estimator from the logistic regression using the aggregate data has less bias and better coverage probabilities than the other two estimators. We concluded that analysts should be cautious in using aggregate data to estimate the parameters of the logistic regression model for the underlying individual data.     

Empirical Uncertain Bayes Methods in Area‐level Models

Random effects model can account for the lack of fitting a regression model and increase precision of estimating area‐level means. However, in case that the synthetic mean provides accurate estimates, the prior distribution may inflate an estimation error. Thus, it is desirable to consider the uncertain prior distribution, which is expressed as the mixture of a one‐point distribution and a proper prior distribution. In this paper, we develop an empirical Bayes approach for estimating area‐level means, using the uncertain prior distribution in the context of a natural exponential family, which we call the empirical uncertain Bayes (EUB) method. The regression model considered in this paper includes the Poisson‐gamma and the binomial‐beta, and the normal‐normal (Fay–Herriot) model, which are typically used in small area estimation. We obtain the estimators of hyperparameters based on the marginal likelihood by using a well‐known expectation‐maximization algorithm and propose the EUB estimators of area means. For risk evaluation of the EUB estimator, we derive a second‐order unbiased estimator of a conditional mean squared error by using some techniques of numerical calculation. Through simulation studies and real data applications, we evaluate a performance of the EUB estimator and compare it with the usual empirical Bayes estimator.     

Assessing the Precision of Turning Point Estimates in Polynomial Regression Functions

Researchers often report point estimates of turning point(s) obtained in polynomial regression models but rarely assess the precision of these estimates. We discuss three methods to assess the precision of such turning point estimates. The first is the delta method that leads to a normal approximation of the distribution of the turning point estimator. The second method uses the exact distribution of the turning point estimator of quadratic regression functions. The third method relies on Markov chain Monte Carlo methods to provide a finite sample approximation of the exact distribution of the turning point estimator. We argue that the delta method may lead to misleading inference and that the other two methods are more reliable. We compare the three methods using two data sets from the environmental Kuznets curve literature, where the presence and location of a turning point in the income-pollution relationship is the focus of much empirical work.     

Trimmed likelihood estimators for lifetime experiments and their influence functions

We study the behaviour of trimmed likelihood estimators (TLEs) for lifetime models with exponential or lognormal distributions possessing a linear or nonlinear link function. In particular, we investigate the difference between two possible definitions for the TLE, one called original trimmed likelihood estimator (OTLE) and one called modified trimmed likelihood estimator (MTLE) which is the finite sample version of a form for location and linear regression used by Bednarski and Clarke [Trimmed likelihood estimation of location and scale of the normal distribution. Aust J Statist. 1993;35:141–153, Asymptotics for an adaptive trimmed likelihood location estimator. Statistics. 2002;36:1–8] and Bednarski et al. [Adaptive trimmed likelihood estimation in regression. Discuss Math Probab Stat. 2010;30:203–219]. The OTLE is always an MTLE but the MTLE may not be unique even in cases where the OLTE is unique. We compare especially the functional forms of both types of estimators, characterize the difference with the implicit function theorem and indicate situations where they coincide and where they do not coincide. Since the functional form of the MTLE has a simpler form, we use it then for deriving the influence function, again with the help of the implicit function theorem. The derivation of the influence function for the functional form of the OTLE is similar but more complicated.     

Assessing the Precision of Turning Point Estimates in Polynomial Regression Functions

Researchers often report point estimates of turning point(s) obtained in polynomial regression models but rarely assess the precision of these estimates. We discuss three methods to assess the precision of such turning point estimates. The first is the delta method that leads to a normal approximation of the distribution of the turning point estimator. The second method uses the exact distribution of the turning point estimator of quadratic regression functions. The third method relies on Markov chain Monte Carlo methods to provide a finite sample approximation of the exact distribution of the turning point estimator. We argue that the delta method may lead to misleading inference and that the other two methods are more reliable. We compare the three methods using two data sets from the environmental Kuznets curve literature, where the presence and location of a turning point in the income-pollution relationship is the focus of much empirical work.     

Bayesian quantile regression for parametric nonlinear mixed effects models

We propose quantile regression (QR) in the Bayesian framework for a class of nonlinear mixed effects models with a known, parametric model form for longitudinal data. Estimation of the regression quantiles is based on a likelihood-based approach using the asymmetric Laplace density. Posterior computations are carried out via Gibbs sampling and the adaptive rejection Metropolis algorithm. To assess the performance of the Bayesian QR estimator, we compare it with the mean regression estimator using real and simulated data. Results show that the Bayesian QR estimator provides a fuller examination of the shape of the conditional distribution of the response variable. Our approach is proposed for parametric nonlinear mixed effects models, and therefore may not be generalized to models without a given model form.     

Adaptive composite quantile regressions and their asymptotic relative efficiency

The composite quantile regression (CQR for short) provides an efficient and robust estimation for regression coefficients. In this paper we introduce two adaptive CQR methods. We make two contributions to the quantile regression literature. The first is that, both adaptive estimators treat the quantile levels as realizations of a random variable. This is quite different from the classic CQR in which the quantile levels are typically equally spaced, or generally, are treated as fixed values. Because the asymptotic variances of the adaptive estimators depend upon the generic distribution of the quantile levels, it has the potential to enhance estimation efficiency of the classic CQR. We compare the asymptotic variance of the estimator obtained by the CQR with that obtained by quantile regressions at each single quantile level. The second contribution is that, in terms of relative efficiency, the two adaptive estimators can be asymptotically equivalent to the CQR method as long as we choose the generic distribution of the quantile levels properly. This observation is useful in that it allows to perform parallel distributed computing when the computational complexity issue arises for the CQR method. We compare the relative efficiency of the adaptive methods with respect to some existing approaches through comprehensive simulations and an application to a real-world problem.     

Automated selection of post‐strata using a model‐assisted regression tree estimator

Despite having desirable properties, model‐assisted estimators are rarely used in anything but their simplest form to produce official statistics. This is due to the fact that the more complicated models are often ill suited to the available auxiliary data. Under a model‐assisted framework, we propose a regression tree estimator for a finite‐population total. Regression tree models are adept at handling the type of auxiliary data usually available in the sampling frame and provide a model that is easy to explain and justify. The estimator can be viewed as a post‐stratification estimator where the post‐strata are automatically selected by the recursive partitioning algorithm of the regression tree. We establish consistency of the regression tree estimator and a variance estimator, along with asymptotic normality of the regression tree estimator. We compare the performance of our estimator to other survey estimators using the United States Bureau of Labor Statistics Occupational Employment Statistics Survey data.     

Estimation of proportion ratio in non-compliance randomized trials with repeated measurements in binary data

It is not uncommon to encounter a randomized clinical trial (RCT) in which each patient is treated with several courses of therapies and his/her response is taken after treatment with each course because of the nature of a treatment design for a disease. On the basis of a simple multiplicative risk model proposed elsewhere for repeated binary measurements, we derive the maximum likelihood estimator (MLE) for the proportion ratio (PR) of responses between two treatments in closed form without the need of modeling the complicated relationship between patient’s compliance and patient’s response. We further derive the asymptotic variance of the MLE and propose an asymptotic interval estimator for the PR using the logarithmic transformation. We also consider two other asymptotic interval estimators. One is derived from the principle of Fieller’s Theorem and the other is derived by using the randomization-based approach suggested elsewhere. To evaluate and compare the finite-sample performance of these interval estimators, we apply the Monte Carlo simulation. We find that the interval estimator using the logarithmic transformation of the MLE consistently outperforms the other two estimators with respect to efficiency. This gain in efficiency can be substantial especially when there are patients not complying with their assigned treatments. Finally, we employ the data regarding the trial of using macrophage colony stimulating factor (M-CSF) over three courses of intensive chemotherapies to reduce febrile neutropenia incidence for acute myeloid leukemia patients to illustrate the use of these estimators.     

Robust Regression Using Data Partitioning and M-Estimation

We propose a new robust regression estimator using data partition technique and M estimation (DPM). The data partition technique is designed to define a small fixed number of subsets of the partitioned data set and to produce corresponding ordinary least square (OLS) fits in each subset, contrary to the resampling technique of existing robust estimators such as the least trimmed squares estimator. The proposed estimator shares a common strategy with the median ball algorithm estimator that is obtained from the OLS trial fits only on a fixed number of subsets of the data. We examine performance of the DPM estimator in the eleven challenging data sets and simulation studies. We also compare the DPM with the five commonly used robust estimators using empirical convergence rates relative to the OLS for clean data, robustness through mean squared error and bias, masking and swamping probabilities, the ability of detecting the known outliers, and the regression and affine equivariances.     

Visualization and Bandwidth Matrix Choice

In this study we compare three estimators of the extreme value index: Pickands estimator, the moment estimator and a maximum likelihood estimator. The estimators are explored both theoretically and by Monte Carlo simulation. We obtain two estimators for large quantiles using Pickands and the maximum likelihood estimators. The latter and one based on the moment estimator are then compared through simulation.     

Estimation under Cox proportional hazards model with covariates missing not at random

This paper considers likelihood-based estimation under the Cox proportional hazards model in the situations where some covariate entries are missing not at random. Assuming the conditional distribution of the missing entries is known, we demonstrate the existence of the semiparametric maximum likelihood estimator of the model parameters, establish the consistency and weak convergence. By simulation, we examine the finite-sample performance of the estimation procedure, and compare the SPMLE with the one resulted from using an estimated conditional distribution of the missing entries. We analyze the data from a tuberculosis (TB) study applying the proposed approach for illustration.     

Boundary and Bias Correction in Kernel Hazard Estimation

A new class of local linear hazard estimators based on weighted least square kernel estimation is considered. The class includes the kernel hazard estimator of Ramlau-Hansen (1983), which has the same boundary correction property as the local linear regression estimator (see Fan & Gijbels, 1996). It is shown that all the local linear estimators in the class have the same pointwise asymptotic properties. We derive the multiplicative bias correction of the local linear estimator. In addition we propose a new bias correction technique based on bootstrap estimation of additive bias. This latter method has excellent theoretical properties. Based on an extensive simulation study where we compare the performance of competing estimators, we also recommend the use of the additive bias correction in applied work.     

Linearized Ridge Regression Estimator in Linear Regression

In this article, we aim to study the linearized ridge regression (LRR) estimator in a linear regression model motivated by the work of Liu (1993). The LRR estimator and the two types of generalized Liu estimators are investigated under the PRESS criterion. The method of obtaining the optimal generalized ridge regression (GRR) estimator is derived from the optimal LRR estimator. We apply the Hald data as a numerical example and then make a simulation study to show the main results. It is concluded that the idea of transforming the GRR estimator as a complicated function of the biasing parameters to a linearized version should be paid more attention in the future.     

Estimation in a linear regression model with stochastic linear restrictions: a new two-parameter-weighted mixed estimator

The present paper considers the weighted mixed regression estimation of the coefficient vector in a linear regression model with stochastic linear restrictions binding the regression coefficients. We introduce a new two-parameter-weighted mixed estimator (TPWME) by unifying the weighted mixed estimator of Schaffrin and Toutenburg [1] and the two-parameter estimator (TPE) of Özkale and Kaç?ranlar [2]. This new estimator is a general estimator which includes the weighted mixed estimator, the TPE and the restricted two-parameter estimator (RTPE) proposed by Özkale and Kaç?ranlar [2] as special cases. Furthermore, we compare the TPWME with the weighted mixed estimator and the TPE with respect to the matrix mean square error criterion. A numerical example and a Monte Carlo simulation experiment are presented by using different estimators of the biasing parameters to illustrate some of the theoretical results.     

A Spline‐Based Semiparametric Maximum Likelihood Estimation Method for the Cox Model with Interval‐Censored Data

Abstract. We propose a spline‐based semiparametric maximum likelihood approach to analysing the Cox model with interval‐censored data. With this approach, the baseline cumulative hazard function is approximated by a monotone B‐spline function. We extend the generalized Rosen algorithm to compute the maximum likelihood estimate. We show that the estimator of the regression parameter is asymptotically normal and semiparametrically efficient, although the estimator of the baseline cumulative hazard function converges at a rate slower than root‐n. We also develop an easy‐to‐implement method for consistently estimating the standard error of the estimated regression parameter, which facilitates the proposed inference procedure for the Cox model with interval‐censored data. The proposed method is evaluated by simulation studies regarding its finite sample performance and is illustrated using data from a breast cosmesis study.     

Improving survey-weighted least squares regression

The weighted least squares (WLS) estimator is often employed in linear regression using complex survey data to deal with the bias in ordinary least squares (OLS) arising from informative sampling. In this paper a 'quasi-Aitken WLS' (QWLS) estimator is proposed. QWLS modifies WLS in the same way that Cragg's quasi-Aitken estimator modifies OLS. It weights by the usual inverse sample inclusion probability weights multiplied by a parameterized function of covariates, where the parameters are chosen to minimize a variance criterion. The resulting estimator is consistent for the superpopulation regression coefficient under fairly mild conditions and has a smaller asymptotic variance than WLS.