Prenatal Maternal Anxiety and Depression Predict Negative Behavioral Reactivity in Infancy

The effects of maternal antenatal and postnatal anxiety and depression on infant negative behavioral reactivity were examined in a sample of 22 mother‐infant pairs. Maternal anxiety and depression were assessed by standardized measures during the third trimester of pregnancy and postpartum. Infant negative behavioral responses to novelty were assessed using a previously validated measure at 4 months of age. Maternal anxiety and depression during the prenatal, but not the postnatal period, were related to infant negative behavioral reactivity to novelty. These data illustrate that prenatal maternal psychological state can exert persisting influences on human infant behavior.     

Maternal Postpartum Depression Increases Vulnerability for Toddler Behavior Problems through Infant Cortisol Reactivity

The current study examined the role of hypothalamic‐pituitary‐adrenal reactivity (a physiological indicator of stress) in early infancy as a mediator of the relationship between maternal postpartum depression and toddler behavior problems. Participants were 137 at‐risk mothers and their children participating in a longitudinal study of intergenerational transmission of risk. Mothers’ depression was measured five times during the infants’ first 18 months. Infant cortisol was collected during a social stressor (the still‐face paradigm) when infants were 6 months old, and mothers reported on toddlers’ internalizing and externalizing symptoms at 18 months. Among this sample of high‐risk mother–infant dyads, early postpartum depression predicted atypical infant cortisol reactivity at 6 months, which mediated the effect of maternal depression on increased toddler behavior problems. Clinical implications are discussed.     

The Impact of Maternal Characteristics and Sensitivity on the Concordance Between Maternal Reports and Laboratory Observations of Infant Negative Emotionality

The moderating role of maternal characteristics and maternal sensitivity on the concordance between maternal reports and laboratory observations of negative emotionality was examined. Participants were 90 primiparous mothers and their infants. Mothers completed questionnaires about remembered care from their own parents and their depressive symptoms prenatally, infant temperament (distress to novelty and distress to limitations), and depressive symptoms postnatally. Mothers and infants participated in a laboratory assessment of infant temperament (distress to novelty and limitations) and maternal sensitivity at 6 months postpartum. Several factors that moderate the degree of concordance between maternal reports and behavioral observations were identified, as predicted. Novelty concordance was higher when mothers reported having their emotional needs met in childhood and low prenatal depressive symptoms. Limitations concordance was higher when mothers were less sensitive during the observational tasks. Methodological and theoretical implications are discussed.     

Infant Neurodevelopment is Affected by Prenatal Maternal Stress: The QF2011 Queensland Flood Study

Research shows that prenatal maternal stress (PNMS) negatively affects a range of infant outcomes; yet no single study has explored the effects of stress in pregnancy from a natural disaster on multiple aspects of infant neurodevelopment. This study examined the effects of flood‐related stress in pregnancy on 6‐month‐olds' neurodevelopment and examined the moderating effects of timing of the stressor in gestation and infant sex on these outcomes. Women exposed to the 2011 Queensland (Australia) floods in pregnancy completed surveys on their flood‐related objective and subjective experiences at recruitment and reported on their infants' neurodevelopment on the problem solving, communication, and personal–social scales of the Ages and Stages‐III at 6 months postpartum (N = 115). Interaction results showed that subjective flood stress in pregnancy had significantly different effects in boys and girls, and that at high levels of stress girls had significantly lower problem solving scores than boys. Timing of the flood later in pregnancy predicted lower personal–social scores in the sample, and there was a trend (p < .10) for greater objective flood exposure to predict lower scores. PNMS had no effect on infants' communication skills. In conclusion, differential aspects of maternal flood‐related stress in pregnancy influenced aspects of 6‐month‐olds' neurodevelopment.     

Maternal Cocaine Use and Infant Behavior

This study examined the impact of maternal cocaine use and associated risk factors such as polysubstance use, maternal functioning, and caregiving on affect regulation during infancy. Participants were 45 mother‐infant dyads (19 cocaine exposed and 26 control infants) recruited at birth. Observations and maternal reports of infant behavior were obtained at 2 and 7 months of age, along with measures of pre‐ and postnatal substance use, maternal functioning, and caregiving stability. Maternal cocaine use accounted for significant variance in infant positive affect at 2 months. Other substance use and gestational age predicted infant distress to novelty and arousal during developmental assessments. At 7 months, the impact of prenatal cocaine exposure on infant affect regulation was mediated by postnatal alcohol use and caregiving stability. These findings, if replicated, suggest that 1 pathway to later problem behavior reported among substance‐exposed children may be through early regulatory problems and the quality of postnatal caregiving.     

Maternal Sensitivity and Infant Emotional Reactivity

SUMMARY

Although the construct of infant reactivity is thought to be a temperamental dimension, investigators have been interested in the relation between emotional reactivity and maternal behaviors. In this study, infants' emotional reactivity to frustrating stimuli and maternal sensitivity and intrusiveness were observed at 5 and 10 months of age. Cluster analysis of infants' emotional expressions revealed three patterns of expressive behavior emerged at both ages: (1) frequent anger and negative (distress) expressions, (2) intense anger expressions, and (3) frequent happy expressions. Results demonstrated that patterns of emotional reactivity at 5 and 10 months differed by maternal interactive style. In addition, patterns of emotional reactivity at 10 months of age could be predicted by differences in maternal caregiving, and conversely, 5-month infant reactivity was predictive of 10-month maternal behavior. Conclusions are made regarding ways that mothers socialize emotions and the bi-directional nature of mother-infant interactions.     

Associations Between Maternal Postpartum Depression,Infant Social Behavior With a Stranger,and Infant Cognitive Development

Maternal postpartum depression (PPD) has been found to be related to infant social withdrawal during mother–infant interaction, and this may spill over on infant interactive behavior in other social contexts and impact infant psychosocial development. We investigated whether PPD was associated with infant social withdrawal during interaction with a tester in a psychological test situation and whether infant social withdrawal in the test situation mediated the association between PPD and infant cognitive scores reported in a previous study. Participants were 28 PPD dyads and 41 control dyads. We assessed infant social behavior and cognitive development with the Alarm Distress Baby Scale and the cognitive scale of the Bayley Scales of Infant and Toddler Development, third edition, at four months. More symptoms of maternal depression were associated with more infant social withdrawal. The association between maternal depressive symptoms and cognitive scores was at most partially mediated by infant social withdrawal in the test situation (<29.6%). Our results add to the existing literature on the effects of PPD on infant social behavior in other contexts than the one constituted by the mother. More research is needed to shed light on the mechanisms through which PPD impacts infant cognitive development.     

Infant Behavior and Competence Following Prenatal Exposure to a Natural Disaster: The QF2011 Queensland Flood Study

This study utilized a natural disaster to investigate the effects of prenatal maternal stress (PNMS) arising from exposure to a severe flood on maternally reported infant social–emotional and behavioral outcomes at 16 months, along with potential moderation by infant sex and gestational timing of flood exposure. Women pregnant during the Queensland floods in January 2011 completed measures of flood‐related objective hardship and posttraumatic stress (PTS). At 16 months postpartum, mothers completed measures describing depressive symptoms and infant social–emotional and behavioral problems (n = 123) and competence (n = 125). Greater maternal PTS symptoms were associated with reduced infant competence. A sex difference in infant behavioral problems emerged at higher levels of maternal objective hardship and PTS; boys had significantly more behavioral problems than girls. Additionally, greater PTS was associated with more behavioral problems in boys; however, this effect was attenuated by adjustment for maternal depressive symptoms. No main effects or interactions with gestational timing were found. Findings highlight specificity in the relationships between PNMS components and infant outcomes and demonstrate that the effects of PNMS exposure on behavior may be evident as early as infancy. Implications for the support of families exposed to a natural disaster during pregnancy are discussed.     

Racism,Trauma and Positive Aspects of Exposure to Race-Related Experiences

ABSTRACT

Ex po sure to race-re lated ex pe ri ences, such as race-hate as sault and dis crim i nation, are not rou tinely and sys tern at i cally ad dressed in as sess ment and treat ment in ter ventions or in so cial work prac tice formulations. A psychodynamic, ethnocultural, and strengths-ori ented conceptual framework is presented to describe exposure to stressful, traumatic, and positive race-re lated experiences. Criteria are identified for con ducting an in quiry about race-re lated ex pe ri ences to help as sess pos-si ble en vi ron men tal stress ors re lated to pre senting symp toms of Adjustment, Acute Stress or Post-Trau matic Stress Dis or ders. Also, there is an identification of obstacles and factors to consider when in ter viewing about ex po sure to race-re lated ex pe ri ences, and aspe cific in ter view format to guide sys tern atic in quiry about such ex po sure. Finally, sa lient im pli cations for as sess ment, treat ment and re search are de scribed.     

The Regulation of Infant Negative Emotions: The Role of Maternal Sensitivity and Infant‐Directed Speech Prosody

This study explored the role of maternal sensitivity and infant‐directed speech (IDS) prosody in infants’ expression and regulation of negative emotion. Seventy mothers and their 3‐month‐old infants were observed during the Still‐Face Paradigm (SFP). Maternal sensitivity and IDS prosody were assessed at baseline and infant negative affect in the baseline, still‐face, and reunion episodes. Results showed that prototypical IDS prosody characterized by wider fundamental frequency (F0) variability was related to decreases in infant's negative affect, but only if accompanied by maternal sensitivity. Infants of sensitive mothers who spoke with more prototypical IDS prosody showed better abilities to regulate negative affect during the SFP. When prototypical IDS prosody was accompanied by low maternal sensitivity, infants showed lower regulation of negative emotions. In conclusion, infant negative affect regulation in a dyadic setting is facilitated by an optimal combination of both more prototypical maternal IDS prosody and maternal sensitive responsiveness. Implications for the study of mother–infant interaction are discussed.     

Maternal Disrupted Communication During Face‐to‐Face Interaction at 4 months: Relation to Maternal and Infant Cortisol Among at‐Risk Families

The study evaluated the association between maternal disrupted communication and the reactivity and regulation of the psychobiology of the stress response in infancy. Mothers and infants were recruited via the National Health Service from the 20% most economically impoverished data zones in a suburban region of Scotland. Mothers (N = 63; M age = 25.9) and their 4‐month‐old infants (35 boys, 28 girls) were videotaped interacting for 8 min, including a still‐face procedure as a stress inducer and a 5‐min coded recovery period. Saliva samples were collected from the dyads prior to, during, and after the still‐face procedure and later assayed for cortisol. Level of disruption in maternal communication with the infant was coded from the 5‐min videotaped interaction during the recovery period which followed the still‐face procedure. Severely disrupted maternal communication was associated with lower levels of maternal cortisol and a greater divergence between mothers' and infants' cortisol levels. Results point to low maternal cortisol as a possible mechanism contributing to the mother's difficulty in sensitively attuning to her infant's cues, which in turn has implications for the infant's reactivity to and recovery from a mild stressor in early infancy.     

Maternal Age,Psychological Maturity,Parenting Cognitions,and Mother–Infant Interaction

In the context of the trend toward delayed childbearing, the aim of this study was to examine relations among maternal age and the quality of maternal interactive behavior at 7 months assessed using sensitivity and mind‐mindedness, while also considering whether age effects were attributable to psychological maturity and parenting cognitions. Participants were 150 Australian mothers (mean age 33‐years) and their firstborn infants who were participating in a prospective study of parenthood. Path analysis showed maternal age had both direct and indirect associations with maternal interactive behavior. Older mothers made more mind‐related comments to their infants. They were also more sensitive; however, this effect was indirect and explained by greater psychological maturity (hardiness) and a more internal locus of control with regard to parenting. Results suggest that older maternal age may confer some benefits in terms of responsive parenting in infancy.     

Relation Between Maternal Contingent Responsiveness and Infant Social Expectations

This study investigated the relation between maternal contingent responsiveness and 4‐ and 5‐month‐old infants' (N = 64) social expectation behavior in a still‐face procedure. Mothers were asked to interact with their infants for 2 min (interactive phase), remain still‐faced for 1 min (still‐face phase), and resume interaction for 2 min. Mother and infant behavior was assessed for the frequency of infant and mother smiles, mother smiles that were contingent to infant smiles and infant smiles were contingent to mother smiles during the interactive phase, and infant social bids to mother during the still‐face phase. Hierarchical regression showed that mother contingent smiles during the interactive phase accounted for unique variance in infant social bids during the still‐face phase beyond that accounted for by the frequency of mother and infant smiles during the interactive phase. These results support the view that young infants' social expectations and sense of self‐efficacy are formed within their interactions with their caregivers.     

Physiological Reactivity to Infant Crying and Observed Maternal Sensitivity

Relations between maternal sensitivity and physiological reactivity to infant crying were examined using measures of heart rate (HR) and respiratory sinus arrhythmia (RSA) in 49 mothers of second‐born infants. Using the Ainsworth Sensitivity Scale, an independent assessment of maternal sensitivity was made during maternal free play and bathing of their infants. Physiological reactivity was measured while mothers listened to three blocks of infant cry sounds in a standard cry paradigm. Mothers scoring high on sensitivity were compared to less sensitive mothers on both their physiological reactivity to the presented crying sounds and their physiological mean‐level differences. Significant interaction effects were found for both HR and RSA. Highly sensitive mothers showed a larger increase in HR and stronger RSA withdrawal in response to the first block of cry sounds compared to less sensitive mothers. Main effects showed that highly sensitive mothers had lower mean overall HR, and higher mean RSA levels across all three blocks of crying sounds compared to less sensitive mothers. RSA withdrawal and accompanying HR increases are discussed from a polyvagal perspective as indicative of a better capability in responding to infant signals of negative affect.     

Adult Perceptions of Positive and Negative Infant Emotional Expressions

Adults' perceptions provide information about the emotional meaning of infant facial expressions. This study asks whether similar facial movements influence adult perceptions of emotional intensity in both infant positive (smile) and negative (cry face) facial expressions. Ninety‐five college students rated a series of naturally occurring and digitally edited images of infant facial expressions. Naturally occurring smiles and cry faces involving the co‐occurrence of greater lip movement, mouth opening, and eye constriction, were rated as expressing stronger positive and negative emotion, respectively, than expressions without these 3 features. Ratings of digitally edited expressions indicated that eye constriction contributed to higher ratings of positive emotion in smiles (i.e., in Duchenne smiles) and greater eye constriction contributed to higher ratings of negative emotion in cry faces. Stronger mouth opening contributed to higher ratings of arousal in both smiles and cry faces. These findings indicate a set of similar facial movements are linked to perceptions of greater emotional intensity, whether the movements occur in positive or negative infant emotional expressions. This proposal is discussed with reference to discrete, componential, and dynamic systems theories of emotion.     

Maternal Psychosocial Adversity and the Longitudinal Development of Infant Sleep

Research has identified associations between indicators of social disadvantage and the presence of child sleep problems. We examined the longitudinal development of infant sleep in families experiencing high (n = 58) or low (n = 64) levels of psychosocial adversity, and the contributions of neonatal self‐regulatory capacities and maternal settling strategies to this development. Assessments of infant sleep at 4‐, 7‐, and 12‐weeks postpartum indicated no differences in sleeping difficulties between high‐ and low‐adversity groups. However, more infant sleep difficulties were reported in the high‐ versus low‐adversity groups at 12‐ and 18‐month follow‐ups. Neonatal self‐regulatory capacities were not related to the presence or absence of adversity, or to subsequent infant sleep quality. However, there were group differences in maternal settling strategies that did predict subsequent infant sleep difficulties. The pattern of sleep disturbance observed in association with maternal psychosocial adversity at 18‐months was consistent with risk for broader impairments in child functioning.     

The Effects of Unemployment on Prenatal Care Use and Infant Health

Do recessions improve birth outcomes? This study investigated the relationship between unemployment fluctuations, prenatal care utilization and infant health. Analyzing the US Natality Detail Files for the period 1989–1999 aggregated by county, year, and race, I found the overall effects of unemployment to be beneficial but concluded that at least some of the apparent benefits are attributable to the Medicaid “safety net.” In supplementary analyses stratified by socioeconomic status, Medicaid played the largest role among economically disadvantaged (single and less educated) women. Thus, unemployment seems to be good for at least some pregnancies—provided Medicaid steps in.     

Infant Emotionality: Observational Methods and the Validity of Maternal Reports

This study was designed to improve the observational measurement of emotionality, and to test factors that influence the validity of maternal reports. More than 150 infants were visited at home with their mothers, two thirds of whom were depressed. These visits yielded 4 different observational measures of positive and negative emotionality at both 6 and 9 months. These were standard assessments (based on LabTab), naturalistic interactions, atypical reactions to the standard assessments, and the still‐face procedure. Atypical reactions were consistently related to traditional measures of emotionality. Responses to the still‐face procedure also generally cohered with the other measures. Aggregation improved agreement between mothers and observers. Depressed mothers' reports of negative emotionality were less accurate at 6 months than those of nondepressed mothers. Parenting experience appeared to be associated with greater maternal accuracy. Taken together the findings provide some support for both sides of the controversy surrounding the validity of maternal reports.     

Microanalysis of 4-Month Infant Vocal Affect Qualities and Maternal Postpartum Depression

This study examined the association of 6-week maternal self-report depressive symptoms measured by the Center for Epidemiological Studies-Depression Scale (CES-D) with 4-month infant vocal affect qualities. This was part a larger study which examined many additional domains of both infant and maternal behavior. Infant vocal affect qualities were examined in 122 4-month old infants during face-to-face play in relation to 6-week maternal depressive symptoms. Mothers were categorized depressed (26.2%) based on a 16+ cutoff on the CES-D. Videotaped interactions were coded on a 1-s time basis for infant vocal affect qualities (high positive, neutral/positive, fuss/whimper, cry, angry protest and silent.) Infants of depressed mothers were more vocally activated in both positive and negative qualities. In addition, infants of depressed mothers were more vocally variable, specifically in and out of fuss/whimper, as well as more likely to change, rather than maintain vocal states.     

Prenatal Depression and Infant Temperament: The Moderating Role of Placental Gene Expression

Prior research has demonstrated the link between maternal depression during pregnancy (i.e., prenatal depression) and increased neurodevelopmental dysregulation in offspring. However, little is known about the roles of key hypothalamic–pituitary axis regulatory genes in the placenta modulating this association. This study will examine whether placental gene expression levels of 11β‐hydroxysteroid dehydrogenase type 2 (HSD11B2), glucocorticoid receptor (NR3C1), and mineralocorticoid receptor (NR3C2) can help elucidate the underlying mechanisms linking prenatal depression to infant temperament, particularly in infants with high negativity and low emotion regulation. Stored placenta tissues (N = 153) were used to quantify messenger ribonucleic acid levels of HSD11B2, NR3C1, and NR3C2. Assessments of prenatal depression and infant temperament at 6 months of age were ascertained via maternal report. Results found that prenatal depression was associated with increased Negative Affectivity (p < .05) after controlling for postnatal depression and psychosocial characteristics. Furthermore, the association between prenatal depression and Negative Affectivity was moderated by gene expression levels of HSD11B2, NR3C1, and NR3C2 such that greater gene expression significantly lessened the association between prenatal depression and Negative Affectivity. Our findings suggest that individual differences in placental gene expression may be used as an early marker of susceptibility or resilience to prenatal adversity.