An empirical goodness-of-fit test for multivariate distributions

An empirical test is presented as a tool for assessing whether a specified multivariate probability model is suitable to describe the underlying distribution of a set of observations. This test is based on the premise that, given any probability distribution, the Mahalanobis distances corresponding to data generated from that distribution will likewise follow a distinct distribution that can be estimated well by means of a large sample. We demonstrate the effectiveness of the test for detecting departures from several multivariate distributions. We then apply the test to a real multivariate data set to confirm that it is consistent with a multivariate beta model.     

Estimating Individual-Level Risk in Spatial Epidemiology Using Spatially Aggregated Information on the Population at Risk

We propose a novel alternative to case-control sampling for the estimation of individual-level risk in spatial epidemiology. Our approach uses weighted estimating equations to estimate regression parameters in the intensity function of an inhomogeneous spatial point process, when information on risk-factors is available at the individual level for cases, but only at a spatially aggregated level for the population at risk. We develop data-driven methods to select the weights used in the estimating equations and show through simulation that the choice of weights can have a major impact on efficiency of estimation. We develop a formal test to detect non-Poisson behavior in the underlying point process and assess the performance of the test using simulations of Poisson and Poisson cluster point processes. We apply our methods to data on the spatial distribution of childhood meningococcal disease cases in Merseyside, U.K. between 1981 and 2007.     

Inference for cluster point processes with over- or under-dispersed cluster sizes

Cluster point processes comprise a class of models that have been used for a wide range of applications. While several models have been studied for the probability density function of the offspring displacements and the parent point process, there are few examples of non-Poisson distributed cluster sizes. In this paper, we introduce a generalization of the Thomas process, which allows for the cluster sizes to have a variance that is greater or less than the expected value. We refer to this as the cluster sizes being over- and under-dispersed, respectively. To fit the model, we introduce minimum contrast methods and a Bayesian MCMC algorithm. These are evaluated in a simulation study. It is found that using the Bayesian MCMC method, we are in most cases able to detect over- and under-dispersion in the cluster sizes. We use the MCMC method to fit the model to nerve fiber data, and contrast the results to those of a fitted Thomas process.

     

Analysis of Bivariate Survival Data using Shared Inverse Gaussian Frailty Model

In this article, we consider shared frailty model with inverse Gaussian distribution as frailty distribution and log-logistic distribution (LLD) as baseline distribution for bivariate survival times. We fit this model to three real-life bivariate survival data sets. The problem of analyzing and estimating parameters of shared inverse Gaussian frailty is the interest of this article and then compare the results with shared gamma frailty model under the same baseline for considered three data sets. Data are analyzed using Bayesian approach to the analysis of clustered survival data in which there is a dependence of failure time observations within the same group. The variance component estimation provides the estimated dispersion of the random effects. We carried out a test for frailty (or heterogeneity) using Bayes factor. Model comparison is made using information criteria and Bayes factor. We observed that the shared inverse Gaussian frailty model with LLD as baseline is the better fit for all three bivariate data sets.     

The two-sided power-binomial distribution for modeling binary count data

The two-sided power (TSP) distribution is a flexible two-parameter distribution having uniform, power function and triangular as sub-distributions, and it is a reasonable alternative to beta distribution in some cases. In this work, we introduce the TSP-binomial model which is defined as a mixture of binomial distributions, with the binomial parameter p having a TSP distribution. We study its distributional properties and demonstrate its use on some data. It is shown that the newly defined model is a useful candidate for overdispersed binomial data.     

A new useful three-parameter extension of the exponential distribution

A three-parameter extension of the exponential distribution is introduced and studied in this paper. The new distribution is quite flexible and can be used effectively in modelling survival data, reliability problems, fatigue life studies and hydrological data. It can have constant, decreasing, increasing, upside-down bathtub (unimodal), bathtub-shaped and decreasing–increasing–decreasing hazard rate functions. We provide a comprehensive account of the mathematical properties of the new distribution and various structural quantities are derived. We discuss maximum likelihood estimation of the model parameters for complete sample and for censored sample. An empirical application of the new model to real data is presented for illustrative purposes. We hope that the new distribution will serve as an alternative model to other models available in the literature for modelling real data in many areas.     

The McDonald arcsine distribution: a new model to proportional data

We propose a new three-parameter continuous model called the McDonald arcsine distribution, which is a very competitive model to the beta, beta type I and Kumaraswamy distributions for modelling rates and proportions. We provide a mathematical treatment of the new distribution including explicit expressions for the density function, moments, generating and quantile functions, mean deviations, two probability measures based on the Bonferroni and Lorenz curves, Shannon entropy, Rényi entropy and cumulative residual entropy. Maximum likelihood is used to estimate the model parameters and the expected information matrix is determined. An application of the proposed model to real data shows that it can give consistently a better fit than other important statistical models.     

The Poisson Generalized Linear Failure Rate Model

We formulate a new cure rate survival model by assuming that the number of competing causes of the event of interest has the Poisson distribution, and the time to this event has the generalized linear failure rate distribution. A new distribution to analyze lifetime data is defined from the proposed cure rate model, and its quantile function as well as a general expansion for the moments is derived. We estimate the parameters of the model with cure rate in the presence of covariates for censored observations using maximum likelihood and derive the observed information matrix. We obtain the appropriate matrices for assessing local influence on the parameter estimates under different perturbation schemes and present some ways to perform global influence analysis. The usefulness of the proposed cure rate survival model is illustrated in an application to real data.     

A study of R2 measure under the accelerated failure time models

For right-censored data, the accelerated failure time (AFT) model is an alternative to the commonly used proportional hazards regression model. It is a linear model for the (log-transformed) outcome of interest, and is particularly useful for censored outcomes that are not time-to-event, such as laboratory measurements. We provide a general and easily computable definition of the R² measure of explained variation under the AFT model for right-censored data. We study its behavior under different censoring scenarios and under different error distributions; in particular, we also study its robustness when the parametric error distribution is misspecified. Based on Monte Carlo investigation results, we recommend the log-normal distribution as a robust error distribution to be used in practice for the parametric AFT model, when the R² measure is of interest. We apply our methodology to an alcohol consumption during pregnancy data set from Ukraine.     

The gamma-exponentiated exponential distribution

In this paper, we introduce a new distribution generated by gamma random variables. We show that this distribution includes as a special case the distribution of the lower record value from a sequence of i.i.d. random variables from a population with the exponentiated (generalized) exponential distribution. The properties of this distribution are derived and the estimation of the model parameters is discussed. Some applications to real data sets are finally presented for illustration.     

The exponentiated-log-logistic geometric distribution: Dual activation

ABSTRACT

The log-logistic distribution is commonly used to model lifetime data. We propose a wider distribution, named the exponentiated log-logistic geometric distribution, based on a double activation approach. We obtain the quantile function, ordinary moments, and generating function. The method of maximum likelihood is used to estimate the model parameters. We propose a new extended regression model based on the logarithm of the exponentiated log-logistic geometric distribution. This regression model can be very useful in the analysis of real data and could provide better fits than other special regression models. The potentiality of the new models is illustrated by means of two applications to real lifetime data sets.     

The negative binomial–beta Weibull regression model to predict the cure of prostate cancer

In this article, for the first time, we propose the negative binomial–beta Weibull (BW) regression model for studying the recurrence of prostate cancer and to predict the cure fraction for patients with clinically localized prostate cancer treated by open radical prostatectomy. The cure model considers that a fraction of the survivors are cured of the disease. The survival function for the population of patients can be modeled by a cure parametric model using the BW distribution. We derive an explicit expansion for the moments of the recurrence time distribution for the uncured individuals. The proposed distribution can be used to model survival data when the hazard rate function is increasing, decreasing, unimodal and bathtub shaped. Another advantage is that the proposed model includes as special sub-models some of the well-known cure rate models discussed in the literature. We derive the appropriate matrices for assessing local influence on the parameter estimates under different perturbation schemes. We analyze a real data set for localized prostate cancer patients after open radical prostatectomy.     

The McDonald Weibull model

For the first time, we propose a five-parameter lifetime model called the McDonald Weibull distribution to extend the Weibull, exponentiated Weibull, beta Weibull and Kumaraswamy Weibull distributions, among several other models. We obtain explicit expressions for the ordinary moments, quantile and generating functions, mean deviations and moments of the order statistics. We use the method of maximum likelihood to fit the new distribution and determine the observed information matrix. We define the log-McDonald Weibull regression model for censored data. The potentiality of the new model is illustrated by means of two real data sets.     

Prediction distribution for a linear regression model with multivariate student-t error distribution

The distribution(s) of future response(s) given a set of data from an informative experiment is known as prediction distribution. The paper derives the prediction distribution(s) from a linear regression model with a multivari-ate Student-t error distribution using the structural relations of the model. We observe that the prediction distribution(s) are multivariate t-variate(s) with degrees of freedom which do not depend on the degrees of freedom of the error distribution.     

A parametric model for heterogeneity in paired Poisson counts

We present a model for data in the form of matched pairs of counts. Our work is motivated by a problem in fission-track analysis, where the determination of a crystal's age is based on the ratio of counts of spontaneous and induced tracks. It is often reasonable to assume that the counts follow a Poisson distribution, but typically they are overdispersed and there exists a positive correlation between the numbers of spontaneous and induced tracks in the same crystal. We propose a model that allows for both overdispersion and correlation by assuming that the mean densities follow a bivariate Wishart distribution. Our model is quite general, having the usual negative-binomial and Poisson models as special cases. We propose a maximum-likelihood estimation method based on a stochastic implementation of the EM algorithm, and we derive the asymptotic standard errors of the parameter estimates. We illustrate the method with a data set of fission-track counts in matched areas of zircon crystals.     

The modified Fréchet distribution and its properties

The Fréchet distribution is an absolutely continuous model which has wide applicability in extreme value theory. In this paper, we propose a new three-parameter model, so-called the modified Fréchet distribution, to extend the Fréchet distribution. By using the Lambert function, we obtain some properties of the new distribution. We provide a simulation study to illustrate the performance of the maximum likelihood estimates. The flexibility of the introduced distribution is illustrated by means of a real data set. We use some goodness-of-fit statistics to verify the adequacy of the proposed model. We prove empirically that it is appropriate for lifetime applications.     

The beta exponentiated Weibull distribution

The Weibull distribution is one of the most important distributions in reliability. For the first time, we introduce the beta exponentiated Weibull distribution which extends recent models by Lee et al. [Beta-Weibull distribution: some properties and applications to censored data, J. Mod. Appl. Statist. Meth. 6 (2007), pp. 173–186] and Barreto-Souza et al. [The beta generalized exponential distribution, J. Statist. Comput. Simul. 80 (2010), pp. 159–172]. The new distribution is an important competitive model to the Weibull, exponentiated exponential, exponentiated Weibull, beta exponential and beta Weibull distributions since it contains all these models as special cases. We demonstrate that the density of the new distribution can be expressed as a linear combination of Weibull densities. We provide the moments and two closed-form expressions for the moment-generating function. Explicit expressions are derived for the mean deviations, Bonferroni and Lorenz curves, reliability and entropies. The density of the order statistics can also be expressed as a linear combination of Weibull densities. We obtain the moments of the order statistics. The expected information matrix is derived. We define a log-beta exponentiated Weibull regression model to analyse censored data. The estimation of the parameters is approached by the method of maximum likelihood. The usefulness of the new distribution to analyse positive data is illustrated in two real data sets.     

Slashed generalized Rayleigh distribution

We introduce a new family of distributions suitable for fitting positive data sets with high kurtosis which is called the Slashed Generalized Rayleigh Distribution. This distribution arises as the quotient of two independent random variables, one being a generalized Rayleigh distribution in the numerator and the other a power of the uniform distribution in the denominator. We present properties and carry out estimation of the model parameters by moment and maximum likelihood (ML) methods. Finally, we conduct a small simulation study to evaluate the performance of ML estimators and analyze real data sets to illustrate the usefulness of the new model.     

The log-exponentiated generalized gamma regression model for censored data

For the first time, we introduce a generalized form of the exponentiated generalized gamma distribution [Cordeiro et al. The exponentiated generalized gamma distribution with application to lifetime data, J. Statist. Comput. Simul. 81 (2011), pp. 827–842.] that is the baseline for the log-exponentiated generalized gamma regression model. The new distribution can accommodate increasing, decreasing, bathtub- and unimodal-shaped hazard functions. A second advantage is that it includes classical distributions reported in the lifetime literature as special cases. We obtain explicit expressions for the moments of the baseline distribution of the new regression model. The proposed model can be applied to censored data since it includes as sub-models several widely known regression models. It therefore can be used more effectively in the analysis of survival data. We obtain maximum likelihood estimates for the model parameters by considering censored data. We show that our extended regression model is very useful by means of two applications to real data.     

The Kumaraswamy Burr XII distribution: theory and practice

For the first time, a five-parameter distribution, called the Kumaraswamy Burr XII (KwBXII) distribution, is defined and studied. The new distribution contains as special models some well-known distributions discussed in lifetime literature, such as the logistic, Weibull and Burr XII distributions, among several others. We obtain the complete moments, incomplete moments, generating and quantile functions, mean deviations, Bonferroni and Lorenz curves and reliability of the KwBXII distribution. We provide two representations for the moments of the order statistics. The method of maximum likelihood and a Bayesian procedure are adopted for estimating the model parameters. For different parameter settings and sample sizes, various simulation studies are performed and compared to the performance of the KwBXII distribution. Three applications to real data sets demonstrate the usefulness of the proposed distribution and that it may attract wider applications in lifetime data analysis.