Simultaneous confidence intervals by iteratively adjusted alpha for relative effects in the one-way layout

A bootstrap based method to construct 1−α simultaneous confidence intervals for relative effects in the one-way layout is presented. This procedure takes the stochastic correlation between the test statistics into account and results in narrower simultaneous confidence intervals than the application of the Bonferroni correction. Instead of using the bootstrap distribution of a maximum statistic, the coverage of the confidence intervals for the individual comparisons are adjusted iteratively until the overall confidence level is reached. Empirical coverage and power estimates of the introduced procedure for many-to-one comparisons are presented and compared with asymptotic procedures based on the multivariate normal distribution.     

EMPIRICAL LIKELIHOOD METHODS FOR THE GINI INDEX

The Gini index and its generalizations have been used extensively for measuring inequality and poverty in the social sciences. Recently, interval estimation based on nonparametric statistics has been proposed in the literature, for example the naive bootstrap method, the iterated bootstrap method and the bootstrap method via a pivotal statistic. In this paper, we propose empirical likelihood methods to construct confidence intervals for the Gini index or the difference of two Gini indices. Simulation studies show that the proposed empirical likelihood method performs slightly worse than the bootstrap method based on a pivotal statistic in terms of coverage accuracy, but it requires less computation. However, the bootstrap calibration of the empirical likelihood method performs better than the bootstrap method based on a pivotal statistic.     

Reliability inference for a general lower-truncated family of distributions under records

Based on record values, point and interval estimators are proposed in this paper for the parameters of a general lower-truncated family of distributions. Maximum likelihood and bias-corrected estimators are obtained for unknown model parameters. Based on a sufficient and complete statistic, the bias-corrected estimator is also shown to be uniformly minimum variance unbiased estimator. Different exact confidence intervals and exact confidence regions are constructed for the both model and truncated parameters, and other confidence interval estimates based on asymptotic distribution theory and bootstrap approaches are obtained as well. Finally, two real-life examples and a numerical study are presented to illustrate the performance of our methods.     

Comparisons of approximate confidence intervals for the smallest extreme value distribution simple linear regression model under time censoring

Exact confidence interval estimation for accelerated life regression models with censored smallest extreme value (or Weibull) data is often impractical. This paper evaluates the accuracy of approximate confidence intervals based on the asymptotic normality of the maximum likelihood estimator, the asymptotic X²distribution of the likelihood ratio statistic, mean and variance correction to the likelihood ratio statistic, and the so-called Bartlett correction to the likelihood ratio statistic. The Monte Carlo evaluations under various degrees of time censoring show that uncorrected likelihood ratio intervals are very accurate in situations with heavy censoring. The benefits of mean and variance correction to the likelihood ratio statistic are only realized with light or no censoring. Bartlett correction tends to result in conservative intervals. Intervals based on the asymptotic normality of maximum likelihood estimators are anticonservative and should be used with much caution.     

A general bootstrap algorithm for hypothesis testing

The bootstrap is a intensive computer-based method originally mainly devoted to estimate the standard deviations, confidence intervals and bias of the studied statistic. This technique is useful in a wide variety of statistical procedures, however, its use for hypothesis testing, when the data structure is complex, is not straightforward and each case must be particularly treated. A general bootstrap method for hypothesis testing is studied. The considered method preserves the data structure of each group independently and the null hypothesis is only used in order to compute the bootstrap statistic values (not at the resampling, as usual). The asymptotic distribution is developed and several case studies are discussed.     

Likelihood inference for lognormal data with left truncation and right censoring with an illustration

The lognormal distribution is quite commonly used as a lifetime distribution. Data arising from life-testing and reliability studies are often left truncated and right censored. Here, the EM algorithm is used to estimate the parameters of the lognormal model based on left truncated and right censored data. The maximization step of the algorithm is carried out by two alternative methods, with one involving approximation using Taylor series expansion (leading to approximate maximum likelihood estimate) and the other based on the EM gradient algorithm (Lange, 1995). These two methods are compared based on Monte Carlo simulations. The Fisher scoring method for obtaining the maximum likelihood estimates shows a problem of convergence under this setup, except when the truncation percentage is small. The asymptotic variance-covariance matrix of the MLEs is derived by using the missing information principle (Louis, 1982), and then the asymptotic confidence intervals for scale and shape parameters are obtained and compared with corresponding bootstrap confidence intervals. Finally, some numerical examples are given to illustrate all the methods of inference developed here.     

Mid-P confidence intervals based on the likelihood ratio for proportions estimated by group testing

Group testing has been used in many fields of study to estimate proportions. When groups are of different size, the derivation of exact confidence intervals is complicated by the lack of a unique ordering of the event space. An exact interval estimation method is described here, in which outcomes are ordered according to a likelihood ratio statistic. The method is compared with another exact method, in which outcomes are ordered by their associated MLE. Plots of the P‐value against the proportion are useful in examining the properties of the methods. Coverage provided by the intervals is assessed using several realistic grouptesting procedures. The method based on the likelihood ratio, with a mid‐P correction, is shown to give very good coverage in terms of closeness to the nominal level, and is recommended for this type of problem.     

Censored median regression and profile empirical likelihood

We implement profile empirical likelihood-based inference for censored median regression models. Inference for any specified subvector is carried out by profiling out the nuisance parameters from the “plug-in” empirical likelihood ratio function proposed by Qin and Tsao. To obtain the critical value of the profile empirical likelihood ratio statistic, we first investigate its asymptotic distribution. The limiting distribution is a sum of weighted chi square distributions. Unlike for the full empirical likelihood, however, the derived asymptotic distribution has intractable covariance structure. Therefore, we employ the bootstrap to obtain the critical value, and compare the resulting confidence intervals with the ones obtained through Basawa and Koul’s minimum dispersion statistic. Furthermore, we obtain confidence intervals for the age and treatment effects in a lung cancer data set.     

On estimating the variance of a U-statistic

We compare jackknifing and bootstrapping as methods for estimating the variance of a U-statistic. The use of these estimates in calculating asymptotic confidence intervals is discussed, and the results of a numerical study involving Kendall's tau are reported. For the special case of this statistic, the bootstrap is the estimate of choice.     

Comparing point and interval estimates in the bivariate <Emphasis Type="Italic">t</Emphasis>-copula model with application to financial data

The paper considers joint maximum likelihood (ML) and semiparametric (SP) estimation of copula parameters in a bivariate t-copula. Analytical expressions for the asymptotic covariance matrix involving integrals over special functions are derived, which can be evaluated numerically. These direct evaluations of the Fisher information matrix are compared to Hessian evaluations based on numerical differentiation in a simulation study showing a satisfactory performance of the computationally less demanding Hessian evaluations. Individual asymptotic confidence intervals for the t-copula parameters and the corresponding tail dependence coefficient are derived. For two financial datasets these confidence intervals are calculated using both direct evaluation of the Fisher information and numerical evaluation of the Hessian matrix. These confidence intervals are compared to parametric and nonparametric BCA bootstrap intervals based on ML and SP estimation, respectively, showing a preference for asymptotic confidence intervals based on numerical Hessian evaluations.     

Empirical likelihood‐based inference for genetic mixture models

The authors show how the genetic effect of a quantitative trait locus can be estimated by a nonparametric empirical likelihood method when the phenotype distributions are completely unspecified. They use an empirical likelihood ratio statistic for testing the genetic effect and obtaining confidence intervals. In addition to studying the asymptotic properties of these procedures, the authors present simulation results and illustrate their approach with a study on breast cancer resistance genes.     

Stationary bootstrapping for realized covariations of high frequency financial data

This paper studies the stationary bootstrap applicability for realized covariations of high frequency asynchronous financial data. The stationary bootstrap method, which is characterized by a block-bootstrap with random block length, is applied to estimate the integrated covariations. The bootstrap realized covariance, bootstrap realized regression coefficient and bootstrap realized correlation coefficient are proposed, and the validity of the stationary bootstrapping for them is established both for large sample and for finite sample. Consistencies of bootstrap distributions are established, which provide us valid stationary bootstrap confidence intervals. The bootstrap confidence intervals do not require a consistent estimator of a nuisance parameter arising from nonsynchronous unequally spaced sampling while those based on a normal asymptotic theory require a consistent estimator. A Monte-Carlo comparison reveals that the proposed stationary bootstrap confidence intervals have better coverage probabilities than those based on normal approximation.     

Testing the rate ratio under inverse sampling based on gradient statistic

Inverse sampling is widely applied in studies with dichotomous outcomes, especially when the subjects arrive sequentially or the response of interest is difficult to obtain. In this paper, we investigate the rate ratio test problem under inverse sampling based on gradient statistic with the asymptotic method and parametric bootstrap technique. The gradient statistic has many advantages, for example, it is simple to calculate and competitive with Wald-type, score and likelihood ratio tests in terms of local power. Numerical studies are carried out to evaluate the performance of our gradient test and the existing tests, namely Wald-type, score and likelihood ratio tests. The simulation results suggest that the gradient test based on the parametric bootstrap method has excellent type I error control and large powers even in small sample design. Two real examples, from a heart disease study and a drug comparison study, are applied to illustrate our methods.     

Bootstrap confidence intervals in mixtures of discrete distributions

The problem of building bootstrap confidence intervals for small probabilities with count data is addressed. The law of the independent observations is assumed to be a mixture of a given family of power series distributions. The mixing distribution is estimated by nonparametric maximum likelihood and the corresponding mixture is used for resampling. We build percentile-t and Efron percentile bootstrap confidence intervals for the probabilities and we prove their consistency in probability. The new theoretical results are supported by simulation experiments for Poisson and geometric mixtures. We compare percentile-t and Efron percentile bootstrap intervals with eight other bootstrap or asymptotic theory based intervals. It appears that Efron percentile bootstrap intervals outperform the competitors in terms of coverage probability and length.     

Balanced Confidence Regions Based on Tukey's Depth and the Bootstrap

We propose and study the bootstrap confidence regions for multivariate parameters based on Tukey's depth. The bootstrap is based on the normalized or Studentized statistic formed from an independent and identically distributed random sample obtained from some unknown distribution in R ^q . The bootstrap points are deleted on the basis of Tukey's depth until the desired confidence level is reached. The proposed confidence regions are shown to be second order balanced in the context discussed by Beran. We also study the asymptotic consistency of Tukey's depth-based bootstrap confidence regions. The applicability of the method proposed is demonstrated in a simulation study.     

Some Further Issues Concerning Likelihood Inference for Left Truncated and Right Censored Lognormal Data

The maximum likelihood estimates (MLEs) of the parameters of a two-parameter lognormal distribution with left truncation and right censoring are developed through the Expectation Maximization (EM) algorithm. For comparative purpose, the MLEs are also obtained by the Newton–Raphson method. The asymptotic variance-covariance matrix of the MLEs is obtained by using the missing information principle, under the EM framework. Then, using asymptotic normality of the MLEs, asymptotic confidence intervals for the parameters are constructed. Asymptotic confidence intervals are also obtained using the estimated variance of the MLEs by the observed information matrix, and by using parametric bootstrap technique. Different confidence intervals are then compared in terms of coverage probabilities, through a Monte Carlo simulation study. A prediction problem concerning the future lifetime of a right censored unit is also considered. A numerical example is given to illustrate all the inferential methods developed here.     

Robust confidence regions for multinomial probabilities

Generally, confidence regions for the probabilities of a multinomial population are constructed based on the Pearson χ² statistic. Morales et al. (Bootstrap confidence regions in multinomial sampling. Appl Math Comput. 2004;155:295–315) considered the bootstrap and asymptotic confidence regions based on a broader family of test statistics known as power-divergence test statistics. In this study, we extend their work and propose penalized power-divergence test statistics-based confidence regions. We only consider small sample sizes where asymptotic properties fail and alternative methods are needed. Both bootstrap and asymptotic confidence regions are constructed. We consider the percentile and the bias corrected and accelerated bootstrap confidence regions. The latter confidence region has not been studied previously for the power-divergence statistics much less for the penalized ones. Designed simulation studies are carried out to calculate average coverage probabilities. Mean absolute deviation between actual and nominal coverage probabilities is used to compare the proposed confidence regions.     

Bootstrap confidence intervals for smoothing splines and their comparison to bayesian confidence intervals

We construct bootstrap confidence intervals for smoothing spline estimates based on Gaussian data, and penalized likelihood smoothing spline estimates based on data from .exponential families. Several vari- ations of bootstrap confidence intervals are considered and compared. We find that the commonly used ootstrap percentile intervals are inferior to the T intervals and to intervals based on bootstrap estimation of mean squared errors. The best variations of the bootstrap confidence intervals behave similar to the well known Bayesian confidence intervals. These bootstrap confidence intervals have an average coverage probability across the function being estimated, as opposed to a pointwise property.     

Exact Likelihood Inference for Two Exponential Populations Under Joint Progressive Type-II Censoring

Comparative lifetime experiments are of great importance when the interest is in ascertaining the relative merits of two competing products with regard to their reliability. In this article, we consider two exponential populations and when joint progressive Type-II censoring is implemented on the two samples. We then derive the moment generating functions and the exact distributions of the maximum likelihood estimators (MLEs) of the mean lifetimes of the two exponential populations under such a joint progressive Type-II censoring. We then discuss the exact lower confidence bounds, exact confidence intervals, and simultaneous confidence regions. Next, we discuss the corresponding approximate results based on the asymptotic normality of the MLEs as well as those based on the Bayesian method. All these confidence intervals and regions are then compared by means of Monte Carlo simulations with those obtained from bootstrap methods. Finally, an illustrative example is presented in order to illustrate all the methods of inference discussed here.     

Robust simultaneous confidence interval estimation of principal component loadings

We propose a method that integrates bootstrap into the forward search algorithm in the construction of robust confidence intervals for elements of the eigenvectors of the correlation matrix in the presence of outliers. Coverage probability of the bootstrap simultaneous confidence intervals was compared to the coverage probabilities of regular asymptotic confidence region and asymptotic confidence region based on the minimum covariance determinant (MCD) approach through a simulation study. The method produced more stable coverage probabilities for datasets with or without outliers and across several sample sizes compared to approaches based on asymptotic confidence regions.