Divergence-based estimation and testing with misclassified data

The well-known chi-squared goodness-of-fit test for a multinomial distribution is generally biased when the observations are subject to misclassification. In Pardo and Zografos (2000) the problem was considered using a double sampling scheme and ø-divergence test statistics. A new problem appears if the null hypothesis is not simple because it is necessary to give estimators for the unknown parameters. In this paper the minimum ø-divergence estimators are considered and some of their properties are established. The proposed ø-divergence test statistics are obtained by calculating ø-divergences between probability density functions and by replacing parameters by their minimum ø-divergence estimators in the derived expressions. Asymptotic distributions of the new test statistics are also obtained. The testing procedure is illustrated with an example.     

Adjusted homogeneity tests of odds ratios when data are clustered

Three modified tests for homogeneity of the odds ratio for a series of 2 × 2 tables are studied when the data are clustered. In the case of clustered data, the standard tests for homogeneity of odds ratios ignore the variance inflation caused by positive correlation among responses of subjects within the same cluster, and therefore have inflated Type I error. The modified tests adjust for the variance inflation in the three existing standard tests: Breslow–Day, Tarone and the conditional score test. The degree of clustering effect is measured by the intracluster correlation coefficient, ρ. A variance correction factor derived from ρ is then applied to the variance estimator in the standard tests of homogeneity of the odds ratio. The proposed tests are an application of the variance adjustment method commonly used in correlated data analysis and are shown to maintain the nominal significance level in a simulation study. Copyright © 2004 John Wiley & Sons, Ltd.     

Improved tests for homogeneity of variances

Equality of variances is one of the key assumptions of analysis of variances (ANOVA). There are several testing procedures available to validate this assumption, but it is rare to find a test procedure which controls the type I error rate while providing high statistical power. In this article, we introduce a bootstrap test based on the ratio of mean absolute deviances (RMD). We also propose a two-stage testing procedure where we first quantify the skewness of the distributions and then choose an appropriate test for homogeneity of variances. The performances of these test procedures are studied via a simulation study.     

Theoretical properties of tests for spatial clustering of count data

Testing for spatial clustering of count data is an important problem in spatial data analysis. Several procedures have been proposed to this end but despite their extensive use, studies of their fundamental theoretical properties are almost non‐existent. The authors suggest two conditions that any reasonable test for spatial clustering should satisfy. The latter are based on the notion that the null hypothesis should be rejected almost surely as the amount of spatial clustering tends to infinity. The authors show that the chisquared test and the Potthoff—Whittinghill V have both properties but that other classical tests do not.     

Adaptive Neyman's smooth tests of homogeneity of two samples of survival data

The problem of testing whether two samples of possibly right-censored survival data come from the same distribution is considered. The aim is to develop a test which is capable of detection of a wide spectrum of alternatives. A new class of tests based on Neyman's embedding idea is proposed. The null hypothesis is tested against a model where the hazard ratio of the two survival distributions is expressed by several smooth functions. A data-driven approach to the selection of these functions is studied. Asymptotic properties of the proposed procedures are investigated under fixed and local alternatives. Small-sample performance is explored via simulations which show that the power of the proposed tests appears to be more robust than the power of some versatile tests previously proposed in the literature (such as combinations of weighted logrank tests, or Kolmogorov–Smirnov tests).     

Remarks on tests of homogeneity

Relations between tests constructed in a recent paper in this journal (Johnson and Kotz, J. Statist. Plann. Inference 41 (1994) 61- 72) and an earlier paper by Nikitina (in: V.V. Nalimov, ed., Regression Experiments (Moscow Univ. Press, Moscow, 1977)) are discussed.     

Permutation tests for homogeneity based on some characterizations

In this work, non parametric tests are proposed for testing the homogeneity of two or more populations. The tests are based on recently obtained characterizations. The test procedure is based on the permutation bootstrap technique. For the two-sample case the new tests are compared with permutation tests based on the empirical characteristic function and some other tests. The comparison is fulfilled via a Monte Carlo simulation.     

Two non-parametric, analysis-of-means-type tests for homogeneity of variances

After a brief review of the literature, two non-parametric tests for homogeneity of variances are presented. The first test is based on the analysis of means for ranks, which is a non-parametric version of the analysis of means (ANOM) that uses ranks as input for an ANOM test. The second test uses inverse normal scores of the ranks of scale transformations of the observations as input to the ANOM. Both homogeneity of variances tests can be presented in a graphical form, which makes it easy for practitioners to assess the practical and the statistical significance. A Monte Carlo study is used to show that these tests have power comparable with that of well-known robust tests for homogeneity of variances.     

Generalized orthogonal contrast tests for homogeneity of ordered means

Several procedures have been proposed for testing equality of ordered means. The best-known of these is the likelihood-ratio test introduced by Bartholomew, which possesses generally superior power characteristics to those of its competitors. Difficulties in implementing this test have led to the development of alternative approaches, such as tests based on single and multiple contrasts. Some recent approaches have utilized approximations to the polyhedral cone defining the restricted parameter space, including those of Akkerboom (circular cone) and Mudholkar & McDermott (orthant). This article proposes a class of tests based on an improved orthant approximation to the polyhedral cone. These tests may be viewed as generalizations of the orthogonal contrast test proposed by Mukerjee, Robertson & Wright. Studies of the power functions of several competing tests indicate that the generalized orthogonal contrast tests are effective alternatives to the likelihood-ratio test, especially when the latter is difficult to implement.     

Score test of homogeneity for survival data

If follow-up is made for subjects which are grouped into units, such as familial or spatial units then it may be interesting to test whether the groups are homogeneous (or independent for given explanatory variables). The effect of the groups is modelled as random and we consider a frailty proportional hazards model which allows to adjust for explanatory variables. We derive the score test of homogeneity from the marginal partial likelihood and it turns out to be the sum of a pairwise correlation term of martingale residuals and an overdispersion term. In the particular case where the sizes of the groups are equal to one, this statistic can be used for testing overdispersion. The asymptotic variance of this statistic is derived using counting process arguments. An extension to the case of several strata is given. The resulting test is computationally simple; its use is illustrated using both simulated and real data. In addition a decomposition of the score statistic is proposed as a sum of a pairwise correlation term and an overdispersion term. The pairwise correlation term can be used for constructing a statistic more robust to departure from the proportional hazard model, and the overdispesion term for constructing a test of fit of the proportional hazard model.     

A comparison of tests of homogeneity for sparse contingency tables

Five tests of homogeneity for a 2x(k+l) contingency table are compared using Monte Carlo techniques. For these studiesit is assumed that k becomes large in such a way that thecontingency table is sparse for 2xk of the cells, but the sample size in two of the cells remains large. The test statistics studied are: the chi-square approximation to the Pearson test statistic, the chi-square approximation to the likelihood ratio statistic, the normal approximation to Zelterman's (1984)the normal approximation to Pearson's chi-square, and the normal approximation to the likelihood ratio statistic. For the range of parameters studied the chi-square approximation to Pearson's statistic performs consistently well with regard to its size and power.     

Partitioned log-rank tests for the overall homogeneity of hazard rate functions

In survival analysis, it is routine to test equality of two survival curves, which is often conducted by using the log-rank test. Although it is optimal under the proportional hazards assumption, the log-rank test is known to have little power when the survival or hazard functions cross. To test the overall homogeneity of hazard rate functions, we propose a group of partitioned log-rank tests. By partitioning the time axis and taking the supremum of the sum of two partitioned log-rank statistics over different partitioning points, the proposed test gains enormous power for cases with crossing hazards. On the other hand, when the hazards are indeed proportional, our test still maintains high power close to that of the optimal log-rank test. Extensive simulation studies are conducted to compare the proposed test with existing methods, and three real data examples are used to illustrate the commonality of crossing hazards and the advantages of the partitioned log-rank tests.     

Simultaneous tests for homogeneity of two zero-inflated (beta) populations

ABSTRACT

Motivated by an example in marine science, we use Fisher’s method to combine independent likelihood ratio tests (LRTs) and asymptotic independent score tests to assess the equivalence of two zero-inflated Beta populations (mixture distributions with three parameters). For each test, test statistics for the three individual parameters are combined into a single statistic to address the overall difference between the two populations. We also develop non parametric and semiparametric permutation-based tests for simultaneously comparing two or three features of unknown populations. Simulations show that the likelihood-based tests perform well for large sample sizes and that the statistics based on combining LRT statistics outperforms the ones based on combining score test statistics. The permutation-based tests have overall better performance in terms of both power and type I error rate. Our methods are easy to implement and computationally efficient, and can be expanded to more than two populations and to other multiple parameter families. The permutation tests are entirely generic and can be useful in various applications dealing with zero (or other) inflation.     

A note on homogeneity tests of covariance matrices

In this note we propose two procedures for testing homogeneity of co-variance matrices that are both extensions of Hartley's (1940) test for equality of variances. The first is a two-stage procedure where the first step is a simple test for equality of the largest eigenvalues, and corresponding eigenvectors, of the covariance matrices. The second is based on projection pursuit and seems harder to apply in practice.     

Small sample size comparisons of tests for homogeneity of variances by Monte-Carlo

A number of tests are available for testing the equality of several population variances. Some are claimed to be robust. We compared six of those claimed robust procedures by Monte Carlo simulated experiments, particularly for cases of small and unequal sample sizes. Our results show that the jack-knife test compares favorably with the other tests.     

Linear rank tests for homogeneity against ordered alternatives in anova and anocova

A unified method of constructing rank tests for homogeneity against ordered alternatives in unbalanced analysis of variance and analysis of covariance is considered. The relationship between these tests with some of the existing methods are studied. The normal theory likelihood ratio tests are also derived and the asymptotic relative efficiency comparisons, in Pitman sense, of the rank tests with respect to the likelihood ratio tests are carried out.     

Testing marginal homogeneity in clustered matched-pair data

For general matched-pair data with polytomous responses in biomedical research, the Stuart–Maxwell test (Stuart, 1955, Maxwell, 1970) and the Bhapkar (1966) test are commonly used for evaluating marginal homogeneity. For data collected in clusters, we propose extensions for statistical inference without structural within-cluster correlation or distributional assumptions. Meanwhile, two extended Obuchowski tests are proposed based on the work of Obuchowski (1998) generally applied to clustered matched-pair binary data. A Monte Carlo simulation study illustrates that our proposed extension to the Stuart–Maxwell test and the two extended Obuchowski tests perform well with respect to the power and the nominal size, though the extended Bhapkar test is asymptotically equivalent to the other three tests, it is not recommended in practice due to its being liberal in the nominal size.     

Goodness of fit and homogeneity tests on the basis of N-distances

In this paper we propose an application of N-distance theory [Klebanov, L.B., 2005. N-distances and their applications. Karolinum, Prague] for testing simple hypotheses of goodness of fit and homogeneity. The asymptotic null distribution of test statistics is established and coincides with the distribution of infinite quadratic form of independent standard normal random variables. A construction of multivariate free-of-distribution homogeneity test is considered. The power of proposed criteria is compared with classical tests using Monte-Carlo simulations.