Non-binary neighbor balance circular designs for v=2n and λ=2

Neighbor balance designs were first introduced by Rees (1967) in circular blocks for the use in serological research. Subsequently several researchers have defined the neighbor designs in different ways. In this paper, neighbor balance circular designs for (k≤v) block size are constructed for even number of treatments i.e. v=2n. No such series of designs is known in literature. Two theorems are developed for circular designs. Theorem 1 gives the non-binary circular blocks, whereas Theorem 2 generates binary circular blocks when n≤4 and non-binary blocks for n>4. In suggested designs no treatment is ever a neighbor of itself. Blocks are constructed in such a way that each treatment is a right and left neighbor of every other treatment for a fixed number of times say λ. Sizes of initial circular blocks are not same. One main guiding principle for such designs is to ensure economy in material use.     

Split-plot designs with mirror image pairs as sub-plots

In this article we investigate two-level split-plot designs where the sub-plots consist of only two mirror image trials. Assuming third and higher order interactions negligible, we show that these designs divide the estimated effects into two orthogonal sub-spaces, separating sub-plot main effects and sub-plot by whole-plot interactions from the rest. Further we show how to construct split-plot designs of projectivity P≥3. We also introduce a new class of split-plot designs with mirror image pairs constructed from non-geometric Plackett-Burman designs. The design properties of such designs are very appealing with effects of major interest free from full aliasing assuming that 3rd and higher order interactions are negligible.     

Two-level minimum aberration designs in N =2 (mod 4) runs

For two-level factorials, we consider designs in N=2 (mod 4) runs as obtained by adding two runs, with a certain coincidence pattern, to an orthogonal array of strength two. These designs are known to be optimal main effect plans in a very broad sense in the absence of interactions. Among them, we explore the ones having minimum aberration, with a view to ensuring maximum model robustness even when interactions are possibly present. This is done by sequentially minimizing a measure of the bias caused by interactions of successively higher orders.     

Some d-optimal weighing designs for n≡ (mod 4)

A number of D-optimal weighing designs are constructed with the help of block matrices. The D-optimal designs (n,k,s)=(19,13,10), (19,14,7), (19,14,8), (19,15,7), (19,15,8), (19,17,6), (19,18,6), (23,16,8), (23,17,8), (23,18,8), (4n?1,2n+3,(3n+4)/2), (4n?1,2n+4,n+3), (4n?1,2n+4,n+2) where n≡0 mod 4 and a skew H_n exists, (31,24,8), (31,25,8) and many others are constructed. A computer routine leading to locally D-optimal designs is presented.     

Results for two-level fractional factorial designs of resolution IV or more

The main theorem of this paper shows that foldover designs are the only (regular or nonregular) two-level factorial designs of resolution IV (strength 3) or more for n   runs and n/3?m?n/2$n/3?m?n/2$ factors. This theorem is a generalization of a coding theory result of Davydov and Tombak [1990. Quasiperfect linear binary codes with distance 4 and complete caps in projective geometry. Problems Inform. Transmission 25, 265–275] which, under translation, effectively states that foldover (or even) designs are the only regular two-level factorial designs of resolution IV or more for n   runs and 5n/16?m?n/2$5n/16?m?n/2$ factors. This paper also contains other theorems including an alternative proof of Davydov and Tombak's result.     

Weakly resolvable IV.3 search designs for the pn factorial experiment

A series of weakly resolvable search designs for the pⁿ factorial experiment is given for which the mean and all main effects are estimable in the presence of any number of two-factor interactions and for which any combination of three or fewer pairs of factors that interact may be detected. The designs have N = p(p–1)n+p runs except in one case where additional runs are required for detection and one case where $\text{(p?1)}\text{2}$ additional runs are needed to estimate all (p–1)² degrees of freedom for each pair of detected interactions. The detection procedure is simple enough that computations can be carried out with hand calculations.     

Projective (2n,n,λ,1)-designs

A projective (2n,n,λ,1)-design is a set $\text{D}$ of n element subsets (called blocks) of a 2n-element set V having the properties that each element of V is a member of λ blocks and every two blocks have a non-empty intersection. This paper establishes existence and non-existence results for various projective (2n,n,λ,1)-designs and their subdesigns.     

The A-optimal non-saturated weighing designs for n = 15 observations

The problem of constructing A-optimal weighing and first order fractional factorial designs for n ≡ 3 mod 4 observations is considered. The non-existence of the weighing design matrices for n = 15 observations and k = 13, 14 factors, for which the corresponding information matrices have inverses with minimum trace, is proved. These designs are the first non-saturated cases (k < n) in which the unattainability of Sathe and Shenoy's (1989) lower bound on A-optimality is shown. Using an algorithm proposed in Farmakis (1991) we construct 15 × k (+1, −1)-matrices for k = 13, 14 and we prove their A-optimality using the improved (higher) lower bounds on A-optimality established by Chadjiconstantinidis and Kounias (1994). Also the A-optimal designs for n = 15, k ⩽ 12 are given.     

Indicator function and complex coding for mixed fractional factorial designs

In a general fractional factorial design, the n levels of a factor are coded by the nth roots of the unity. This device allows a full generalization to mixed-level designs of the theory of the polynomial indicator function which has already been introduced for two-level designs in a joint paper with Fontana. The properties of orthogonal arrays and regular fractions are discussed.     

Optimal partially replicated parallel-flats designs for 2×3 mixed factorial experiments

Augmenting additional repeated runs to an unreplicated factorial design provides an economical scheme of obtaining an unbiased estimate for the error variance based on pure replicates. The augmented partially replicated design usually performs satisfactorily in identifying truly active effects regardless of whether the effect sparsity principle holds. Liao and Chai (2009) proposed a set of sufficient conditions for a partially replicated two-level design to be D-optimal over the class of parallel-flats designs. In this article, we generalize their result to the 2^n₁×3^n₂ mixed factorial under D-, A- and E-optimality, and include the 2ⁿ and 3ⁿ symmetric factorials as special cases. In addition, some examples are given to illustrate the main results.     

On the construction of orthogonal F-squares of order n from an orthogonal array (n, k, s, 2) and an OL(s, t) set

Complete sets of orthogonal F-squares of order n = s^p, where g is a prime or prime power and p is a positive integer have been constructed by Hedayat, Raghavarao, and Seiden (1975). Federer (1977) has constructed complete sets of orthogonal F-squares of order n = 4t, where t is a positive integer. We give a general procedure for constructing orthogonal F-squares of order n from an orthogonal array (n, k, s, 2) and an OL(s, t) set, where n is not necessarily a prime or prime power. In particular, we show how to construct sets of orthogonal F-squares of order n = 2s^p, where s is a prime or prime power and p is a positive integer. These sets are shown to be near complete and approach complete sets as s and/or p become large. We have also shown how to construct orthogonal arrays by these methods. In addition, the best upper bound on the number t of orthogonal F(n, λ₁), F(n, λ₂), …, F(n, λ₁) squares is given.     

Statistical properties of Rechtschaffner designs

Rechtschaffner designs are saturated designs of resolution V   in which main effects and two-factor interactions are estimable if three-factor and higher order interactions are negligible. Statistical properties of Rechtschaffner designs are studied in this paper. Best linear unbiased estimators of main effects and two-factor interactions are given explicitly and asymptotic properties of correlations between these estimators are studied as well. It is shown that designs recommended by Rechtschaffner [1967. Saturated fractions of 2ⁿ$2^n$ and 3ⁿ$3^n$ factorial designs, Technometrics 9, 569–576] are not only A-optimal but also D-optimal. Comparisons of Rechtschaffner designs with other A- and D-optimal designs of resolution V are also discussed.     

On the use of partial confounding for the construction of alternative regular two-level blocked fractional factorial designs

In this paper, we consider experimental situations in which a regular fractional factorial design is to be used to study the effects of m two-level factors using n=2^m−k experimental units arranged in 2^p blocks of size 2^m−k−p. In such situations, two-factor interactions are often confounded with blocks and complete information is lost on these two-factor interactions. Here we consider the use of the foldover technique in conjunction with combining designs having different blocking schemes to produce alternative partially confounded blocked fractional factorial designs that have more estimable two-factor interactions or a higher estimation capacity or both than their traditional counterparts.     

THE USE OF A CLASS OF FOLDOVER DESIGNS AS SEARCH DESIGNS

It is shown that members of a class of two-level nonorthogonal resolution IV designs with n factors are strongly resolvable search designs when k, the maximum number of two-factor interactions thought possible, equals one; weakly resolvable when k = 2 except when the number of factors is 6; and may not be weakly resolvable when k≥ 3.     

Serial P-values

When a collection of hypotheses is to be tested it is necessary to maintain a bound on the simultaneous Type I error rate. Serial P-values are used to define a serial test that does provide such a bound. Moreover, serial P-values are meaningful in the context of multiple tests, with or without the ‘rejection-confirmation’ decisions. The method is particularly suited to the analysis of unbalanced data, especially contingency tables.     

Isomorphism check in fractional factorial designs via letter interaction pattern matrix

Two fractional factorial designs are considered isomorphic if one can be obtained from the other by relabeling the factors, reordering the runs, and/or switching the levels of factors. To identify the isomorphism of two designs is known as an NP hard problem. In this paper, we propose a three-dimensional matrix named the letter interaction pattern matrix (LIPM) to characterize the information contained in the defining contrast subgroup of a regular two-level design. We first show that an LIPM could uniquely determine a design under isomorphism and then propose a set of principles to rearrange an LIPM to a standard form. In this way, we can significantly reduce the computational complexity in isomorphism check, which could only take O(2^p)+O(3k³)+O(2^k) operations to check two 2^k−p designs in the worst case. We also find a sufficient condition for two designs being isomorphic to each other, which is very simple and easy to use. In the end, we list some designs with the maximum numbers of clear or strongly clear two-factor interactions which were not found before.     

A formula for P(bi≤Ri≤ai, 1≤i≤m) under a general class of alternatives

Let X_i≤?≤X_m and Y_i≤?≤Y_n be two sets of independent order statistics from continous distributions with distribution functions F and G respectively. Let R_i denote the rank of X_i in the combined order sample. Steck (1980) has found an expression for P(b_i≤R_i≤a_i, all i) when F = h(G), h being the incomplete beta function with parameters (α,β?α+1). An alternative expression for the same probability is obtained which is computationally a substantial improvement on Steck's result.     

Construction of Efficient Multi-Level k-Circulant Supersaturated Designs

This article proposes an algorithm to construct efficient balanced multi-level k-circulant supersaturated designs with m factors and n runs. The algorithm generates efficient balanced multi-level k-circulant supersaturated designs very fast. Using the proposed algorithm many balanced multi-level supersaturated designs are constructed and cataloged. A list of many optimal and near optimal, multi-level supersaturated designs is also provided for m ≤ 60 and number of levels (q) ≤10. The algorithm can be used to generate two-level k-circulant supersaturated designs also and some large optimal two-level supersaturated designs are presented. An upper bound to the number of factors in a balanced multi-level supersaturated design such that no two columns are fully aliased is also provided.     

Optimality aspects of 3-concurrence most balanced designs

Takcuchi (1961,1963) established E-optimality of Group Divisible Designs (GDDs) with λ₂=λ₁+1. Much later, Cheng (1980) and Jacroux (1980,1983) demonstrated E-optimality property of the GDDs with n=2,λ₁=λ₂+1 or with m=2,λ₂=λ₁+2. The purpose of this paper is to provide a unified approach for identifying certain classes of designs as E-optimal. In the process, we come up with a complete characterization of all E-optimal designs attaining a specific bound for the smallest non-zero eigenvalue of the underlying C-matrices. This establishes E-optimality of a class of 3-concurrence most balanced designs with suitable intra- and inter-group balancing. We also discuss the MV-optimality aspect of such designs.     

2<Superscript><Emphasis Type="Italic">m</Emphasis></Superscript>4<Superscript>1</Superscript> designs with minimum aberration or weak minimum aberration

For measuring the goodness of 2 ^m 4¹ designs, Wu and Zhang (1993) proposed the minimum aberration (MA) criterion. MA 2 ^m 4¹ designs have been constructed using the idea of complementary designs when the number of two-level factors, m, exceeds n/2, where n is the total number of runs. In this paper, the structures of MA 2 ^m 4¹ designs are obtained when m>5n/16. Based on these structures, some methods are developed for constructing MA 2 ^m 4¹ designs for 5n/16<m<n/2 as well as for n/2≤m<n. When m≤5n/16, there is no general method for constructing MA 2 ^m 4¹ designs. In this case, we obtain lower bounds for A ₃₀ and A ₃₁, where A ₃₀ and A ₃₁ are the numbers of type 0 and type 1 words with length three respectively. And a method for constructing weak minimum aberration (WMA) 2 ^m 4¹ designs (A ₃₀ and A ₃₁ achieving the lower bounds) is demonstrated. Some MA or WMA 2 ^m 4¹ designs with 32 or 64 runs are tabulated for practical use, which supplement the tables in Wu and Zhang (1993), Zhang and Shao (2001) and Mukerjee and Wu (2001).