Improving survey-weighted least squares regression

The weighted least squares (WLS) estimator is often employed in linear regression using complex survey data to deal with the bias in ordinary least squares (OLS) arising from informative sampling. In this paper a 'quasi-Aitken WLS' (QWLS) estimator is proposed. QWLS modifies WLS in the same way that Cragg's quasi-Aitken estimator modifies OLS. It weights by the usual inverse sample inclusion probability weights multiplied by a parameterized function of covariates, where the parameters are chosen to minimize a variance criterion. The resulting estimator is consistent for the superpopulation regression coefficient under fairly mild conditions and has a smaller asymptotic variance than WLS.     

Model averaging procedure for partially linear single-index models

This paper is concerned with model selection and model averaging procedures for partially linear single-index models. The profile least squares procedure is employed to estimate regression coefficients for the full model and submodels. We show that the estimators for submodels are asymptotically normal. Based on the asymptotic distribution of the estimators, we derive the focused information criterion (FIC), formulate the frequentist model average (FMA) estimators and construct proper confidence intervals for FMA estimators and FIC estimator, a special case of FMA estimators. Monte Carlo studies are performed to demonstrate the superiority of the proposed method over the full model, and over models chosen by AIC or BIC in terms of coverage probability and mean squared error. Our approach is further applied to real data from a male fertility study to explore potential factors related to sperm concentration and estimate the relationship between sperm concentration and monobutyl phthalate.     

Estimation in large cross random-effect models by data augmentation

Estimation in mixed linear models is, in general, computationally demanding, since applied problems may involve extensive data sets and large numbers of random effects. Existing computer algorithms are slow and/or require large amounts of memory. These problems are compounded in generalized linear mixed models for categorical data, since even approximate methods involve fitting of a linear mixed model within steps of an iteratively reweighted least squares algorithm. Only in models in which the random effects are hierarchically nested can the computations for fitting these models to large data sets be carried out rapidly. We describe a data augmentation approach to these computational difficulties in which we repeatedly fit an overlapping series of submodels, incorporating the missing terms in each submodel as 'offsets'. The submodels are chosen so that they have a nested random-effect structure, thus allowing maximum exploitation of the computational efficiency which is available in this case. Examples of the use of the algorithm for both metric and discrete responses are discussed, all calculations being carried out using macros within the MLwiN program.     

Median regression analysis from data with left and right censored observations

Median regression models provide a robust alternative to regression based on the mean. We propose a methodology for fitting a median regression model from data with both left and right censored observations, in which the left censoring variable is always observed. First we set up an adjusted least absolute deviation estimating function using the inverse censoring weighted approach, whose solution specifies the estimator. We derive the consistency and asymptotic normality of the proposed estimator and describe the inference procedure for the regression parameter. Finally, we check the finite sample performance of the proposed procedure through simulation.     

Small area estimation using unmatched sampling and linking models

The authors use a hierarchical Bayes approach to area level unmatched sampling and Unking models for small area estimation. Empirically they compare inferences under unmatched models with those obtained under the customary matched sampling and linking models. They apply the proposed method to Canadian census undercoverage estimation, developing a full hierarchical Bayes approach using Markov Chain Monte Carlo sampling methods. They show that the method can provide efficient model‐based estimates. They use posterior predictive distributions to assess model fit.     

Estimation of causal continuous‐time autoregressive moving average random fields

We estimate model parameters of Lévy‐driven causal continuous‐time autoregressive moving average random fields by fitting the empirical variogram to the theoretical counterpart using a weighted least squares (WLS) approach. Subsequent to deriving asymptotic results for the variogram estimator, we show strong consistency and asymptotic normality of the parameter estimator. Furthermore, we conduct a simulation study to assess the quality of the WLS estimator for finite samples. For the simulation, we utilize numerical approximation schemes based on truncation and discretization of stochastic integrals and we analyze the associated simulation errors in detail. Finally, we apply our results to real data of the cosmic microwave background.     

Weighted likelihood latent class linear regression

Statistical Methods & Applications - A weighted likelihood approach for robust fitting of a finite mixture of linear regression models is proposed. An EM type algorithm and its variant based on...     

Weighting Method for a Linear Mixed Model

Maximum likelihood is a widely used estimation method in statistics. This method is model dependent and as such is criticized as being non robust. In this article, we consider using weighted likelihood method to make robust inferences for linear mixed models where weights are determined at both the subject level and the observation level. This approach is appropriate for problems where maximum likelihood is the basic fitting technique, but a subset of data points is discrepant with the model. It allows us to reduce the impact of outliers without complicating the basic linear mixed model with normally distributed random effects and errors. The weighted likelihood estimators are shown to be robust and asymptotically normal. Our simulation study demonstrates that the weighted estimates are much better than the unweighted ones when a subset of data points is far away from the rest. Its application to the analysis of deglutition apnea duration in normal swallows shows that the differences between the weighted and unweighted estimates are due to large amount of outliers in the data set.     

Modeling probability density through ultraspherical polynomial transformations

We present a method for fitting parametric probability density models using an integrated square error criterion on a continuum of weighted Lebesgue spaces formed by ultraspherical polynomials. This approach is inherently suitable for creating mixture model representations of complex distributions and allows fully autonomous cluster analysis of high-dimensional datasets. The method is also suitable for extremely large sets, allowing post facto model selection and analysis even in the absence of the original data. Furthermore, the fitting procedure only requires the parametric model to be pointwise evaluable, making it trivial to fit user-defined models through a generic algorithm.     

Back propagation neural networks and multiple regressions in the case of heteroskedasticity

This paper compares the performance between regression analysis and a clustering based neural network approach when the data deviates from the homoscedasticity assumption of regression. Heteroskedasticity is a problem that arises in linear regression due to the unequal error variances. One of the methods to deal heteroskedasticity in classical regression theory is weighted least-square regression (WLS). In order to deal the problem of heteroskedasticity, backpropagation neural network is applied. In this context, an algorithm is proposed which is based on robust estimates of location and dispersion matrix that helps in preserving the error assumption of the linear regression. Analysis is carried out with appropriate designs using simulated data and the results are presented.     

A method for combining inference across related nonparametric Bayesian models

Summary.  We consider the problem of combining inference in related nonparametric Bayes models. Analogous to parametric hierarchical models, the hierarchical extension formalizes borrowing strength across the related submodels. In the nonparametric context, modelling is complicated by the fact that the random quantities over which we define the hierarchy are infinite dimensional. We discuss a formal definition of such a hierarchical model. The approach includes a regression at the level of the nonparametric model. For the special case of Dirichlet process mixtures, we develop a Markov chain Monte Carlo scheme to allow efficient implementation of full posterior inference in the given model.     

The Cox–Aalen model for left-truncated and right-censored data

We analyze left-truncated and right-censored (LTRC) data using an additive-multiplicative Cox–Aalen model proposed by Scheike and Zhang (2002), which extends the Cox regression model as well as the additive Aalen model. Based on the conditional likelihood function, we derive the weighted least-squared (WLS) estimators for the regression parameters and cumulative intensity functions of the model. The estimators are shown to be consistent and asymptotically normal. A simulation study is conducted to investigate the performance of the proposed estimators.     

Lines through the origin—is NO INT the answer?

The fitting of a straight line that must pass through (0, 0) is a frequently encountered application of linear regression. Many computer packages provide a least-squares option sometimes identified as NO INT, or even NOINT, or as ‘suppressing the intercept’. Often these procedures are invalid or do not correspond to the most suitable model. This paper questions the least-squares-line approach and suggests some alternatives. Two measures are proposed for comparing the fit of alternative models.     

Bayesian estimation and case influence diagnostics for the zero-inflated negative binomial regression model

In recent years, there has been considerable interest in regression models based on zero-inflated distributions. These models are commonly encountered in many disciplines, such as medicine, public health, and environmental sciences, among others. The zero-inflated Poisson (ZIP) model has been typically considered for these types of problems. However, the ZIP model can fail if the non-zero counts are overdispersed in relation to the Poisson distribution, hence the zero-inflated negative binomial (ZINB) model may be more appropriate. In this paper, we present a Bayesian approach for fitting the ZINB regression model. This model considers that an observed zero may come from a point mass distribution at zero or from the negative binomial model. The likelihood function is utilized to compute not only some Bayesian model selection measures, but also to develop Bayesian case-deletion influence diagnostics based on q-divergence measures. The approach can be easily implemented using standard Bayesian software, such as WinBUGS. The performance of the proposed method is evaluated with a simulation study. Further, a real data set is analyzed, where we show that ZINB regression models seems to fit the data better than the Poisson counterpart.     

Case-cohort analysis with semiparametric transformation models

Semiparametric transformation models provide flexible regression models for survival analysis, including the Cox proportional hazards and the proportional odds models as special cases. We consider the application of semiparametric transformation models in case-cohort studies, where the covariate data are observed only on cases and on a subcohort randomly sampled from the full cohort. We first propose an approximate profile likelihood approach with full-cohort data, which amounts to the pseudo-partial likelihood approach of Zucker [2005. A pseudo-partial likelihood method for semiparametric survival regression with covariate errors. J. Amer. Statist. Assoc. 100, 1264–1277]. Simulation results show that our proposal is almost as efficient as the nonparametric maximum likelihood estimator. We then extend this approach to the case-cohort design, applying the Horvitz–Thompson weighting method to the estimating equations from the approximated profile likelihood. Two levels of weights can be utilized to achieve unbiasedness and to gain efficiency. The resulting estimator has a closed-form asymptotic covariance matrix, and is found in simulations to be substantially more efficient than the estimator based on martingale estimating equations. The extension to left-truncated data will be discussed. We illustrate the proposed method on data from a cardiovascular risk factor study conducted in Taiwan.     

The probabilistic reduction approach to specifying multinomial logistic regression models in health outcomes research

The paper provides a novel application of the probabilistic reduction (PR) approach to the analysis of multi-categorical outcomes. The PR approach, which systematically takes account of heterogeneity and functional form concerns, can improve the specification of binary regression models. However, its utility for systematically enriching the specification of and inference from models of multi-categorical outcomes has not been examined, while multinomial logistic regression models are commonly used for inference and, increasingly, prediction. Following a theoretical derivation of the PR-based multinomial logistic model (MLM), we compare functional specification and marginal effects from a traditional specification and a PR-based specification in a model of post-stroke hospital discharge disposition and find that the traditional MLM is misspecified. Results suggest that the impact on the reliability of substantive inferences from a misspecified model may be significant, even when model fit statistics do not suggest a strong lack of fit compared with a properly specified model using the PR approach. We identify situations under which a PR-based MLM specification can be advantageous to the applied researcher.     

Bayesian MARS

A Bayesian approach to multivariate adaptive regression spline (MARS) fitting (Friedman, 1991) is proposed. This takes the form of a probability distribution over the space of possible MARS models which is explored using reversible jump Markov chain Monte Carlo methods (Green, 1995). The generated sample of MARS models produced is shown to have good predictive power when averaged and allows easy interpretation of the relative importance of predictors to the overall fit.     

On the robustness of weighted methods for fitting models to case–control data

Summary. We compare the robustness under model misspecification of two approaches to fitting logistic regression models with unmatched case–control data. One is the standard survey approach based on weighted versions of population estimating equations. The other is the likelihood-based approach that is standard in medical applications. The conventional view is that the (less efficient) survey-weighted approach leads to greater robustness. We conclude that this view is not always justified.     

A bayesian wls approach to generalized linear models

We use a Bayesian approach to fitting a linear regression model to transformations of the natural parameter for the exponential class of distributions. The usual Bayesian approach is to assume that a linear model exactly describes the relationship among the natural parameters. We assume only that a linear model is approximately in force. We approximate the theta-links by using a linear model obtained by minimizing the posterior expectation of a loss function.While some posterior results can be obtained analytically considerable generality follows from an exact Monte Carlo method for obtaining random samples of parameter values or functions of parameter values from their respective posterior distributions. The approach that is presented is justified for small samples, requires only one-dimensional numerical integrations, and allows for the use of regression matrices with less than full column rank. Two numerical examples are provided.     

Semiparametric lower bounds for tail index estimation

We consider estimation of the tail index parameter from i.i.d. observations in Pareto and Weibull type models, using a local and asymptotic approach. The slowly varying function describing the non-tail behavior of the distribution is considered as an infinite dimensional nuisance parameter. Without further regularity conditions, we derive a local asymptotic normality (LAN) result for suitably chosen parametric submodels of the full semiparametric model. From this result, we immediately obtain the optimal rate of convergence of tail index parameter estimators for more specific models previously studied. On top of the optimal rate of convergence, our LAN result also gives the minimal limiting variance of estimators (regular for our parametric model) through the convolution theorem. We show that the classical Hill estimator is regular for the submodels introduced with limiting variance equal to the induced convolution theorem bound. We also discuss the Weibull model in this respect.