共查询到20条相似文献,搜索用时 31 毫秒
1.
The Significance Analysis of Microarrays (SAM; Tusher et al., 2001) method is widely used in analyzing gene expression data while controlling the FDR by using resampling-based procedure in the microarray setting. One of the main components of the SAM procedure is the adjustment of the test statistic. The introduction of the fudge factor to the test statistic aims at deflating the large value of test statistics due to the small standard error of gene-expression. Lin et al. (2008) pointed out that the fudge factor does not effectively improve the power and the control of the FDR as compared to the SAM procedure without the fudge factor in the presence of small variance genes. Motivated by the simulation results presented in Lin et al. (2008), in this article, we extend our study to compare several methods for choosing the fudge factor in the modified t-type test statistics and use simulation studies to investigate the power and the control of the FDR of the considered methods. 相似文献
2.
AbstractIn this article, we improvise Singh and Grewal (2013) and Hussain et al. (2016) techniques by introducing a new two-stage randomization response process. Using the proposed new technique, we achieve better efficiency and increasing protection of privacy of respondents than the Kuk (1990), Singh and Grewal (2013) and Hussain et al. (2016) models. The relative efficiency and protection of the respondents of the proposed two-stage randomization device have been investigated through simulation study, and the situations are reported where the proposed estimator performs better than its competitors. The SAS code used to investigate the performance of the proposed strategy are also provided. 相似文献
3.
Feng-Shou Ko 《统计学通讯:理论与方法》2013,42(15):2681-2698
A proposed method based on frailty models is used to identify longitudinal biomarkers or surrogates for a multivariate survival. This method is an extention of earlier models by Wulfsohn and Tsiatis (1997) and Song et al. (2002). In this article, similar to Henderson et al. (2002), a joint likelihood function combines the likelihood functions of the longitudinal biomarkers and the multivariate survival times. We use simulations to explore how the number of individuals, the number of time points per individual and the functional form of the random effects from the longitudianl biomarkers influence the power to detect the association of a longitudinal biomarker and the multivariate survival time. The proposed method is illustrate by using the gastric cancer data. 相似文献
4.
Gadre and Rattihalli [5] have introduced the Modified Group Runs (MGR) control chart to identify the increases in fraction non-conforming and to detect shifts in the process mean. The MGR chart reduces the out-of-control average time-to-signal (ATS), as compared with most of the well-known control charts. In this article, we develop the Side Sensitive Modified Group Runs (SSMGR) chart to detect shifts in the process mean. With the help of numerical examples, it is illustrated that the SSMGR chart performs better than the Shewhart's X¯ chart, the synthetic chart [12], the Group Runs chart [4], the Side Sensitive Group Runs chart [6], as well as the MGR chart [5]. In some situations it is also superior to the Cumulative Sum chart p9] and the exponentially weighed moving average chart [10]. In the steady state also, its performance is better than the above charts. 相似文献
5.
Suchandan Kayal 《统计学通讯:理论与方法》2018,47(20):4938-4957
Several probability distributions such as power-Pareto distribution (see Gilchrist 2000 and Hankin and Lee 2006), various forms of lambda distributions (see Ramberg and Schmeiser 1974 and Freimer et al. 1988), Govindarajulu distribution (see Nair, Sankaran, and Vineshkumar 2012), etc., do not have manageable distribution functions, though they have tractable quantile functions. Hence, analytical study of the properties of Chernoff distance of two random variables associated with these distributions via traditional distribution function-based tool becomes difficult. To make this simple, in this paper, we introduce quantile-based Chernoff distance for (left or right) truncated random variables and study its various properties. Some useful bounds as well as characterization results are obtained. 相似文献
6.
Pao-Sheng Shen 《统计学通讯:模拟与计算》2013,42(3):603-612
In this article, we consider the M-estimators for the linear regression model when both response and covariate variables are subject to double censoring. The proposed estimators are constructed as some functional of three types of estimators for a bivariate survival distribution. The first two estimators are the generalizations of the Campbell and Földes (1982) and Dabrowska (1988) estimators proposed by Shen (2009). The third estimator is the generalization of the Prentice and Cai (1992) estimator. The consistency of the proposed M-estimators is established. A simulation study is conducted to investigate the performance of the proposed estimators. Furthermore, the simple bootstrap methods are used to estimate standard deviations and construct interval estimators. 相似文献
7.
We consider non-parametric estimation of a continuous cdf of a random vector (X 1, X 2). With bivariate RC data, it is stated in van der Laan (1996, p. 59810, Ann. Statist.), Quale et al. (2006, JASA) etc. that “it is well known that the NPMLE for continuous data is inconsistent (Tsai et al. (1986)).” The claim is based on a result in Tsai et al. (1986, p.1352, Ann. Statist.) that if X 1 is right censored but not X 2, then common ways for defining one NPMLE lead to inconsistency. If X 1 is right censored and X 2 is type I right-censored (which includes the case in Tsai et al.), we present a consistent NPMLE. The result corrects a common misinterpretation of Tsai's example (Tsai et al., 1986, Ann. Statist.). 相似文献
8.
Shesh N. Rai Jianmin Pan Xiaobin Yuan Jianguo Sun Melissa M. Hudson Deo K. Srivastava 《统计学通讯:理论与方法》2013,42(17):3117-3133
New drug discovery in the pediatrics has dramatically improved survival, but with long- term adverse events. This motivates the examination of adverse outcomes such as long-term toxicity in a phase IV trial. An ideal approach to monitor long-term toxicity is to systematically follow the survivors, which is generally not feasible. Instead, cross-sectional surveys are conducted in Hudson et al. (2007), with one of the objectives to estimate the cumulative incidence rates along with specific interest in fixed-term (5 or 10 year) rates. We present inference procedures based on current status data to our motivating example with very interesting findings. 相似文献
9.
The traditional exponentially weighted moving average (EWMA) chart is one of the most popular control charts used in practice today. The in-control robustness is the key to the proper design and implementation of any control chart, lack of which can render its out-of-control shift detection capability almost meaningless. To this end, Borror et al. [5] studied the performance of the traditional EWMA chart for the mean for i.i.d. data. We use a more extensive simulation study to further investigate the in-control robustness (to non-normality) of the three different EWMA designs studied by Borror et al. [5]. Our study includes a much wider collection of non-normal distributions including light- and heavy-tailed and symmetric and asymmetric bi-modal as well as the contaminated normal, which is particularly useful to study the effects of outliers. Also, we consider two separate cases: (i) when the process mean and standard deviation are both known and (ii) when they are both unknown and estimated from an in-control Phase I sample. In addition, unlike in the study done by Borror et al. [5], the average run-length (ARL) is not used as the sole performance measure in our study, we consider the standard deviation of the run-length (SDRL), the median run-length (MDRL), and the first and the third quartiles as well as the first and the 99th percentiles of the in-control run-length distribution for a better overall assessment of the traditional EWMA chart's in-control performance. Our findings sound a cautionary note to the (over) use of the EWMA chart in practice, at least with some types of non-normal data. A summary and recommendations are provided. 相似文献
10.
Hafiz M. R. Khan 《统计学通讯:理论与方法》2013,42(24):4427-4438
The purpose of this article is to investigate the predictive inference for responses from the location parameter mean as well as from the median given a doubly censored sample from the two-parameter Rayleigh model. The predictive results by Khan et al. (2010) are used to obtain the predictive inference for responses from the median, where Khan et al. (2010) obtained the future estimates from the mean. A numerical example representing 66 liver cancer patients is used for predictive analysis. It is concluded that the predictive inference from the median gives precise results as compared with the location parameter mean. 相似文献
11.
AbstractWhen the mixed chart proposed by Aslam et al. (2015) is in use, the sample items are classified as defective or not defective and, depending on the number of defectives, the quality characteristic X of the sample items are also measured. In this case, an Xbar chart decides the state of the process. The previous conforming/non-conforming classification truncates the X distribution and, because of that, the mathematical development to obtain the ARLs is complex. Aslam et al. (2015) didn’t pay attention to the fact that the X distribution is truncated and, due to that, they obtained incorrect ARLs. 相似文献
12.
Feng-Shou Ko 《统计学通讯:理论与方法》2013,42(18):3222-3237
We introduce a score test to identify longitudinal biomarkers or surrogates for a time to event outcome. This method is an extension of Henderson et al. (2000, 2002). In this article, a score test is based on a joint likelihood function which combines the likelihood functions of the longitudinal biomarkers and the survival times. Henderson et al. (2000, 2002) assumed that the same random effect exists in the longitudinal component and in the Cox model and then they can derive a score test to determine if a longitudinal biomarker is associated with time to an event. We extend this work and our score test is based on a joint likelihood function which allows other random effects to be present in the survival function. Considering heterogeneous baseline hazards in individuals, we use simulations to explore how the factors can influence the power of a score test to detect the association of a longitudinal biomarker and the survival time. These factors include the functional form of the random effects from the longitudinal biomarkers, in the different number of individuals, and time points per individual. We illustrate our method using a prothrombin index as a predictor of survival in liver cirrhosis patients. 相似文献
13.
For the first time, we provide a matrix formula for second-order covariances of maximum likelihood estimates in heteroskedastic generalized linear models, thus generalizing the results of Cordeiro (2004) and Cordeiro et al. (2006) related to the generalized linear models with known and unknown dispersion parameter, respectively. The covariance matrix formula does not involve cumulants of log-likelihood derivatives and can be easily obtained using simple matrix operations. We apply our main result to a simple model. Some simulations show that the second-order covariances can be quite pronounced in small to moderate samples. The usual covariances of the maximum likelihood estimates can be corrected by these second-order covariances. 相似文献
14.
Jiang, Ji, and Xiao (2003) has introduced a quantitative measure known as the ageing intensity function for evaluating the ageing properties of a component/system. In recent years, there has been a great interest on the study of quantile function, an equivalent alternative to the distribution function approach. Unlike the distribution function approach, the quantile method possess some unique properties (see Gilchrist 2000, Nair, Sankaran, and Balakrishnan 2013). Motivated with this, in the present paper we introduce a quantile-based ageing intensity function and study its various ageing properties. We also study some stochastic comparison of random variables based on the proposed measure. 相似文献
15.
Soo Hak Sung 《统计学通讯:理论与方法》2013,42(9):1663-1674
A complete convergence theorem for an array of rowwise independent random variables was established by Sung et al. (2005). This result has been generalized and extended by Kruglov et al. (2006) and Chen et al. (2007). In this article, we extend the results of Sung et al. (2005), Kruglov et al. (2006), and Chen et al. (2007) to an array of dependent random variables satisfying Hoffmann-Jørgensen type inequalities. 相似文献
16.
Jigao Yan 《统计学通讯:理论与方法》2013,42(20):5074-5098
AbstractIn this paper, the complete convergence for maximal weighted sums of extended negatively dependent (END, for short) random variables is investigated. Some sufficient conditions for the complete convergence and some applications to a nonparametric model are provided. The results obtained in the paper generalize and improve the corresponding ones of Wang et al. (2014b) and Shen, Xue, and Wang (2017). 相似文献
17.
N. Unnikrishnan Nair 《统计学通讯:理论与方法》2013,42(2):222-232
Quantile functions are equivalent alternatives to distribution functions in modeling and analysis of statistical data. The present article discusses the role of quantile functions in reliability studies. We present the hazard, mean residual, variance residual, and percentile residual quantile functions, their mutual relationships and expressions for the quantile functions in terms of these functions. Further, some theoretical results relating to the Hankin and Lee (2006) lambda distribution are discussed. 相似文献
18.
Extending the bifurcating autoregressive (BAR) process (cf. Cowan and Staudte, 1986) to multi-casting (multi-splitting) data, Hwang and Choi (2009) introduced multi-casting autoregression (MCAR, for short) defined on multi-casting tree structured data. This article is concerned with the case when the MCAR model is partially specified only through conditional mean and variance without directly imposing autoregressive (AR) structure. The resulting class of models will be referred to as P-MCAR (partially specified MCAR). The P-MCAR considerably enlarges the class of multi-casting models including (as special cases) MCAR, random coefficient MCAR, conditionally heteroscedastic multi-casting models and binomial-thinning processes. Moment structures for this broad P-MCAR class are investigated. Least squares (LS) estimation method is discussed and asymptotic relative efficiency (ARE) of the generalized-LS over ordinary-LS is obtained in a closed form. A simulation study is conducted to illustrate results. 相似文献
19.
Shaowen Wu 《统计学通讯:模拟与计算》2013,42(8):1590-1604
We reinvestigate the empirical problem of lag length selection in unit root tests when using the augmented Dickey–Fuller test based on GLS-detrending. We extend the Ng and Perron (1995) work on this issue by applying the finite sample critical values calculated using the formulae proposed by Cheung and Lai (1995). Unlike Ng and Perron (2001) we find through simulation studies that the method of selecting lag length using the sequential t-test in the ADF regression of GLS-detrended series performs the best in most cases. 相似文献
20.
We propose a class of estimators for the population mean when there are missing data in the data set. Obtaining the mean square error equations of the proposed estimators, we show the conditions where the proposed estimators are more efficient than the sample mean, ratio-type estimators, and the estimators in Singh and Horn (2000) and Singh and Deo (2003) in the case of missing data. These conditions are also supported by a numerical example. 相似文献