Quantile regression for robust estimation and variable selection in partially linear varying-coefficient models

In this paper, we develop a new estimation procedure based on quantile regression for semiparametric partially linear varying-coefficient models. The proposed estimation approach is empirically shown to be much more efficient than the popular least squares estimation method for non-normal error distributions, and almost not lose any efficiency for normal errors. Asymptotic normalities of the proposed estimators for both the parametric and nonparametric parts are established. To achieve sparsity when there exist irrelevant variables in the model, two variable selection procedures based on adaptive penalty are developed to select important parametric covariates as well as significant nonparametric functions. Moreover, both these two variable selection procedures are demonstrated to enjoy the oracle property under some regularity conditions. Some Monte Carlo simulations are conducted to assess the finite sample performance of the proposed estimators, and a real-data example is used to illustrate the application of the proposed methods.     

Bayesian spectral analysis models for quantile regression with Dirichlet process mixtures

This paper presents a Bayesian analysis of partially linear additive models for quantile regression. We develop a semiparametric Bayesian approach to quantile regression models using a spectral representation of the nonparametric regression functions and the Dirichlet process (DP) mixture for error distribution. We also consider Bayesian variable selection procedures for both parametric and nonparametric components in a partially linear additive model structure based on the Bayesian shrinkage priors via a stochastic search algorithm. Based on the proposed Bayesian semiparametric additive quantile regression model referred to as BSAQ, the Bayesian inference is considered for estimation and model selection. For the posterior computation, we design a simple and efficient Gibbs sampler based on a location-scale mixture of exponential and normal distributions for an asymmetric Laplace distribution, which facilitates the commonly used collapsed Gibbs sampling algorithms for the DP mixture models. Additionally, we discuss the asymptotic property of the sempiparametric quantile regression model in terms of consistency of posterior distribution. Simulation studies and real data application examples illustrate the proposed method and compare it with Bayesian quantile regression methods in the literature.     

Adaptive lasso for accelerated hazards models

The important feature of the accelerated hazards (AH) model is that it can capture the gradual effect of treatment. Because of the complexity in its estimation, few discussion has been made on the variable selection of the AH model. The Bayesian non-parametric prior, called the transformed Bernstein polynomial prior, is employed for simultaneously robust estimation and variable selection in sparse AH models. We first introduce a naive lasso-type accelerated hazards model, and later, in order to reduce estimation bias and improve variable selection accuracy, we further consider an adaptive lasso AH model as a direct extension of the naive lasso-type model. Through our simulation studies, we obtain that the adaptive lasso AH model performs better than the lasso-type model with respect to the variable selection and prediction accuracy. We also illustrate the performance of the proposed methods via a brain tumour study.     

NEW EFFICIENT ESTIMATION AND VARIABLE SELECTION METHODS FOR SEMIPARAMETRIC VARYING-COEFFICIENT PARTIALLY LINEAR MODELS

The complexity of semiparametric models poses new challenges to statistical inference and model selection that frequently arise from real applications. In this work, we propose new estimation and variable selection procedures for the semiparametric varying-coefficient partially linear model. We first study quantile regression estimates for the nonparametric varying-coefficient functions and the parametric regression coefficients. To achieve nice efficiency properties, we further develop a semiparametric composite quantile regression procedure. We establish the asymptotic normality of proposed estimators for both the parametric and nonparametric parts and show that the estimators achieve the best convergence rate. Moreover, we show that the proposed method is much more efficient than the least-squares-based method for many non-normal errors and that it only loses a small amount of efficiency for normal errors. In addition, it is shown that the loss in efficiency is at most 11.1% for estimating varying coefficient functions and is no greater than 13.6% for estimating parametric components. To achieve sparsity with high-dimensional covariates, we propose adaptive penalization methods for variable selection in the semiparametric varying-coefficient partially linear model and prove that the methods possess the oracle property. Extensive Monte Carlo simulation studies are conducted to examine the finite-sample performance of the proposed procedures. Finally, we apply the new methods to analyze the plasma beta-carotene level data.     

Variable selection for semiparametric varying coefficient partially linear model based on modal regression with missing data

Abstract

In this article, we focus on the variable selection for semiparametric varying coefficient partially linear model with response missing at random. Variable selection is proposed based on modal regression, where the non parametric functions are approximated by B-spline basis. The proposed procedure uses SCAD penalty to realize variable selection of parametric and nonparametric components simultaneously. Furthermore, we establish the consistency, the sparse property and asymptotic normality of the resulting estimators. The penalty estimation parameters value of the proposed method is calculated by EM algorithm. Simulation studies are carried out to assess the finite sample performance of the proposed variable selection procedure.     

Assessing goodness-of-fit of categorical regression models based on case-control data

Demonstrated equivalence between a categorical regression model based on case‐control data and an I‐sample semiparametric selection bias model leads to a new goodness‐of‐fit test. The proposed test statistic is an extension of an existing Kolmogorov–Smirnov‐type statistic and is the weighted average of the absolute differences between two estimated distribution functions in each response category. The paper establishes an optimal property for the maximum semiparametric likelihood estimator of the parameters in the I‐sample semiparametric selection bias model. It also presents a bootstrap procedure, some simulation results and an analysis of two real datasets.     

Variable selection for semiparametric errors-in-variables regression model with longitudinal data

In this paper, we focus on the variable selection for the semiparametric regression model with longitudinal data when some covariates are measured with errors. A new bias-corrected variable selection procedure is proposed based on the combination of the quadratic inference functions and shrinkage estimations. With appropriate selection of the tuning parameters, we establish the consistency and asymptotic normality of the resulting estimators. Extensive Monte Carlo simulation studies are conducted to examine the finite sample performance of the proposed variable selection procedure. We further illustrate the proposed procedure with an application.     

Semiparametric Analysis of Isotonic Errors-in-Variables Regression Models with Missing Response

This article is concerned with the estimation problem in the semiparametric isotonic regression model when the covariates are measured with additive errors and the response is missing at random. An inverse marginal probability weighted imputation approach is developed to estimate the regression parameters and a least-square approach under monotone constraint is employed to estimate the functional component. We show that the proposed estimator of the regression parameter is root-n consistent and asymptotically normal and the isotonic estimator of the functional component, at a fixed point, is cubic root-n consistent. A simulation study is conducted to examine the finite-sample properties of the proposed estimators. A data set is used to demonstrate the proposed approach.     

Efficient Estimation of the Partly Linear Additive Hazards Model with Current Status Data

This paper focuses on efficient estimation, optimal rates of convergence and effective algorithms in the partly linear additive hazards regression model with current status data. We use polynomial splines to estimate both cumulative baseline hazard function with monotonicity constraint and nonparametric regression functions with no such constraint. We propose a simultaneous sieve maximum likelihood estimation for regression parameters and nuisance parameters and show that the resultant estimator of regression parameter vector is asymptotically normal and achieves the semiparametric information bound. In addition, we show that rates of convergence for the estimators of nonparametric functions are optimal. We implement the proposed estimation through a backfitting algorithm on generalized linear models. We conduct simulation studies to examine the finite‐sample performance of the proposed estimation method and present an analysis of renal function recovery data for illustration.     

Bayesian variable selection approach to a Bernstein polynomial regression model with stochastic constraints

This paper provides a Bayesian estimation procedure for monotone regression models incorporating the monotone trend constraint subject to uncertainty. For monotone regression modeling with stochastic restrictions, we propose a Bayesian Bernstein polynomial regression model using two-stage hierarchical prior distributions based on a family of rectangle-screened multivariate Gaussian distributions extended from the work of Gurtis and Ghosh [7 S.M. Curtis and S.K. Ghosh, A variable selection approach to monotonic regression with Bernstein polynomials, J. Appl. Stat. 38 (2011), pp. 961–976. doi: 10.1080/02664761003692423[Taylor &; Francis Online], [Web of Science ®] , [Google Scholar]]. This approach reflects the uncertainty about the prior constraint, and thus proposes a regression model subject to monotone restriction with uncertainty. Based on the proposed model, we derive the posterior distributions for unknown parameters and present numerical schemes to generate posterior samples. We show the empirical performance of the proposed model based on synthetic data and real data applications and compare the performance to the Bernstein polynomial regression model of Curtis and Ghosh [7 S.M. Curtis and S.K. Ghosh, A variable selection approach to monotonic regression with Bernstein polynomials, J. Appl. Stat. 38 (2011), pp. 961–976. doi: 10.1080/02664761003692423[Taylor &; Francis Online], [Web of Science ®] , [Google Scholar]] for the shape restriction with certainty. We illustrate the effectiveness of our proposed method that incorporates the uncertainty of the monotone trend and automatically adapts the regression function to the monotonicity, through empirical analysis with synthetic data and real data applications.     

Variable selection for semiparametric regression models with iterated penalization

Semiparametric regression models with multiple covariates are commonly encountered. When there are covariates not associated with response variable, variable selection may lead to sparser models, more lucid interpretations and more accurate estimation. In this study, we adopt a sieve approach for the estimation of nonparametric covariate effects in semiparametric regression models. We adopt a two-step iterated penalization approach for variable selection. In the first step, a mixture of the Lasso and group Lasso penalties are employed to conduct the first-round variable selection and obtain the initial estimate. In the second step, a mixture of the weighted Lasso and weighted group Lasso penalties, with weights constructed using the initial estimate, are employed for variable selection. We show that the proposed iterated approach has the variable selection consistency property, even when number of unknown parameters diverges with sample size. Numerical studies, including simulation and analysis of a diabetes dataset, show satisfactory performance of the proposed approach.     

Bayesian variable selection with strong heredity constraints

In this paper, we propose a Bayesian variable selection method for linear regression models with high-order interactions. Our method automatically enforces the heredity constraint, that is, a higher order interaction term can exist in the model only if both of its parent terms are in the model. Based on the stochastic search variable selection George and McCulloch (1993), we propose a novel hierarchical prior that fully considers the heredity constraint and controls the degree of sparsity simultaneously. We develop a Markov chain Monte Carlo (MCMC) algorithm to explore the model space efficiently while accounting for the heredity constraint by modifying the shotgun stochastic search algorithm Hans et al. (2007). The performance of the new model is demonstrated through comparisons with other methods. Numerical studies on both real data analysis and simulations show that our new method tends to find relevant variable more effectively when higher order interaction terms are considered.     

Regression analysis of informative current status data with the semiparametric linear transformation model

Many methods have been developed in the literature for regression analysis of current status data with noninformative censoring and also some approaches have been proposed for semiparametric regression analysis of current status data with informative censoring. However, the existing approaches for the latter situation are mainly on specific models such as the proportional hazards model and the additive hazard model. Corresponding to this, in this paper, we consider a general class of semiparametric linear transformation models and develop a sieve maximum likelihood estimation approach for the inference. In the method, the copula model is employed to describe the informative censoring or relationship between the failure time of interest and the censoring time, and Bernstein polynomials are used to approximate the nonparametric functions involved. The asymptotic consistency and normality of the proposed estimators are established, and an extensive simulation study is conducted and indicates that the proposed approach works well for practical situations. In addition, an illustrative example is provided.     

Bias-corrected maximum semiparametric likelihood estimation under logistic regression models based on case–control data

We consider the corrective approach (Theoretical Statistics, Chapman & Hall, London, 1974, p. 310) and preventive approach (Biometrica 80 (1993) 27) to bias reduction of maximum likelihood estimators under the logistic regression model based on case–control data. The proposed bias-corrected maximum likelihood estimators are based on the semiparametric profile log likelihood function under a two-sample semiparametric model, which is equivalent to the assumed logistic regression model. We show that the prospective and retrospective analyses on the basis of the corrective approach to bias reduction produce identical bias-corrected maximum likelihood estimators of the odds ratio parameter, but this does not hold when using the preventive approach unless the case and control sample sizes are identical. We present some results on simulation and on the analysis of two real data sets.     

Variable selection in finite mixture of semi-parametric regression models

Abstract

In this paper we are concerned with variable selection in finite mixture of semiparametric regression models. This task consists of model selection for non parametric component and variable selection for parametric part. Thus, we encountered separate model selections for every non parametric component of each sub model. To overcome this computational burden, we introduced a class of variable selection procedures for finite mixture of semiparametric regression models using penalized approach for variable selection. It is shown that the new method is consistent for variable selection. Simulations show that the performance of proposed method is good, and it consequently improves pervious works in this area and also requires much less computing power than existing methods.     

A generalized semiparametric regression and its efficient estimation

We investigate a generalized semiparametric regression. Such a model can avoid the risk of wrongly choosing the base measure function. We propose a profile likelihood to efficiently estimate both parameter and nonparametric function. The main difference from the classical profile likelihood is that the profile likelihood proposed is a functional of the base measure function, instead of a function of a real variable. By making the most of the structure information of the semiparametric exponential family, we get an explicit expression of the estimator of the least favorable curve. It ensures that the new profile likelihood is computationally simple. Due to the use of the least favorable curve, the semiparametric efficiency is achieved successfully and the estimation bias is reduced significantly. Simulation studies can illustrate that our proposal is much better than the existing methodologies for most cases under study, and is robust to the different model conditions.     

A flexible semiparametric regression model for bimodal,asymmetric and censored data

In this paper, we propose a new semiparametric heteroscedastic regression model allowing for positive and negative skewness and bimodal shapes using the B-spline basis for nonlinear effects. The proposed distribution is based on the generalized additive models for location, scale and shape framework in order to model any or all parameters of the distribution using parametric linear and/or nonparametric smooth functions of explanatory variables. We motivate the new model by means of Monte Carlo simulations, thus ignoring the skewness and bimodality of the random errors in semiparametric regression models, which may introduce biases on the parameter estimates and/or on the estimation of the associated variability measures. An iterative estimation process and some diagnostic methods are investigated. Applications to two real data sets are presented and the method is compared to the usual regression methods.     

A Sample Selection Model with Skew‐normal Distribution

Non‐random sampling is a source of bias in empirical research. It is common for the outcomes of interest (e.g. wage distribution) to be skewed in the source population. Sometimes, the outcomes are further subjected to sample selection, which is a type of missing data, resulting in partial observability. Thus, methods based on complete cases for skew data are inadequate for the analysis of such data and a general sample selection model is required. Heckman proposed a full maximum likelihood estimation method under the normality assumption for sample selection problems, and parametric and non‐parametric extensions have been proposed. We generalize Heckman selection model to allow for underlying skew‐normal distributions. Finite‐sample performance of the maximum likelihood estimator of the model is studied via simulation. Applications illustrate the strength of the model in capturing spurious skewness in bounded scores, and in modelling data where logarithm transformation could not mitigate the effect of inherent skewness in the outcome variable.     

面板数据的自适应Lasso分位回归方法研究

如何在对参数进行估计的同时自动选择重要解释变量,一直是面板数据分位回归模型中讨论的热点问题之一。通过构造一种含多重随机效应的贝叶斯分层分位回归模型,在假定固定效应系数先验服从一种新的条件Laplace分布的基础上,给出了模型参数估计的Gibbs抽样算法。考虑到不同重要程度的解释变量权重系数压缩程度应该不同,所构造的先验信息具有自适应性的特点,能够准确地对模型中重要解释变量进行自动选取,且设计的切片Gibbs抽样算法能够快速有效地解决模型中各个参数的后验均值估计问题。模拟结果显示,新方法在参数估计精确度和变量选择准确度上均优于现有文献的常用方法。通过对中国各地区多个宏观经济指标的面板数据进行建模分析,演示了新方法估计参数与挑选变量的能力。     

Variable selection for semiparametric proportional hazards model under progressive Type-II censoring

Variable selection is an effective methodology for dealing with models with numerous covariates. We consider the methods of variable selection for semiparametric Cox proportional hazards model under the progressive Type-II censoring scheme. The Cox proportional hazards model is used to model the influence coefficients of the environmental covariates. By applying Breslow’s “least information” idea, we obtain a profile likelihood function to estimate the coefficients. Lasso-type penalized profile likelihood estimation as well as stepwise variable selection method are explored as means to find the important covariates. Numerical simulations are conducted and Veteran’s Administration Lung Cancer data are exploited to evaluate the performance of the proposed method.