Asymptotically optimal rank tests for the two-sample problem with randomly censored data

Using the methods of asymptotic decision theory asymptotically optimal rank tests are constructed in the two-sample testing problem for translation families and positive scale families under the assumption of equal censoring in both samples. The resulting tests have a simple form extending the known tests for un-censored data in a natural way. Relations to a recent proposal by Albers and Akritas are discussed.     

Affine Invariant Multivariate Sign and Rank Tests and Corresponding Estimates: a Review

The paper reviews recent contributions to the statistical inference methods, tests and estimates, based on the generalized median of Oja. Multivariate analogues of sign and rank concepts, affine invariant one-sample and two-sample sign tests and rank tests, affine equivariant median and Hodges–Lehmann-type estimates are reviewed and discussed. Some comparisons are made to other generalizations. The theory is illustrated by two examples.     

Testing nonparametric statistical functionals with applications to rank tests

The present paper discusses how nonparametric tests can be deduced from statistical functionals. Efficient and asymptotically most powerful maximin tests are derived. Their power function is calculated under implicit alternatives given by the functional for one – and two – sample testing problems. It is shown that the asymptotic power function does not depend on the special implicit direction of the alternatives but only on quantities of the functional. The present approach offers a nonparametric principle how to construct common rank tests as the Wilcoxon test, the log rank test, and the median test from special two-sample functionals. In addition it is shown that studentized permutation tests yield asymptotically valid tests for certain extended null hypotheses given by functionals which are strictly larger than the common i.i.d. null hypothesis. As example tests concerning the von Mises functional and the Wilcoxon two-sample test are treated.     

p-Value for two-Sample Linear Rank Tests Using Permutation Simulations and the Normal Approximation Method

Test statistics from the class of two-sample linear rank tests are commonly used to compare a treatment group with a control group. Two independent random samples of sizes m and n are drawn from two populations. As a result, N = m + n observations in total are obtained. The aim is to test the null hypothesis of identical distributions. The alternative hypothesis is that the populations are of the same form but with a different measure of central tendency. This article examines mid p-values from the null permutation distributions of tests based on the class of two-sample linear rank statistics. The results obtained indicate that normal approximation-based computations are very close to the permutation simulations, and they provide p-values that are close to the exact mid p-values for all practical purposes.     

A new look at rank tests in ordered-2×k contingency tables

We consider testing for association in contingency tables with 2 rows and k columns, where the columns represent ordered categories. If the rows are treatments and the columns are outcomes, this may be treated as a two-sample problem with all the outcomes tied at one of only k values. Then rank tests may be applied even without knowing the values. Some special considerations apply, however, and the most usual rank tests may not be the best ones. We use a graphical technique to compare the properties of various rank tests.     

Robust nonparametric tests for the two-sample location problem

We construct and investigate robust nonparametric tests for the two-sample location problem. A test based on a suitable scaling of the median of the set of differences between the two samples, which is the Hodges-Lehmann shift estimator corresponding to the Wilcoxon two-sample rank test, leads to higher robustness against outliers than the Wilcoxon test itself, while preserving its efficiency under a broad range of distributions. The good performance of the constructed test is investigated under different distributions and outlier configurations and compared to alternatives like the two-sample t-, the Wilcoxon and the median test, as well as to tests based on the difference of the sample medians or the one-sample Hodges-Lehmann estimators.     

Linear rank tests for censored survival data

We describe a class of rank test procedures for the two-sample problem with right censored survival data. The class of tests is directly generalized from the linear rank tests by assigning each observation a rank according to its corresponding Wilcoxon scores. It allows a flexible choice of score functions, in particular, those powerful against scale differences between the two survival distributions. Monte Carlo simulations have shown that some members of this class have great power in detecting crossing-curve alternatives (alternatives where underlying survival curves cross over). The class also contains tests essentially equivalent to the Gehan-Wilcoxon and the logrank tests.     

The extended two-sample problem: nonparametric case

The classical two-sample problem is extended here to the case where the distribution functions of the observable random variables are specified functions of unknown distribution functions and the null hypotheses to be tested or the parameters to be estimated relate to these unknown distributions. Various properties of the proposed rank tests and derived estimates are studied.     

Young chains and rank orders

Savage (1956) obtained an easily applied necessary condition for the admissibility of two-sample rank tests under alternatives having a monotone likelihood ratio. This condition is: rank order Z is more likely than rank order Z' if the Z-path is above the Z'-path in Young's lattice. This condition is easily applied and allows not only the proof of the inadmissibility of the Wilcoxon test under Lehmann alternatives but it can also be used to construct explicitly uniformly better tests. For Lehmann alternatives, we obtain another necessary criterion on rank orders which makes use of dominance.     

Smoothed alternatives of the two-sample median and Wilcoxon's rank sum tests

We discuss smoothed rank statistics for testing the location shift parameter of the two-sample problem. They are based on discrete test statistics – the median and Wilcoxon's rank sum tests. For the one-sample problem, Maesono et al. [Smoothed nonparametric tests and their properties. arXiv preprint. 2016; ArXiv:1610.02145] reported that some nonparametric discrete tests have a problem with their p-values because of their discreteness. The p-values of Wilcoxon's test are frequently smaller than those of the median test in the tail area. This leads to an arbitrary choice of the median and Wilcoxon's rank sum tests. To overcome this problem, we propose smoothed versions of those tests. The smoothed tests inherit the good properties of the original tests and are asymptotically equivalent to them. We study the significance probabilities and local asymptotic powers of the proposed tests.     

The chernoff efficiency of the wilcoxon rank test

Exact limiting Chernoff efficiencies of the Wilcoxon rank test are derived using Hoadley's results. Efficiency curves are derived for the two-sample Wilcoxon rank test relative to the two-sample t test for normal shift alternatives when the null hypothesis is that of common normality. The comparisons with Bahadur efficiency and small sample Hodges-Lehmann efficiency-are also made.     

Two sample nonparametric tests based on subsamples

The paper introduces a general class of nonparametric tests for the two-sample location problem based on subsamples. Includ- ed in this class is the Mann-Whitney (or the Wilcoxon rank sum) test. General formulas for the Pitman efficacy for different methods of subsampling are derived. A small sample power simu- lation compares the performance of members of this class     

A class of distribution-free tests for the two-sample slippage problem

A class of distribution-free tests for the two-sample slippage problem, when the random variables take only nonnegative values, is proposed. These tests are consistent and unbiased against the general slippage alternative. Recurrence relations for generating small sample significance points are given. The tests have been compared with the Savage test, the Wilcoxon test and the appropriate locally most powerful rank test by considering Pitman asymptotic relative efficiencies for several alternative hypotheses. Some of these tests exhibit considerable robustness in terms of efficiency for the various alternative hypotheses which are considered.     

A note on the nonparametric test based on theL 1-version of the Cramér-von Mises statistic

We consider the test based on theL ₁-version of the Cramér-von Mises statistic for the nonparametric two-sample problem. Some quantiles of the exact distribution under H₀ of the test statistic are computed for small sample sizes. We compare the test in terms of power against general alternatives to other two-sample tests, namely the Wilcoxon rank sum test, the Smirnov test and the Cramér-von Mises test in the case of unbalanced small sample sizes. The computation of the power is rather complicated when the sample sizes are unequal. Using Monte Carlo power estimates it turns out that the Smirnov test is more sensitive to non stochastically ordered alternatives than the new test. And under location-contamination alternatives the power estimates of the new test and of the competing tests are equal.     

Robustness without rank order statistics

An alternative to conventional rank tests based on a Euclidean distance analysis space is described. Comparisons based on exact probability values among classical two-sample t-tests and the Wilcoxon–Mann–Whitney test illustrate the advantages of the Euclidean distance analysis space alternative.     

Rank Tests for Clustered Survival Data

In a clinical trial, we may randomize subjects (called clusters) to different treatments (called groups), and make observations from multiple sites (called units) of each subject. In this case, the observations within each subject could be dependent, whereas those from different subjects are independent. If the outcome of interest is the time to an event, we may use the standard rank tests proposed for independent survival data, such as the logrank and Wilcoxon tests, to test the equality of marginal survival distributions, but their standard error should be modified to accommodate the possible intracluster correlation. In this paper we propose a method of calculating the standard error of the rank tests for two-sample clustered survival data. The method is naturally extended to that for K-sample tests under dependence.     

Conditional Studentized Survival Tests for Randomly Censored Models

It is shown that in the case of heterogenous censoring distributions Studentized survival tests can be carried out as conditional permutation tests given the order statistics and their censoring status. The result is based on a conditional central limit theorem for permutation statistics. It holds for linear test statistics as well as for sup-statistics. The procedure works under one of the following general circumstances for the two-sample problem: the unbalanced sample size case, highly censored data, certain non-convergent weight functions or under alternatives. For instance, the two-sample log rank test can be carried out asymptotically as a conditional test if the relative amount of uncensored observations vanishes asymptotically as long as the number of uncensored observations becomes infinite. Similar results hold whenever the sample sizes and are unbalanced in the sense that and hold.     

Nonparametric repeated significance tests for one-way anova with adoptation to multiple comparisons

Based on two-sample rank order statistics, a repeated significance testing procedure for a multi-sample location problem is considered. The asymptotic distribution theory of the proposed tests is given under the null hypothesis as well as under local alternatives. A Bahadur efficiency result of the repeated significance test relative to the terminal test based solely on the target sample size is presented. In the adaptation of the proposed tests to multiple comparisons, an asymptotically equivalent test statistic in terms of the rank estimators of the location parameters is derived from which the Scheffé method of multiple comparisons can be obtained in a convinient way.     

Modified Baumgartner statistics for the two-sample and multisample problems: a numerical comparison

Various non-parametric rank tests based on the Baumgartner statistic have been proposed for testing the location, scale and location–scale parameters. The modified Baumgartner statistics are not suitable for the scale shifts for a two-sample problem. Two modified Baumgartner statistics are proposed by changing the weight function. The suggested statistics are extended to the multisample problem. Some exact critical values of the suggested test statistics are evaluated. Simulations are used to investigate the power of the modified Baumgartner statistics.     

Bayes two-decision procedures for two-sample problems and rank-order data

A two-sample problem for rank-order data is formulated as a two-decision problem. Using the general Bayes solution, Bayes procedures are derived for several configurations of the set of states of nature including some for which the problem is distribution-free. It is shown that for certain prior distributions these procedures reduce to classical LMP rank tests. Some devices for selection of prior distributions are suggested. It is shown that the Bayes risk of these procedures tends to zero as sample sizes increase.