Volume estimation by monte carlo methods *

In estimating a multiple integral, it is known that Monte Carlo methods are more efficient than analytical techniques when the number of dimensions is beyond seven. In general, the sample-mean method is better than the hit-or-miss Monte Carlo method. However, when the volume of a domain in a high-dimensional space is of interest, the hit-or-miss method is usually preferred. It is because of the difficulty in generalizing the sample-mean method for the computation of the volume of a domain. This paper develops a technique to make such a generalization possible. The technique can be interpreted as a volume-preserving transformation procedure. A volume-preserving transformation is first performed to transform the concerned domain into a hypersphere. The volume of the domain is then evaluated by computing the volume of the hypersphere.     

Parameterization and inference for nonparametric regression problems

We consider local likelihood or local estimating equations, in which a multivariate function () is estimated but a derived function () of () is of interest. In many applications, when most naturally formulated the derived function is a non-linear function of (). In trying to understand whether the derived non-linear function is constant or linear, a problem arises with this approach: when the function is actually constant or linear, the expectation of the function estimate need not be constant or linear, at least to second order. In such circumstances, the simplest standard methods in nonparametric regression for testing whether a function is constant or linear cannot be applied. We develop a simple general solution which is applicable to nonparametric regression, varying-coefficient models, nonparametric generalized linear models, etc. We show that, in local linear kernel regression, inference about the derived function () is facilitated without a loss of power by reparameterization so that () is itself a component of (). Our approach is in contrast with the standard practice of choosing () for convenience and allowing ()> to be a non-linear function of (). The methods are applied to an important data set in nutritional epidemiology.     

Two tests for sequential detection of a change-point in a nonlinear model

In this paper, two tests, based on weighted CUSUM of the least squares residuals, are studied to detect in real time a change-point in a nonlinear model. A first test statistic is proposed by extension of a method already used in the literature but for the linear models. It is tested under the null hypothesis, at each sequential observation, that there is no change in the model against a change presence. The asymptotic distribution of the test statistic under the null hypothesis is given and its convergence in probability to infinity is proved when a change occurs. These results will allow to build an asymptotic critical region. Next, in order to decrease the type I error probability, a bootstrapped critical value is proposed and a modified test is studied in a similar way. A generalization of the Hájek–Rényi inequality is established.     

Investigating the sensitivity function's monotony of a health-related index

In this work it is investigated theoretically whether the support's length of a continuous variable, which represents a simple health-related index, affects the index's diagnostic ability of a binary health outcome. The aforementioned is attempted by studying the monotony of the index's sensitivity function, which is a measure of its diagnostic ability, in the cases that the index's distribution was either unknown or the uniform. The case of a composite health-related index which is formed by the sum of m component variables is also presented when the distribution of its component variables was either unknown or the uniform. It is proved that a health-related index's sensitivity is a non-decreasing function as to the finite length of its components' support, under certain condition. In addition, similar propositions are presented in the case that a health-related index is distributed normally according to its distribution parameters.     

A multiple warm standby δ-shock system with a repairman having multiple vacations

In this article, a warm standby n-unit system is studied. The system is operational as long as there is one unit normal. The unit online, which has a lifetime distribution governed by a phase-type distribution, is also attacked by a shock from some external causes. Assume that shocks arrive according to a Poisson process. Whenever an interarrival time of shock is less than a threshold, the unit online fails. The lifetimes of the units in warm standby is exponentially distributed. A repairman who can take multiple vacations repairs the failed units based on the “first-in-first-out” rule. The repair times and the vacation times of repairman are governed by different phase-type distributions. For this system, the Markov process governing the system is constructed. The system is studied in a transient and stationary regime; the availability, the reliability, the rates of occurrence of the different types of failures, and the working probability of the repairman are calculated. A numerical application is performed to illustrate the calculations.     

Eliciting expert judgements about a set of proportions

Eliciting expert knowledge about several uncertain quantities is a complex task when those quantities exhibit associations. A well-known example of such a problem is eliciting knowledge about a set of uncertain proportions which must sum to 1. The usual approach is to assume that the expert's knowledge can be adequately represented by a Dirichlet distribution, since this is by far the simplest multivariate distribution that is appropriate for such a set of proportions. It is also the most convenient, particularly when the expert's prior knowledge is to be combined with a multinomial sample since then the Dirichlet is the conjugate prior family. Several methods have been described in the literature for eliciting beliefs in the form of a Dirichlet distribution, which typically involve eliciting from the expert enough judgements to identify uniquely the Dirichlet hyperparameters. We describe here a new method which employs the device of over-fitting, i.e. eliciting more than the minimal number of judgements, in order to (a) produce a more carefully considered Dirichlet distribution and (b) ensure that the Dirichlet distribution is indeed a reasonable fit to the expert's knowledge. The method has been implemented in a software extension of the Sheffield elicitation framework (SHELF) to facilitate the multivariate elicitation process.     

Optimum reliability acceptance sampling plans under progressive type-I interval censoring with random removal using a cost model

A reliability acceptance sampling plan (RASP) is a variable sampling plan, which is used for lot sentencing based on the lifetime of the product under consideration. If a good lot is rejected then there is a loss of sales, whereas if a bad lot is accepted then the post sale cost increases and the brand image of the product is affected. Since cost is an important decision-making factor, adopting an economically optimal RASP is indispensable. This work considers the determination of an asymptotically optimum RASP under progressive type-I interval censoring scheme with random removal (PICR-I). We formulate a decision model for lot sentencing and a cost function is proposed that quantifies the losses. The cost function includes the cost of conducting the life test and warranty cost when the lot is accepted, and the cost of batch disposition when it is rejected. The asymptotically optimal RASP is obtained by minimizing the Bayes risk in a set of decision rules based on the maximum likelihood estimator of the mean lifetime of the items in the lot. For numerical illustration, we consider that lifetimes follow exponential or Weibull distributions.     

A Tree-Structured Markovian Model of the Shipment Consolidation Process

This article studies the dispatch of consolidated shipments. Orders, following a batch Markovian arrival process, are received in discrete quantities by a depot at discrete time epochs. Instead of immediate dispatch, all outstanding orders are consolidated and shipped together at a later time. The decision of when to send out the consolidated shipment is made based on a “dispatch policy,” which is a function of the system state and/or the costs associated with that state. First, a tree structured Markov chain is constructed to record specific information about the consolidation process; the effectiveness of any dispatch policy can then be assessed by a set of long-run performance measures. Next, the effect on shipment consolidation of varying the order-arrival process is demonstrated through numerical examples and proved mathematically under some conditions. Finally, a heuristic algorithm is developed to determine a favorable parameter of a special set of dispatch policies, and the algorithm is proved to yield the overall optimal policy under certain conditions.     

Optimal Sequential Design in a Controlled Non-parametric Regression

Abstract. In a non‐parametric regression, the heteroscedasticity (dependence of the variance of the regression error on the predictor) can be a serious complication in estimation or visualization of an underlying regression function. If a controlled sampling is permitted, then the statistician can choose the design of predictors which attenuates the effect of heteroscedasticity. It is proposed to use a design which minimizes the mean integrated squared error of the regression function estimation. Then the corresponding optimal design density is proportional to the standard deviation of the regression error (the so‐called scale function). Because in general the statistician does not know an underlying scale function, the natural question is as follows: is it possible to suggest a sequential design which performs as well as an oracle that knows the underlying scale function? The answer is ‘yes’, and a corresponding sequential procedure is developed. It is proved, for the first time in the literature, that a data‐driven sequential design, together with an adaptive regression estimator, can mimic the oracle and be sharp minimax. Further, it is shown that the suggested method is feasible for small samples.     

Bayesian approaches to the detection of outliers in poisson samples

This paper is concerned with the detection of upper outliers in a Poisson sample.The approach is Bayesian throughout. It is supposed that a small number of observations are contaminated, that is they are generated from a Poisson sample with mean inflated by a factor §.Bayes factors for the cases when (i) § is known, (ii) it is given a proper conjugate prior or (iii) it is completely unknown are discussed. It is suggested, in contrast to classical approaches, that transforming the data to normality does not simplify the problem.     

Limits of quantitation for laboratory assays

Summary.  A common problem with laboratory assays is that a measurement of a substance in a test sample becomes relatively imprecise as the concentration decreases. A standard solution is to establish lower limits for reliable measurement. A quantitation limit is a level above which a measurement has sufficient precision to be reliably reported. The paper proposes a new approach to defining the limit of quantitation for the case where a linear calibration curve is used to estimate actual concentrations from measured values. The approach is based on the relative precision of the estimated concentration, using the delta method to approximate the precision. A graphical display is proposed for the assessment of estimated concentrations, as well as the overall reliability of the calibration curve. Our research is motivated by a clinical inhalation experiment. Comparisons are made between the approach proposed and two standard methods, using both real and simulated data.     

A New Method for Testing Interaction in Unreplicated Two-Way Analysis of Variance

For a two-way ANOVA table, with a single observation per cell, the standard approach is to assume that interaction between the two factors is negligible, and to base inferences about the main factors on the model without interaction. But there is no totally satisfactory method for testing if interaction can be ignored. The classical approach is to specify a functional form for the interaction terms, involving a small number of parameters, and then use an appropriate test. But, such tests have low power if the functional form is inappropriate. This has led researchers to propose tests which do not assume a specific form for the interactions. In this article, we present a new approach for testing interaction which also does not assume a specific form for the interaction. This approach is fairly simple and flexible, and its usefulness is illustrated with several examples. We also present a general result which shows that there is no test of interaction with good power properties against all types of interaction.     

A new two-sample test for choosing between log-rank and Wilcoxon tests with right-censored data

When differences of survival functions are located in early time, a Wilcoxon test is the best test, but when differences of survival functions are located in late time, using a log-rank test is better. Therefore, a researcher needs a stable test in these situations. In this paper, a new two-sample test is proposed and considered. This test is distribution-free. This test is useful for choosing between log-rank and Wilcoxon tests. Its power is roughly the maximal power of the log-rank test and Wilcoxon test.     

Adjusting the bias of adaptive sampling estimators of spatial dispersion indexes by the δ-method

It is common practice to investigate the spatial dispersion in a community of discrete individuals (like animals or plants). Usually, the study area is partitioned into spatial units of equal size and then the relationship between the first two moments of the variable representing the number of individuals in each plot is investigated. When the points are spread over a very wide area so that the population density is low but many points are concentrated inside a few units, then a suitable sample method for estimating the first two moments is adaptive sampling. However, since the more common dispersion indexes are non linear function of the first two moments, the resulting estimators are biased for finite samples. Accordingly, a procedure to adjust bias is required for small samples. In this paper a δ-method evaluation of the bias is proposed and the asymptotic distribution of the bias-corrected estimators is provided. Finally, a simulation study is performed in order to investigate the performance of the proposed procedure.     

A statistical test for the hypothesis of Gaussian random function

A Gaussian random function is a functional version of the normal distribution. This paper proposes a statistical hypothesis test to test whether or not a random function is a Gaussian random function. A parameter that is equal to 0 under Gaussian random function is considered, and its unbiased estimator is given. The asymptotic distribution of the estimator is studied, which is used for constructing a test statistic and discussing its asymptotic power. The performance of the proposed test is investigated through several numerical simulations. An illustrative example is also presented.     

The Poisson-exponential model for recurrent event data: an application to bowel motility data

This paper presents a new parametric model for recurrent events, in which the time of each recurrence is associated to one or multiple latent causes and no information is provided about the responsible cause for the event. This model is characterized by a rate function and it is based on the Poisson-exponential distribution, namely the distribution of the maximum among a random number (truncated Poisson distributed) of exponential times. The time of each recurrence is then given by the maximum lifetime value among all latent causes. Inference is based on a maximum likelihood approach. A simulation study is performed in order to observe the frequentist properties of the estimation procedure for small and moderate sample sizes. We also investigated likelihood-based tests procedures. A real example from a gastroenterology study concerning small bowel motility during fasting state is used to illustrate the methodology. Finally, we apply the proposed model to a real data set and compare it with the classical Homogeneous Poisson model, which is a particular case.     

ELICITING A DIRECTED ACYCLIC GRAPH FOR A MULTIVARIATE TIME SERIES OF VEHICLE COUNTS IN A TRAFFIC NETWORK

The problem of modelling multivariate time series of vehicle counts in traffic networks is considered. It is proposed to use a model called the linear multiregression dynamic model (LMDM). The LMDM is a multivariate Bayesian dynamic model which uses any conditional independence and causal structure across the time series to break down the complex multivariate model into simpler univariate dynamic linear models. The conditional independence and causal structure in the time series can be represented by a directed acyclic graph (DAG). The DAG not only gives a useful pictorial representation of the multivariate structure, but it is also used to build the LMDM. Therefore, eliciting a DAG which gives a realistic representation of the series is a crucial part of the modelling process. A DAG is elicited for the multivariate time series of hourly vehicle counts at the junction of three major roads in the UK. A flow diagram is introduced to give a pictorial representation of the possible vehicle routes through the network. It is shown how this flow diagram, together with a map of the network, can suggest a DAG for the time series suitable for use with an LMDM.     

A Multiplicative Alo-group Based Hierarchical Decision Model and Application

Pairwise comparison matrix (PCM) is a popular technique used in multi-criteria decision making. The abelian linearly ordered group (alo-group) is a powerful tool for the discussion of PCMs. In this article, a criterion for acceptable consistency of PCM is introduced, which is independent of the scale and can be intuitively interpreted. The relation of the introduced criterion with the weak consistency is investigated. Then, a multiplicative alo-group based hierarchical decision model is proposed. The following approaches are included: (1) the introduced criterion for acceptable consistency is used to check whether or not a PCM is acceptable; (2) the row’s geometric mean method is used for deriving the local priorities of a multiplicative PCM; (3) a Hierarchy Composition Rule derived from the weighted mean is used for computing the criterion/subcriterion’s weights with regard to the total goal; and (4) the weighted geometric mean is used as the aggregation rule, where the alternative’s local priorities are min-normalized. The proposed model has the property of preserving rank. Moreover, it has counterparts in the additive case. Finally, the model is applied to a layout planning problem of an aircraft maintenance base with a computer-based software.     

Monitoring and change-point estimation for spline-modeled non-linear profiles in phase II

In some applications of statistical quality control, quality of a process or a product is best characterized by a functional relationship between a response variable and one or more explanatory variables. This relationship is referred to as a profile. In certain cases, the quality of a process or a product is better described by a non-linear profile which does not follow a specific parametric model. In these circumstances, nonparametric approaches with greater flexibility in modeling the complicated profiles are adopted. In this research, the spline smoothing method is used to model a complicated non-linear profile and the Hotelling T² control chart based on the spline coefficients is used to monitor the process. After receiving an out-of-control signal, a maximum likelihood estimator is employed for change point estimation. The simulation studies, which include both global and local shifts, provide appropriate evaluation of the performance of the proposed estimation and monitoring procedure. The results indicate that the proposed method detects large global shifts while it is very sensitive in detecting local shifts.     

Maximum Test versus Adaptive Tests for the Two-Sample Location Problem

For the non-parametric two-sample location problem, adaptive tests based on a selector statistic are compared with a maximum and a sum test, respectively. When the class of all continuous distributions is not restricted, the sum test is not a robust test, i.e. it does not have a relatively high power across the different possible distributions. However, according to our simulation results, the adaptive tests as well as the maximum test are robust. For a small sample size, the maximum test is preferable, whereas for a large sample size the comparison between the adaptive tests and the maximum test does not show a clear winner. Consequently, one may argue in favour of the maximum test since it is a useful test for all sample sizes. Furthermore, it does not need a selector and the specification of which test is to be performed for which values of the selector. When the family of possible distributions is restricted, the maximin efficiency robust test may be a further robust alternative. However, for the family of t distributions this test is not as powerful as the corresponding maximum test.