Estimation of percentile residual life function with left-truncated and right-censored data

This article focuses on the estimation of percentile residual life function with left-truncated and right-censored data. Asymptotic normality and a pointwise confidence interval that does not require estimating the unknown underlying distribution function of the proposed empirical estimator are obtained. Some simulation studies and a real data example are used to illustrate our results.     

The percentile residual life up to time t0: Ordering and aging properties

Motivated by practical issues, a new stochastic order for random variables is introduced by comparing all their percentile residual life functions until a certain instant. Some interpretations of these stochastic orders are given, and various properties of them are derived. The relationships to other stochastic orders are studied and also an application in reliability theory is described. Finally, we present some characterization results of the decreasing percentile residual life up to time t₀ aging notion.     

Comparison of two life distributions on the basis of their percentile residual life functions

Let F and G be life distributions with respective failure rate functions r_F and r_G and respective 100α-percentile (0 < α < 1) residual life functions q_{α, F}, and q_{α, G}. Distribution-free two-sample tests are proposed for testing H₀: F = G against H_1,α,: q_{α, F} ≥ q_{α, G} and H_{2 α}: q_{β, F} ≥ q_β,G for all β ≥ α. This class of tests includes as a special case the test of Kochar (1981) for the alternative H*₂: r_F ≤ r_G. A theorem of Govindarajulu (1976) is extended in order to obtain asymptotic normality of the test statistics. The condition q_{α, F} ≥ q_{α, G} is implied by r_F ≤ r_G and is unrelated to the stochastic ordering F≤ G; if F and G are Weibull distributions with respective shape parameters c₁ and c₂ such that 1 ≤ C₁ < C₂, then q_α,F ≥ q_{α, G} for all α larger than a function of the parameters.     

Conditional mean residual life functions

In this paper a conditional mean residual life in the context of reliability theory is introduced. The properties of the conditional mean residual life are studied. Various characterizations by the conditional mean residual life are proposed.     

Jackknife empirical likelihood test for mean residual life functions

Mean residual life (MRL) function is an important function in survival analysis which describes the expected remaining life given survival to a certain age. In this article, we propose a non parametric method based on jackknife empirical likelihood through a U-statistic to test the equality of two mean residual functions. The asymptotic distribution of the test statistic has been derived. Simulations are conducted to illustrate the performance of the proposed test under different distributional assumptions and compare with some existing method. The proposed method is then applied to two real datasets.     

Aspects of the mean residual life order for weighted distributions

In this paper, we first provide conditions for preservation of the mean residual life (mrl) order under weighting. Then we apply the obtained results to establish our results about preservation of the decreasing mrl class by weighted distributions. In addition, we present some results for comparing the original random variable to its weighted version in terms of the mrl order. Also, some examples are given to illustrate the results.     

Asymptotic equivalence between two empirical mean residual life processes

There are two mean residual life estimates for right censored data. One is based on the Kaplan-Meier estimate, the other, based on the Susarla-Van Ryzin estimate for survival function. In this paper, we define the empirical mean residual life process for right censored data and show that the two empirical mean residual life processes based on the Kaplan-Meier and Susarla-Van Ryzin estimates are asymptotically equivalent uniformly on an interval under some conditions. Also we discuss the case which the asymptotic equivalence might fail.     

Bounds of moment generating functions of some life distributions

In this article we show that if a life has new better than used in expectation (NBUE) ageing property and if the mean life is finite then the moment generating function exists and is finite. In fact, the moment generating function is shown to be bounded above by that of the exponential distribution with the same mean. Analogous results are also proven for two much bigger families of life distribution, namely, the new better than renewal used in expectation (NBRUE) and the renewal new is better than used in expectation (RNBUE) and the renewal new better than renewal used in expectation (RNBRUE), provided that the life has finite two moments. Further, stronger results are also obtained for the smaller new better than used version of the above classes.     

Covariate effect on the life expectancy and percentile residual life functions under the proportional hazards and the accelerated life models

The present paper is concerned with statistical models for the dependence of survival time or time to occurrence of an event, such as time to tumor, on a vector X of covariates or prognostic variables such as age, sex, blood pressure, length of exposure to a toxic material, etc., measured on a group of individuals in biomedical investigations. It is assumed that the covariates influence the distribution of time to tumor only through a linear predictor μ =β^′X.

The object of our paper is to investigate the effect due to the covariates on the Life Expectancy and the Percentile Residual Life (PRL) function of a family of organisms under the proportional hazards and the accelerated life models. The key result is that the families of survival distributions under these models have the 'setting the clock back to zero' property if the family of baseline survival distributions does. This property is a generalization of the lack of memory property of the exponential distribution. Simple examples of the members of this family are the linear hazard exponential, Pareto and Gompertz life distributions.

As a simple application of the main results obtained in the present paper, we have considered a stochastic survival model recently proposed by Chiang and Conforti (1989) for the time-to-tumor distribution in the context of a large-scale serial sacrifice experiment by the National Center of Toxicological Research (NCTR). This involves some mice that were fed 2-AAF from infancy and those that developed bladder and/or liver neoplasms, see Farmer et al (1980). It is shown that their stochastic model for tumor incidence intensity at time t leads to a family of survival models that has the setting the clock back to zero property. The survival functions and the effect of the vector X of covariates on the PRL and the tumor-free life expectancies are evaluated for the proportional hazards and accelerated life models.     

Empirical likelihood based detection procedure for change point in mean residual life functions under random censorship

The mean residual life (MRL) function is one of the basic parameters of interest in survival analysis that describes the expected remaining time of an individual after a certain age. The study of changes in the MRL function is practical and interesting because it may help us to identify some factors such as age and gender that may influence the remaining lifetimes of patients after receiving a certain surgery. In this paper, we propose a detection procedure based on the empirical likelihood for the changes in MRL functions with right censored data. Two real examples are also given: Veterans' administration lung cancer study and Stanford heart transplant to illustrate the detecting procedure. Copyright © 2016 John Wiley & Sons, Ltd.     

Classical estimation of hazard rate and mean residual life functions of Pareto distribution

Abstract

In this paper we find the maximum likelihood estimates (MLEs) of hazard rate and mean residual life functions (MRLF) of Pareto distribution, their asymptotic non degenerate distribution, exact distribution and moments. We also discuss the uniformly minimum variance unbiased estimate (UMVUE) of hazard rate function and MRLF. Finally, two numerical examples with simulated data and real data set, are presented to illustrate the proposed estimates.     

Some characterizations of multivariate distributions using products of the hazard gradient and mean residual life components

We give a general procedure to characterize multivariate distributions by using products of the hazard gradient and mean residual life components. This procedure is applied to characterize multivariate distributions as Gumbel exponential, Lomax, Burr, Pareto and generalized Pareto multivariate distributions. Our results extend the results of several authors and can be used to study how to extend univariate models to the multivariate set-up.     

Monotony relations between distribution functions and their application to experimental design

In a linear regression model an estimator of the unknown coefficients is considered which, in special cases, includes the least squares estimator. In the ease of stable symmetric error distribution and by means of a certain monotony relation between distribution functions optimality of this estimator is proved and the designing problem is investigated. A robustness property of optimal designs against the designing criterion and some conclusions are given concerning the least squares estimator in the case of G- and C-optimality.     

Some results on residual life and inactivity time at random time

In this article, we enhance the study of residual life at random time (RLRT) and inactivity time at random time (ITRT). To this aim, first we provide some stochastic orderings results among ITRT in two-sample problems when they failed at two different random times. Then, we develop some sufficient conditions which lead to the stochastic comparisons of RLRT and ITRT based on variance residual life order. The results are expected to be useful in reliability theory, forensic science, queue theory, and actuarial science.     

Nonparametric estimator for mean residual life and vitality function

In this paper, we study the estimation of the vitality function(v(x)=E(X|X>x) and mean residual life function(e(x)=E(X-x|X>x) from a sample ofX using the empirical estimator and kernel estimator. Under suitable conditions of regularity, the asymptotic normality of the kernel estimator is obtained. Partially supported by Consejeria de Cultura y Ed. (C.A.R.M.), under Grant PIB 95/90.