Space,time, and self: Rethinking aging in the contexts of immigration and transnationalism

Critical gerontology views aging as a social construction that reflects the intersections of micro-processes with the macro-level forces of individual aging experiences. In the contexts of immigration and transnationalism, however, the macro-structural conditions, dynamics and experiences of aging have become further diversified and complicated. The dearth of empirical and explanatory knowledge in this area has inhibited us from comprehending aging in a changing world. Drawing on data from a study of Chinese grandparents' experiences of transnational caregiving in Canada, this article examines the impacts of such experiences on three interconnected dimensions – spatial, temporal and cognitive – of aging. Although the practice of transnational caregiving allows skilled immigrant families to mobilize care resources outside Canada, it has not only ruptured the traditional trajectories of aging for their elderly parents, but also complicated the inequalities that they have to bear on individual, familial and transnational levels. I argue that the critical examination of aging in the context of transnational caregiving helps us take into consideration those dimensions (such as place, space, time, and knowledge) that are changed by immigration processes, and rethink aging from a broader perspective that links seniors' experiences with their relationship with their adult immigrant children's families and macro-structures outside national borders.     

Oxidative mutagenesis, mismatch repair, and aging

A PubMed search for the term "oxidative stress" yields over 29,000 articles published on the subject over the past 10 years; more than 2000 of these articles also include the term "aging" in their title or abstract. Many theories of aging predict causal roles for oxidative stress in the myriad of pathological changes that occur as a function of age, including an increasing propensity to develop cancer. A possible link between aging and cancer is the induction and accumulation of somatic mutations caused by oxidative stress. This Review focuses on small mutational events that are induced by oxidative stress and the role of mismatch repair (MMR) in preventing their formation. It also discusses a possible inhibitory effect of oxidative stress on MMR. We speculate that a synergistic interaction between oxidative damage to DNA and reduced MMR levels will, in part, account for an accumulation of small mutational events, and hence cancer, with aging.     

Aging in Which Place? Connecting Aging in Place with Individual Responsibility,Housing Markets,and the Welfare State

This article proposes an analytical framework for the understanding of aging in place, and asks: Which housing alternatives are compatible with aging in place? Who are responsible for providing housing in old age? A literature review demonstrates that there is no agreement on the “place” in aging in place, but that aging in place policies entail joint individual and public responsibility for housing. An empirical example demonstrates different policy expressions of aging in place at national and local government levels in Norway. The article questions whether a need to move to receive care is compatible with aging in place.     

Aging,Health, and Social Policy:

Seven major turning points in the evolution of U.S. aging policy are identified and reviewed: (1) the Social Security Act (2) the Great Society (3) the federalization of Old Age Assistance (4) the enactment of comprehensive social services (5) Social Security improvements (6) New Federalism, and (7) medical cost-containment policies under Medicare and Medicaid. In the 1980s, significant and growing problems of uninsurance and underinsurance for health care have re-emerged. Simultaneously, state Medicaid programs are characterized by their increasing variation and inequities, while there has been a decline in access for the poor. The future of aging policy will be decided in the context of four socio-demographic realities: (1) population aging (2) trends in mortality and morbidity (3) the relationship between income and health, and (4) aging as a woman's issue. The article concludes with a call for a recommitment to the public interest and to public solutions which affirm that health care is an inalienable right.     

Aging at the interface of stem cell renewal, apoptosis, senescence, and cancer

The aging-related research field has focused on the detection of genetic factors that affect the aging process, but more recently scientists have started to shift their attention to novel and more integrative ways of studying cellular and organismal function. Such approaches allow them to uncover and explore unexpected patterns and themes, resulting in a more comprehensive knowledge of the complex regulatory pathways and networks involved in aging and age-related diseases. Eventually, this knowledge will lead to a systems-level understanding of aging. The third "Functional Genomics of Aging" conference held in Palermo, Italy, in March/April 2006 highlighted some of the more exciting work in this area.     

Decentralization, aging policy, and the age of Clinton

This article examines the recent trends in decentralization and their implications for aging policy in the Clinton presidency. It first discusses a decade-long trend toward decentralizing policy and then examines some recent federal enactments that promote more discretion by state and local policymakers, suggesting that these may set the framework for aging policy during most of Clinton's first term. A basic premise of the discussion is, however, that the degree of flexibility varies with the policy area being analyzed-housing, transportation, health and social services--and whether these are "old" (pre-1980s) or "new" (post-1980s) policies. It concludes with the suggestion that a dual-centered, shared federal-state solution may provide the best approach to the premier issue in aging policy today-long-term care.     

Come one, come all

Aging is a complex process that involves the gradual functional decline of many different tissues and cells. Gene expression microarray analysis provides a comprehensive view of the gene expression signature associated with age and is particularly valuable for understanding the molecular mechanisms that contribute to the aging process. However, because of the stochastic nature of the aging process, animals of the same chronological age often manifest great physiological differences. Therefore, profiling the gene expression pattern of a large population of aging animals risks either exaggerating or masking the changes in gene expression that correspond to physiological aging. In a recent paper, Golden and Melov surveyed the gene expression profiles of individual aging Caenorhabditis elegans, hoping to circumvent the problem of variability among worms of the same chronological age. This initial analysis of age-dependent gene expression in individual aging worms is an important step toward deciphering the molecular basis of physiological aging.     

Mindfulness, vulnerability, and love: Spiritual lessons from frail elders, earnest young pilgrims, and middle aged rockers

Gerontologists have studied religion and spirituality for almost three decades. Much of this work focuses on determining how elders' religious and spiritual beliefs and practices affect various indicators of well-being. This paper critiques many of the assumptions underlying this research and suggests alternatives to individualistic formulations of well-being. Experiences in spiritual communities of various types may help aging persons to be mindfully present to others, to recognize that all are vulnerable to the afflictions of aging and the certainty of death, and to love and care for others while working to promote justice. In this paper, I describe how my marriage to a minister enabled me to develop relationships with frail elders and young adults seeking to live faithfully. These friends have influenced my work and have helped to shape my views on my own aging.     

Older Gay,Lesbian, and Bisexual Adults: Tools for Age-Competent and Gay Affirmative Practice

This article presents a demographic snapshot of older GLB adults, discusses the barriers to service provision, and melds aging competencies with that of affirmative practice with GLB individuals. Its goals are to delineate the specific knowledge, attitudes, and skills recommended for age-competent and gay affirmative practice with an aging GLB population.     

Building a Humane Society for Older People: Compassionate Policy Making for Integration,Participation, and Positive Ageing Within a Framework of Intergenerational Solidarity

This article explores the global challenge of population aging with a specific focus on the concepts of integration and participation of older people in society within the context of “realizing a society for all ages” as promoted by the United Nations. It is proposed that governments worldwide need to embrace new ways of thinking about population aging that include strategic initiatives for strengthening the social contract that fosters generational interdependence. The meaning of “positive aging” is explored at both the individual and social levels, with implications for quality-of-life issues involving intergenerational relationships. The point is made that while the promotion of positive aging is commendable on both philosophical and health grounds it can be problematic for those older people who for a range of legitimate reasons are unable to fulfill the notion of positive or active aging. The longevity revolution will require the emergence of a more humane society that undertakes to reconceptualize what older age means, together with exploring new ways of enhancing the citizenship status of older people through the development and promotion of innovative intergenerational relationships. A call is made for a wider engagement of the citizenry in the processes involved in the formulation and implementation of policy making.     

Comparative analysis of aging policy reforms in Argentina,Chile, Costa Rica,and Mexico

This investigation uses case studies and comparative analysis to review and analyze aging policy in Argentina, Chile, Costa Rica, and Mexico and uncovers similarities and relevant trends in the substance of historical and current aging policy across countries. Initial charity-based approaches to poverty and illness have been gradually replaced by a rights-based approach considering broader notions of well-being, and recent reforms emphasize the need for national, intersectoral, evidence-based policy. The results of this study have implications for understanding aging policy in Latin America from a welfare regime and policy makers’ perspective, identifying priorities for intervention and informing policy reforms in developing countries worldwide.     

Enhancing the mind? Memory medicine, dementia, and the aging brain

The study explores the relationship between the neurosciences, aging, anti-aging culture, memory medicine, and the hypercognitive society. The first part traces the discourses of mind from the Enlightenment to contemporary biosocial models where the aging brain has become a social laboratory for research, experimentation, and intervention. The second part explores the Cholinergic Hypothesis, the development of the cholinesterase inhibitors and their recent implementation in cases of Mild Cognitive Impairment (MCI). Critical questions are posed about how the mission to optimize aging has affected projects to enhance the mind.     

Ubiquitin,proteasomes, and the aging brain

Ubiquitinated proteinaceous inclusions are the hallmark of many neurodegenerative diseases. Inefficient proteolysis might lead to the accumulation and ultimate deposition of potentially toxic entities as inclusions within neurons or glial cells. This hypothesis is supported by genetic evidence both from patient populations and from engineered mutations in genes that encode ubiquitin/proteasome components in mice. The appearance of similar inclusions in the brains of elderly individuals of normal and subclinical conditions begs the question of whether there is a general age-related decline in the ability of the ubiquitin/proteasome pathway (UPP) to recognize and eliminate abnormal proteins, and whether such a decline would be reflected by changes in the abundance or activity of some or all components of the UPP. Here we describe alterations in the aging mammalian brain that correlate with a decline in the function of the UPP and review the evidence for age-related changes in specific UPP components. These alterations are discussed within the context of prevalent theories of aging.     

Support for aging policy: Self-interest, social justice, and political symbols

This article explores and evaluates theoretical assumptions implied by the familiar hypothesis that anti-elderly scapegoating rhetoric is producing attitude change with respect to citizen support for aging policy. An explanation—the self-interest model—that is consistent with both this hypothesis and existing attitude theory is presented. It is contrasted with a second hypothesis emphasizing the role played by symbolic political attitudes in the formation of citizen policy positions. Survey data from the state of Kansas indicate no support for either the self-interest explanation of aging policy attitudes or for the hypothesized impact of anti-elderly rhetoric.     

中国老龄产业发展的现状、前景与政策支持体系

总体上看,目前我国老龄产业中的养老服务业、老年教育业和老年住宅业都呈现快速兴起的势头,但产业带动经济和就业局面尚未形成,产业发展城乡间、东中西部间失衡,政策扶持和规范缺位,福利色彩仍然浓厚,产品与服务促销和销售手段相对落后,市场研究与产品开发不足。新形势下人口、经济、政策宏观背景及家庭结构、代际关系和养老观念的微观变革为我国老龄产业发展提供了广阔的前景。同时,现阶段我国老龄产业的发展迫切需要一个完善有效的政策支持体系。     

Introduction: The aging workforce: challenges for societies, employers, and older workers

The aging of the baby boom cohorts poses challenges for societies, employers, and the baby boomers themselves: Will societies be able to sustain an exponentially increasing number of retirees and older workers? Will employers be prepared to accommodate an aging workforce, especially in times of economic recession? Will aging baby boomers desire and be able to postpone retirement and remain in their career jobs or seek bridge employment or be forced to do so out of financial necessity?     

Mitochondrial bioenergetics, aging, and aging-related disease

In this Perspective, the author discusses some of the bioenergetic consequences of the various alterations in mitochondrial function that have been hypothesized to be associated with human aging and aging-related disease. Special focus is afforded to neurodegenerative disease.     

Aging as intracohort differentiation: Accentuation,the Matthew effect,and the life course

Recent contributions of sociologists and others have brought a new awareness and new theoretical understanding of the extent to which human aging and life-course patterns are shaped by social conditions and influenced by social change. Yet the potential of many social processes to account for individual aging patterns remains untapped, because research and theory have focused heavily upon comparisons between cohorts rather than the internal differentiation of cohorts. This paper shows that focusing upon intracohort differentiation over the life course leads to a mobilization of sociological findings whose age-related implications have not been exploited. Using the phenomenon of aged heterogeneity as an illustrative case, it is suggested that intracohort differentiation—operating through macro-level, organizational, and micro-level processes—can explain significant phenomena of aging previously neglected by theory, or else assumed to be psychological in origin. These processes specify Merton's Matthew effect. Implications for biological aging and for research are briefly discussed.     

New sex for old: lifestyle,consumerism, and the ethics of aging well

This article explores the convergence of consumer society and professional expertise in reinventing notions of maturity, aging, lifecourse, and senior citizenry. As positive ideals of aging buoyed by health agendas around independence, well being, and mobility replace negative stereotypes of decline and dependency, market and lifestyle industries create an idealized culture of “ageless” consumers and active populations. In relation to this culture, this article raises two issues. First, how are consumer ethics associated with choice, risk management, and self-care built into new identities around the aging body? Second, how have sexuality in general and new concepts of sexual “function” in particular emerged as pivotal concerns for rehabilitating the aging body and negotiating successful lifestyles? These questions are explored through an analysis of health, sexological, and marketing materials directed at both men and women.