The Construction of Optimal Imcomplete Block Designs When Observations Within a Block are Correlated

An algorithmic method is described for the construction of optimal incomplete block designs when a known correlation structure is assumed for observations from plots in the same block. The method is applicable to a wide class of designs and correlation structures. Some examples are given to illustrate the procedure.     

Neighbor-Balanced Bipartite Block Designs

This article deals with the neighbor-balanced block design setting when there are two disjoint sets of treatments, one set consisting of test treatments and the other of control treatments. The interest here is to estimate the contrasts pertaining to test treatments vs. control treatments (with respect to direct and neighbors) with as high precision as possible. Some series of neighbor-balanced block designs for comparing a set of test treatments to a set of control treatments have been developed. The designs obtained are totally balanced in the sense that all the contrasts among test treatments for direct and neighbor effects are estimated with same variance and all the contrasts pertaining to test vs. control for direct and neighbor effects are estimated with the same variance.     

On Universal Optimality of Circular Weakly Neighbor Balanced Designs Under an Interference Model

In this article, the optimal design problem in a fixed effects interference model with left-neighbor effects is studied. It is known (Druilhet, 1999 Druilhet , P. ( 1999 ). Optimality of circular neighbor balanced designs . J. Statist. Plann. Infer. 81 : 141 – 152 .[Crossref], [Web of Science ®] , [Google Scholar]) that circular neighbor balanced designs (CNBDs) are universally optimal in such a model. We prove the universal optimality of circular weakly neighbor balanced designs (CWNBDs), which require a smaller number of blocks than CNBDs. CWNBDs with the number of blocks smaller than the number of treatments belong to the class of partially neighbor balanced designs (PNBDs) defined by Wilkinson et al. (1983 Wilkinson , G. N. , Eckert , R. , Hancock , T. W. , Mayo , O. ( 1983 ). Nearest neighbour (NN) analysis of field experiments . J. Roy. Statist. Soc. Ser. B 45 : 151 – 210 . [Google Scholar]). We give a construction method for some CWNBDs, with examples.     

Circular balanced repeated measurements designs

The concept of a circular design is defined and when proper balance for various effects is assumed, its universal optimality is proved over the class of all designs with the same set of parameters, Such designs are shown to minimize the variance of the best linear unbiased estimators of contrasts of residual and direct effects over the class of equireplicated designs. All models assume first order residual effects and are of a circular nature. The proofs are presented in a unified manner for several models at a time. They are based on certain matrix domination which occurs when parameters are eliminated from a linear modelj this latter fact is proved for a general linear model.     

Universally Optimal Designs Balanced for Neighbor Effects

The performance of a treatment is affected by the treatments applied to its adjacent plots, especially in the experiments of agriculture, horticulture, forestry, serology and industry. Neighbor designs ensure that treatment comparisons are least affected by neighbor effects, therefore, this is a rich field of investigation. In this paper, criterion for construction of universally optimal neighbor balanced designs is discussed.     

The Construction of Optimal Balanced Incomplete Block Designs When Adjacent Observations are Correlated

An algorithm is described for the optimal rearrangement of the treatments within each block of a Balanced Incomplete Block Design when a specified “nearest neighbour” correlation structure exists among observations from plots in the same block. The procedure uses results obtained by Kiefer & Wynn (1981). Designs obtained using the algorithm are found to compare favourably with those produced by combinatorial methods given in Cheng (1983). The algorithm produces optimal designs for all BIBD parameter sets, including those not covered by the results of Kiefer & Wynn or Cheng.     

On the Optimality of Circular Block Designs Under a Mixed Interference Model

Filipiak and Markiewicz (2012 Filipiak, K., Markiewicz, A. (2012). On universal optimality of circular weakly neighbor balanced designs under an interference model. Comm. Stat. Theor Methods 41: 2356–2366.[Taylor &; Francis Online], [Web of Science ®] , [Google Scholar]) proved the universal optimality of circular weakly neighbor balanced designs (CWNBDs) under the interference model with fixed neighbor effects among the class of complete block designs. In two special cases where a CWNBD cannot exist, Filipiak et al. (2012 Filipiak, K., Markiewicz, A., Ró?ański, R. (2012). Maximal determinant over a certain class of matrices and its application to D-optimality of designs. Linear Algebra Appl. 436(4): 874–887.[Crossref], [Web of Science ®] , [Google Scholar]) characterized D-optimal designs. The aim of this paper is to show the universal optimality of CWNBDs and to characterize D-optimal designs under the interference model with random neighbor effects.     

Neighbor-Balanced Row-column Designs

In this article, row-column designs incorporating directional neighbor effects have been studied. A row-column design is said to be neighbor balanced if every treatment has all other treatments appearing as a neighbor a constant number of times. We considered here three different situations under row-column setup incorporating neighbor effects viz., row-column design with one-sided neighbor effect, two-sided neighbor effect, and four-sided neighbor effect. The information matrices for all the situations for estimating the direct and neighbor effects of treatments have been derived. Methods of constructing neighbor-balanced row-column designs have been developed and its characterization properties have been studied.     

Designs balanced for circular residual effects

Magda (1980) introduced a model for repeated measurements designs with a circular structure of the residual effects. He proved the universal optimality of circular balanced uniform designs over a subclass of the possible designs. We strengthen his result to optimality over the set of all designs with the same number of experimental units, periods and treatments.     

Some Classes of Binary Block Neighbor Designs

Neighbor designs are useful to neutralize the neighbor effects. In this paper two classes of these designs are constructed in circular binary blocks of size 4, 8, …, 24. First class consists of six infinite series of nearest neighbor designs in which each pair of distinct treatments appears once as neighbors. Second class also deals with six infinite series of these designs in which each pair of distinct treatments appears twice as neighbors. A catalog of nearest neighbor designs is also compiled in circular binary blocks for odd number of treatments from 23 to 99.     

Circular First- and Second-Order Balanced Repeated Measurements Designs

Sharma (1977 Sharma , V. K. ( 1977 ). Change-over designs with complete balance for first and second order residual effect . Canad. J. Statist. 5 : 121 – 132 .[Crossref] , [Google Scholar]) and Aggarwal et al. (2006 Aggarwal , M. L. , Deng , L.-Y. , Jha , M. K. ( 2006 ). Balanced residual treatment effects designs of first and second order . Statist. Probab. Lett. 76 : 597 – 600 .[Crossref], [Web of Science ®] , [Google Scholar]) considered non circular construction of first- and second-order balanced repeated measurements designs. Sharma et al. (2002 Sharma , V. K. , Varghese , C. , Jaggi , S. ( 2002 ). On optimality of change-over designs balanced for first and second order residual effects . Metron 60 : 153 – 162 . [Google Scholar]) constructed circular first- and second-order balanced repeated measurements designs only for a class with parameters (v, p = 3n, n = v ²) and also showed its universal optimality. In this article, we consider circular construction of first- and second-order balanced repeated measurements designs and strongly balanced repeated measurements designs by using the method of cyclic shifts. Some new circular designs with parameters (v, p, n) for cases p = v, p < v and p > v are given.     

Optimal Block Designs With Interference Effects From Neighboring Units Under a Non Additive Model

Here, the optimality of block design with interference effect from neighboring unit under a general non additive model is investigated, which allows for the presence of interactions among the treatments applied in the adjacent plots. A non additive model with interference × direct effects of treatments is considered as these effects contribute significantly to the response. A class of complete block designs balanced for interference effects from left neighboring unit is shown to be universally optimal for the estimation of direct and interference effects of treatments and two such series of designs have been constructed. Furthermore, considering direct treatment × block non additivity with interference effects, the optimality is studied and the optimal designs are obtained.     

Universally optimal designs under interference models with and without block effects

The concept of neighbor designs was introduced and defined by Rees (1967 Rees, D.H. (1967). Some designs of use in serology. Biometrics 23:779–791.[Crossref], [PubMed], [Web of Science ®] , [Google Scholar]) along with giving some methods of their construction. Henceforth, many methods of construction of neighbor designs as well as of their generalizations are available in the literature. However, there are only few results on their optimality. Therefore, the purpose of this article is to give an overview of study on this problem. Recent results on optimality of specified neighbor balanced designs under various interference models with block effects are presented and then these results are compared with respective models where block effects are not significant.     

On the optimality of the generalized room squares

Using a model given by Archbold and Johnson (1958) it is shown that the generalised Room square design is universally optimal for the estimation of the treatment effects. Further, if the variety-block design in a generalised Room square design is a BIBD, this design is also universally optimal for the estimation of the varietal effects.     

The Use of Balanced Incomplete Block Designs in Designing Randomized Response Surveys

This paper investigates the block total response method proposed by Raghavarao and Federer for providing accurate estimates of the base rates of sensitive characteristics during surveys. It determines the best balanced incomplete block design to use to estimate the base rates for three, four, five and six sensitive attributes respectively, given a maximum total number of 13 questions. The estimates obtained from this method have smaller variance than estimates obtained using the similar, but more popular, unmatched count technique.     

Designs balanced for neighbor effects in circular blocks of size six

The performance of a treatment is affected by the treatments applied to its adjacent plots, especially in the experiments of agriculture, horticulture, forestry, serology and industry. Neighbor designs ensure that treatment comparisons are least affected by neighbor effects, therefore, this is a rich field of investigation in statistics and in combinatorics. In this article, several series of neighbor balanced designs are considered in circular blocks of six units.     

Optimal repeated measurements designs for comparing test treatments with a control

A-optimal and mv optimal repeated measurments designs for comparing serveral test treatments with a control are considered. the models considered are basically of two types: without preperides and the cirular model. It is shown known that some known strongly balanced uniform repeated measurements designs can be modified to obtain optimal designs for this problem. Some other methods of finding optimal designs are also given.     

Nonproper variance balanced designs and optimality

This communication deals with the construction and optimality of non-proper (unequal block sized) variance balanced (VB) designs obtainable under linear homoscedastic normal model. Several methods of construction of non-proper VB designs have been given. Some constructed designs are universally optimal non-proper variance balanced designs.     

A review of uniform cross-over designs

Uniform cross-over designs form an important family of experimental designs. They have been applied in many scientific disciplines including clinical trials, agricultural studies and psychological experiments. In this paper we consider the four types of uniform cross-over design, as given by Williams [1949. Experimental designs balanced for the estimation of residual effects of treatments. Aust. J. Sci. Res. 2, 149–168], Cheng and Wu [1980. Balanced repeated measurements designs. Ann. Statist. 8, 1272–1283. Corrigendum 11 (1983) 349], Bate and Jones [2006. The construction of nearly balanced and nearly strongly balanced uniform cross-over designs. J. Statist. Plann. Inference 136, 3248–3267] and Kunert [1983. Optimal design and refinement of the linear model with applications to repeated measurements designs. Ann. Statist. 11, 247–257]. The efficiency of these designs, existence criteria and methods of construction are described.     

The Use of Treatment Concurrences to Assess Robustness of Binary Block Designs Against the Loss of Whole Blocks

Criteria are proposed for assessing the robustness of a binary block design against the loss of whole blocks, based on summing entries of selected upper non‐principal sections of the concurrence matrix. These criteria improve on the minimal concurrence concept that has been used previously and provide new conditions for measuring the robustness status of a design. The robustness properties of two‐associate partially balanced designs are considered and it is shown that two categories of group divisible designs are maximally robust. These results expand a classic result in the literature, obtained by Ghosh, which established maximal robustness for the class of balanced block designs.