Optimal simultaneous confidence bands in simple linear regression

A simultaneous confidence band provides useful information on the plausible range of an unknown regression model. For simple linear regression models, the most frequently quoted bands in the statistical literature include the hyperbolic band and the three-segment bands. One interesting question is whether one can construct confidence bands better than the hyperbolic and three-segment bands. The optimality criteria for confidence bands include the average width criterion considered by Gafarian (1964) and Naiman (1984) among others, and the minimum area confidence set (MACS) criterion of Liu and Hayter (2007). In this paper, two families of exact 1−α$1-\alpha$ confidence bands, the inner-hyperbolic bands and the outer-hyperbolic bands, which include the hyperbolic and three-segment bands as special cases, are introduced in simple linear regression. Under the MACS criterion, the best confidence band within each family is found by numerical search and compared with the hyperbolic band, the best three-segment band and with each other. The methodologies are illustrated with a numerical example and the Matlab programs used are available upon request.     

Confidence bands for the logistic and probit regression models over intervals

This article presents methods for the construction of two-sided and one-sided simultaneous hyperbolic bands for the logistic and probit regression models when the predictor variable is restricted to a given interval. The bands are constructed based on the asymptotic properties of the maximum likelihood estimators. Past articles have considered building two-sided asymptotic confidence bands for the logistic model, such as Piegorsch and Casella (1988 Piegorsch, W.W., Casella, G. (1988). Confidence bands for logistic regression with restricted predictor variables. Biometrics 44:739–750.[Crossref], [PubMed], [Web of Science ®] , [Google Scholar]). However, the confidence bands given by Piegorsch and Casella are conservative under a single interval restriction, and it is shown in this article that their bands can be sharpened using the methods proposed here. Furthermore, no method has yet appeared in the literature for constructing one-sided confidence bands for the logistic model, and no work has been done for building confidence bands for the probit model, over a limited range of the predictor variable. This article provides methods for computing critical points in these areas.     

Adaptive confidence bands in the nonparametric fixed design regression model

In this note, we consider the problem of the existence of adaptive confidence bands in the fixed design regression model, adapting ideas in Hoffmann and Nickl [(2011), ‘On Adaptive Inference and Confidence Bands’, Annals of Statistics, 39, 2383–2409] to the present case. In the course of the proof, we show that sup-norm adaptive estimators exist as well in the regression setting.     

Exact simultaneous confidence segments for all contrast comparisons

This paper provides an exact method to construct simultaneous confidence bands for all contrasts of several regression lines over a restricted explanatory variable. Due to the lack of exact methods in the literature, currently existing approaches consist mainly of simulation based approaches. Using confidence bands for regression analysis occurs ubiquitously in practice, for example, inference on the shelf-life or stability of a drug, on the reliability of an engineering system over time, on the environmental impact of a fertilizer in a field over time, to list just a few. The new method enhances currently existing approaches that are based on simulations.     

Easy-to-construct confidence bands for comparing two simple linear regression lines

This paper shows how to construct confidence bands for the difference between two simple linear regression lines. These confidence bands provide directly the information on the magnitude of the difference between the regression lines over an interval of interest and, as a by-product, can be used as a formal test of the difference between the two regression lines. Various different shapes of confidence bands are illustrated, and particular attention is paid towards confidence bands whose construction only involves critical points from standard distributions so that they are consequently easy to construct.     

Slope modified confidence bands for a simple linear regression model

Considerable attention has been directed in the statistical literature towards the construction of confidence bands for a simple linear regression model. These confidence bands allow the experimenter to make inferences about the model over a particular region of interest. However, in practice an experimenter will usually first check the significance of the regression line before proceeding with any further inferences such as those provided by the confidence bands. From a theoretical point of view, this raises the question of what the conditional confidence level of the confidence bands might be, and from a practical point of view it is unsatisfactory if the confidence bands contain lines that are inconsistent with the directional decision on the slope. In this paper it is shown how confidence bands can be modified to alleviate these two problems.     

Effective simultaneous confidence bands for repeated measurements in linear mixed-effect models

Linear mixed-effect (LME) models have been extensively accepted to analyse repeated measurements due to their flexibility and ability to handle subject-specific matters. The inclusion of random effects has resulted in much benefit with respect to estimation, but it is complicated to measure their impact on hypothesis testing. While the same complication is present in the construction of simultaneous confidence bands (SCBs), degrees of freedom (df) for SCBs have rarely been discussed unlike those for test statistics. This motivates us to propose the adoption of approximate df to construct SCBs in LME models. Simulation studies were performed to compare the performances of different calculations for the df. The results of simulations demonstrate the efficacy of the use of approximate df. In addition, our proposal allows line-segment SCBs developed under covariance models to function with LME models. Applications with real longitudinal datasets present consistent results with the simulation study.     

A ray method of confidence band construction for multiple linear regression models

This paper addresses the problem of confidence band construction for a standard multiple linear regression model. A “ray” method of construction is developed which generalizes the method of Graybill and Bowden [1967. Linear segment confidence bands for simple linear regression models. J. Amer. Statist. Assoc. 62, 403–408] for a simple linear regression model to a multiple linear regression model. By choosing suitable directions for the rays this method requires only critical points from t-distributions so that the confidence bands are easy to construct. Both one-sided and two-sided confidence bands can be constructed using this method. An illustration of the new method is provided.     

Bias-corrected confidence bands in nonparametric regression

Bias-corrected confidence bands for general nonparametric regression models are considered. We use local polynomial fitting to construct the confidence bands and combine the cross-validation method and the plug-in method to select the bandwidths. Related asymptotic results are obtained. Our simulations show that confidence bands constructed by local polynomial fitting have much better coverage than those constructed by using the Nadaraya–Watson estimator. The results are also applicable to nonparametric autoregressive time series models.     

Normal probability plots with confidence for the residuals in linear regression

Normal probability plots for a simple random sample and normal probability plots for residuals from linear regression are not treated differently in statistical text books. In the statistical literature, 1 ? α simultaneous probability intervals for augmenting a normal probability plot for a simple random sample are available. The first purpose of this article is to demonstrate that the tests associated with the 1 ? α simultaneous probability intervals for a simple random sample may have a size substantially different from α when applied to the residuals from linear regression. This leads to the second purpose of this article: construction of four normal probability plot-based tests for residuals, which have size α exactly. We then compare the powers of these four graphical tests and a non-graphical test for residuals in order to assess the power performances of the graphical tests and to identify the ones that have better power. Finally, an example is provided to illustrate the methods.     

Confidence intervals in regression utilizing prior information

We consider a linear regression model with regression parameter β=(_β1,…,_βp)$\beta =({\beta }_1,\dots ,{\beta }_p)$ and independent and identically N(0,σ²)$N(0,{\sigma }^2)$ distributed errors. Suppose that the parameter of interest is θ=a^Tβ$\theta =a^T\beta$ where a$a$ is a specified vector. Define the parameter τ=c^Tβ-t$\tau =c^T\beta -t$ where the vector c$c$ and the number t$t$ are specified and a$a$ and c$c$ are linearly independent. Also suppose that we have uncertain prior information that τ=0$\tau =0$. We present a new frequentist 1-α$1-\alpha$ confidence interval for θ$\theta$ that utilizes this prior information. We require this confidence interval to (a) have endpoints that are continuous functions of the data and (b) coincide with the standard 1-α$1-\alpha$ confidence interval when the data strongly contradict this prior information. This interval is optimal in the sense that it has minimum weighted average expected length where the largest weight is given to this expected length when τ=0$\tau =0$. This minimization leads to an interval that has the following desirable properties. This interval has expected length that (a) is relatively small when the prior information about τ$\tau$ is correct and (b) has a maximum value that is not too large. The following problem will be used to illustrate the application of this new confidence interval. Consider a 2×2$2\times 2$ factorial experiment with 20 replicates. Suppose that the parameter of interest θ$\theta$ is a specified simple   effect and that we have uncertain prior information that the two-factor interaction is zero. Our aim is to find a frequentist 0.95 confidence interval for θ$\theta$ that utilizes this prior information.     

Optimal Simultaneous Confidence Bands in Multiple Linear Regression with Predictor Variables Constrained in an Ellipsoidal Region

A simultaneous confidence band provides useful information on the plausible range of an unknown regression model function, just as a confidence interval gives the plausible range of an unknown parameter. For a multiple linear regression model, confidence bands of different shapes, such as the hyperbolic band and the constant width band, can be constructed and the predictor variable region over which a confidence band is constructed can take various forms. One interesting but unsolved problem is to find the optimal (shape) confidence band over an ellipsoidal region χ_E under the Minimum Volume Confidence Set (MVCS) criterion of Liu and Hayter (2007 Liu, W., Hayter, A.J. (2007). Minimum area confidence set optimality for confidence bands in simple linear regression. J. Amer. Statist. Assoc. 102:181–190.[Taylor & Francis Online], [Web of Science ®] , [Google Scholar]) and Liu et al. (2009 Liu, W., Bretz, F., Hayter, A.J., Wynn, H.P. (2009). Assessing non-superiority, non-inferiority or equivalence when comparing two regression models over a restricted covariate region. Biometrics 65:1279–1287.[Crossref], [PubMed], [Web of Science ®] , [Google Scholar]). This problem is challenging as it involves optimization over an unknown function that determines the shape of the confidence band over χ_E. As a step towards solving this difficult problem, in this paper, we introduce a family of confidence bands over χ_E, called the inner-hyperbolic bands, which includes the hyperbolic and constant-width bands as special cases. We then search for the optimal confidence band within this family under the MVCS criterion. The conclusion from this study is that the hyperbolic band is not optimal even within this family of inner-hyperbolic bands and so cannot be the overall optimal band. On the other hand, the constant width band can be optimal within the family of inner-hyperbolic bands when the region χ_E is small and so might be the overall optimal band.     

Joint impact of multiple observations on a subset of variables in multiple linear regression

In multiple linear regression analysis, each observation affects the fitted regression equation differently and has varying influences on the regression coefficients of the different variables. Chatterjee & Hadi (1988) have proposed some measures such as DSSE_ij (Impact on Residual Sum of Squares of simultaneously omitting the ith observation and the jth variable), F_j (Partial F-test for the jth variable) and F_j(i) (Partial F-test for the jth variable omitting the ith observation) to show the joint impact and the interrelationship that exists among a variable and an observation. In this paper we have proposed more extended form of those measures DSSE_IJ, F_J and F_J(I) to deal with the interrelationships that exist among the multiple observations and a subset of variables by monitoring the effects of the simultaneous omission of multiple variables and multiple observations.     

Confidence band for percentile line in multiple linear regression

We deal with the problem of estimating constructing a confidence band for the 100γth percentile line in the multiple linear regression model with independent identically normally distributed errors. A method for computing the exact Scheffé type confidence band over a limited space of the particular covariates region is suggested. A confidence band depends on an estimator of the percentile line. The confidence bands based on the different estimators of the percentile line are compared with respect to the average bandwidth.     

A confidence region with multiple intervals in multivariate bioassay

The exact confidence region for log relative potency resulting from likelihood score methods (Williams (1988) An exact confidence interval for the relative potency estimated from a multivariate bioassay, Biometrics, 44:861-868) will very likely consist of two disjoint confidence intervals. The two methods proposed by Williams which aim to select just one (the same) confidence interval from the confidence region are nearly – but not completely – consistent. The likelihood score interval and likelihood ratio interval are asymptotically equivalent. Williams's very strong claim concerning the confidence coefficient in the second selection method is still theoretically unproved; yet, simulations show that it is true for a wide range of practical experimental situations.