Permutation tests of scale using deviances

Robust tests for comparing scale parameters, based on deviances—absolute deviations from the median—are examined. Higgins (2004) proposed a permutation test for comparing two treatments based on the ratio of deviances, but the performance of this procedure has not been investigated. A simulation study examines the performance of Higgins’ test relative to other tests of scale utilizing deviances that have been shown in the literature to have good properties. An extension of Higgins’ procedure to three or more treatments is proposed, and a second simulation study compares its performance to other omnibus tests for comparing scale. While no procedure emerged as a preferred choice in every scenario, Higgins’ tests are found to perform well overall with respect to Type I error rate and power.     

The bahadur efficiency of paired versus joint ranking procedures for pa1rwtse multiple comparisons

The performance of paired versus joint ranking procedures for pairwise multiple comparisons is investigated using approxiirete Bahadur efficiency, When the populations to be compared are widely separated, or-when the. data arise from a shift model with an underlying unimodal density, the paired ranking procedure is found to be better for comparing two adjacent populations while the joint ranking procedure is more efficient for comparing the two most distant populations     

Asymptotic relative efficiency of designs for factorial paired comparison experiments

A general approach for comparing designs of paired comparison experiments on the basis of the asymptotic relative efficiencies, in the Bahadur sense, of their respective likelihood ratio tests is discussed and extended to factorials. Explicit results for comparing five designs of 2^q factorial paired comparison experiments are obtained. These results indicate that some of the designs which require comparison of fewer distinct pairs of treatments than does the completely balanced design are, generally, more efficient for detecting main effects and/or certain interactions. The developments of this paper generalize the work of Littell and Boyett (1977) for comparing two designs of R x C factorial paired comparison experiments.     

Selecting the best one of several meifull populations

Consider k(k ≥ 2) two-parameter Meibull populations. Using type II censored data we want to select a best population. Me have proposed procedures which can be used for maximum likelihood estimators or simplified linear estimators of Che unknown parameters. The ranking of the populations is done by comparing their reliabilities at certain fixed time or by comparing their 2-eh quantiles. In selected cases, the constants needed for the procedures are tabulated using Monte Carlo methods.     

An exact distribution-free test comparing two multivariate distributions based on adjacency

Summary.  A new test is proposed comparing two multivariate distributions by using distances between observations. Unlike earlier tests using interpoint distances, the new test statistic has a known exact distribution and is exactly distribution free. The interpoint distances are used to construct an optimal non-bipartite matching, i.e. a matching of the observations into disjoint pairs to minimize the total distance within pairs. The cross-match statistic is the number of pairs containing one observation from the first distribution and one from the second. Distributions that are very different will exhibit few cross-matches. When comparing two discrete distributions with finite support, the test is consistent against all alternatives. The test is applied to a study of brain activation measured by functional magnetic resonance imaging during two linguistic tasks, comparing brains that are impaired by arteriovenous abnormalities with normal controls. A second exact distribution-free test is also discussed: it ranks the pairs and sums the ranks of the cross-matched pairs.     

Comparing multiple treatments to both positive and negative controls

In the past, most comparison to control problems have dealt with comparing k test treatments to either positive or negative controls. Dasgupta et al. [2006. Using numerical methods to find the least favorable configuration when comparing k test treatments to both positive and negative controls. Journal of Statistical Computation and Simulation 76, 251–265] enumerate situations where it is imperative to compare several test treatments to both a negative as well as a positive control simultaneously. Specifically, the aim is to see if the test treatments are worse than the negative control, or if they are better than the positive control when the two controls are sufficiently apart. To find critical regions for this problem, one needs to find the least favorable configuration (LFC) under the composite null. In their paper, Dasgupta et al. [2006. Using numerical methods to find the least favorable configuration when comparing k test treatments to both positive and negative controls. Journal of Statistical Computation and Simulation 76, 251–265] came up with a numerical technique to find the LFC. In this paper we verify their result analytically. Via Monte Carlo simulation we compare the proposed method to the logical single step alternatives: Dunnett's [1955. A multiple comparison procedure for comparing several treatments with a control. Journal of the American Statistical Association 50, 1096–1121] or the Bonferroni correction. The proposed method is superior in terms of both the Type I error and the marginal power.     

Computation of the Two-Sample Smirnov Statistics

A simple method is given for evaluating the one- or two-sided Smirnov statistic for comparing two independent samples from continuous populations.     

Intermediate clinical events,surrogate markers and survival

This paper investigates one- and two-sample problems comparing survival times when an individual may experience an intermediate event prior to death or reaching some well defined endpoint. The intermediate event may be polychotomous. Patients experiencing the intermediate event may have an altered survival distribution after the intermediate event. Score tests are derived for testing if the occurrence of the intermediate event actually alters survival. These models have implications for evaluating therapies without randomization as well as strengthening the log rank test for comparing two survival distributions. The exact distribution of the score tests can be found by conditioning on both the waiting time and occurrence of the intermedate event.Deceased     

Minimum Size Survival Analysis Sampling Plans for Comparing Multiple Treatment Groups to a Single Control Group

We develop a sample size methodology that achieves specified Type-1 and Type-2 error rates when comparing the survivor functions of multiple treatment groups versus a control group. The designs will control family-wise Type-1 error rate. We assume the family of Weibull distributions adequately describes the underlying survivor functions, and we separately consider three of the most common study scenarios: (a) complete samples; (b) Type-1 censoring with a common censoring time; and (c) Type-1 censoring with an accrual period. A mice longevity study comparing the effect on survival of multiple low-calorie diets is used to motivate our work on this problem.     

Group selection for processes with multiple quality characteristics

Evaluating and comparing process capabilities are important tasks of production management. Manufacturers should apply the process with the highest capability among competing processes. A process group selection method is developed to solve the process selection problem based on overall yields. The goal is to select the processes with the highest overall yield among I processes under multiple quality characteristics, I > 2. The proposed method uses Bonferroni adjustment to control the overall error rate of comparing multiple processes. The critical values and the required sample sizes for designated powers are provided for practical use.     

Notes on testing carry-over effects in continuous data under an incomplete block crossover design

We consider hypothesis testing and estimation of carry-over effects in continuous data under an incomplete block crossover design when comparing two experimental treatments with a placebo. We develop procedures for testing differential carry-over effects based on the weighted-least-squares (WLS) method. We apply Monte Carlo simulations to evaluate the performance of these test procedures in a variety of situations. We use the data regarding the forced expiratory volume in one second (FEV₁) readings taken from a double-blind crossover trial comparing two different doses of formoterol with a placebo to illustrate the use of test procedures proposed here.     

Nonparametric Two-Sample Tests of Longitudinal Data with Termination Events

In longitudinal data, observations of response variables occur at fixed or random time points, and can be stopped by a termination event. When comparing longitudinal data for two groups, such irregular observation behavior must be considered to yield suitable results. In this article, we propose the use of nonparametric tests based on the difference between weighted cumulative mean functions for comparing two mean functions with an adjustment for difference in the timing of termination events. We also derive the asymptotic null distributions of the test statistics and examine their small sample properties through simulations. We apply our method to data from a study of liver cirrhosis.     

Poverty comparisons with common relative poverty lines

Relative poverty lines are increasingly being used in poverty comparison studies. Existing methods assume that the distributions being compared are distinct with independent relative poverty lines. However, this practice may be problematic when comparing two subgroups of a population. We follow up on a recent proposal for the usage of common relative poverty lines in such cases, and develop a test for comparing poverty between subgroups of a single population, using inequality restrictions. Monte Carlo experiments are conducted in order to examine the size and power of our proposed test. We illustrate our procedure using some U.S. household income data.     

Length minimization for Poisson confidence procedures

We study Poisson confidence procedures that potentially lead to short confidence intervals, investigating the class of all minimal cardinality procedures. We consider how length minimization should be properly defined, and show that Casella and Robert's (1989) criterion for comparing Poisson confidence procedures leads to a contradiction. We provide an alternative criterion for comparing length performance, identify the unique length optimal minimal cardinality procedure by this criterion, and propose a modification that eliminates an important drawback it possesses. We focus on procedures whose coverage never falls below the nominal level and discuss the case in which the nominal level represents mean coverage.     

Notes on interval estimation of the proportion ratio under a three-treatment three-period crossover trial

When comparing two experimental treatments with a placebo, we focus our attention on interval estimation of the proportion ratio (PR) of patient responses under a three-period crossover design. We propose a random effects exponential multiplicative risk model and derive asymptotic interval estimators in closed form for the PR between treatments and placebo. Using Monte Carlo simulations, we compare the performance of these interval estimators in a variety of situations. We use the data comparing two different doses of an analgesic with placebo for the relief of primary dysmenorrhea to illustrate the use of these interval estimators and the difference in estimates of the PR and odds ratio (OR) when the underlying relief rates are not small.     

Quantile estimation and comparing two independent groups with an approach based on percentile bootstrap

Although the most common approach for comparing two independent groups is on the basis of some measure of location, determination of the differences in the tails of the groups is often of interest. In this study, Harrell–Davis estimator, Sfakianakis–Verginis estimators and default quantile estimator of R are used in conjunction with a percentile bootstrap method with the aim of comparing two independent groups via the quantiles, and the relative efficiencies of Harrell–Davis and Sfakianakis–Verginis estimators are compared. General performance of Sfakianakis–Verginis estimators was much better than Harrell–Davis estimator in terms of both saving actual type I error and relative efficiency.     

Preliminary testing of the Cobb–Douglas production function and related inferential issues

In this article, we consider the multiple regression model in the presence of multicollinearity and study the performance of the preliminary test estimator (PTE) both analytically and computationally, when it is a priori suspected that some constraints may hold on the vector parameter space. The performance of the PTE is further analyzed by comparing the risk of some well-known estimators of the ridge parameter through an extensive Monte Carlo simulation study under some bounded and or asymmetric loss functions. An application of the Cobb–Douglas production function is included and from these results as well as the simulation studies, it is clear that the bounded linear exponential loss function outperforms the other loss functions across all the proposed ridge parameters by comparing the risk values.     

Comparing and testing order relations between percentile residual life functions

We consider the problem of comparing and testing order relations between percentile residual life functions. We introduce R-R plots and processes and develop a general approach for this problem.     

A Comparison of Bayes Factors for Separated Models: Some Simulation Results

Some alternative Bayes Factors: Intrinsic, Posterior, and Fractional have been proposed to overcome the difficulties presented when prior information is weak and improper prior are used. Additional difficulties also appear when the models are separated or non nested. This article presents both simulation results and some illustrative examples analysis comparing these alternative Bayes factors to discriminate among the Lognormal, the Weibull, the Gamma, and the Exponential distributions. Simulation results are obtained for different sample sizes generated from the distributions. Results from simulations indicates that these alternative Bayes factors are useful for comparing non nested models. The simulations also show some similar behavior and that when both models are true they choose the simplest model. Some illustrative example are also presented.     

A MODIFIED GROWTH CURVE MODEL AND ITS APPLICATION TO CLINICAL STUDIES

This paper considers a technique for applying growth curve analysis to data which are correlated across different groups. The method is illustrated using a study comparing three methods of suctioning an endotracheal tube.